Latent class analysis of DSM-IV schizotypal personality disorder criteria in psychiatric patients.

abstract：:The present article reports findings on intelligence and personality functioning during the school period and at adolescence in a sample of kibbutz and urban Israeli children at risk for schizophrenia, as measured by a standard psychological test battery. On the first round of testing it was found that the index subje...

journal_title：Schizophrenia bulletin

authors： Sohlberg SC

更新日期：1985-01-01 00:00:00

abstract：:Medical geology is the application of trace element geography to epidemiology. This approach is used to compare the geographic distribution of selenium and other trace elements in soil and food with that of high schizophrenia rates in the United States and other countries. Since the comparison is most statistically si...

journal_title：Schizophrenia bulletin

authors： Brown JS Jr

更新日期：1994-01-01 00:00:00

abstract：:It is increasingly evident that the brain is not truly an immune privileged site and that cells of the central nervous system are sensitive to the inflammation generated when the brain is fighting off infection. Among the many microorganisms that have access to the brain, the apicomplexan protozoan Toxoplasma gondii h...

journal_title：Schizophrenia bulletin

authors： Xiao J,Prandovszky E,Kannan G,Pletnikov MV,Dickerson F,Severance EG,Yolken RH

更新日期：2018-08-20 00:00:00

abstract：:We report a 25-year followup of a group of 50 children at genetic risk for schizophrenia (by virtue of having a parent with the disorder) and 50 matched controls. The children who eventually developed schizophrenia spectrum disorders, including schizophrenia, were identifiable by cognitive-psychophysiological, neuroin...

journal_title：Schizophrenia bulletin

authors： Mirsky AF,Kugelmass S,Ingraham LJ,Frenkel E,Nathan M

更新日期：1995-01-01 00:00:00

abstract：:The question of whether schizophrenia is associated with structural or functional abnormalities of the nervous system, or both, has become the principal focus of biological studies of schizophrenia. Computed tomography studies have revealed ventricular enlargement and cortical atrophy in a subgroup of schizophrenic pa...

journal_title：Schizophrenia bulletin

authors： Meltzer HY

更新日期：1987-01-01 00:00:00

abstract：:Antipsychotics, cognitive behavioral therapy (CBT), and omega-3-fatty acids have been found superior to control conditions as regards prevention of psychosis in people at-risk of first-episode psychosis. However, no large-scale trial evaluating the differential efficacy of CBT and antipsychotics has been performed yet...

journal_title：Schizophrenia bulletin

authors： Bechdolf A,Müller H,Stützer H,Wagner M,Maier W,Lautenschlager M,Heinz A,de Millas W,Janssen B,Gaebel W,Michel TM,Schneider F,Lambert M,Naber D,Brüne M,Krüger-Özgürdal S,Wobrock T,Riedel M,Klosterkötter J,PREVENT stu

更新日期：2011-09-01 00:00:00

abstract：:Catechol-O-methyl transferase (COMT) is a catabolic enzyme involved in the degradation of a number of bioactive molecules; of principal interest to psychiatry, these include dopamine. The enzyme is encoded by the COMT gene. COMT is located (along with 47 other genes) in a fragment of chromosome 22q11 which when delete...

journal_title：Schizophrenia bulletin

authors： Williams HJ,Owen MJ,O'Donovan MC

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:In light of the evidence for brain white matter (WM) abnormalities in schizophrenia, study of normal WM maturation in adolescence may provide critical insights relevant to the neurodevelopment of the disorder. Voxel-wise diffusion tensor imaging (DTI) studies have consistently demonstrated increases in fract...

journal_title：Schizophrenia bulletin

authors： Peters BD,Szeszko PR,Radua J,Ikuta T,Gruner P,DeRosse P,Zhang JP,Giorgio A,Qiu D,Tapert SF,Brauer J,Asato MR,Khong PL,James AC,Gallego JA,Malhotra AK

更新日期：2012-11-01 00:00:00

abstract：:Advances in psychopharmacology have produced medications with substantial efficacy in the treatment of positive and negative symptoms of schizophrenia and the prevention of relapse or symptom exacerbation after an acute episode. In the clinical setting, the individual patient's acceptance or rejection of prescribed ph...

journal_title：Schizophrenia bulletin

authors： Fenton WS,Blyler CR,Heinssen RK

更新日期：1997-01-01 00:00:00

abstract：:Although glutamate was first hypothesized to be involved in the pathophysiology of schizophrenia in the 1980s, it was the demonstration that N-methyl-D-aspartate (NMDA) receptor antagonists, the dissociative anesthetics, could replicate the full range of psychotic, negative, cognitive, and physiologic features of schi...

