Recruitment and treatment practices for help-seeking "prodromal" patients.

abstract：BACKGROUND:Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear what the best method is to allow people with schizophrenia to alter their cannabis intake. OBJECTIVES:To assess the effects of specific psychological...

journal_title：Schizophrenia bulletin

authors： Pushpa-Rajah JA,McLoughlin BC,Gillies D,Rathbone J,Variend H,Kalakouti E,Kyprianou K

更新日期：2015-03-01 00:00:00

abstract：:The aim of the study was to evaluate the latent structure of DSM-IV schizotypal personality disorder (SPD) diagnostic criteria. The sample consisted of 564 consecutively admitted inpatients and outpatients. Exploratory latent class analysis identified a four-class model as the best fitting model for DSM-IV SPD criteri...

journal_title：Schizophrenia bulletin

authors： Fossati A,Maffei C,Battaglia M,Bagnato M,Donati D,Donini M,Fiorilli M,Novella L

更新日期：2001-01-01 00:00:00

abstract：:The current study sought to examine the underlying brain changes in individuals with high schizotypy by integrating networks derived from brain structural and functional imaging. Individuals with high schizotypy (n = 35) and low schizotypy (n = 34) controls were screened using the Schizotypal Personality Questionnaire...

journal_title：Schizophrenia bulletin

authors： Wang Y,Yan C,Yin DZ,Fan MX,Cheung EF,Pantelis C,Chan RC

更新日期：2015-03-01 00:00:00

abstract：:This analysis examines the notion of progressive deterioration in schizophrenia, using long-term followup data on hospital episodes in defined cohorts from psychiatric case registers in Victoria, Australia; Denmark; and Salford, England. The analyses differentiate heterogeneity existing at the first hospitalization fo...

journal_title：Schizophrenia bulletin

authors： Eaton WW,Bilker W,Haro JM,Herrman H,Mortensen PB,Freeman H,Burgess P

更新日期：1992-01-01 00:00:00

abstract：:While previous studies have found an increased incidence of schizophrenia in some immigrant groups, differences in age of onset in these groups has not been examined. The purpose of this study was to compare age of first hospitalization of (1) native-born people versus immigrants, (2) immigrants from different countri...

journal_title：Schizophrenia bulletin

authors： Rabinowitz J,Fennig S

更新日期：2002-01-01 00:00:00

abstract：:Since publication of the original Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations in 1998, considerable scientific advances have occurred in our knowledge about how to help persons with schizophrenia. Today an even stronger body of research supports the scientific basis of treatment. This...

journal_title：Schizophrenia bulletin

authors： Lehman AF,Kreyenbuhl J,Buchanan RW,Dickerson FB,Dixon LB,Goldberg R,Green-Paden LD,Tenhula WN,Boerescu D,Tek C,Sandson N,Steinwachs DM

更新日期：2004-01-01 00:00:00

abstract：:Antistigma campaigns have been promoting a medical view of schizophrenia. Given the growing body of research finding negative associations between biogenetic (BG) causal attributions and stigmatizing attitudes, this approach must be reappraised. The present study investigates the impact of different psychoeducational ...

journal_title：Schizophrenia bulletin

authors： Lincoln TM,Arens E,Berger C,Rief W

更新日期：2008-09-01 00:00:00

abstract：:In this issue we have tried to bring together a series of reviews describing new developments in the pharmacologic management of schizophrenia. Important progress is being made not only in medication development, but also in furthering our ability to use available treatments and treatment combinations in the most effe...

journal_title：Schizophrenia bulletin

authors： Kane JM

更新日期：1991-01-01 00:00:00

abstract：UNLABELLED:We aimed to discover whether metabolic complications of schizophrenia (SZ) are present in first episode (FE) and unmedicated (UM) patients, in comparison with patients established on antipsychotic medication (AP). METHOD:A systematic search, critical appraisal, and meta-analysis were conducted of studies to...

journal_title：Schizophrenia bulletin

authors： Mitchell AJ,Vancampfort D,De Herdt A,Yu W,De Hert M

更新日期：2013-03-01 00:00:00

abstract：Objective:A proinflammatory imbalance in the tumor necrosis factor (TNF) system may contribute to the pathogenesis of schizophrenia (SCZ) and bipolar disorders (BDs) and related comorbidities. We investigated the relative distribution of TNF-related molecules in blood and dorsolateral prefrontal cortex (DLPFC) in these...

journal_title：Schizophrenia bulletin

authors： Hoseth EZ,Ueland T,Dieset I,Birnbaum R,Shin JH,Kleinman JE,Hyde TM,Mørch RH,Hope S,Lekva T,Abraityte AJ,Michelsen AE,Melle I,Westlye LT,Ueland T,Djurovic S,Aukrust P,Weinberger DR,Andreassen OA

