Motivations that maintain substance use among individuals with psychotic disorders.

Abstract:

:This study quantitatively examined reasons for substance use among individuals with psychotic disorders and explored the relationship of these reasons to substance use problems and dependence. Sixty-nine people with psychotic disorders were interviewed using a battery of questionnaires called the Substance Use Scale for Psychosis (SUSP). Symptoms and medication side effects were also measured. A factor analysis revealed similar motives for substance use (mostly alcohol and cannabis use) as in the general population: "enhancement," "social motives," "coping with unpleasant affect," and "conformity and acceptance." A fifth factor, "relief of positive symptoms and side effects," demonstrated limited reliability. "Coping" and "enhancement" motives were found to lead to substance use problems and dependence. Mediator analysis indicated that worse symptoms lead to stronger motives for substance use, which in turn lead to stronger psychological dependence on that substance. These findings have the potential to inform effective treatment for substance use in psychosis.

journal_name

Schizophr Bull

journal_title

Schizophrenia bulletin

authors

Spencer C,Castle D,Michie PT

doi

10.1093/oxfordjournals.schbul.a006934

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

233-47

issue

2

eissn

0586-7614

issn

1745-1701

journal_volume

28

pub_type

杂志文章
  • Cannabis and schizophrenia.

    abstract:BACKGROUND:Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear what the best method is to allow people with schizophrenia to alter their cannabis intake. OBJECTIVES:To assess the effects of specific psychological...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/sbu168

    authors: Pushpa-Rajah JA,McLoughlin BC,Gillies D,Rathbone J,Variend H,Kalakouti E,Kyprianou K

    更新日期:2015-03-01 00:00:00

  • Psychotherapy with persons suffering from schizophrenia: the need for a new agenda.

    abstract::The success of the biological revolution in our understanding of schizophrenia, along with the lack of convincing evidence for the efficacy of global approaches to individual psychotherapy with schizophrenia, has led to the virtual disappearance of research and theory in this area. However, it seems timely to reexamin...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/15.3.349

    authors: Coursey RD

    更新日期:1989-01-01 00:00:00

  • The Schizophrenia Care and Assessment Program Health Questionnaire (SCAP-HQ): an instrument to assess outcomes of schizophrenia care.

    abstract::Advances in treatment technologies and development of evidence-based standards of care demand better methods for routine assessment of outcomes for schizophrenia in systems of care. This article describes the development and psychometrics of a new instrument to assess outcomes of routine care for persons with schizoph...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007001

    authors: Lehman AF,Fischer EP,Postrado L,Delahanty J,Johnstone BM,Russo PA,Crown WH

    更新日期:2003-01-01 00:00:00

  • Distress attributed to negative symptoms in schizophrenia.

    abstract::The purpose of the study was to examine (1) to which negative symptoms schizophrenia patients attribute distress and (2) whether clinical variables can predict the levels of reported distress. With the help of a research assistant, 86 hospitalized patients completed a self-rating scale for negative symptoms. The 21 it...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033490

    authors: Selten JP,Wiersma D,van den Bosch RJ

    更新日期:2000-01-01 00:00:00

  • Disorders of thought are severe mood disorders: the selective attention defect in mania challenges the Kraepelinian dichotomy a review.

    abstract::Kraepelin said severe mental illness was due to 2 diseases subsequently characterized as disorders of thought vs disorders of mood, ie, the Kraepelinian dichotomy. Schizophrenia, traditionally considered the disorder of thought, has been defined by the presence of hallucinations, delusions, catatonia, and disorganizat...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/sbm035

    authors: Raymond Lake C

    更新日期:2008-01-01 00:00:00

  • Psychosis as a disorder of reduced cathectic capacity: Freud's analysis of the Schreber case revisited.

    abstract::Approximately 100 years ago, a prominent German public figure name Daniel Schreber wrote memoirs of his experiences in asylums. His case was diagnosed Dementia Praecox at times and Paranoia at others by his treaters. Freud analyzed Schreber's memoirs from the perspective of his "libido" theory of developmentally organ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/sbp019

    authors: McGlashan TH

    更新日期:2009-05-01 00:00:00

  • Elevated Striatal Dopamine Function in Immigrants and Their Children: A Risk Mechanism for Psychosis.

