Deficit schizophrenia: association with serum antibodies to cytomegalovirus.

abstract：:Spatial working memory (WM) processing has 3 distinct phases: encoding, maintenance, and retrieval and its dysfunction is a core feature in schizophrenia. We examined phase-specific brain activations associated with spatial WM in first-degree relatives of schizophrenia (genetic high risk, GHR), ultra-high risk (UHR) s...

journal_title：Schizophrenia bulletin

authors： Choi JS,Park JY,Jung MH,Jang JH,Kang DH,Jung WH,Han JY,Choi CH,Hong KS,Kwon JS

更新日期：2012-11-01 00:00:00

abstract：:One neuropathological feature of schizophrenia is a diminished number of dendritic spines in the prefrontal cortex and hippocampus. The neuregulin 1 (Nrg1) system is involved in the plasticity of dendritic spines, and chronic stress decreases dendritic spine densities in the prefrontal cortex and hippocampus. Here, we...

journal_title：Schizophrenia bulletin

authors： Clarke DJ,Chohan TW,Kassem MS,Smith KL,Chesworth R,Karl T,Kuligowski MP,Fok SY,Bennett MR,Arnold JC

更新日期：2019-03-07 00:00:00

abstract：:In contrast with issues of consent capacity, financial capacity has received surprisingly little clinical or ethical attention in the psychiatric literature. Issues of financial capacity emerge frequently regarding clients with serious mental illness (SMI), and their resolution has practical and ethical significance f...

journal_title：Schizophrenia bulletin

authors： Marson DC,Savage R,Phillips J

更新日期：2006-01-01 00:00:00

abstract：:To understand the biological significance of a decreased platelet MAO activity in schizophrenia, it is important to answer many questions about the basic molecular properties of the enzyme. The past decade has witnessed a huge expansion of research in this area which has provided some of these answers. A wide variety ...

journal_title：Schizophrenia bulletin

authors： Edwards DJ

更新日期：1980-01-01 00:00:00

abstract：:The "Praecox Feeling" (PF) is a classical concept referring to a characteristic feeling of bizarreness experienced by a psychiatrist while encountering a person with schizophrenia. Although the PF used to be considered a core symptom of the schizophrenia spectrum, it fell into disuse since the spread of operationalize...

journal_title：Schizophrenia bulletin

authors： Gozé T,Moskalewicz M,Schwartz MA,Naudin J,Micoulaud-Franchi JA,Cermolacce M

更新日期：2019-09-11 00:00:00

abstract：:Studies on the long-term development and early predictors of treatment-resistant schizophrenia (TRS) and clozapine-resistant TRS (CR-TRS) in patients with first-episode schizophrenia-spectrum disorders (FES) are limited and have not considered the impact of early intervention services (EIS). This study aimed to explor...

journal_title：Schizophrenia bulletin

authors： Chan SKW,Chan HYV,Honer WG,Bastiampillai T,Suen YN,Yeung WS,Lam M,Lee WK,Ng RMK,Hui CLM,Chang WC,Lee EHM,Chen EYH

更新日期：2020-10-12 00:00:00

abstract：:In light of the large number of studies published since the 2004 update of Schizophrenia Patient Outcomes Research Team psychopharmacological treatment recommendations, we conducted an extensive literature review to determine whether the current psychopharmacological treatment recommendations required revision and whe...

journal_title：Schizophrenia bulletin

authors： Buchanan RW,Kreyenbuhl J,Kelly DL,Noel JM,Boggs DL,Fischer BA,Himelhoch S,Fang B,Peterson E,Aquino PR,Keller W,Schizophrenia Patient Outcomes Research Team (PORT).

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear what the best method is to allow people with schizophrenia to alter their cannabis intake. OBJECTIVES:To assess the effects of specific psychological...

journal_title：Schizophrenia bulletin

authors： Pushpa-Rajah JA,McLoughlin BC,Gillies D,Rathbone J,Variend H,Kalakouti E,Kyprianou K

更新日期：2015-03-01 00:00:00

abstract：:Despite NIMH efforts to facilitate the study of women and minorities in federally funded schizophrenia research, there is a significant lack of information about race differences in brain morphology and neuropsychological function in schizophrenia. A review of three major psychiatric journals between 1994 and 1996 rev...

journal_title：Schizophrenia bulletin

authors： Lewine RR,Caudle J

更新日期：1999-01-01 00:00:00

abstract：:Cognitive remediation is a behavioral intervention designed to improve cognition in people who have suffered a decline in neuropsychological functioning. The application of cognitive remediation for people with schizophrenia has become increasingly popular. In this article we attempt to determine what factors moderate...