更新日期：2017-07-01 00:00:00

abstract：:As part of an open clinical trial currently underway at the Max Planck Institute of Psychiatry in Munich, the feasibility of behavioral family management (Falloon et al. 1984) for schizophrenia in combination with two different neuroleptic medication strategies was investigated. The treatment approaches were psychoedu...

journal_title：Schizophrenia bulletin

authors： Wiedemann G,Hahlweg K,Hank G,Feinstein E,Müller U,Dose M

更新日期：1994-01-01 00:00:00

abstract：:Although schizophrenia affects a number of brain regions and produces a range of clinical symptoms, we believe its origins lie at the level of single neurons and simple networks. Owing to this, as well as to its high degree of heritability, we hypothesize that schizophrenia is amenable to cell-based studies in vitro. ...

journal_title：Schizophrenia bulletin

authors： Tran NN,Ladran IG,Brennand KJ

更新日期：2013-01-01 00:00:00

abstract：:Advances in treatment technologies and development of evidence-based standards of care demand better methods for routine assessment of outcomes for schizophrenia in systems of care. This article describes the development and psychometrics of a new instrument to assess outcomes of routine care for persons with schizoph...

journal_title：Schizophrenia bulletin

authors： Lehman AF,Fischer EP,Postrado L,Delahanty J,Johnstone BM,Russo PA,Crown WH

更新日期：2003-01-01 00:00:00

abstract：:Persistent negative symptoms represent an alternative approach for assessing negative symptoms in the context of clinical trials. Persistent negative symptoms are designed to capture those symptoms that lead to functional impairment but are currently understudied and for which there are no currently available effectiv...

journal_title：Schizophrenia bulletin

authors： Buchanan RW

更新日期：2007-07-01 00:00:00

abstract：:Increasing awareness of the importance of neurocognitive impairments in schizophrenia has fostered considerable interest in the prospects for cognitive rehabilitation. Nevertheless, optimism has outpaced progress. We first review recent literature on the central assumptions that underlie cognitive rehabilitation, incl...

journal_title：Schizophrenia bulletin

authors： Bellack AS,Gold JM,Buchanan RW

更新日期：1999-01-01 00:00:00

abstract：:Psychotic-like experiences (PLEs) increase the risk of schizophrenia and other psychotic disorders yet are common in the community. Some PLEs, such as those associated with depression, distress, and poor functioning, may confer increased risk. The aim of this study is to determine the prevalence of PLEs in a nonpsycho...

journal_title：Schizophrenia bulletin

authors： Yung AR,Buckby JA,Cotton SM,Cosgrave EM,Killackey EJ,Stanford C,Godfrey K,McGorry PD

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Over the past 30 years, illness management programs and cognitive-behavioral therapy for psychosis have gained prominence in the treatment of schizophrenia. However, little is known about the long-term benefits of these types of programs when delivered during inpatient treatment following a symptom exacerbati...

journal_title：Schizophrenia bulletin

authors： Schaub A,Mueser KT,von Werder T,Engel R,Möller HJ,Falkai P

更新日期：2016-07-01 00:00:00

abstract：:Recent years have witnessed widespread interest in the early phase of schizophrenia and other psychotic disorders. Strategies have been introduced to attempt to identify individuals in the prepsychotic or prodromal phase. The most widely used of these approaches is the ultra-high risk (UHR) approach, which combines kn...

journal_title：Schizophrenia bulletin

authors： Nelson B,Yung AR,Bechdolf A,McGorry PD

更新日期：2008-03-01 00:00:00

abstract：Objective:Evidence suggests that social skills training (SST) is an efficacious intervention for negative symptoms in psychosis, whereas evidence of efficacy in other psychosis symptom domains is limited. The current article reports a comprehensive meta-analytic review of the evidence for SST across relevant outcome me...

journal_title：Schizophrenia bulletin

authors： Turner DT,McGlanaghy E,Cuijpers P,van der Gaag M,Karyotaki E,MacBeth A

更新日期：2018-04-06 00:00:00

abstract：:Little is known about the neurobiological factors that determine functional outcome in people at high risk for psychosis. We use multimodal neuroimaging to investigate whether cortical responses during a cognitive task and thalamic glutamate levels were associated with subsequent functional outcome. Sixty subjects par...

journal_title：Schizophrenia bulletin

authors： Allen P,Chaddock CA,Egerton A,Howes OD,Barker G,Bonoldi I,Fusar-Poli P,Murray R,McGuire P

