Abstract:
:Given the variety of "organic" or "toxic" conditions that may produce, precipitate, or exacerbate psychotic disorders, it is important to attempt to clarify existing nosologies and to highlight the need for research strategies that may help to validate relevant distinctions. This review provides a brief discussion of some of those issues.
journal_name
Schizophr Bulljournal_title
Schizophrenia bulletinauthors
Kane JM,Selzer Jdoi
10.1093/schbul/17.1.69subject
Has Abstractpub_date
1991-01-01 00:00:00pages
69-73issue
1eissn
0586-7614issn
1745-1701journal_volume
17pub_type
杂志文章,评审abstract::We reported previously that residents of Greater Helsinki, Finland, whose mothers were exposed to the 1957 influenza epidemic during their second trimester of gestation had a significantly elevated risk of developing adult schizophrenia. The majority of the replication studies to date have not determined whether the m...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/20.2.263
更新日期:1994-01-01 00:00:00
abstract::Most research literature concerning pharmacological treatments reports results from controlled clinical trials, which provide data critical to assess the efficacy of new treatments in research populations. Fewer studies examine how treatments are adopted in everyday practice settings, where comorbid disorders and envi...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/oxfordjournals.schbul.a006924
更新日期:2002-01-01 00:00:00
abstract::The association between low birth weight and schizophrenia has been suggested by many studies. Small for gestational age (SGA) is a measure used as a proxy for intrauterine growth restriction. We aim to examine if children who are born SGA are at increased risk of developing schizophrenia and whether an association ma...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbs148
更新日期:2013-11-01 00:00:00
abstract::Genetic factors are known to influence both risk for schizophrenia (SZ) and variation in brain structure. A pressing question is whether the genetic underpinnings of brain phenotype and the disorder overlap. Using multivariate analytic methods and focusing on 1,402 common single-nucleotide polymorphisms (SNPs) mapped ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sby010
更新日期:2019-01-01 00:00:00
abstract::A pilot study of the effects of metacognition-oriented social skills training (MOSST) on social functioning in patients with schizophrenia spectrum disorders (SSDs) reported promising results. The main purpose of the current trial was to compare the effectiveness and potential benefits of MOSST vs conventional social ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章,随机对照试验
doi:10.1093/schbul/sbx168
更新日期:2018-10-17 00:00:00
abstract::Comorbid major depressive disorder (MDD) in schizophrenia (SZ; SZ-MDD) has been identified as a major prognostic factor. However, the prevalence and associated factors of SZ-MDD have never been explored in a meta-analysis. All studies assessing the prevalence of SZ-MDD in stabilized outpatients with a standardized sca...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbaa153
更新日期:2020-11-30 00:00:00
abstract::Increased latency of stimulus encoding is presented as a central deficit in schizophrenia cognition. Encoding, here, entails the internal representation of presenting stimuli in a format facilitating their implementation in other cognitive processes, such as those taking place in working memory. Historical roots of su...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章,评审
doi:10.1093/schbul/sbm056
更新日期:2007-07-01 00:00:00
abstract::Antistigma campaigns have been promoting a medical view of schizophrenia. Given the growing body of research finding negative associations between biogenetic (BG) causal attributions and stigmatizing attitudes, this approach must be reappraised. The present study investigates the impact of different psychoeducational ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbm131
更新日期:2008-09-01 00:00:00
abstract::Schizotypal disorder is characterized by odd behavior and attenuated forms of schizophrenic features without the manifestation of overt and sustained psychoses. Past studies suggest that schizotypal disorder shares biological and psychological commonalties with schizophrenia. Structural magnetic resonance imaging (MRI...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbz051
更新日期:2020-02-26 00:00:00
abstract::In a sample of 75 women recruited from the community, we measured trauma/maltreatment history and symptoms of schizotypal personality disorder, using both questionnaire and interview measures. As hypothesized, individuals with histories of trauma/maltreatment had elevated levels of schizotypal symptoms. Among types of...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/oxfordjournals.schbul.a006985
更新日期:2003-01-01 00:00:00
abstract:UNLABELLED:We aimed to discover whether metabolic complications of schizophrenia (SZ) are present in first episode (FE) and unmedicated (UM) patients, in comparison with patients established on antipsychotic medication (AP). METHOD:A systematic search, critical appraisal, and meta-analysis were conducted of studies to...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章,meta分析,评审
doi:10.1093/schbul/sbs082
更新日期:2013-03-01 00:00:00
abstract::Staff members from nine mental health agencies were trained in psychiatric rehabilitation technology. The trainers then received intensive followup to assist them in implementing the technology in their own agencies. Evaluation of the impact of the "training of trainers" strategy suggested that mental health workers w...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/12.4.709
更新日期:1986-01-01 00:00:00
abstract::The purpose of this study was to assess how neurocognition and social cognition were associated with initial functional level and with rates of functional change in intensive community-based psychosocial rehabilitation interventions that have been shown to yield significant functional change for individuals diagnosed ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章,多中心研究
doi:10.1093/schbul/sbl072
更新日期:2007-09-01 00:00:00
abstract::Phenomenological research suggests that pure manic and depressive states are less common than mixtures of the two and that the two poles of mood are characterized by opposite ways of experiencing time. In mania, the subjective experience of time is sped up and in depression it is slowed down, perhaps reflecting differ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbl061
更新日期:2007-01-01 00:00:00
