Oral delivery of antigens in liposomes with some lipid compositions modulates oral tolerance to the antigens.

abstract：:RobA is a member of the XylS/AraC subfamily of DNA binding proteins, and when overexpressed, it induces multiple antibiotic resistance in Escherichia coli. In this study, we introduced a multicopy robA plasmid (pMEP1) and its derivative into OmpF mutants and an AcrAB-deficient mutant. We found that a decrease in susce...

journal_title：Microbiology and immunology

authors： Tanaka T,Horii T,Shibayama K,Sato K,Ohsuka S,Arakawa Y,Yamaki K,Takagi K,Ohta M

更新日期：1997-01-01 00:00:00

abstract：:Two methods of TSS diagnosis were evaluated: comparison of symptoms with clinical criteria and monitoring for evidence of selective activation of Vbeta2(+) T cells by the causative toxin, TSS toxin-1 (TSST-1). Ten patients with acute and systemic febrile infections caused by Staphylococcus aureus were monitored for in...

journal_title：Microbiology and immunology

authors： Matsuda Y,Kato H,Ono E,Kikuchi K,Muraoka M,Takagi K,Imanishi K,Itoh S,Itoh T,Ogawa T,Nitta K,Inokuchi S,Hibi T,Ohta H,Uchiyama T

更新日期：2008-11-01 00:00:00

abstract：:Botulinum neurotoxin (BoNT) is the causative agent of botulism in humans and animals. Only BoNT serotype A subtype 1 (BoNT/A1) is used clinically because of its high potency and long duration of action. BoNT/A1 and BoNT/A subtype 2 (BoNT/A2) have a high degree of amino acid sequence similarity in the light chain (LC) ...

journal_title：Microbiology and immunology

authors： Kohda T,Tsukamoto K,Torii Y,Kozaki S,Mukamoto M

更新日期：2020-07-01 00:00:00

abstract：:β-1,3-glucan is a major component of fungal cell walls with various biological activities, including effects on the production of inflammatory mediators in vivo and in vitro. However, few reports have examined its influence on the fungal cell itself. In this study, the influences of β-1,3-glucan on the growth and cell...

journal_title：Microbiology and immunology

authors： Ishibashi K,Kurone Y,Motoi M,Miura NN,Adachi Y,Shirasu Y,Ohno N

更新日期：2010-11-01 00:00:00

abstract：:Us3 is a serine-threonine protein kinase that is encoded by herpes simplex virus 1 (HSV-1). In experimental animal models of HSV infection, peripheral and intracranial inoculations can be used to study viral pathogenicity in peripheral sites (e.g., eyes and vagina) and central nervous systems (CNSs), respectively. In ...

journal_title：Microbiology and immunology

authors： Koyanagi N,Imai T,Arii J,Kato A,Kawaguchi Y

更新日期：2014-01-01 00:00:00

abstract：:Porins were prepared from smooth strain of Salmonella typhi 0-901 and chemotype rough mutant of S. typhimurium Ra-30. Porins could significantly stimulate the immune systems of mice. Immunization of mice with the porins provoked synthesis of anti-porin antibodies. Macrophages from the immunized mice showed increased c...

journal_title：Microbiology and immunology

authors： Tabaraie B,Sharma BK,Sharma PR,Sehgal R,Ganguly NK

更新日期：1994-01-01 00:00:00

abstract：:In order to analyze the host-parasite interactions in experimental trichomoniasis, the growth of Trichomonas foetus in the peritoneal cavity and changes in the peritoneal exudate cells were followed in mice treated with dextran sulfate 500 (DS 500), a known macrophage-toxic agent. Light microscopic observation showed ...

journal_title：Microbiology and immunology

authors： Oka Y,Hayashi H,Ishikawa F,Osaki H

更新日期：1980-01-01 00:00:00

abstract：:Sialyl Lewis X (SLe(x)), an E-selectin ligand, was conjugated with carboxymethylpullulan (CMPul) and the disposition characteristics of this conjugate after intravenous administration were investigated using mice with ear edema. The concentration of 3H-labeled SLe(x)-CMPul in the spleen was significantly high. When CM...

journal_title：Microbiology and immunology

authors： Horie K,Sakagami M,Kuramochi K,Ito T,Hamana H

更新日期：2000-01-01 00:00:00

abstract：:The function of MHC class II HLA-DR molecules expressed on a human B lymphoid progenitor cell line FL8.2.4.4 (abbreviated as FL4.4) was examined. FL4.4 cells expressed HLA-DR molecules and stimulation of the DR molecules by anti-DR mAb or by superantigen TSST-1 induced strong augmentation of homocytic aggregation and ...

journal_title：Microbiology and immunology

authors： Naitoh K,Ichigi Y,Miyake K,Muraguchi A,Kimoto M

更新日期：1994-01-01 00:00:00

abstract：:Irradiation treatment enhanced resistance of C57BL/6, but not BALB/c against Toxoplasma gondii infection. Six Gy-irradiated (IR) C57BL/6 recipients of B-2 cells from T. gondii-infected C57BL/6 died after infection. B-2 suppressor cells from infected C57BL/6 enhanced production of IL-4 and IL-10 in peritoneal exudate c...