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Adult patients having schizophrenia (SZ) or bipolar disorder (BP) may have in common neurocognitive deficits. Former evidence suggests impairments in several neuropsychological functions in young offspring at genetic risk for SZ or BP. Moreover, a dose-response relation may exist between the degree of famili...

journal_title：Schizophrenia bulletin

authors： Maziade M,Rouleau N,Gingras N,Boutin P,Paradis ME,Jomphe V,Boutin J,Létourneau K,Gilbert E,Lefebvre AA,Doré MC,Marino C,Battaglia M,Mérette C,Roy MA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Working memory (WM) deficit is a key feature of schizophrenia that relates to a generalized neural inefficiency of extensive brain areas. To date, it remains unknown how these distributed regions are systemically organized at the connectome level and how the disruption of such organization brings about the W...

journal_title：Schizophrenia bulletin

authors： Yang J,Pu W,Wu G,Chen E,Lee E,Liu Z,Palaniyappan L

更新日期：2020-07-08 00:00:00

abstract：:Traditional psychiatric treatment approaches have not been very successful with the "revolving door patient." A variety of findings suggest that the social network, as opposed to the individual patient, may be a more viable locus for intervention. A conceptual review and analysis of the literature reveals two construc...

journal_title：Schizophrenia bulletin

authors： Morin RC,Seidman E

更新日期：1986-01-01 00:00:00

abstract：:The original CHoice of Outcome In Cbt for psychosEs (CHOICE) measure was designed in collaboration with experts by experience as a patient-reported "Psychological Recovery" outcome measure for cognitive-behavioral therapy for psychosis (CBTp). A short version (CHOICE-SF) was developed to use as a brief outcome measure...

journal_title：Schizophrenia bulletin

authors： Webb R,Bartl G,James B,Skan R,Peters E,Jones AM,Garety P,Kuipers E,Hayward M,Greenwood K

更新日期：2020-11-20 00:00:00

abstract：:North American outcome studies of schizophrenia conducted within the past quarter century are reviewed if their minimum average followup is 10 years and they meet at least some modern design criteria. Ten such investigations are described and summarized. Taken as a whole, they demonstrate that schizophrenia can be a c...

journal_title：Schizophrenia bulletin

authors： McGlashan TH

更新日期：1988-01-01 00:00:00

abstract：:Strong familial aggregation of schizophrenia has been reported but there is uncertainty concerning the degree of genetic contribution to the phenotypic variance of the disease. This study aimed to examine the familial aggregation and heritability of schizophrenia, and the relative risks (RRs) of other psychiatric dise...

journal_title：Schizophrenia bulletin

authors： Chou IJ,Kuo CF,Huang YS,Grainge MJ,Valdes AM,See LC,Yu KH,Luo SF,Huang LS,Tseng WY,Zhang W,Doherty M

更新日期：2017-09-01 00:00:00

abstract：:A number of psychosocial treatments are available for persons with schizophrenia that include social skills training, cognitive behavioral therapy, cognitive remediation, and social cognition training. These treatments are reviewed and discussed in terms of how they address key components of functional recovery such a...

journal_title：Schizophrenia bulletin

authors： Kern RS,Glynn SM,Horan WP,Marder SR

更新日期：2009-03-01 00:00:00

abstract：:The demand for information by relatives and the success of family intervention programs with an initial didactic component has resulted in a proliferation of educational interventions in schizophrenia. The present study assesses the impact of a single educational session on relatives of recent-onset schizophrenic pati...

journal_title：Schizophrenia bulletin

authors： Cozolino LJ,Goldstein MJ,Nuechterlein KH,West KL,Snyder KS

更新日期：1988-01-01 00:00:00

abstract：Background:The diagnostic and prognostic significance of the DSM-5-defined Attenuated Psychosis Syndrome (DSM-5-APS) in individuals undergoing an ultra high risk (UHR) clinical assessment for suspicion of psychosis risk is unknown. Methods:Prospective cohort study including all consecutive help-seeking individuals und...

journal_title：Schizophrenia bulletin

authors： Fusar-Poli P,De Micheli A,Cappucciati M,Rutigliano G,Davies C,Ramella-Cravaro V,Oliver D,Bonoldi I,Rocchetti M,Gavaghan L,Patel R,McGuire P

更新日期：2018-02-15 00:00:00

abstract：:People with serious mental illness (SMI) have mortality rates 2 to 3 times higher than the overall US population, largely due to cardiovascular disease. The prevalence of cardiovascular risk factors such as obesity and diabetes mellitus and other conditions, such as HIV/AIDS, is heightened in this group. Based on the ...

journal_title：Schizophrenia bulletin

authors： McGinty EE,Baller J,Azrin ST,Juliano-Bult D,Daumit GL

更新日期：2016-01-01 00:00:00