    abstract::Migration is a major risk factor for schizophrenia but the neurochemical processes involved are unknown. One candidate mechanism is through elevations in striatal dopamine synthesis and release. The objective of this research was to determine whether striatal dopamine function is elevated in immigrants compared to non...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/sbw181

    authors: Egerton A,Howes OD,Houle S,McKenzie K,Valmaggia LR,Bagby MR,Tseng HH,Bloomfield MA,Kenk M,Bhattacharyya S,Suridjan I,Chaddock CA,Winton-Brown TT,Allen P,Rusjan P,Remington G,Meyer-Lindenberg A,McGuire PK,Mizrahi R

    更新日期:2017-03-01 00:00:00

  • Positive vs. negative schizophrenia: a critical evaluation.

    abstract::Discussion of the positive vs. negative distinction often fails to address whether this distinction refers to symptoms, syndromes, or diseases. Symptoms and syndromes are etiologically nonspecific, while diseases have a specific identifiable pathophysiology or etiology. The positive vs. negative distinction is sometim...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/11.3.380

    authors: Andreasen NC

    更新日期:1985-01-01 00:00:00

  • Effectiveness of integrated psychological therapy (IPT) for schizophrenia patients: a research update.

    abstract::Standardized recovery criteria go beyond symptom remission and put special emphasis on personal and social functioning in residence, work, and leisure. Against this background, evidence-based integrated approaches combining cognitive remediation with social skills therapy show promise for improving functional recovery...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/schbul/sbr072

    authors: Roder V,Mueller DR,Schmidt SJ

    更新日期:2011-09-01 00:00:00

  • Interventions to Address Medical Conditions and Health-Risk Behaviors Among Persons With Serious Mental Illness: A Comprehensive Review.

    abstract::People with serious mental illness (SMI) have mortality rates 2 to 3 times higher than the overall US population, largely due to cardiovascular disease. The prevalence of cardiovascular risk factors such as obesity and diabetes mellitus and other conditions, such as HIV/AIDS, is heightened in this group. Based on the ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/sbv101

    authors: McGinty EE,Baller J,Azrin ST,Juliano-Bult D,Daumit GL

    更新日期:2016-01-01 00:00:00

  • Early brain wiring: activity-dependent processes.

    abstract::One of the leading theories of the neuropathology of schizophrenia is that it is a developmental disorder of "neural connectivity." To assess this theory, it is first necessary to understand how precise neural connections normally are established. Sensory-driven neural activity has been widely recognized as crucial fo...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a006880

    authors: Penn AA

    更新日期:2001-01-01 00:00:00

  • Overview and summary: twenty-five-year followup of high-risk children.

    abstract::We report a 25-year followup of a group of 50 children at genetic risk for schizophrenia (by virtue of having a parent with the disorder) and 50 matched controls. The children who eventually developed schizophrenia spectrum disorders, including schizophrenia, were identifiable by cognitive-psychophysiological, neuroin...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/21.2.227

    authors: Mirsky AF,Kugelmass S,Ingraham LJ,Frenkel E,Nathan M

    更新日期:1995-01-01 00:00:00

  • Antipsychotic prescribing practices in the Veterans Healthcare Administration--New York metropolitan region.

    abstract::Most research literature concerning pharmacological treatments reports results from controlled clinical trials, which provide data critical to assess the efficacy of new treatments in research populations. Fewer studies examine how treatments are adopted in everyday practice settings, where comorbid disorders and envi...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006924

    authors: Weissman EM

    更新日期:2002-01-01 00:00:00

  • "Real world" atypical antipsychotic prescribing practices in public child and adolescent inpatient settings.

    abstract::This article examines the factors that influence antipsychotic use among youth treated in public inpatient facilities. By combining data from 11 focus groups, a survey of 43 researchers and clinicians, and a chart review of 100 closed patient charts, we investigated the interplay between physicians' and staff members'...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006913

    authors: Pappadopulos E,Jensen PS,Schur SB,MacIntyre JC 2nd,Ketner S,Van Orden K,Sverd J,Sardana S,Woodlock D,Schweitzer R,Rube D

