Investigating graphesthesia task performance in the biological relatives of schizophrenia patients.

abstract：:The deficit syndrome is thought to characterize a pathophysiologically distinct subgroup of patients with schizophrenia. Supporting this notion, prior research examining the neuropsychological correlates of the deficit syndrome has suggested the presence of a differential impairment in frontal and parietal functions. ...

journal_title：Schizophrenia bulletin

authors： Cohen AS,Saperstein AM,Gold JM,Kirkpatrick B,Carpenter WT Jr,Buchanan RW

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Patients with deficit schizophrenia differ from nondeficit patients with schizophrenia relative to several neurobiological correlates and relative to the risk factors of family history and season of birth. Exposure to human herpesviruses is a possible risk factor for schizophrenia. We hypothesized that there...

journal_title：Schizophrenia bulletin

authors： Dickerson F,Kirkpatrick B,Boronow J,Stallings C,Origoni A,Yolken R

更新日期：2006-04-01 00:00:00

abstract：Objective:Evidence suggests that social skills training (SST) is an efficacious intervention for negative symptoms in psychosis, whereas evidence of efficacy in other psychosis symptom domains is limited. The current article reports a comprehensive meta-analytic review of the evidence for SST across relevant outcome me...

journal_title：Schizophrenia bulletin

authors： Turner DT,McGlanaghy E,Cuijpers P,van der Gaag M,Karyotaki E,MacBeth A

更新日期：2018-04-06 00:00:00

abstract：:The Seventh International Congress on Schizophrenia Research was held in Santa Fe, New Mexico, in April 1999. This was the largest Congress meeting to date, with almost 1,000 presentations that covered all aspects of schizophrenia research. This article provides an account of the Congress proceedings. Several research...

journal_title：Schizophrenia bulletin

authors： Buckley PF,Buchanan RW,Tamminga CA,Schulz SC

更新日期：2000-01-01 00:00:00

abstract：:Empirically supported treatments for schizophrenia now include a variety of psychosocial interventions, such as social skills training, vocational rehabilitation, and psychotherapy. As awareness of the functional importance of neurocognitive impairments in schizophrenia has increased, interest in treatments to improve...

journal_title：Schizophrenia bulletin

authors： Twamley EW,Jeste DV,Bellack AS

更新日期：2003-01-01 00:00:00

abstract：:Research into tardive dyskinesia, an involuntary movement disorder secondary to chronic neuroleptic treatment, has so far produced conflicting results with no clear clinical applications. Heterogeneous diagnostic criteria, research designs, and rating scales, plus an emphasis on single-drug trials, are probably respon...

journal_title：Schizophrenia bulletin

authors： Nasrallah HA

更新日期：1979-01-01 00:00:00

abstract：:Schizophrenia is a chronic brain disorder that affects about 1.1% of the adult US population annually. Hallucinations, delusions, and impaired reality testing are prominent symptoms of the disorder. Modeling these symptoms is difficult because it is unclear how to assess impaired reality testing in animals. Animals ca...

journal_title：Schizophrenia bulletin

authors： McDannald M,Schoenbaum G

更新日期：2009-07-01 00:00:00

abstract：:There is some evidence that schizotypal traits are related to a genetic or familial liability to develop schizophrenia. However, it is unclear whether the number of schizotypal traits is elevated in parents of schizophrenia patients compared with controls. This study used the Schizotypal Personality Questionnaire to i...

journal_title：Schizophrenia bulletin

authors： Appels MC,Sitskoorn MM,Vollema MG,Kahn RS

更新日期：2004-01-01 00:00:00

abstract：:The purpose of this study was (1) to identify the demographic and psychosocial characteristics of Korean-Americans with schizophrenia, and (2) to compare the demographic and psychosocial characteristics of Korean-Americans with schizophrenia to African-American, Latino, and Euro-American individuals with schizophrenia...

journal_title：Schizophrenia bulletin

authors： Bae SW,Brekke JS

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Task-based functional neuroimaging studies of schizophrenia have not yet replicated the increased coordinated hyperactivity in speech-related brain regions that is reported with symptom-capture and resting-state studies of hallucinations. This may be due to suboptimal selection of cognitive tasks. METHODS:I...

journal_title：Schizophrenia bulletin

authors： Lavigne KM,Rapin LA,Metzak PD,Whitman JC,Jung K,Dohen M,Lœvenbruck H,Woodward TS