journal_title：Schizophrenia bulletin

authors： Medalia A,Richardson R

更新日期：2005-10-01 00:00:00

abstract：:In 1917, Eugen Bleuler published an article (Mendelismus bei Psychosen, speziell bei der Schizophrenie [Mendelism in the Psychoses, especially Schizophrenia]) in response to the recently published first systematic family study of dementia praecox (DP) by Ernst Rüdin, then working under Kraepelin in Munich. Although br...

journal_title：Schizophrenia bulletin

authors： Kendler KS

更新日期：2020-07-08 00:00:00

abstract：:Little is known about the neurobiological factors that determine functional outcome in people at high risk for psychosis. We use multimodal neuroimaging to investigate whether cortical responses during a cognitive task and thalamic glutamate levels were associated with subsequent functional outcome. Sixty subjects par...

journal_title：Schizophrenia bulletin

authors： Allen P,Chaddock CA,Egerton A,Howes OD,Barker G,Bonoldi I,Fusar-Poli P,Murray R,McGuire P

更新日期：2015-03-01 00:00:00

abstract：:The psychometric high-risk strategy represents a useful methodologic adjunct to the traditional genetic high-risk research approach in the study of the etiology and development of schizophrenia. During the past 15 years, considerable research activity has focused on psychometrically identified individuals hypothesized...

journal_title：Schizophrenia bulletin

authors： Lenzenweger MF

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Emotion dysregulation is crucial to both poor social functioning and psychotic symptom formation in patients with schizophrenia. The efficient use of emotion regulation strategies, such as cognitive reappraisal, has been less frequently observed in the early phases of psychotic disorder. It is unknown whethe...

journal_title：Schizophrenia bulletin

authors： Kim M,Hwang WJ,Park J,Kim T,Oh S,Kwon JS

更新日期：2021-01-23 00:00:00

abstract：:This article focuses on the cross-modal reaction time paradigm, which has been used to study deviation patterns of shifting attention across stimulus modalities in schizophrenic patients. Cross-modal reaction time research involving pathological and nonpathological populations is reviewed. The influence of sex, stimul...

journal_title：Schizophrenia bulletin

authors： Mannuzza S

更新日期：1980-01-01 00:00:00

abstract：:While many who hear auditory hallucinations (AHs) experience them as unpleasant, some do not. Little is known about the correlates of AHs that are not unpleasant, or of the characteristics of those who hear them. To better understand this symptom, we used a comprehensive structured interview schedule to study 199 subj...

journal_title：Schizophrenia bulletin

authors： Copolov DL,Mackinnon A,Trauer T

更新日期：2004-01-01 00:00:00

abstract：:The goals of the project Social Cognition and Functioning in Schizophrenia (SCAF) were to (1) identify the domains to target from social neuroscience for translation to clinical schizophrenia research, (2) identify the paradigms that represent these domains for which the neural substrates are well documented, (3) adap...

journal_title：Schizophrenia bulletin

authors： Green MF,Penn DL

更新日期：2013-11-01 00:00:00

abstract：:Phenotypic heterogeneity within patients and controls may explain why the genetic variants contributing to schizophrenia risk explain only a fraction of the heritability. The aim of this study is to investigate quantitative and qualitative differences in psychosis symptoms in a sample including psychosis patients, the...

journal_title：Schizophrenia bulletin

authors： Derks EM,Allardyce J,Boks MP,Vermunt JK,Hijman R,Ophoff RA,GROUP.

更新日期：2012-05-01 00:00:00

abstract：:Since publication of the original Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations in 1998, considerable scientific advances have occurred in our knowledge about how to help persons with schizophrenia. Today an even stronger body of research supports the scientific basis of treatment. This...

journal_title：Schizophrenia bulletin

authors： Lehman AF,Kreyenbuhl J,Buchanan RW,Dickerson FB,Dixon LB,Goldberg R,Green-Paden LD,Tenhula WN,Boerescu D,Tek C,Sandson N,Steinwachs DM

更新日期：2004-01-01 00:00:00

abstract：:The dopamine hypothesis of schizophrenia is usually presented in a static, rather than dynamic fashion. We propose that increased dopaminergic activity may represent a stage of a dynamic schizophrenic process rather than its cause. Dopamine, as well as other neurotransmitters, responds in an adaptive fashion to stimul...

journal_title：Schizophrenia bulletin

authors： Csernansky JG,Holman CA,Hollister LE

更新日期：1983-01-01 00:00:00

abstract：:This study quantitatively examined reasons for substance use among individuals with psychotic disorders and explored the relationship of these reasons to substance use problems and dependence. Sixty-nine people with psychotic disorders were interviewed using a battery of questionnaires called the Substance Use Scale f...