    更新日期:2002-01-01 00:00:00

  • Antipsychotics: Past and Future: National Institute of Mental Health Division of Services and Intervention Research Workshop, July 14, 1998.

    abstract::A workshop on "Antipsychotics: Past and Future" was convened by the National Institute of Mental Health (NIMH), Division of Services and Intervention Research (DSIR), on July 14, 1998, to review the results of recent antipsychotic drug research, discuss current standards of treatment, and identify areas needing furthe...

    journal_title:Schizophrenia bulletin

    pub_type:

    doi:10.1093/oxfordjournals.schbul.a033387

    authors: Dawkins K,Lieberman JA,Lebowitz BD,Hsiao JK

    更新日期:1999-01-01 00:00:00

  • Schizophrenia and multiple sclerosis.

    abstract::Similarities in clinical course, age of onset, geographical distribution, and immunological responses of patients with schizophrenia and multiple sclerosis (MS) suggest that these two common illnesses of young adults may belong to a similar class of disorders. This review examines some of the similarities and differen...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/14.2.231

    authors: Stevens JR

    更新日期:1988-01-01 00:00:00

  • What is schizophrenia?

    abstract::One of the main questions related to schizophrenia is, naturally enough, what is it? Such a question may seem obvious, naive, impossible, or any combination of these. And certainly it is a bit demanding to expect that anyone could say what schizophrenia is in 1,000 words. On the other hand, we felt that it was worth t...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/8.3.433

    authors: Meltzer HY,Liberman RP

    更新日期:1982-01-01 00:00:00

  • How families evaluate mental health professionals, resources, and effects of illness.

    abstract::Evaluations by families (of chronically mentally ill individuals) of mental health professionals and resources were solicited through a mail survey. The respondents, largely better educated, white, and female, indicated a generally high level of dissatisfaction. Emotional support, information, and aftercare resources ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/8.4.626

    authors: Holden DF,Lewine RR

    更新日期:1982-01-01 00:00:00

  • Disruptions of Sleep/Wake Patterns in the Stable Tubule Only Polypeptide (STOP) Null Mouse Model of Schizophrenia.

    abstract::Disruption of sleep/wake cycles is common in patients with schizophrenia and correlates with cognitive and affective abnormalities. Mice deficient in stable tubule only polypeptide (STOP) show cognitive, behavioral, and neurobiological deficits that resemble those seen in patients with schizophrenia, but little is kno...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/sbw017

    authors: Profitt MF,Deurveilher S,Robertson GS,Rusak B,Semba K

    更新日期:2016-09-01 00:00:00

  • Reassessing "Praecox Feeling" in Diagnostic Decision Making in Schizophrenia: A Critical Review.

    abstract::The "Praecox Feeling" (PF) is a classical concept referring to a characteristic feeling of bizarreness experienced by a psychiatrist while encountering a person with schizophrenia. Although the PF used to be considered a core symptom of the schizophrenia spectrum, it fell into disuse since the spread of operationalize...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/sby172

    authors: Gozé T,Moskalewicz M,Schwartz MA,Naudin J,Micoulaud-Franchi JA,Cermolacce M

    更新日期:2019-09-11 00:00:00

  • Neurocognitive correlates of schizotypy in first degree relatives of schizophrenia patients.

    abstract::We examined neurocognitive correlates of three dimensions of schizotypy in 63 healthy first degree relatives of schizophrenia patients. Neurocognitive measures of attention, verbal memory, and prefrontal functioning were combined with self-report and interview measures of schizotypy. State-psychopathology (anxiety and...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006946

    authors: Vollema MG,Postma B

    更新日期:2002-01-01 00:00:00

  • Comorbid Major Depressive Disorder in Schizophrenia: A Systematic Review and Meta-Analysis.

    abstract::Comorbid major depressive disorder (MDD) in schizophrenia (SZ; SZ-MDD) has been identified as a major prognostic factor. However, the prevalence and associated factors of SZ-MDD have never been explored in a meta-analysis. All studies assessing the prevalence of SZ-MDD in stabilized outpatients with a standardized sca...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/sbaa153

    authors: Etchecopar-Etchart D,Korchia T,Loundou A,Llorca PM,Auquier P,Lançon C,Boyer L,Fond G

