Serum Biomarkers of Allergic Contact Dermatitis: A Pilot Study.

abstract：BACKGROUND:Patients with allergic rhinoconjunctivitis are susceptible to both nasal and ocular symptoms. The conjunctival provocation test (CPT) is an established diagnostic procedure used in allergic rhinoconjunctivitis, particularly to document a patient's current reactivity to allergens. To date, there are no intern...

journal_title：International archives of allergy and immunology

authors： Dogan S,Astvatsatourov A,Deserno TM,Bock F,Shah-Hosseini K,Michels A,Mösges R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Segmental allergen challenge is a powerful tool to study inflammatory reactions in asthmatic airways. There is little information on the early events at 5 min and 4 h after allergen challenge with respect to the cell influx and the chemokine interleukin-8 (IL-8). METHODS:Seven mild to moderate allergic asth...

journal_title：International archives of allergy and immunology

authors： Nocker RE,Out TA,Weller FR,Mul EP,Jansen HM,van der Zee JS

更新日期：1999-05-01 00:00:00

abstract：:Oxatomide (OXA), a histamine H1 receptor antagonist, is effective in the treatment of patients with allergic rhinitis, some allergic skin disorders, and bronchial asthma. We have characterized the effect of OXA on the immunologic release of preformed (histamine and tryptase) and de novo synthesized mediators (leukotri...

journal_title：International archives of allergy and immunology

authors： Patella V,de Crescenzo G,Marino O,Spadaro G,Genovese A,Marone G

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Asthma is a common co-morbidity of allergic rhinitis (AR). The prevalence of these two allergic diseases has increased in China and has been shown to cluster in families independently. This study evaluated the association between maternal AR (presenting with or without asthma) and the allergic conditions in ...

journal_title：International archives of allergy and immunology

authors： Wang QP,Wu KM,Li ZQ,Xue F,Chen W,Ji H,Wang BL

更新日期：2012-01-01 00:00:00

abstract：:The antigenic and allergenic characteristics of three bovine epithelial extracts, dander, skin scrapings and whole skin, were compared using IgE-ELISA inhibition and SDS-PAGE with immunoblotting. Cow dander extract was shown to contain more allergenic activity than skin scrapings or whole skin extracts which were need...

journal_title：International archives of allergy and immunology

authors： Ylönen J,Mäntyjärvi R,Taivainen A,Virtanen T

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Exposure to Aspergillus fumigatus allergens results in the sensitization and the development of allergic bronchopulmonary aspergillosis in susceptible individuals. Aspergillus antigen consists of a number of chemically diverse components and their cumulative or synergistic effect may result in disease. When ...

journal_title：International archives of allergy and immunology

authors： Kurup VP,Xia JQ,Shen HD,Rickaby DA,Henderson JD Jr,Fink JN,Chou H,Kelly KJ,Dawson CA

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Th2 cell infiltration is a characteristic feature of allergic chronic sinusitis. However, the mechanisms that cause the predominance of Th2 cells in this disease have yet to be clarified. The airway is often exposed to not only Th2 cytokines but also bacterial products such as lipopolysaccharides (LPS). A CC...

journal_title：International archives of allergy and immunology

authors： Fukumoto A,Nonaka M,Ogihara N,Pawankar R

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a multifaceted disease with a significant genetic component. The importance of taste receptor signaling has recently been highlighted in CRS; single nucleotide polymorphisms (SNPs) of bitter tastant-responsive G-protein-coupled receptors have been linked with CRS and with alte...

journal_title：International archives of allergy and immunology

authors： Purnell PR,Addicks BL,Zalzal HG,Shapiro S,Wen S,Ramadan HH,Setola V,Siderovski DP

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Transforming growth factor-β1 (TGF-β1)-in-duced proliferation of airway smooth muscle cells plays critical roles in the development of airway remodeling. Six1 (sine oculis homeobox homolog 1) has been demonstrated to be involved in airway inflammation and remodeling in asthmatic mice. OBJECTIVES:The aim of ...

journal_title：International archives of allergy and immunology

authors： Yang Z,Qu Z,Yi M,Lv Z,Wang Y,Shan Y,Ran N,Liu X

更新日期：2020-01-01 00:00:00

abstract：:Mercuric chloride (HgCl(2)) has been proposed to be a mitogen for human blood lymphocytes in vitro. In our previous study, we demonstrated that HgCl(2) preferentially stimulates the CD4+ T cell subset to blast transformation and DNA synthesis and that the reaction is dependent on CD14+ accessory cells. In order to cha...