abstract::Negative and positive symptoms were investigated in a sample of 72 young schizophrenic and depressed patients at followup approximately 1 1/2 years after hospital discharge. Flat affect, poverty of speech, and psychomotor retardation were included as negative symptoms, and delusions, hallucinations, and florid thought...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/10.3.371
更新日期:1984-01-01 00:00:00
abstract::The evidence suggesting that genetic factors are involved in the etiology of schizophrenia is reviewed. Despite methodological and other difficulties, independent lines of research--family, twin, and adoption studies--point in a common direction: Persons genetically at risk for schizophrenia are more likely to become ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章,评审
doi:10.1093/schbul/6.3.404
更新日期:1980-01-01 00:00:00
abstract:INTRODUCTION:Abnormalities in the neurophysiological measures P300 amplitude and latency constitute endophenotypes for psychosis. Disrupted-in-Schizophrenia-1 (DISC1) has been proposed as a promising susceptibility gene for schizophrenia, and a previous study has suggested that it is associated with P300 deficits in sc...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbr101
更新日期:2013-01-01 00:00:00
abstract:Objective:A proinflammatory imbalance in the tumor necrosis factor (TNF) system may contribute to the pathogenesis of schizophrenia (SCZ) and bipolar disorders (BDs) and related comorbidities. We investigated the relative distribution of TNF-related molecules in blood and dorsolateral prefrontal cortex (DLPFC) in these...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbw183
更新日期:2017-07-01 00:00:00
abstract::The multilevel control of eye movements for the researcher in the schizophrenic disease process includes the saccadic trajectory, the dual mode tracking system, and schematically directed eye movements in fixation, in scanpaths, and other looking strategies, and in reading. Coordination of eye movements with head move...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/9.1.55
更新日期:1983-01-01 00:00:00
abstract::Secondary sources continue to cite a one-page preliminary note about the Michigan State Psychotherapy Project, ignoring fuller reports in print. Relevant experience and training are critical to quality control of psychotherapy in schizophrenia research. This investigation is unique in that "experienced" meant that the...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/4.4.480
更新日期:1978-01-01 00:00:00
abstract::This study examined the content of subscales within a multidimensional scale of self-reported schizotypy and their subsequent interrelationship by means of confirmatory factor analysis (CFA). Neither single-factor nor four-factor models provided good fits to the data; two-factor and three-factor models showed very goo...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/oxfordjournals.schbul.a033480
更新日期:2000-01-01 00:00:00
abstract::Recent advances in functional genomics have facilitated the identification of multiple genes and isoforms associated with the genetic risk of schizophrenia, yet the causal variations remain largely unclear. A previous study reported that the schizophrenia risk single-nucleotide polymorphism (SNP) rs7085104 at 10q24.32...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbaa098
更新日期:2021-01-23 00:00:00
abstract::Disrupted thalamo-cortical connectivity is regarded as a core psychopathology in patients diagnosed with schizophrenia. However, whether the thalamo-cortical white matter connectivity is disrupted before the onset of psychosis is still unknown. To determine this gap in knowledge, the strength of thalamo-cortical white...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbv169
更新日期:2016-05-01 00:00:00
abstract::The clinical importance of subtypes based on enduring deficit or negative symptoms was examined in a group of schizophrenic patients who were assessed twice over a 1-year period. Subgroups of patients with high levels of enduring negative or deficit symptoms, based on the Scale for the Assessment of Negative Symptoms ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/17.4.565
更新日期:1991-01-01 00:00:00
abstract::This research studied hypotheses that positive thought disorder in schizophrenia is influenced by patients' not taking in immediate target contextual material, thereby losing vital cues that guide thought processes. We assessed 164 acute inpatients (including 55 schizophrenia and 31 bipolar disorder patients), using s...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/oxfordjournals.schbul.a033502
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Cannabis use has been identified as a potent predictor of the earlier onset of psychosis, but meta-analysis has not indicated that it has a clear effect in established psychosis. AIM:To assess the association between cannabis and outcomes, including whether change in cannabis use affects symptoms and functi...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章,随机对照试验
doi:10.1093/schbul/sbr152
更新日期:2013-03-01 00:00:00
abstract::The author reviews a number of studies which have shown that the overall mortality among patients with schizophrenia is about twice that in the general population. The highest excess mortality is found in suicide and violent death, but there seems to be an increased mortality also in cardiovascular disorders. Whether ...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/15.1.81
更新日期:1989-01-01 00:00:00
abstract::Negative symptoms of schizophrenia remain an area of substantial unmet clinical need. By convening a consensus conference in January 2005, the NIMH has taken a leading role in stimulating a resurgence of interest in methodological considerations related to development of new medications for treating negative symptoms....
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbj056
更新日期:2006-04-01 00:00:00
abstract::Psychobiological research in child psychiatry requires rigorous assessment of behavior and multiple perspectives on brain function through neurochemical, neuroendocrine, psychophysiological, and other advanced methods. The serious neuropsychiatric disorders of childhood, such as autism, attention deficit disorder, and...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/8.2.205
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Cigarette smoking was consistently found to be more prevalent in individuals with schizophrenia than in other psychiatric groups and the general population. These findings have been interpreted as evidence of a specific association between schizophrenia and smoking. However, the supporting data come primaril...
journal_title:Schizophrenia bulletin
pub_type: 杂志文章
doi:10.1093/schbul/sbn066
更新日期:2010-01-01 00:00:00