journal_title：Microbiology and immunology

authors： Mun HS,Aosai F,Fang H,Piao LX,Winn T,Norose K,Yano A

更新日期：2005-01-01 00:00:00

abstract：:We developed the antigen capture enzyme-linked immunosorbent assay (ELISA) systems for quantification of Borna disease virus (BDV) major antigens, p40 and p24. Using these ELISAs, we quantified the two proteins in various BDV-infected materials, including the cell lysates and culture supernatants as well as the homoge...

journal_title：Microbiology and immunology

authors： Watanabe M,Zhong Q,Kobayashi T,Kamitani W,Tomonaga K,Ikuta K

更新日期：2000-01-01 00:00:00

abstract：:The NfxC-type mutant of Pseudomonas aeruginosa produces the MexEF-OprN efflux pump and down-regulates expression of the quorum-sensing-dependent efflux pump MexAB-OprM and production of virulence factors in the presence of an active transcriptional regulator, MexT. Consequently, these cells are resistant to chloramphe...

journal_title：Microbiology and immunology

authors： Uwate M,Ichise YK,Shirai A,Omasa T,Nakae T,Maseda H

更新日期：2013-04-01 00:00:00

abstract：:Stromal cell-derived factor-1 (SDF-1) is an efficacious chemoattractant for lymphocytes, monocytes and hematopoietic progenitor cells. In the present study, we examined whether SDF-1 has growth promoting activity on human peripheral T cells and analyzed the possible underlying signal transduction pathways. SDF-1 augme...

journal_title：Microbiology and immunology

authors： Yonezawa A,Hori T,Sakaida H,Uchiyama T

更新日期：2000-01-01 00:00:00

abstract：:The sensitivity of influenza rapid diagnostic tests (IRDTs) currently available in Japan for various influenza virus strains, including human H7N9 and H5N1 isolates, were compared and it was found that all of the IRDTs examined detected these viruses; however, their detection sensitivities differed. ...

journal_title：Microbiology and immunology

authors： Sakai-Tagawa Y,Ozawa M,Yamada S,Uchida Y,Saito T,Takahashi K,Sugaya N,Tashiro M,Kawaoka Y

更新日期：2014-10-01 00:00:00

abstract：:A mass outbreak of Escherichia coli O157:H45 was first reported in Japan in 1998. This pathogen was classified as an enteropathogenic E. coli (EPEC) O157 because it was characterized by the Shiga toxin gene (stx)-negative and bundle-forming pilus (bfp) gene-positive genotypes. In this study, we investigated the type I...

journal_title：Microbiology and immunology

authors： Abe A,Nagano H

更新日期：2000-01-01 00:00:00

abstract：:We have developed an indirect microhemagglutination test (IMHA) for detecting antibodies to Borrelia burgdorferi using formalin-fixed chicken erythrocytes sensitized with a sonicated extract of the bacteria. The specificity of IMHA for Lyme disease was compared with that of a conventional indirect immunoperoxidase tec...

journal_title：Microbiology and immunology

authors： Fujita H,Sato T,Ohara Y,Homma M

更新日期：1991-01-01 00:00:00

abstract：:The use of continuous free-flow electrophoresis for the purification of extracted lipopolysaccharides ( LPSs ) was investigated. Commercial (nucleic acid contaminated) LPS preparations, isolated by the hot phenol-water method of Westphal from Salmonella typhimurium and Escherichia coli 0111: B4, were analyzed. Continu...

journal_title：Microbiology and immunology

authors： Kuwae T,Kurata M

更新日期：1984-01-01 00:00:00

abstract：:Filamentous phage, fs1, was obtained from Vibrio cholerae O139. The lysogenized strains produced a large amount of fs1 phage in the culture supernatant. This phage was previously reported as novel fimbriae of that organism. The genome of the phage was a 6.5 kb single-stranded DNA. The capsid of fsl consists of a small...

journal_title：Microbiology and immunology

authors： Nakasone N,Honma Y,Toma C,Yamashiro T,Iwanaga M

更新日期：1998-01-01 00:00:00

abstract：:We have previously shown that immunization of mice with plasmid pMEa synthesizing Japanese encephalitis virus (JEV) envelope protein induced anti-JEV humoral and cellular immune responses. We now show that intra-muscular co-administration of mice with pMEa and pGM-CSF, encoding murine granulocyte-macrophage colony-sti...

journal_title：Microbiology and immunology

authors： Bharati K,Appaiahgari MB,Vrati S

更新日期：2005-01-01 00:00:00

abstract：:An antiserum against a fraction enriched for scrapie-associated fibrils (SAF), was examined for its effects on scrapie incubation period by inoculating mice either intraperitoneally or intracerebrally with various dilutions of the serum mixed with scrapie-infected mouse brain homogenate. After intraperitoneal inoculat...