更新日期：2015-01-01 00:00:00

abstract：:As part of a long-term study in schizophrenia, a model of family intervention has been developed which attempts to diminish relapse rates of schizophrenic patients. This model reflects theoretical and research findings which suggest that certain patients have a "core psychological deficit" that might increase vulnerab...

journal_title：Schizophrenia bulletin

authors： Anderson CM,Hogarty GE,Reiss DJ

更新日期：1980-01-01 00:00:00

abstract：:Increased latency of stimulus encoding is presented as a central deficit in schizophrenia cognition. Encoding, here, entails the internal representation of presenting stimuli in a format facilitating their implementation in other cognitive processes, such as those taking place in working memory. Historical roots of su...

journal_title：Schizophrenia bulletin

authors： Neufeld RW

更新日期：2007-07-01 00:00:00

abstract：:The dopamine hypothesis of schizophrenia implies that alterations in the dopamine system cause functional abnormalities in the brain that may converge to aberrant salience attribution and eventually lead to psychosis. Indeed, widespread brain disconnectivity across the psychotic spectrum has been revealed by resting-s...

journal_title：Schizophrenia bulletin

authors： Rössler J,Unterassner L,Wyss T,Haker H,Brugger P,Rössler W,Wotruba D

更新日期：2019-04-25 00:00:00

abstract：:We examined neurocognitive correlates of three dimensions of schizotypy in 63 healthy first degree relatives of schizophrenia patients. Neurocognitive measures of attention, verbal memory, and prefrontal functioning were combined with self-report and interview measures of schizotypy. State-psychopathology (anxiety and...

journal_title：Schizophrenia bulletin

authors： Vollema MG,Postma B

更新日期：2002-01-01 00:00:00

abstract：:Problems in psychiatric classification have impeded research into psychopathology for more than a century. Here, I briefly review several new approaches to solving this problem, including the internalizing-externalizing-psychosis spectra, the 5-factor model of psychotic symptoms, and the more recent network approach. ...

journal_title：Schizophrenia bulletin

authors： Bentall RP

更新日期：2014-07-01 00:00:00

abstract：:Between 5% and 10% of people with psychosis will die by suicide, a rate which is 20-75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals of psychotic experiences and negative metacognitive beliefs about losing menta...

journal_title：Schizophrenia bulletin

authors： Hutton P,Di Rienzo F,Turkington D,Spencer H,Taylor P

更新日期：2019-01-01 00:00:00

abstract：:Designs of clinical trials that will permit evaluation of independent, additive, and interactive effects of drugs and psychosocial treatments are described. The central feature of such designs is that they incorporate control conditions for both classes of treatment. Data from the articles in this issue are drawn upon...

journal_title：Schizophrenia bulletin

authors： Schooler NR

更新日期：1980-01-01 00:00:00

abstract：:This study examined the content of subscales within a multidimensional scale of self-reported schizotypy and their subsequent interrelationship by means of confirmatory factor analysis (CFA). Neither single-factor nor four-factor models provided good fits to the data; two-factor and three-factor models showed very goo...

journal_title：Schizophrenia bulletin

authors： Venables PH,Rector NA

更新日期：2000-01-01 00:00:00

abstract：:The left superior temporal sulcus (STS) plays an important role in integrating audiovisual information and is functionally connected to disparate regions of the brain. For the integration of gesture information in an abstract sentence context (metaphoric gestures), intact connectivity between the left STS and the infe...

journal_title：Schizophrenia bulletin

authors： Straube B,Green A,Sass K,Kircher T

更新日期：2014-07-01 00:00:00

abstract：:Genome-wide association studies (GWASs) have identified >100 susceptibility loci for schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by numerous genetic variants but with small effect size. We conducted a GWAS in the Japanese (JPN) population (a) to detect novel SCZ-susceptibility gene...

journal_title：Schizophrenia bulletin

authors： Ikeda M,Takahashi A,Kamatani Y,Momozawa Y,Saito T,Kondo K,Shimasaki A,Kawase K,Sakusabe T,Iwayama Y,Toyota T,Wakuda T,Kikuchi M,Kanahara N,Yamamori H,Yasuda Y,Watanabe Y,Hoya S,Aleksic B,Kushima I,Arai H,Takaki

