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Natural killer cell activation in mice and men: different triggers for similar weapons?

Abstract：

:The signaling pathways that regulate B and T lymphocytes are remarkably conserved between humans and mice. However, recent evidence suggests that the pathways regulating natural killer (NK) cell activation may actually differ between these two species. We discuss the controversies in the field and propose that this divergence could be deceptive: despite some clear differences between human and mouse NK cell receptors, the many ways of activating NK cells and their functions may well be conserved.

journal_name

Nat Immunol

journal_title

Nature immunology

authors

Colucci F,Di Santo JP,Leibson PJ

doi

10.1038/ni0902-807

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

807-13

issue

9

eissn

1529-2908

issn

1529-2916

pii

ni0902-807

journal_volume

3

pub_type

杂志文章,评审

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