Mobile assessment guide for research in schizophrenia and severe mental disorders.

abstract：OBJECTIVE:Both neurocognitive impairments and a history of childhood abuse are highly prevalent in patients with schizophrenia. Childhood trauma has been associated with memory impairment as well as hippocampal volume reduction in adult survivors. The aim of the following study was to examine the contribution of childh...

journal_title：Schizophrenia bulletin

authors： Shannon C,Douse K,McCusker C,Feeney L,Barrett S,Mulholland C

更新日期：2011-05-01 00:00:00

abstract：:The deficit syndrome is thought to characterize a pathophysiologically distinct subgroup of patients with schizophrenia. Supporting this notion, prior research examining the neuropsychological correlates of the deficit syndrome has suggested the presence of a differential impairment in frontal and parietal functions. ...

journal_title：Schizophrenia bulletin

authors： Cohen AS,Saperstein AM,Gold JM,Kirkpatrick B,Carpenter WT Jr,Buchanan RW

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To investigate patterns of mental health service and antipsychotic use following a first-episode schizophrenia (FES) and to examine the role of the treatment setting in which individuals are first diagnosed. METHOD:Analysis of de-identified administrative claims data from the OptumLabs Data Warehouse was use...

journal_title：Schizophrenia bulletin

authors： Gilmer TP,van der Ven E,Susser E,Dixon LB,Olfson M

更新日期：2020-01-04 00:00:00

abstract：:Over the past 20 years, there has been a relatively quiet but persistent effort to investigate anatomical neuropathology in schizophrenia. This effort has involved post-mortem histopathology using novel preparation procedures, pneumoencephalography, and computed tomography. The bulk of this research is critically revi...

journal_title：Schizophrenia bulletin

authors： Weinberger DR,Wagner RL,Wyatt RJ

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Similar to patients with other chronic disorders, patients with serious mental illness (SMI) are often poorly adherent with prescribed medications. OBJECTIVE:We conducted a randomized controlled trial examining the effectiveness of a pharmacy-based intervention (Meds-Help) in increasing antipsychotic medica...

journal_title：Schizophrenia bulletin

authors： Valenstein M,Kavanagh J,Lee T,Reilly P,Dalack GW,Grabowski J,Smelson D,Ronis DL,Ganoczy D,Woltmann E,Metreger T,Wolschon P,Jensen A,Poddig B,Blow FC

更新日期：2011-07-01 00:00:00

abstract：:Schizophrenia affects people of all age groups. Treatment plans for older adults with schizophrenia must consider the effects of age on the course of the illness as well as on the response to antipsychotics and to psychosocial interventions. Positive symptoms of schizophrenia tend to become less severe, substance abus...

journal_title：Schizophrenia bulletin

authors： Jeste DV,Maglione JE

更新日期：2013-09-01 00:00:00

abstract：:Data provided by case managers in community support programs are used to analyze the problems of families providing shelter to mentally ill relatives. Factors affecting complaints in 345 family households are contrasted with factors leading to complaints in a subsample of 622 other residential alternatives. Behavioral...

journal_title：Schizophrenia bulletin

authors： Gubman GD,Tessler RC,Willis G

更新日期：1987-01-01 00:00:00

abstract：:Although glutamate was first hypothesized to be involved in the pathophysiology of schizophrenia in the 1980s, it was the demonstration that N-methyl-D-aspartate (NMDA) receptor antagonists, the dissociative anesthetics, could replicate the full range of psychotic, negative, cognitive, and physiologic features of schi...

journal_title：Schizophrenia bulletin

authors： Coyle JT

更新日期：2012-09-01 00:00:00

abstract：:We studied schizophrenia spectrum disorders in Chernobyl accident survivors by analyzing Chernobyl exclusion zone (EZ) archives (1986-1997) and by conducting a psychophysiological examination of 100 patients with acute radiation sickness (ARS) and 100 workers of the Chernobyl EZ who had worked as "liquidators-voluntee...

journal_title：Schizophrenia bulletin

authors： Loganovsky KN,Loganovskaja TK

更新日期：2000-01-01 00:00:00

abstract：:Cognitive remediation improves cognition in patients with schizophrenia, but its effect on other relevant factors such as negative symptoms and functional outcome has not been extensively studied. In this hospital-based study, 84 inpatients with chronic schizophrenia were recruited from Alava Hospital (Spain). All of ...

