IgE reactivity to profilin in pollen-sensitized subjects with adverse reactions to banana and pineapple.

abstract：BACKGROUND:L-selectin (CD62L) and Mac-1 (CD11b/CD18) play a crucial role in the infiltration of eosinophils. However, changes in CD62L and CD11b expression on eosinophils after stimulation with cytokines were little studied. METHODS:Eosinophils in peripheral blood of healthy volunteers were purified and cultured with ...

journal_title：International archives of allergy and immunology

authors： Momose T,Okubo Y,Horie S,Takashi S,Tsukadaira A,Suzuki J,Isobe M,Sekiguchi M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Loss-of-function mutations of the filaggrin (FLG) gene cause an impaired skin barrier and increase the risk of atopic dermatitis. Interestingly, FLG mutations have also been found to be associated with a high risk of peanut allergy. OBJECTIVE:We investigated the association of FLG mutations with self-report...

journal_title：International archives of allergy and immunology

authors： Linneberg A,Fenger RV,Husemoen LL,Thuesen BH,Skaaby T,Gonzalez-Quintela A,Vidal C,Carlsen BC,Johansen JD,Menné T,Stender S,Melgaard M,Szecsi PB,Berg ND,Thyssen JP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Evidence regarding sublingual immunotherapy (SLIT) efficacy and its good safety profile has been demonstrated with pollen and house dust mite (HDM) allergens in the treatment of airway allergies. In addition, the use of grass pollen presents a SLIT disease-modifying treatment for respiratory allergies. OBJE...

journal_title：International archives of allergy and immunology

authors： Hagner S,Rask C,Brimnes J,Andersen PS,Raifer H,Renz H,Garn H

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:omega-5 gliadin is a major allergen in exercise-induced wheat allergy (EIWA), but it is also implicated in immediate-type reactions to wheat. An ImmunoCAP assay to measure omega-5 gliadin-specific IgE has become available. This study aimed to evaluate this new biological test in wheat allergy diagnosis and t...

journal_title：International archives of allergy and immunology

authors： Jacquenet S,Morisset M,Battais F,Denery-Papini S,Croizier A,Baudouin E,Bihain B,Moneret-Vautrin DA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Cow's milk (CM) allergy is the second most common food allergy developed during infancy in Japan. To identify predictors of persistent CM allergy, we investigated the tolerance acquisition rate based on an oral food challenge in children under 6 years of age, diagnosed with immediate-type CM allergy. METHOD...

journal_title：International archives of allergy and immunology

authors： Koike Y,Sato S,Yanagida N,Asaumi T,Ogura K,Ohtani K,Imai T,Ebisawa M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Egg allergy is one of the most common food allergies in children. The standard therapy for egg allergy is strict avoidance. Yet, there is considerable clinical and scientific interest in primary or secondary prevention. A major drawback of oral tolerance (OT) induction protocols, however, is the possibility ...

journal_title：International archives of allergy and immunology

authors： Hacini-Rachinel F,Vissers YM,Doucet-Ladevéze R,Blanchard C,Demont A,Perrot M,Panchaud A,Prioult G,Mercenier A,Nutten S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Exposure to the house dust mite Blomia tropicalis is increasingly being implicated as a major risk factor for asthma exacerbations in sensitized individuals. The objective of this study is to clone and characterize B. Tropicalis allergens in order to better define their role in allergic asthma. METHODS:A la...

journal_title：International archives of allergy and immunology

authors： Flores I,Mora C,Rivera E,Donnelly R,Montealegre F

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The lymphocyte transformation test (LTT) is used for in vitro diagnosis of drug hypersensitivity reactions. While its specificity is over 90%, sensitivity is limited and depends on the type of reaction, drug and possibly time interval between the event and analysis. Removal of regulatory T cells (Treg/CD25(h...

journal_title：International archives of allergy and immunology

authors： Srinoulprasert Y,Pichler WJ

更新日期：2014-01-01 00:00:00

abstract：:The modulatory role of hormones in the regulation of the immune response has been well documented. Here, we present some thoughts on how sex hormones affect immunity, particularly at mucosal sites. We further discuss the possible pitfalls and difficulties associated with analysis of the data. ...

journal_title：International archives of allergy and immunology

authors： Stanisz AM,Kataeva G,Bienenstock J

更新日期：1994-01-01 00:00:00

abstract：:Human colostrum and a high molecular weight colostrum fraction (HMWF; > 14,000 D) prevented the adhesion of localized adherent (LA+) O111:H-enteropathogenic Escherichia coli (EPEC) to HeLa cells. This effect was abolished after absorption with an O111:H-LA + EPEC strain, but absorption with a LA- strain of same seroty...