journal_title：International archives of allergy and immunology

authors： Loftenius A,Ekstrand J,Möller E

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Lactobacillus casei is a nonpathogenic gram-positive bacterium widely used in dairy products and has been shown to enhance the cellular immunity of the host. METHODS:To examine the inhibitory effect of L. casei on IgE production, splenocytes obtained from ovalbumin (OVA)-primed BALB/c mice were restimulated...

journal_title：International archives of allergy and immunology

authors： Shida K,Makino K,Morishita A,Takamizawa K,Hachimura S,Ametani A,Sato T,Kumagai Y,Habu S,Kaminogawa S

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Mast cell-released chemical mediators such as histamine, leukotriene (LT) C(4) and prostaglandin (PG) D(2) lead to the onset of allergic disorders. ATP provided from glycolysis is essential for histamine release and LTC(4) secretion from mast cells upon Fc epsilon RI cross-linking, indicating that glucose is...

journal_title：International archives of allergy and immunology

authors： Kitahata Y,Nunomura S,Terui T,Ra C

更新日期：2010-01-01 00:00:00

abstract：:It has been well documented that environmental factors such as antigen-presenting cells and related cytokines can affect the development of T-helper cells. The purpose of this study was to investigate the role of different antigen-presenting cells on T-cell development. Ovalbumin (OVA) combined with complete Freud's a...

journal_title：International archives of allergy and immunology

authors： Chuang YH,Chiang BL,Chou CC,Hsieh KH

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Depression and smoking contribute to the prognosis of autoimmune rheumatoid arthritis (RA). Advanced glycation end products (AGEs) are also detected in RA patients. This study correlates RA in patients with various levels of depression and a history of smoking through the detection of antibodies against AGEs...

journal_title：International archives of allergy and immunology

authors： Alouffi S,Sherwani S,Al-Mogbel MS,Sherwani MKA,Ali Khan MW

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:House dust mite contains several allergen components and causes perennial allergy. Lately, a new major allergen, Der p 23, was described with relatively high sensitization rates in different European Countries. In addition, Der p 23 is supposed to cause asthmatic disease. OBJECTIVE:We would like to questi...

journal_title：International archives of allergy and immunology

authors： Eder K,Becker S,Gellrich D,Zieglmayer P,Gröger M

更新日期：2020-01-01 00:00:00

abstract：:Superoxide (O2-) and nitric oxide (NO) production by polymorphonuclear leukocyte (PMNs) and monocytes in patients with liver cirrhosis were evaluated. PMNs obtained from cirrhotic patients were less effective than those from controls in producing O2- after stimulation with opsonized zymosan, while they were more effec...

journal_title：International archives of allergy and immunology

authors： Masini E,Mugnai L,Foschi M,Laffi G,Gentilini P,Mannaioni PF

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Patients with chronic urticaria (CU) in the UK could be referred to health care professionals (HCPs) with diverse specialties using different guidelines. The aims of the present study were to determine which CU guidelines HCPs in the UK use, which tests they use for the diagnosis of CU, and how they manage C...

journal_title：International archives of allergy and immunology

authors： Wu CH,Ardern-Jones MR,Eren E,Venter C

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Obesity-associated asthma is characterized by type 2-low airway inflammation. We previously showed that EM900, which is a 12-membered nonantibiotic macrolide, suppressed airway inflammation in a mouse model of asthma exacerbation. The aim of this study was to clarify the effects of EM900 in obesity-associa...

journal_title：International archives of allergy and immunology

authors： Sadamatsu H,Takahashi K,Tashiro H,Kurihara Y,Kato G,Uchida M,Noguchi Y,Kurata K,Ōmura S,Sunazuka T,Kimura S,Sueoka-Aragane N

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The so-called 'latex-fruit syndrome' is a well-documented phenomenon in cross-reactive allergies. By contrast, there is a lack of information about allergy to exotic fruits in patients with a predominant pollen sensitization. Since the ubiquitous protein profilin has been identified as an allergen in natural...

journal_title：International archives of allergy and immunology

authors： Reindl J,Rihs HP,Scheurer S,Wangorsch A,Haustein D,Vieths S

更新日期：2002-06-01 00:00:00

abstract：:We have systematically investigated the capacity of highly purified human peripheral CD8+ T cells to produce interleukin (IL)-4 and interferon (IFN)-gamma when triggered by different stimuli. CD8+ T cells were isolated from peripheral blood by positive selection to > 99% purity and stimulated with one of three differe...