journal_title：Schizophrenia bulletin

authors： Sánchez P,Peña J,Bengoetxea E,Ojeda N,Elizagárate E,Ezcurra J,Gutiérrez M

更新日期：2014-05-01 00:00:00

abstract：:The left superior temporal sulcus (STS) plays an important role in integrating audiovisual information and is functionally connected to disparate regions of the brain. For the integration of gesture information in an abstract sentence context (metaphoric gestures), intact connectivity between the left STS and the infe...

journal_title：Schizophrenia bulletin

authors： Straube B,Green A,Sass K,Kircher T

更新日期：2014-07-01 00:00:00

abstract：:This study examined the course of illness and factors affecting it in schizophrenias with onset between the ages of 14 and 18. Noteworthy in comparison to findings from other followup studies is the higher proportion of chronic courses of illness, about 50 percent. In addition, the type of course of illness correspond...

journal_title：Schizophrenia bulletin

authors： Krausz M,Müller-Thomsen T

更新日期：1993-01-01 00:00:00

abstract：:The aim of the study was to evaluate the latent structure of DSM-IV schizotypal personality disorder (SPD) diagnostic criteria. The sample consisted of 564 consecutively admitted inpatients and outpatients. Exploratory latent class analysis identified a four-class model as the best fitting model for DSM-IV SPD criteri...

journal_title：Schizophrenia bulletin

authors： Fossati A,Maffei C,Battaglia M,Bagnato M,Donati D,Donini M,Fiorilli M,Novella L

更新日期：2001-01-01 00:00:00

abstract：:People with serious mental illness (SMI) have mortality rates 2 to 3 times higher than the overall US population, largely due to cardiovascular disease. The prevalence of cardiovascular risk factors such as obesity and diabetes mellitus and other conditions, such as HIV/AIDS, is heightened in this group. Based on the ...

journal_title：Schizophrenia bulletin

authors： McGinty EE,Baller J,Azrin ST,Juliano-Bult D,Daumit GL

更新日期：2016-01-01 00:00:00

abstract：:Kraepelin said severe mental illness was due to 2 diseases subsequently characterized as disorders of thought vs disorders of mood, ie, the Kraepelinian dichotomy. Schizophrenia, traditionally considered the disorder of thought, has been defined by the presence of hallucinations, delusions, catatonia, and disorganizat...

journal_title：Schizophrenia bulletin

authors： Raymond Lake C

更新日期：2008-01-01 00:00:00

abstract：:The normal developmental series of brains in the Yakovlev Collection has been examined to explore the possibility that various brain regions implicated in schizophrenia may show changes in myelination during late adolescence, a period coinciding with the appearance of early symptoms of this disorder. The prefrontal, c...

journal_title：Schizophrenia bulletin

authors： Benes FM

更新日期：1989-01-01 00:00:00

abstract：:The traditional view of life events is that the crucial factor is the number which occur within a defined time period. This was examined as part of a 2-year, prospective, longitudinal study of prospective, longitudinal study of 518 people, each of whom was interviewed every 6 months with Holmes and Rahe's Recent LIfe ...

journal_title：Schizophrenia bulletin

authors： Streiner DL,Norman GR,McFarlane AH,Roy RG

更新日期：1981-01-01 00:00:00

abstract：:We found diurnal weight gain to be abnormal among 93 chronically psychotic patients, most of whom had schizophrenia. They were weighed at 7 a.m. and 4 p.m. weekly for 3 weeks. We normalized the diurnal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the differenc...

journal_title：Schizophrenia bulletin

authors： Vieweg WV,Godleski LS,Graham P,Kellogg EJ,Goldman F,Barber J,Bayliss EV,Glick JL,Hundley PL,Yank GR

更新日期：1989-01-01 00:00:00

abstract：:Increased critical stimulus duration among nonpsychotic subjects with Minnesota Multiphasic Personality Inventory 2-7-8 profiles in the Merritt and Balogh letter-discrimination procedure is consistent with the view that this abnormality might be a vulnerability indicator for a poor prognosis, chronic type of schizophr...

journal_title：Schizophrenia bulletin

authors： Nuechterlein KH,Dawson ME

更新日期：1985-01-01 00:00:00

abstract：:In a prospective study involving 161 patients discharged from inpatient psychiatric treatment, outcome data were obtained for 93 percent of the patients 1 year after clinic discharge. Sixty-seven percent of the patients were directly interviewed for the followup examination. Outcome data for symptomatology, relapses, ...