journal_title：International archives of allergy and immunology

authors： Camara LM,Carbonare SB,Silva ML,Carneiro-Sampaio MM

更新日期：1994-01-01 00:00:00

abstract：:This study concerned the way in which eosinophils adhere to their surroundings. Many fibrils were seen to adhere to the cell membrane of eosinophils migrating into the submucosa. Those eosinophils migrating into the epithelial layer adhered to the epithelial cells in 2 different ways: through the thin filaments bridgi...

journal_title：International archives of allergy and immunology

authors： Watanabe K

更新日期：1995-01-01 00:00:00

abstract：:Amino acid sequencing of the major mite allergen Der fII purified from mite body extract revealed that it is a mixture of at least two variants. Substitutions were found only at positions in which amino acid variations were predicted from the nucleotide sequences of three cloned cDNAs. When cDNAs corresponding to the ...

journal_title：International archives of allergy and immunology

authors： Nishiyama C,Yuuki T,Usui Y,Iwamoto N,Okumura Y,Okudaira H

更新日期：1994-09-01 00:00:00

abstract：INTRODUCTION:House dust mite contains several allergen components and causes perennial allergy. Lately, a new major allergen, Der p 23, was described with relatively high sensitization rates in different European Countries. In addition, Der p 23 is supposed to cause asthmatic disease. OBJECTIVE:We would like to questi...

journal_title：International archives of allergy and immunology

authors： Eder K,Becker S,Gellrich D,Zieglmayer P,Gröger M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Transforming growth factor-β1 (TGF-β1)-in-duced proliferation of airway smooth muscle cells plays critical roles in the development of airway remodeling. Six1 (sine oculis homeobox homolog 1) has been demonstrated to be involved in airway inflammation and remodeling in asthmatic mice. OBJECTIVES:The aim of ...

journal_title：International archives of allergy and immunology

authors： Yang Z,Qu Z,Yi M,Lv Z,Wang Y,Shan Y,Ran N,Liu X

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:alpha-Melanocyte-stimulating hormone (alpha-MSH) is a neuropeptide that controls melanogenesis in pigmentary cells. In addition, its potent immunomodulatory activity has been recently described in cutaneous inflammatory disorders. However the mechanism of such pollen allergies remains to be elucidated. The p...

journal_title：International archives of allergy and immunology

authors： Hiramoto K,Hashimoto M,Orita K,Jikumaru M,Sato EF,Inoue M

更新日期：2010-01-01 00:00:00

abstract：:Psoriasis (Ps) is a chronic, immune-mediated, skin inflammatory disease affecting up to 3% of the population worldwide. Different environmental triggers initiate this complex multifactorial syndrome. Many individuals affected by Ps (6-26%) develop inflammatory disease in other organs, often in the joints as in psorias...

journal_title：International archives of allergy and immunology

authors： Khmaladze Ia,Nandakumar KS,Holmdahl R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis (ACD) is an inflammatory skin disease caused by repeated skin exposure to contact allergens. The goal of this pilot study was to identify inflammatory proteins which can serve as biomarkers for ACD. METHODS:We measured levels of 102 cytokines, chemokines, and growth factors in th...

journal_title：International archives of allergy and immunology

authors： Zinkevičienė A,Kainov D,Lastauskienė E,Kvedarienė V,Bychkov D,Byrne M,Girkontaitė I

更新日期：2015-01-01 00:00:00

abstract：:In the present study, we investigated the role of resident peritoneal cells as well as the mediators involved in the eosinophil migration induced by large volumes of physiological saline. Two consecutive intraperitoneal injections of saline given 48 h apart, induced a selective recruitment of eosinophils into the cavi...

journal_title：International archives of allergy and immunology

authors： Oliveira SH,Faccioli LH,Cunha FQ,Ferreira SH

更新日期：1994-08-01 00:00:00

abstract：:We report a clinical study comparing the skin test reactivity to recombinant Aspergillus fumigatus allergen 1 (rAsp fI/a) in patients with atopic dermatitis and A. fumigatus sensitisation (n = 15), A. fumigatus-allergic patients with asthma (n = 10) and healthy control subjects (n = 10). All patients sensitised to A. ...

journal_title：International archives of allergy and immunology

authors： Disch R,Menz G,Blaser K,Crameri R

更新日期：1995-09-01 00:00:00

abstract：:We evaluated whether c-myc and ras P-21 oncogene expression could identify familial polyposis coli/Gardner's syndrome patients at risk for colon cancer. Monoclonal antibodies recognizing c-myc and ras P-21 proteins were used in immunohistochemistry to stain 26 paraffin-embedded tissue specimens collected over 12 years...

