Can antistigma campaigns be improved? A test of the impact of biogenetic vs psychosocial causal explanations on implicit and explicit attitudes to schizophrenia.

abstract：:Recently published data from the Roscommon Family Study show that a parental diagnosis of schizotypal disorder (SPD) has a significant and specific impact on the risk for schizophrenia in siblings of index probands with schizophrenia spectrum disorders. The distribution patterns of risks for schizophrenia and SPD in p...

journal_title：Schizophrenia bulletin

authors： Battaglia M,Bellodi L

更新日期：1996-01-01 00:00:00

abstract：:Individuals with psychoses have brain alterations, particularly in frontal and temporal cortices, that may be particularly prominent, already at illness onset, in those more likely to have poorer symptom remission following treatment with the first antipsychotic. The identification of strong neuroanatomical markers of...

journal_title：Schizophrenia bulletin

authors： Dazzan P,Lawrence AJ,Reinders AATS,Egerton A,van Haren NEM,Merritt K,Barker GJ,Perez-Iglesias R,Sendt KV,Demjaha A,Nam KW,Sommer IE,Pantelis C,Wolfgang Fleischhacker W,van Rossum IW,Galderisi S,Mucci A,Drake R,Lewis S

更新日期：2020-10-15 00:00:00

abstract：:The demand for information by relatives and the success of family intervention programs with an initial didactic component has resulted in a proliferation of educational interventions in schizophrenia. The present study assesses the impact of a single educational session on relatives of recent-onset schizophrenic pati...

journal_title：Schizophrenia bulletin

authors： Cozolino LJ,Goldstein MJ,Nuechterlein KH,West KL,Snyder KS

更新日期：1988-01-01 00:00:00

abstract：:Secondary sources continue to cite a one-page preliminary note about the Michigan State Psychotherapy Project, ignoring fuller reports in print. Relevant experience and training are critical to quality control of psychotherapy in schizophrenia research. This investigation is unique in that "experienced" meant that the...

journal_title：Schizophrenia bulletin

authors： Karon BP

更新日期：1978-01-01 00:00:00

abstract：:A critique is offered of Samuels' article suggesting that reported sex differences in concordance rates for schizophrenia are either methodological artifacts or a function of sociological processes. Evidence of sex differences in age of onset, clinical expression, concordance rates among primary relatives, and premorb...

journal_title：Schizophrenia bulletin

authors： Lewine RR

更新日期：1979-01-01 00:00:00

abstract：:Gender effects have been reported quite consistently in schizophrenia, with male patients having an earlier age of onset, poorer functional outcome, greater negative symptoms and cognitive impairment, and less severe positive symptoms. Because age of onset, cognitive impairments, and negative symptoms are all correlat...

journal_title：Schizophrenia bulletin

authors： Moriarty PJ,Lieber D,Bennett A,White L,Parrella M,Harvey PD,Davis KL

更新日期：2001-01-01 00:00:00

abstract：:A selective review of the negative symptoms of schizophrenia is an appropriate article to result from the festschrift honoring William T. Carpenter Jr, as he has made substantial contributions in this area. This review assesses progress in 3 areas in which he has been an important investigator: the distinction between...

journal_title：Schizophrenia bulletin

authors： Kirkpatrick B

更新日期：2014-03-01 00:00:00

abstract：:Considerable research has documented the stigmatization of people with mental illnesses and its negative consequences. Recently it has been shown that stigma may also seriously affect families of psychiatric patients, but little empirical research has addressed this problem. We examine perceptions of and reactions to ...

journal_title：Schizophrenia bulletin

authors： Phelan JC,Bromet EJ,Link BG

更新日期：1998-01-01 00:00:00

abstract：:Disrupted thalamo-cortical connectivity is regarded as a core psychopathology in patients diagnosed with schizophrenia. However, whether the thalamo-cortical white matter connectivity is disrupted before the onset of psychosis is still unknown. To determine this gap in knowledge, the strength of thalamo-cortical white...

journal_title：Schizophrenia bulletin

authors： Cho KI,Shenton ME,Kubicki M,Jung WH,Lee TY,Yun JY,Kim SN,Kwon JS

更新日期：2016-05-01 00:00:00

abstract：:In contrast with issues of consent capacity, financial capacity has received surprisingly little clinical or ethical attention in the psychiatric literature. Issues of financial capacity emerge frequently regarding clients with serious mental illness (SMI), and their resolution has practical and ethical significance f...