journal_title：Schizophrenia bulletin

authors： Spencer C,Castle D,Michie PT

更新日期：2002-01-01 00:00:00

abstract：:The poverty and lack of social role in the lives of many people with schizophrenia seem similar to those of people in long-term unemployment, raising the possibility that there may be some commonalities in their time use and community functioning. To test this possibility, the social anxiety, time use, and activity pa...

journal_title：Schizophrenia bulletin

authors： Hayes RL,Halford WK

更新日期：1996-01-01 00:00:00

abstract：:Impaired attention is commonly observed among schizophrenia patients and those at genetic risk for the disease. This article reviews over 40 studies that used various versions of the Continuous Performance Test (CPT) as the primary measure of attention. These studies of normal subjects, affected patients, and various ...

journal_title：Schizophrenia bulletin

authors： Cornblatt BA,Keilp JG

更新日期：1994-01-01 00:00:00

abstract：:Patients with schizophrenia are severely impaired in crucial aspects of neurocognitive function. This impairment is the strongest clinical correlate of poor long-term outcome and adaptive dysfunction. Reports of neurocognitive enhancement with second generation antipsychotic medications have thus offered promise for i...

journal_title：Schizophrenia bulletin

authors： Keefe RS,Mohs RC,Bilder RM,Harvey PD,Green MF,Meltzer HY,Gold JM,Sano M

更新日期：2003-01-01 00:00:00

abstract：:Although there is recent evidence that cells from the peripheral immune system can gain access to the central nervous system in certain conditions such as multiple sclerosis, their role has not been assessed in psychosis. Here, we aimed to explore whether blood cell count was associated with brain volume and/or clinic...

journal_title：Schizophrenia bulletin

authors： Núñez C,Stephan-Otto C,Usall J,Bioque M,Lobo A,González-Pinto A,Pina-Camacho L,Vieta E,Castro-Fornieles J,Rodriguez-Jimenez R,Butjosa A,Janssen J,Cabrera B,Parellada M,Bernardo M,PEPs group.

更新日期：2019-06-18 00:00:00

abstract：:Psychotic-like experiences (PLEs) increase the risk of schizophrenia and other psychotic disorders yet are common in the community. Some PLEs, such as those associated with depression, distress, and poor functioning, may confer increased risk. The aim of this study is to determine the prevalence of PLEs in a nonpsycho...

journal_title：Schizophrenia bulletin

authors： Yung AR,Buckby JA,Cotton SM,Cosgrave EM,Killackey EJ,Stanford C,Godfrey K,McGorry PD

更新日期：2006-04-01 00:00:00

abstract：:In subjects at risk for psychosis, the studies on gray matter volume (GMV) predominantly reported volume loss compared with healthy controls (CON). However, other important morphological measurements such as cortical surface area (CSA) and cortical thickness (CT) were not systematically compared. So far, samples mostl...

journal_title：Schizophrenia bulletin

authors： Buechler R,Wotruba D,Michels L,Theodoridou A,Metzler S,Walitza S,Hänggi J,Kollias S,Rössler W,Heekeren K

更新日期：2020-12-01 00:00:00

abstract：:Schizophrenia (SZ) is a devastating mental disease caused by complex genetic and environmental factors. The pathological process and clinical manifestation of SZ are heterogeneous among patients, which hampers precise diagnosis and treatment of the disease. Since no objective marker for SZ has been established today, ...

journal_title：Schizophrenia bulletin

authors： Sun L,Yang X,Jiang J,Hu X,Qing Y,Wang D,Yang T,Yang C,Zhang J,Yang P,Wang P,Cai C,Wang J,He L,Wan C

更新日期：2018-06-06 00:00:00

abstract：BACKGROUND:Deficits in emotion processing are thought to underlie the key negative symptoms flat affect and anhedonia observed in psychotic disorders. This study investigated emotional experience and social behavior in the realm of daily life in a sample of patients with schizophrenia and schizoaffective disorder, stra...

journal_title：Schizophrenia bulletin

authors： Oorschot M,Lataster T,Thewissen V,Lardinois M,Wichers M,van Os J,Delespaul P,Myin-Germeys I

更新日期：2013-01-01 00:00:00

abstract：:Mobile assessment techniques have been used for nearly 3 decades in mental health research, including in investigations of individuals with schizophrenia and other severe disorders. This article reviews the benefits of these data collection strategies relative to traditional self-report or clinician-administered measu...

journal_title：Schizophrenia bulletin

authors： Kimhy D,Myin-Germeys I,Palmier-Claus J,Swendsen J

更新日期：2012-05-01 00:00:00