Effectiveness of integrated psychological therapy (IPT) for schizophrenia patients: a research update.

abstract：:Spatial working memory (WM) processing has 3 distinct phases: encoding, maintenance, and retrieval and its dysfunction is a core feature in schizophrenia. We examined phase-specific brain activations associated with spatial WM in first-degree relatives of schizophrenia (genetic high risk, GHR), ultra-high risk (UHR) s...

journal_title：Schizophrenia bulletin

authors： Choi JS,Park JY,Jung MH,Jang JH,Kang DH,Jung WH,Han JY,Choi CH,Hong KS,Kwon JS

更新日期：2012-11-01 00:00:00

abstract：Background:Motor abnormalities (MAs) of severe mental disorders have been traditionally neglected both in clinical practice and research, although they are an increasing focus of attention because of their clinical and neurobiological relevance. For historical reasons, most of the literature on MAs has been focused to ...

journal_title：Schizophrenia bulletin

authors： Peralta V,Cuesta MJ

更新日期：2017-09-01 00:00:00

abstract：:Negative and positive symptoms were investigated in a sample of 72 young schizophrenic and depressed patients at followup approximately 1 1/2 years after hospital discharge. Flat affect, poverty of speech, and psychomotor retardation were included as negative symptoms, and delusions, hallucinations, and florid thought...

journal_title：Schizophrenia bulletin

authors： Pogue-Geile MF,Harrow M

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Patients with deficit schizophrenia differ from nondeficit patients with schizophrenia relative to several neurobiological correlates and relative to the risk factors of family history and season of birth. Exposure to human herpesviruses is a possible risk factor for schizophrenia. We hypothesized that there...

journal_title：Schizophrenia bulletin

authors： Dickerson F,Kirkpatrick B,Boronow J,Stallings C,Origoni A,Yolken R

更新日期：2006-04-01 00:00:00

abstract：:The prevalence and demographic and clinical correlates of lifetime substance use disorders were examined in a cohort of 325 recently hospitalized psychiatric patients (53% schizophrenia or schizoaffective disorder). Alcohol use was the most common type of substance use disorder, followed by cannabis and cocaine use. U...

journal_title：Schizophrenia bulletin

authors： Mueser KT,Yarnold PR,Rosenberg SD,Swett C Jr,Miles KM,Hill D

更新日期：2000-01-01 00:00:00

abstract：:The apparent neglect of neuropsychologic deficits in schizophrenia as the basis for therapeutic intervention, together with only isolated attempts at remediating them, probably reflect the nature of impairments, the functional significance of which is uncertain. A critique of the limitations inherent in the appealing ...

journal_title：Schizophrenia bulletin

authors： Hogarty GE,Flesher S

更新日期：1992-01-01 00:00:00

abstract：:Aerobic exercise has been shown to improve symptoms in multiepisode schizophrenia, including cognitive impairments, but results are inconsistent. Therefore, we evaluated the effects of an enriched environment paradigm consisting of bicycle ergometer training and add-on computer-assisted cognitive remediation (CACR) tr...

journal_title：Schizophrenia bulletin

authors： Malchow B,Keller K,Hasan A,Dörfler S,Schneider-Axmann T,Hillmer-Vogel U,Honer WG,Schulze TG,Niklas A,Wobrock T,Schmitt A,Falkai P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:In light of the evidence for brain white matter (WM) abnormalities in schizophrenia, study of normal WM maturation in adolescence may provide critical insights relevant to the neurodevelopment of the disorder. Voxel-wise diffusion tensor imaging (DTI) studies have consistently demonstrated increases in fract...

journal_title：Schizophrenia bulletin

authors： Peters BD,Szeszko PR,Radua J,Ikuta T,Gruner P,DeRosse P,Zhang JP,Giorgio A,Qiu D,Tapert SF,Brauer J,Asato MR,Khong PL,James AC,Gallego JA,Malhotra AK

更新日期：2012-11-01 00:00:00

abstract：:Recent studies provide considerable evidence that schizophrenia and bipolar disorder may share overlapping etiologic determinants. Identifying disease-related genetic effects is a major focus in schizophrenia and bipolar disorder research, with implications for clarifying diagnosis and developing specific treatments f...

journal_title：Schizophrenia bulletin

authors： Thaker G

更新日期：2008-07-01 00:00:00

abstract：:Cognitive models of interpersonal problem solving have been proposed for, but infrequently tested on, samples of schizophrenia subjects. This study undertook to examine the relationships between the receiving, processing, and sending skills that comprise one model of interpersonal problem solving with information proc...