journal_title：Schizophrenia bulletin

authors： Marson DC,Savage R,Phillips J

更新日期：2006-01-01 00:00:00

abstract：:Visual illusions allow for strong tests of perceptual functioning. Perceptual impairments can produce superior task performance on certain tasks (i.e., more veridical perception), thereby avoiding generalized deficit confounds while tapping mechanisms that are largely outside of conscious control. Using a task based o...

journal_title：Schizophrenia bulletin

authors： Horton HK,Silverstein SM

更新日期：2011-07-01 00:00:00

abstract：:To better characterize hippocampal pathophysiology in schizophrenia, we conducted a longitudinal study evaluating hippocampal functional connectivity during resting state, using seeds prescribed in its anterior and posterior regions. We enrolled 34 unmedicated patients with schizophrenia or schizoaffective disorder (S...

journal_title：Schizophrenia bulletin

authors： Kraguljac NV,White DM,Hadley N,Hadley JA,Ver Hoef L,Davis E,Lahti AC

更新日期：2016-07-01 00:00:00

abstract：:The establishment of the new diagnostic category, Schizotypal Personality Disorder (SPD), has stimulated biological studies of patients with this disorder. Such studies offer the potential of better understanding the diagnosis and treatment of SPD as well as more clearly defining the boundaries of the schizophrenic di...

journal_title：Schizophrenia bulletin

authors： Siever LJ

更新日期：1985-01-01 00:00:00

abstract：:Schizophrenia (SCZ) is associated with differences in subcortical brain volumes and intracranial volume (ICV). However, little is known about the underlying etiology of these brain alterations. Here, we explored whether brain structure volumes and SCZ share genetic risk factors. Using conditional false discovery rate ...

journal_title：Schizophrenia bulletin

authors： Smeland OB,Wang Y,Frei O,Li W,Hibar DP,Franke B,Bettella F,Witoelar A,Djurovic S,Chen CH,Thompson PM,Dale AM,Andreassen OA

更新日期：2018-06-06 00:00:00

abstract：INTRODUCTION:Abnormalities in the neurophysiological measures P300 amplitude and latency constitute endophenotypes for psychosis. Disrupted-in-Schizophrenia-1 (DISC1) has been proposed as a promising susceptibility gene for schizophrenia, and a previous study has suggested that it is associated with P300 deficits in sc...

journal_title：Schizophrenia bulletin

authors： Shaikh M,Hall MH,Schulze K,Dutt A,Li K,Williams I,Walshe M,Constante M,Broome M,Picchioni M,Toulopoulou T,Collier D,Stahl D,Rijsdijk F,Powell J,Murray RM,Arranz M,Bramon E

更新日期：2013-01-01 00:00:00

abstract：:Antipsychotic medications are viewed as cornerstones for both the short-term and long-term treatment of schizophrenia. However, evidence on long-term (10 or more years) efficacy of antipsychotics is mixed. Double-blind discontinuation studies indicate significantly more relapses in unmedicated schizophrenia patients i...

journal_title：Schizophrenia bulletin

authors： Harrow M,Jobe TH

更新日期：2013-09-01 00:00:00

abstract：:Schizophrenia affects people of all age groups. Treatment plans for older adults with schizophrenia must consider the effects of age on the course of the illness as well as on the response to antipsychotics and to psychosocial interventions. Positive symptoms of schizophrenia tend to become less severe, substance abus...

journal_title：Schizophrenia bulletin

authors： Jeste DV,Maglione JE

更新日期：2013-09-01 00:00:00

abstract：:The poverty and lack of social role in the lives of many people with schizophrenia seem similar to those of people in long-term unemployment, raising the possibility that there may be some commonalities in their time use and community functioning. To test this possibility, the social anxiety, time use, and activity pa...

journal_title：Schizophrenia bulletin

authors： Hayes RL,Halford WK

更新日期：1996-01-01 00:00:00

abstract：:Randomized controlled trials for antipsychotic drugs have a variety of design features suited to diverse purposes. Efficacy (or explanatory) trials seek to establish if a drug can reduce psychotic symptoms under ideal circumstances. To isolate drug effects, researchers enroll carefully selected patients. Specialized r...

journal_title：Schizophrenia bulletin

authors： Stroup TS,Geddes JR

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The homicide of strangers by people with psychosis, referred to here as "stranger homicides," are rare and tragic events that generate adverse publicity for mental health services and have resulted in significant changes in mental health policy and law. AIM:To estimate the incidence of stranger homicides, u...

journal_title：Schizophrenia bulletin

authors： Nielssen O,Bourget D,Laajasalo T,Liem M,Labelle A,Häkkänen-Nyholm H,Koenraadt F,Large MM