journal_title：Schizophrenia bulletin

authors： Coyle JT

更新日期：2012-09-01 00:00:00

abstract：:Ventricle-to-brain ratio (VBR) was measured from the computed tomographic (CT) scans of 33 very recent-onset psychotic patients. Illness severity and positive and negative symptoms were also assessed in 21 of these patients with schizophreniform disorder. Forty-five neurology patients served as controls. Analyses reve...

journal_title：Schizophrenia bulletin

authors： Holsenbeck LS 3rd,Davidson LM,Hostetter RE,Casanova MF,Taylor DO,Kelley CT,Perrotta C Jr,Borison RL,Diamond B

更新日期：1992-01-01 00:00:00

abstract：:Antistigma campaigns have been promoting a medical view of schizophrenia. Given the growing body of research finding negative associations between biogenetic (BG) causal attributions and stigmatizing attitudes, this approach must be reappraised. The present study investigates the impact of different psychoeducational ...

journal_title：Schizophrenia bulletin

authors： Lincoln TM,Arens E,Berger C,Rief W

更新日期：2008-09-01 00:00:00

abstract：:Genetic variants conferring risk for schizophrenia (SCZ) have been extensively studied, but the role of posttranscriptional mechanisms in SCZ is not well studied. Here we performed the first genome-wide microRNA (miRNA) expression profiling in serum-derived exosome from 49 first-episode, drug-free SCZ patients and 46 ...

journal_title：Schizophrenia bulletin

authors： Du Y,Yu Y,Hu Y,Li XW,Wei ZX,Pan RY,Li XS,Zheng GE,Qin XY,Liu QS,Cheng Y

更新日期：2019-10-24 00:00:00

abstract：:Genome-wide association studies (GWASs) have identified >100 susceptibility loci for schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by numerous genetic variants but with small effect size. We conducted a GWAS in the Japanese (JPN) population (a) to detect novel SCZ-susceptibility gene...

journal_title：Schizophrenia bulletin

authors： Ikeda M,Takahashi A,Kamatani Y,Momozawa Y,Saito T,Kondo K,Shimasaki A,Kawase K,Sakusabe T,Iwayama Y,Toyota T,Wakuda T,Kikuchi M,Kanahara N,Yamamori H,Yasuda Y,Watanabe Y,Hoya S,Aleksic B,Kushima I,Arai H,Takaki

更新日期：2019-06-18 00:00:00

abstract：:Discussion of the positive vs. negative distinction often fails to address whether this distinction refers to symptoms, syndromes, or diseases. Symptoms and syndromes are etiologically nonspecific, while diseases have a specific identifiable pathophysiology or etiology. The positive vs. negative distinction is sometim...

journal_title：Schizophrenia bulletin

authors： Andreasen NC

更新日期：1985-01-01 00:00:00

abstract：:Cognitive deficits are a central and debilitating aspect of schizophrenia and other major mental illnesses. Although they are largely refractory to pharmacotherapy, multiple studies have now shown that large and lasting improvements in cognition can result from behavioral interventions. We will review our work over th...

journal_title：Schizophrenia bulletin

authors： Wexler BE,Bell MD

更新日期：2005-10-01 00:00:00

abstract：:The purpose of this study was (1) to identify the demographic and psychosocial characteristics of Korean-Americans with schizophrenia, and (2) to compare the demographic and psychosocial characteristics of Korean-Americans with schizophrenia to African-American, Latino, and Euro-American individuals with schizophrenia...

journal_title：Schizophrenia bulletin

authors： Bae SW,Brekke JS

更新日期：2002-01-01 00:00:00

abstract：:Psychiatric research, including the search for predisposing genes, has tended to proceed under the assumptions that schizophrenia and bipolar disorder, as defined in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and International Statistical Classification of Diseases, 10th Revision, are discr...

journal_title：Schizophrenia bulletin

authors： Owen MJ,Craddock N,Jablensky A

更新日期：2007-07-01 00:00:00

abstract：:Aerobic exercise has been shown to improve symptoms in multiepisode schizophrenia, including cognitive impairments, but results are inconsistent. Therefore, we evaluated the effects of an enriched environment paradigm consisting of bicycle ergometer training and add-on computer-assisted cognitive remediation (CACR) tr...

journal_title：Schizophrenia bulletin

authors： Malchow B,Keller K,Hasan A,Dörfler S,Schneider-Axmann T,Hillmer-Vogel U,Honer WG,Schulze TG,Niklas A,Wobrock T,Schmitt A,Falkai P

更新日期：2015-07-01 00:00:00

abstract：:Recent years have witnessed widespread interest in the early phase of schizophrenia and other psychotic disorders. Strategies have been introduced to attempt to identify individuals in the prepsychotic or prodromal phase. The most widely used of these approaches is the ultra-high risk (UHR) approach, which combines kn...