    更新日期:2020-11-30 00:00:00

  • Rejecting the patient: preliminary validation of a self-report scale.

    abstract::The authors describe an easily administered scale being developed to assess the rejecting feelings of family respondents toward former mental patients who return to live with their families. Based upon a sample of 133 discharged mental patients and family members, the scale demonstrates a moderately high reliability (...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/5.2.220

    authors: Kreisman DE,Simmens SJ,Joy VD

    更新日期:1979-01-01 00:00:00

  • Structured Interview for Assessing Perceptual Anomalies (SIAPA).

    abstract::Clinical descriptions of perceptual and attentional anomalies in schizophrenia emphasize phenomena such as flooding, or inundation, by sensory stimuli. A failure of sensory "gating" mechanisms in the brain is hypothesized to account for these symptoms, and this hypothesis has led to a marked interest in their putative...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033402

    authors: Bunney WE Jr,Hetrick WP,Bunney BG,Patterson JV,Jin Y,Potkin SG,Sandman CA

    更新日期:1999-01-01 00:00:00

  • Cognitive Subtyping in Schizophrenia: A Latent Profile Analysis.

    abstract::Cognitive dysfunction is a core feature of schizophrenia. The subtyping of cognitive performance in schizophrenia may aid the refinement of disease heterogeneity. The literature on cognitive subtyping in schizophrenia, however, is limited by variable methodologies and neuropsychological tasks, lack of validation, and ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/schbul/sbaa157

    authors: Lim K,Smucny J,Barch DM,Lam M,Keefe RSE,Lee J

    更新日期:2020-10-24 00:00:00

  • The Potential of Cannabidiol Treatment for Cannabis Users With Recent-Onset Psychosis.

    abstract::A major factor associated with poor prognostic outcome after a first psychotic break is cannabis misuse, which is prevalent in schizophrenia and particularly common in individuals with recent-onset psychosis. Behavioral interventions aimed at reducing cannabis use have been unsuccessful in this population. Cannabidiol...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/sbx105

    authors: Hahn B

    更新日期:2018-01-13 00:00:00

  • Cognitive-behavioral therapy for medication-resistant symptoms.

    abstract::Cognitive-behavioral therapy for psychosis is described. It draws on the cognitive models and therapy approach of Beck and colleagues, combined with an application of stress-vulnerability models of schizophrenia and cognitive models of psychotic symptoms. There is encouraging evidence for the efficacy of this approach...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a033447

    authors: Garety PA,Fowler D,Kuipers E

    更新日期:2000-01-01 00:00:00

  • Improvements in negative symptoms and functional outcome after a new generation cognitive remediation program: a randomized controlled trial.

    abstract::Cognitive remediation improves cognition in patients with schizophrenia, but its effect on other relevant factors such as negative symptoms and functional outcome has not been extensively studied. In this hospital-based study, 84 inpatients with chronic schizophrenia were recruited from Alava Hospital (Spain). All of ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/schbul/sbt057

    authors: Sánchez P,Peña J,Bengoetxea E,Ojeda N,Elizagárate E,Ezcurra J,Gutiérrez M

    更新日期:2014-05-01 00:00:00

  • Brain Biomarkers of Vulnerability and Progression to Psychosis.

    abstract::Identifying predictors and elucidating the fundamental mechanisms underlying onset of psychosis are critical for the development of targeted preemptive interventions. This article presents a selective review of findings on risk prediction algorithms and potential mechanisms of onset in youth at clinical high-risk for ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/schbul/sbv173

    authors: Cannon TD

    更新日期:2016-07-01 00:00:00

  • A meta-analysis of mentalizing impairments in adults with schizophrenia and autism spectrum disorder.

    abstract::Mentalizing has been examined both in autism spectrum disorder (ASD) and schizophrenia (SCZ) primarily by either cognitive-linguistic (referred to as verbal) or emotion recognition from eyes (referred to as visual) mentalizing tasks. Each type of task is thought to measure different aspects of mentalizing. Differences...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,meta分析

    doi:10.1093/schbul/sbt048

    authors: Chung YS,Barch D,Strube M

    更新日期:2014-05-01 00:00:00