journal_title：International archives of allergy and immunology

authors： Li Y,Richards D,Noble A,Kemeny DM

更新日期：1995-05-01 00:00:00

abstract：:Mast cells in the tongue of the bat (Artibeus lituratus) show a well-developed Golgi area and abundant mitochondria in the granule-free perinuclear cytoplasm. Rough endoplasmic reticulum profiles, free ribosomes, mitochondria, bundles of filaments and a great number of secretory granules are found throughout the remai...

journal_title：International archives of allergy and immunology

authors： Oliani SM,Vugman I,Jamur MC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Basophils and mast cells are important initiator/effector cells capable of rapidly responding to IgE-mediated stimulation, but the precise mechanisms regulating their functions in vivo have not been fully identified. In this study, we assessed whether low levels of antigen can modulate activation of basophil...

journal_title：International archives of allergy and immunology

authors： Koketsu R,Yamaguchi M,Suzukawa M,Tanaka Y,Tashimo H,Arai H,Nagase H,Matsumoto K,Saito H,Ra C,Yamamoto K,Ohta K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Diethylhexyl phthalate (DEHP) and diisononyl phthalate (DINP), two commonly used plasticizers in flexible polyvinylchloride formulations, have potentially adverse effects on human health. However, the influence of these diphthalates on allergic responses remains unclear. In this study we examined the effects...

journal_title：International archives of allergy and immunology

authors： Lee MH,Park J,Chung SW,Kang BY,Kim SH,Kim TS

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Elicitation of contact hypersensitivity requires antigen-specific immunoglobulin M (IgM) antibodies that trigger recruitment of effector T cells to the local tissue. These antigen-specific IgM antibodies are produced by B-1-like 'initiator B cells'. In this study, we compared susceptibility to hapten-induced...

journal_title：International archives of allergy and immunology

authors： Itakura A,Ikutani M,Takatsu K,Kikuchi Y

更新日期：2013-01-01 00:00:00

abstract：:We report a clinical study comparing the skin test reactivity to recombinant Aspergillus fumigatus allergen 1 (rAsp fI/a) in patients with atopic dermatitis and A. fumigatus sensitisation (n = 15), A. fumigatus-allergic patients with asthma (n = 10) and healthy control subjects (n = 10). All patients sensitised to A. ...

journal_title：International archives of allergy and immunology

authors： Disch R,Menz G,Blaser K,Crameri R

更新日期：1995-09-01 00:00:00

abstract：:There is a great need to develop a method for making an accurate and reliable in vitro diagnosis of adverse hypersensitivity reactions to drugs. We measured the amount of sulfidoleukotriene (sLT) released from the peripheral blood leukocytes obtained from 25 patients who developed hypersensitivity reactions following ...

journal_title：International archives of allergy and immunology

authors： Kubota Y,Imayama S,Toshitani A,Miyahara H,Tanahashi T,Uemura Y,Koga T,Sugawara N,Kurimoto F,Hata K

更新日期：1997-12-01 00:00:00

abstract：:Eosinophils used to be thought of as regulators of allergic inflammation, but there is now evidence to the contrary; eosinophils have been found to be the major effector cells responsible for the late asthmatic response (LAR), airway hyperresponsiveness (AHR) and, at least in part, airway remodeling by releasing leuko...

journal_title：International archives of allergy and immunology

authors： Matsumoto K,Saito H

更新日期：2001-08-01 00:00:00

abstract：:Factors are discussed as potential diagnostic parameters of atopic disorders. The amounts of sCD23 in sera from newborn children (n = 4,329) were determined by radioimmunoassay with monoclonal antibodies specific for CD23. The sCD23 levels ranged between 0 and 81.5 ng/ml of CD23-specific mAb. Furthermore, the sera of ...

journal_title：International archives of allergy and immunology

authors： Bujanowski-Weber J,Knöller I,Wahn U,König W

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Pollen are monitored in Europe by a network of about 400 pollen traps, all operated manually. To date, automated pollen monitoring has only been feasible in areas with limited variability in pollen species. There is a need for rapid reporting of airborne pollen as well as for alleviating the workload of manu...

journal_title：International archives of allergy and immunology

authors： Oteros J,Pusch G,Weichenmeier I,Heimann U,Möller R,Röseler S,Traidl-Hoffmann C,Schmidt-Weber C,Buters JT

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Protective acquired immunity against helminths and allergic sensitisation are both characterised by high IgE antibody levels. Levels of IgE antibodies are naturally tightly regulated by several mechanisms including binding of the CD23 receptor. Following observations that helminth infections and allergic sen...

journal_title：International archives of allergy and immunology

authors： Rujeni N,Nausch N,Midzi N,Gwisai R,Mduluza T,Taylor DW,Mutapi F

更新日期：2013-01-01 00:00:00