journal_title：International archives of allergy and immunology

authors： Yuwono M,Rossi TM,Fisher JE,Tjota A

更新日期：1996-09-01 00:00:00

abstract：:Hypersensitivity to latex proteins has been reported with increasing frequency in recent years. Elevated levels of latex specific IgE have been detected in the majority of these patients. Severe anaphylaxis and death resulting from latex exposure has also been reported. Nevertheless, the immune mechanism of latex alle...

journal_title：International archives of allergy and immunology

authors： Kurup VP,Kumar A,Choi H,Murali PS,Resnick A,Kelly KJ,Fink JN

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The cervical sympathetic trunk-submandibular gland (CST-SMG) axis plays an important role in inflammation. An immunoregulatory heptapeptide, submandibular gland peptide T (SGP-T), was isolated from submandibular glands, and several of its biological activities have been identified. RESULTS:SGP-T reduced sho...

journal_title：International archives of allergy and immunology

authors： Mathison RD,Davison JS,Befus AD

更新日期：1997-05-01 00:00:00

abstract：:Nitric oxide (NO) is a potent biological mediator, and has a regulatory role in a wide variety of cellular and tissue functions. In the upper and lower airways, NO has been suggested to be involved in different functions with regulatory, protective, defensive or damaging effects. It is obvious that NO plays an importa...

journal_title：International archives of allergy and immunology

authors： Sahin G,Klimek L,Mullol J,Hörmann K,Walther LE,Pfaar O

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The European tick, Argas reflexus, is an urban pest parasitizing urban pigeons and may cause a wide range of allergic reactions. METHODS:Specific IgE to A. reflexus, SDS-PAGE and IgE immunoblotting, performed with tick extract, were carried out in the sera of 6 patients who reported allergic reactions after...

journal_title：International archives of allergy and immunology

authors： Rolla G,Nebiolo F,Marsico P,Guida G,Bigo P,Riva G,Zanotta S

更新日期：2004-12-01 00:00:00

abstract：:The participation of platelets in the protection against larval Taenia taeniaeformis was studied. CB-17 SCID mice, susceptible to T. taeniaeformis, were protected against a challenge infection with T. taeniaeformis by the passive transfer of platelets from T. taeniaeformis-infected normal CB-17 mice, resistant to T. t...

journal_title：International archives of allergy and immunology

authors： Kakuda T,Ooi HK,Oku Y,Kamiya M

更新日期：1996-03-01 00:00:00

abstract：:Profilins are ubiquitous proteins, present in all eukaryotic cells and identified as allergens in pollen, latex and plant foods. The highly conserved structure justifies the cross-reactive nature of IgE antibodies against plant profilins and their designation as pan-allergens. Primary sensitization to profilin seems t...

journal_title：International archives of allergy and immunology

authors： Santos A,Van Ree R

更新日期：2011-01-01 00:00:00

abstract：:Human foamy virus (HFV) is a recently characterized member of the retrovirus subfamily Spumaretrovirinae. HFV has a complex structure: it encodes the classical three retroviral structural genes gag, pol and env, but also possesses additional regulatory, so-called bel sequences. Foamy viruses have been discussed occasi...

journal_title：International archives of allergy and immunology

authors： Wick G,Grubeck-Loebenstein B,Trieb K,Kalischnig G,Aguzzi A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Oxidants including reactive oxygen species have been indicated to play an important role in the pathogenesis of asthma. OBJECTIVE:We investigated oxidative status in patients with acute exacerbations of asthma and evaluated the therapeutic response using the D-ROM test which is simple to use and quick. MET...

journal_title：International archives of allergy and immunology

authors： Suzuki S,Matsukura S,Takeuchi H,Kawaguchi M,Ieki K,Odaka M,Watanabe S,Homma T,Dohi K,Aruga T,Sato M,Kurokawa M,Kokubu F,Adachi M

更新日期：2008-01-01 00:00:00

abstract：:Cross-linking of FcepsilonRI on mast cells elicits positive signal transduction cascades that lead to the release of a variety of proinflammatory mediators. Mouse mast cells also express gp49B1 on their surface, an immunoglobulin superfamily member that bears two immunoreceptor tyrosine-based inhibitory motifs in its ...

journal_title：International archives of allergy and immunology

authors： Katz HR

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The precise roles of T helper (Th)1-type and Th2-type cytokine responses in nickel (Ni)-induced allergic contact dermatitis have not yet been clearly defined. We investigated the involvement of Th2 cytokines in Ni-induced contact hypersensitivity reaction using GATA-3 transgenic (Tg) mice. METHODS:A Ni-tita...

journal_title：International archives of allergy and immunology

authors： Niiyama S,Tamauchi H,Amoh Y,Terashima M,Matsumura Y,Kanoh M,Habu S,Komotori J,Katsuoka K

更新日期：2010-01-01 00:00:00