journal_title：Schizophrenia bulletin

authors： Nelson B,Yung AR,Bechdolf A,McGorry PD

更新日期：2008-03-01 00:00:00

abstract：:The purpose of the study was to examine (1) to which negative symptoms schizophrenia patients attribute distress and (2) whether clinical variables can predict the levels of reported distress. With the help of a research assistant, 86 hospitalized patients completed a self-rating scale for negative symptoms. The 21 it...

journal_title：Schizophrenia bulletin

authors： Selten JP,Wiersma D,van den Bosch RJ

更新日期：2000-01-01 00:00:00

abstract：:The original CHoice of Outcome In Cbt for psychosEs (CHOICE) measure was designed in collaboration with experts by experience as a patient-reported "Psychological Recovery" outcome measure for cognitive-behavioral therapy for psychosis (CBTp). A short version (CHOICE-SF) was developed to use as a brief outcome measure...

journal_title：Schizophrenia bulletin

authors： Webb R,Bartl G,James B,Skan R,Peters E,Jones AM,Garety P,Kuipers E,Hayward M,Greenwood K

更新日期：2020-11-20 00:00:00

abstract：:The psychometric high-risk strategy represents a useful methodologic adjunct to the traditional genetic high-risk research approach in the study of the etiology and development of schizophrenia. During the past 15 years, considerable research activity has focused on psychometrically identified individuals hypothesized...

journal_title：Schizophrenia bulletin

authors： Lenzenweger MF

更新日期：1994-01-01 00:00:00

abstract：:A greater understanding of the links between cognitive and social functioning changes is needed to refine cognitive treatments for schizophrenia. To date, studies have been cross-sectional, and few have investigated the impact of cognitive change. This single-blind randomized controlled trial explored the links betwee...

journal_title：Schizophrenia bulletin

authors： Reeder C,Smedley N,Butt K,Bogner D,Wykes T

更新日期：2006-10-01 00:00:00

abstract：:The chronic methamphetamine (MAP) intoxication model of schizophrenia in animals is outlined. The idea originated from the clinical and neurochemical similarities between MAP psychosis and schizophrenia that were found during the decade immediately after World War II when MAP abuse occurred in epidemic proportions in ...

journal_title：Schizophrenia bulletin

authors： Machiyama Y

更新日期：1992-01-01 00:00:00

abstract：:Poor insight into illness is considered the primary cause of treatment noncompliance in schizophrenia. In this article, we critically discuss the predominant conceptual accounts of poor insight, which consider it as an ineffective self-reflection, caused either by psychological defenses or impaired metacognition. We a...

journal_title：Schizophrenia bulletin

authors： Henriksen MG,Parnas J

更新日期：2014-05-01 00:00:00

abstract：:Deluded people differ from nondeluded controls on attributional style questionnaires and probabilistic-reasoning and theory-of-mind (ToM) tasks. No study to date has examined the relations between these 3 reasoning anomalies in the same individuals so as to evaluate their functional independence and potentially inform...

journal_title：Schizophrenia bulletin

authors： Langdon R,Ward PB,Coltheart M

更新日期：2010-03-01 00:00:00

abstract：:Spatial working memory (WM) processing has 3 distinct phases: encoding, maintenance, and retrieval and its dysfunction is a core feature in schizophrenia. We examined phase-specific brain activations associated with spatial WM in first-degree relatives of schizophrenia (genetic high risk, GHR), ultra-high risk (UHR) s...

journal_title：Schizophrenia bulletin

authors： Choi JS,Park JY,Jung MH,Jang JH,Kang DH,Jung WH,Han JY,Choi CH,Hong KS,Kwon JS

更新日期：2012-11-01 00:00:00

abstract：:Clozapine has been found to be superior to traditional neuroleptics in the treatment of refractory schizophrenia and is increasingly being used to treat schizophrenia, affective disorders, some neurological disorders, and aggression. For many patients, clozapine offers new hope for the successful pharmacological manag...

journal_title：Schizophrenia bulletin

authors： Young CR,Bowers MB Jr,Mazure CM

更新日期：1998-01-01 00:00:00

abstract：:Evidence suggests that dissociation is associated with psychotic experiences, particularly hallucinations, but also other symptoms. However, until now, symptom-specific relationships with dissociation have not been comprehensively synthesized. This is the first prospectively registered (CRD42017058214) meta-analysis t...

journal_title：Schizophrenia bulletin

authors： Longden E,Branitsky A,Moskowitz A,Berry K,Bucci S,Varese F

更新日期：2020-03-18 00:00:00