journal_title：Schizophrenia bulletin

authors： Corrigan PW,Toomey R

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Cannabis use is associated with a younger age at onset of psychosis, an indicator of poor prognosis, but better cognitive function, a positive prognostic indicator. We aimed to clarify the role of age at onset and cognition on outcomes in cannabis users with first-episode schizophrenia as well as the effect o...

journal_title：Schizophrenia bulletin

authors： Leeson VC,Harrison I,Ron MA,Barnes TR,Joyce EM

更新日期：2012-06-01 00:00:00

abstract：:Family studies of schizophrenia frequently include relatives of schizophrenia probands with diagnoses falling within the schizophrenia spectrum. As part of an ongoing genetic linkage study of schizophrenia, the authors examined case material from 50 relatives (of schizophrenia probands) who received a DSM-III-R diagno...

journal_title：Schizophrenia bulletin

authors： Gladis MM,Levinson DF,Mowry BJ

更新日期：1994-01-01 00:00:00

abstract：:Family interventions for first-episode psychosis (FEP) are an integral component of treatment, with positive effects mainly on patients' mental state and relapse rate. However, comparatively little attention has been paid to the effects of family interventions on caregivers' stress coping and well-being, especially in...

journal_title：Schizophrenia bulletin

authors： Chien WT,Thompson DR,Lubman DI,McCann TV

更新日期：2016-11-01 00:00:00

abstract：:This study compared the performance of 39 biological relatives of persons with schizophrenia to that of 30 normal adult controls on graphesthesia processing, a complex somatosensory processing task. The relatives performed significantly worse on the graphesthesia task compared to the healthy controls. The relatives an...

journal_title：Schizophrenia bulletin

authors： Chang BP,Lenzenweger MF

更新日期：2004-01-01 00:00:00

abstract：:Genome-wide association studies (GWASs) have identified >100 susceptibility loci for schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by numerous genetic variants but with small effect size. We conducted a GWAS in the Japanese (JPN) population (a) to detect novel SCZ-susceptibility gene...

journal_title：Schizophrenia bulletin

authors： Ikeda M,Takahashi A,Kamatani Y,Momozawa Y,Saito T,Kondo K,Shimasaki A,Kawase K,Sakusabe T,Iwayama Y,Toyota T,Wakuda T,Kikuchi M,Kanahara N,Yamamori H,Yasuda Y,Watanabe Y,Hoya S,Aleksic B,Kushima I,Arai H,Takaki

更新日期：2019-06-18 00:00:00

abstract：UNLABELLED:Early intervention is assumed to improve outcome in first-episode psychosis, but this has not been proven. OBJECTIVE:To study whether 1-year outcome will be better in a health care sector with early detection (ED) of psychosis compared with sectors with no early detection (no-ED). DESIGN:A quasi-experiment...

journal_title：Schizophrenia bulletin

authors： Larsen TK,Melle I,Auestad B,Friis S,Haahr U,Johannessen JO,Opjordsmoen S,Rund BR,Simonsen E,Vaglum P,McGlashan T

更新日期：2006-10-01 00:00:00

abstract：:Given the variety of "organic" or "toxic" conditions that may produce, precipitate, or exacerbate psychotic disorders, it is important to attempt to clarify existing nosologies and to highlight the need for research strategies that may help to validate relevant distinctions. This review provides a brief discussion of ...

journal_title：Schizophrenia bulletin

authors： Kane JM,Selzer J

更新日期：1991-01-01 00:00:00

abstract：:Although the various manifestations of disordered thought have played a central role in diagnostic and theoretical considerations of schizophrenia, such symptoms have not been found specific to schizophrenia, and at best have shown weak relations to outcome. As part of a 7-year followup study of a sample of young, acu...

journal_title：Schizophrenia bulletin

authors： Knight RA,Elliott DS,Roff JD,Watson CG

更新日期：1986-01-01 00:00:00

abstract：:Social networks of 35 mentally ill persons were studied in Lao villages. Mental illness was associated with a decrease in size of social networks, disproportionate reliance on family, and asymmetric instrumental exchange. Nonkin "sponsors" provided assistance to those alienated from or abandoned by relatives. For thos...

journal_title：Schizophrenia bulletin

authors： Westermeyer J,Pattison EM

更新日期：1981-01-01 00:00:00

abstract：:Cognitive Enhancement Therapy (CET) is a developmental approach to the rehabilitation of schizophrenia patients that attempts to facilitate an abstracting and "gistful" social cognition as a compensatory alternative to the more demanding and controlled cognitive strategies that often characterize schizophrenia as well...