更新日期：2011-05-01 00:00:00

abstract：:Educating the public that mental illness is a brain disease is a popular strategy for combating mental illness stigma. Evidence suggests that while such an approach reduces blame for mental illness, it may unintentionally exacerbate other components of stigma, particularly the benevolence and dangerousness stigmas. Co...

journal_title：Schizophrenia bulletin

authors： Corrigan PW,Watson AC

更新日期：2004-01-01 00:00:00

abstract：:Phenotypic heterogeneity within patients and controls may explain why the genetic variants contributing to schizophrenia risk explain only a fraction of the heritability. The aim of this study is to investigate quantitative and qualitative differences in psychosis symptoms in a sample including psychosis patients, the...

journal_title：Schizophrenia bulletin

authors： Derks EM,Allardyce J,Boks MP,Vermunt JK,Hijman R,Ophoff RA,GROUP.

更新日期：2012-05-01 00:00:00

abstract：:This article focuses on the schizophrenic disorganization syndrome, which was initially described by Bleuler (who used the term "dissociation") as lying at the heart of schizophrenia. While adopting a neo-Bleulerian approach, we describe schizophrenic disorganization using a pathogenetic hypothesis and a three-part st...

journal_title：Schizophrenia bulletin

authors： Hardy-Baylé MC,Sarfati Y,Passerieux C

更新日期：2003-01-01 00:00:00

abstract：:Discussion of the positive vs. negative distinction often fails to address whether this distinction refers to symptoms, syndromes, or diseases. Symptoms and syndromes are etiologically nonspecific, while diseases have a specific identifiable pathophysiology or etiology. The positive vs. negative distinction is sometim...

journal_title：Schizophrenia bulletin

authors： Andreasen NC

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Given the evidence that reasoning biases contribute to delusional persistence and change, several research groups have made systematic efforts to modify them. The current experiment tested the hypothesis that targeting reasoning biases would result in change in delusions. METHODS:One hundred and one partici...

journal_title：Schizophrenia bulletin

authors： Garety P,Waller H,Emsley R,Jolley S,Kuipers E,Bebbington P,Dunn G,Fowler D,Hardy A,Freeman D

更新日期：2015-03-01 00:00:00

abstract：:The electroencephalogram (EEG) recorded from the human scalp is widely used to study cognitive and brain functions in schizophrenia. Current research efforts are primarily devoted to the assessment of event-related potentials (ERPs) and event-related oscillations (EROs), extracted from the ongoing EEG, in patients wit...

journal_title：Schizophrenia bulletin

authors： van der Stelt O,Belger A

更新日期：2007-07-01 00:00:00

abstract：:Clozapine can cause severe adverse effects yet it is associated with reduced mortality risk. We test the hypothesis this association is due to increased clinical monitoring and investigate risk of premature mortality from natural causes. We identified 14 754 individuals (879 deaths) with serious mental illness (SMI) i...

journal_title：Schizophrenia bulletin

authors： Hayes RD,Downs J,Chang CK,Jackson RG,Shetty H,Broadbent M,Hotopf M,Stewart R

更新日期：2015-05-01 00:00:00

abstract：:This study compared the performance of 39 biological relatives of persons with schizophrenia to that of 30 normal adult controls on graphesthesia processing, a complex somatosensory processing task. The relatives performed significantly worse on the graphesthesia task compared to the healthy controls. The relatives an...

journal_title：Schizophrenia bulletin

authors： Chang BP,Lenzenweger MF

更新日期：2004-01-01 00:00:00

abstract：:The early detection and intervention in psychoses prior to their first episode are presently based on the symptomatic ultra-high-risk and the basic symptom criteria. Current models of symptom development assume that basic symptoms develop first, followed by attenuated and, finally, frank psychotic symptoms, though int...

journal_title：Schizophrenia bulletin

authors： Jimeno N,Gomez-Pilar J,Poza J,Hornero R,Vogeley K,Meisenzahl E,Haidl T,Rosen M,Klosterkötter J,Schultze-Lutter F

更新日期：2020-07-08 00:00:00

abstract：:The sex chromosomes are strong candidates for a genetic locus for schizophrenia and the affective psychoses. Gender differences in the clinical expression of illness and familial risks, concordance for gender and illness in relatives, and an association of X chromosome anomalies with psychosis suggest an X chromosome ...

journal_title：Schizophrenia bulletin

authors： DeLisi LE,Crow TJ

更新日期：1989-01-01 00:00:00