更新日期：2019-06-18 00:00:00

abstract：BACKGROUND:Insight into the neural mechanisms underlying the shared and disparate features of schizophrenia (SZ) and bipolar disorder (BD) is limited. The amygdala and prefrontal cortex (PFC) appear to have crucial roles in SZ and BD, yet abnormalities appear to manifest differently in the 2 disorders. METHODS:Eightee...

journal_title：Schizophrenia bulletin

authors： Liu H,Tang Y,Womer F,Fan G,Lu T,Driesen N,Ren L,Wang Y,He Y,Blumberg HP,Xu K,Wang F

更新日期：2014-03-01 00:00:00

abstract：:Standardized recovery criteria go beyond symptom remission and put special emphasis on personal and social functioning in residence, work, and leisure. Against this background, evidence-based integrated approaches combining cognitive remediation with social skills therapy show promise for improving functional recovery...

journal_title：Schizophrenia bulletin

authors： Roder V,Mueller DR,Schmidt SJ

更新日期：2011-09-01 00:00:00

abstract：:This study examined the course of illness and factors affecting it in schizophrenias with onset between the ages of 14 and 18. Noteworthy in comparison to findings from other followup studies is the higher proportion of chronic courses of illness, about 50 percent. In addition, the type of course of illness correspond...

journal_title：Schizophrenia bulletin

authors： Krausz M,Müller-Thomsen T

更新日期：1993-01-01 00:00:00

abstract：:The goals of the project Social Cognition and Functioning in Schizophrenia (SCAF) were to (1) identify the domains to target from social neuroscience for translation to clinical schizophrenia research, (2) identify the paradigms that represent these domains for which the neural substrates are well documented, (3) adap...

journal_title：Schizophrenia bulletin

authors： Green MF,Penn DL

更新日期：2013-11-01 00:00:00

abstract：:Schizotypal disorder is characterized by odd behavior and attenuated forms of schizophrenic features without the manifestation of overt and sustained psychoses. Past studies suggest that schizotypal disorder shares biological and psychological commonalties with schizophrenia. Structural magnetic resonance imaging (MRI...

journal_title：Schizophrenia bulletin

authors： Takayanagi Y,Sasabayashi D,Takahashi T,Furuichi A,Kido M,Nishikawa Y,Nakamura M,Noguchi K,Suzuki M

更新日期：2020-02-26 00:00:00

abstract：:Evidence suggests that dissociation is associated with psychotic experiences, particularly hallucinations, but also other symptoms. However, until now, symptom-specific relationships with dissociation have not been comprehensively synthesized. This is the first prospectively registered (CRD42017058214) meta-analysis t...

journal_title：Schizophrenia bulletin

authors： Longden E,Branitsky A,Moskowitz A,Berry K,Bucci S,Varese F

更新日期：2020-03-18 00:00:00

abstract：BACKGROUND:Working memory (WM) deficit is a key feature of schizophrenia that relates to a generalized neural inefficiency of extensive brain areas. To date, it remains unknown how these distributed regions are systemically organized at the connectome level and how the disruption of such organization brings about the W...

journal_title：Schizophrenia bulletin

authors： Yang J,Pu W,Wu G,Chen E,Lee E,Liu Z,Palaniyappan L

更新日期：2020-07-08 00:00:00

abstract：:In a prospective study involving 161 patients discharged from inpatient psychiatric treatment, outcome data were obtained for 93 percent of the patients 1 year after clinic discharge. Sixty-seven percent of the patients were directly interviewed for the followup examination. Outcome data for symptomatology, relapses, ...

journal_title：Schizophrenia bulletin

authors： Pietzcker A,Gaebel W

更新日期：1987-01-01 00:00:00

abstract：:There is an increasing emphasis on identifying individuals with schizophrenia earlier and earlier in their disease process, with the assumption that earlier identification translates into earlier treatment, which translates into improved outcome. Unfortunately, one age cohort, children under 13 years of age, have been...

journal_title：Schizophrenia bulletin

authors： Ross RG,Schaeffer J,Compagnon N,Heinlein S,Beresford C,Farley G

更新日期：2003-01-01 00:00:00

abstract：:The article that follows is part of the Schizophrenia Bulletin's ongoing First Person Account series. We hope that mental health professionals--the Bulletin's primary audience--will take this opportunity to learn about the issues and difficulties confronted by consumers of mental health care. In addition, we hope that...

journal_title：Schizophrenia bulletin

authors： Ribar AV

更新日期：2004-01-01 00:00:00