journal_title：Schizophrenia bulletin

authors： Pietzcker A,Gaebel W

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:ABT-288 is a highly potent histamine-3 receptor antagonist that has demonstrated pro-cognitive effects in preclinical models relevant to schizophrenia. This study evaluated the efficacy and safety of two doses of ABT-288 in the treatment of cognitive impairment associated with schizophrenia. METHODS:A ran...

journal_title：Schizophrenia bulletin

authors： Haig GM,Bain E,Robieson W,Othman AA,Baker J,Lenz RA

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:Embodied emotions arise from interoceptive and somatosensory processes, and are essential to the development of a stable sense of self. Emotional embodiment is therefore inherently interwoven with our sense of bodily self-awareness, and allows us to navigate complex social situations. Given that the core feat...

journal_title：Schizophrenia bulletin

authors： Torregrossa LJ,Snodgress MA,Hong SJ,Nichols HS,Glerean E,Nummenmaa L,Park S

更新日期：2019-09-11 00:00:00

abstract：:The demand for information by relatives and the success of family intervention programs with an initial didactic component has resulted in a proliferation of educational interventions in schizophrenia. The present study assesses the impact of a single educational session on relatives of recent-onset schizophrenic pati...

journal_title：Schizophrenia bulletin

authors： Cozolino LJ,Goldstein MJ,Nuechterlein KH,West KL,Snyder KS

更新日期：1988-01-01 00:00:00

abstract：:Patients with schizophrenia are severely impaired in crucial aspects of neurocognitive function. This impairment is the strongest clinical correlate of poor long-term outcome and adaptive dysfunction. Reports of neurocognitive enhancement with second generation antipsychotic medications have thus offered promise for i...

journal_title：Schizophrenia bulletin

authors： Keefe RS,Mohs RC,Bilder RM,Harvey PD,Green MF,Meltzer HY,Gold JM,Sano M

更新日期：2003-01-01 00:00:00

abstract：:Social cognitive impairments and negative symptoms are core features of schizophrenia closely associated with impaired community functioning. However, little is known about whether these are independent dimensions of illness and if so, whether individuals with schizophrenia can be meaningfully classified based on thes...

journal_title：Schizophrenia bulletin

authors： Bell MD,Corbera S,Johannesen JK,Fiszdon JM,Wexler BE

更新日期：2013-01-01 00:00:00

abstract：:This article examines the factors that influence antipsychotic use among youth treated in public inpatient facilities. By combining data from 11 focus groups, a survey of 43 researchers and clinicians, and a chart review of 100 closed patient charts, we investigated the interplay between physicians' and staff members'...

journal_title：Schizophrenia bulletin

authors： Pappadopulos E,Jensen PS,Schur SB,MacIntyre JC 2nd,Ketner S,Van Orden K,Sverd J,Sardana S,Woodlock D,Schweitzer R,Rube D

更新日期：2002-01-01 00:00:00

abstract：:The causal mechanism underlying the well-established relation between advancing paternal age and schizophrenia is hypothesized to involve mutational errors during spermatogenesis that occur with increasing frequency as males age. Point mutations are well known to increase with advancing paternal age while other errors...

journal_title：Schizophrenia bulletin

authors： Perrin MC,Brown AS,Malaspina D

更新日期：2007-11-01 00:00:00

abstract：:Medical geology is the application of trace element geography to epidemiology. This approach is used to compare the geographic distribution of selenium and other trace elements in soil and food with that of high schizophrenia rates in the United States and other countries. Since the comparison is most statistically si...

journal_title：Schizophrenia bulletin

authors： Brown JS Jr

更新日期：1994-01-01 00:00:00

abstract：:This cross-sectional study examined the relationships between neurocognitive and social functioning in a sample of 80 outpatients with DSM-III-R schizophrenia. The neurocognitive battery included measures of verbal ability, verbal memory, visual memory, executive functioning, visual-spatial organization, vigilance, an...

journal_title：Schizophrenia bulletin

authors： Addington J,Addington D

更新日期：1999-01-01 00:00:00

abstract：:To understand the biological significance of a decreased platelet MAO activity in schizophrenia, it is important to answer many questions about the basic molecular properties of the enzyme. The past decade has witnessed a huge expansion of research in this area which has provided some of these answers. A wide variety ...

journal_title：Schizophrenia bulletin

authors： Edwards DJ

更新日期：1980-01-01 00:00:00