journal_title：Schizophrenia bulletin

authors： Hogarty GE,Flesher S

更新日期：1999-01-01 00:00:00

abstract：:Persons with schizophrenia have a reduced life expectancy largely due to death from natural causes. Factors that have been previously associated with excess mortality include cigarette smoking and antipsychotic medication. The role of other environmental factors such as exposure to infectious agents has been the subje...

journal_title：Schizophrenia bulletin

authors： Dickerson F,Stallings C,Origoni A,Schroeder J,Khushalani S,Yolken R

更新日期：2014-07-01 00:00:00

abstract：:Ventricle-to-brain ratio (VBR) was measured from the computed tomographic (CT) scans of 33 very recent-onset psychotic patients. Illness severity and positive and negative symptoms were also assessed in 21 of these patients with schizophreniform disorder. Forty-five neurology patients served as controls. Analyses reve...

journal_title：Schizophrenia bulletin

authors： Holsenbeck LS 3rd,Davidson LM,Hostetter RE,Casanova MF,Taylor DO,Kelley CT,Perrotta C Jr,Borison RL,Diamond B

更新日期：1992-01-01 00:00:00

abstract：:The purpose of this study was to assess how neurocognition and social cognition were associated with initial functional level and with rates of functional change in intensive community-based psychosocial rehabilitation interventions that have been shown to yield significant functional change for individuals diagnosed ...

journal_title：Schizophrenia bulletin

authors： Brekke JS,Hoe M,Long J,Green MF

更新日期：2007-09-01 00:00:00

abstract：:The prodrome of psychosis has become a target for early identification and for treatments that address both symptoms and risk for future psychosis. Interest and activity in this realm is now worldwide. Clinical trials with rigorous methodology have only just begun, making treatment guidelines premature. Despite the sp...

journal_title：Schizophrenia bulletin

authors： McGlashan TH,Addington J,Cannon T,Heinimaa M,McGorry P,O'Brien M,Penn D,Perkins D,Salokangas RK,Walsh B,Woods SW,Yung A

更新日期：2007-05-01 00:00:00

abstract：:This study investigated the role of reasoning biases in delusion formation and maintenance. Reasoning judgments have been shown to be influenced by prior knowledge, beliefs, and experience--that is, information stored in semantic memory. It was hypothesized that high schizotypes would exhibit a "jump to conclusions" s...

journal_title：Schizophrenia bulletin

authors： Sellen JL,Oaksford M,Gray NS

更新日期：2005-01-01 00:00:00

abstract：:Methodological issues involved in assessing the prevalence of substance abuse in schizophrenia are discussed, and previous research in this area is comprehensively reviewed. Many studies suffer from methodological shortcomings, including the lack of diagnostic rigor, adequate sample sizes, and simultaneous assessment ...

journal_title：Schizophrenia bulletin

authors： Mueser KT,Yarnold PR,Levinson DF,Singh H,Bellack AS,Kee K,Morrison RL,Yadalam KG

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Embodied emotions arise from interoceptive and somatosensory processes, and are essential to the development of a stable sense of self. Emotional embodiment is therefore inherently interwoven with our sense of bodily self-awareness, and allows us to navigate complex social situations. Given that the core feat...

journal_title：Schizophrenia bulletin

authors： Torregrossa LJ,Snodgress MA,Hong SJ,Nichols HS,Glerean E,Nummenmaa L,Park S

更新日期：2019-09-11 00:00:00

abstract：:Psychiatric research, including the search for predisposing genes, has tended to proceed under the assumptions that schizophrenia and bipolar disorder, as defined in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and International Statistical Classification of Diseases, 10th Revision, are discr...

journal_title：Schizophrenia bulletin

authors： Owen MJ,Craddock N,Jablensky A

更新日期：2007-07-01 00:00:00

abstract：:Cognitive disruption in schizophrenia is associated with altered patterns of spatiotemporal interaction associated with multiple electroencephalogram (EEG) frequency bands in cortex. In particular, changes in the generation of gamma (30-80 Hz) and beta2 (20-29 Hz) rhythms correlate with observed deficits in communicat...

journal_title：Schizophrenia bulletin

authors： Roopun AK,Cunningham MO,Racca C,Alter K,Traub RD,Whittington MA

更新日期：2008-09-01 00:00:00

abstract：:The study describes the Cardiff Anomalous Perceptions Scale (CAPS), a new validated measure of perceptual anomalies. The 32-item CAPS measure is a reliable, self-report scale, which uses neutral language, demonstrates high content validity, and includes subscales that measure distress, intrusiveness, and frequency of ...

journal_title：Schizophrenia bulletin

authors： Bell V,Halligan PW,Ellis HD

更新日期：2006-04-01 00:00:00