journal_title：Microbiology and immunology

authors： Ito M,Shinagawa M,Doi S,Sasaki S,Isomura H,Takahashi K,Goto H,Sato G

更新日期：1988-01-01 00:00:00

abstract：:Intradermal injection of MY-1, a nucleic acid fraction extracted from Mycobacterium bovis strain BCG, induced in situ infiltration of mononuclear cells, most of which were asialo GM1 (GA1)-positive as determined by immunofluorescence microscopy. The infiltration occurred with as little as 1 microgram of MY-1 and laste...

journal_title：Microbiology and immunology

authors： Kuramoto E,Toizumi S,Shimada S,Tokunaga T

更新日期：1989-01-01 00:00:00

abstract：:Mammals have co-evolved with retroviruses, including lentiviruses, over a long period. Evidence supporting this contention is that viral infectivity factor (Vif) encoded by lentiviruses antagonizes the anti-viral action of cellular apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) of the host...

journal_title：Microbiology and immunology

authors： Yoshikawa R,Izumi T,Nakano Y,Yamada E,Moriwaki M,Misawa N,Ren F,Kobayashi T,Koyanagi Y,Sato K

更新日期：2016-06-01 00:00:00

abstract：:Molecular heterogeneity of the extracellular deoxyribonuclease (DNase) in group A streptococci was demonstrated in 42 clinical isolates. Although polyacrylamide gel electrophoretic patterns of the extracellular DNase of all the isolates were heterogeneous, they could be divided into five main patterns with respect to ...

journal_title：Microbiology and immunology

authors： Miyakawa Y,Yamada T,Shitara M,Fukazawa Y

更新日期：1985-01-01 00:00:00

abstract：:A human T cell hybridoma clone, F5, producing high levels of macrophage migration inhibitory factor (MIF) was established by the emetine-actinomycin D selection method. This clone produced two species of MIF which were separated on a Phenyl Sepharose column. We purified MIF-2 (the more hydrophobic species of the two) ...

journal_title：Microbiology and immunology

authors： Hirose S,Ooki S,Higuchi M,Osawa T

更新日期：1991-01-01 00:00:00

abstract：:We examined the mechanisms of fluconazole resistance in a fluconazole-resistant Candida albicans isolate from a Japanese patient with chronic mucocutaneous candidiasis. It was demonstrated that the highly resistant phenotype of this strain was associated with combined mechanisms of the energy-dependent reduced intrace...

journal_title：Microbiology and immunology

authors： Kamai Y,Maebashi K,Kudoh M,Makimura K,Naka W,Uchida K,Yamaguchi H

更新日期：2004-01-01 00:00:00

abstract：:The mechanisms of B cell tolerance were studied in an attempt to learn whether B cells rendered tolerant are present in the immune system in a potentially responsive form. The author tested the in vitro anti-trinitrophenyl (TNP) antibody-forming cell (anti-TNP AFC) response to TNP-immunogens and polyclonal B cell acti...

journal_title：Microbiology and immunology

authors： Uchiyama T

更新日期：1980-01-01 00:00:00

abstract：:EAEC is increasingly recognized as an emerging enteric pathogen. Typical EAEC expressing the AggR regulon have been proven to be an important cause of childhood diarrhea in industrialized countries as well as in the developing world, while atypical EAEC without this regulon have not been thoroughly investigated. To in...

journal_title：Microbiology and immunology

authors： Tokuda K,Nishi J,Imuta N,Fujiyama R,Kamenosono A,Manago K,Kawano Y

更新日期：2010-06-01 00:00:00

abstract：:Congenitally athymic BALB/cA nu/nu mice were employed to elucidate the role of the thymus in experimental Mycoplasma pulmonis strain m53 infection, and nu/+ mice were used for comparison. Chronic polyarthritis was frequently produced in both of nu/nu and nu/+ mice by intravenous injection of the organisms. Macroscopic...

journal_title：Microbiology and immunology

authors： Tanaka H

更新日期：1979-01-01 00:00:00

abstract：:This study revealed the presence of various rickettsial agents in mites from wild rodents collected in Southern Jeolla Province, Korea, by nested polymerase chain reaction (PCR) and sequence analysis of a partial citrate synthase and rickettsia outer membrane protein B genes. Rickettsial agents closely related to the ...

journal_title：Microbiology and immunology

authors： Choi YJ,Lee EM,Park JM,Lee KM,Han SH,Kim JK,Lee SH,Song HJ,Choi MS,Kim IS,Park KH,Jang WJ

更新日期：2007-01-01 00:00:00

abstract：:To establish an in vitro method of predicting in vivo efficacy of antifungal drugs against Candida albicans and Aspergillus fumigatus, the antifungal activities of fluconazole, itraconazole, and amphotericin B were determined in mouse serum. The minimum inhibitory concentration (MIC) of each drug was measured using mo...

journal_title：Microbiology and immunology

authors： Maki K,Watabe E,Iguchi Y,Nakamura H,Tomishima M,Ohki H,Yamada A,Matsumoto S,Ikeda F,Tawara S,Mutoh S

更新日期：2006-01-01 00:00:00