Abstract:
:Porins were prepared from smooth strain of Salmonella typhi 0-901 and chemotype rough mutant of S. typhimurium Ra-30. Porins could significantly stimulate the immune systems of mice. Immunization of mice with the porins provoked synthesis of anti-porin antibodies. Macrophages from the immunized mice showed increased capacity to generate oxygen free radicals, and lymphocytes from these mice showed proliferative response to the porins. Thus porins may play a role in providing protection from salmonellosis by stimulating the antibody production and increasing the capacity of macrophages to generate oxygen free radicals along with stimulation of lymphocytes.
journal_name
Microbiol Immunoljournal_title
Microbiology and immunologyauthors
Tabaraie B,Sharma BK,Sharma PR,Sehgal R,Ganguly NKdoi
10.1111/j.1348-0421.1994.tb01823.xsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
561-5issue
7eissn
0385-5600issn
1348-0421journal_volume
38pub_type
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journal_title:Microbiology and immunology
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更新日期:1993-01-01 00:00:00