Quality of life events and their relationship to strain.

abstract：BACKGROUND:Adult patients having schizophrenia (SZ) or bipolar disorder (BP) may have in common neurocognitive deficits. Former evidence suggests impairments in several neuropsychological functions in young offspring at genetic risk for SZ or BP. Moreover, a dose-response relation may exist between the degree of famili...

journal_title：Schizophrenia bulletin

authors： Maziade M,Rouleau N,Gingras N,Boutin P,Paradis ME,Jomphe V,Boutin J,Létourneau K,Gilbert E,Lefebvre AA,Doré MC,Marino C,Battaglia M,Mérette C,Roy MA

更新日期：2009-09-01 00:00:00

abstract：:Research on the effectiveness of short-term education programs in changing societal attitudes about mental illness has been mixed. Education efforts seem to be mediated by characteristics of the program participants. This study determines whether the effects of a specially prepared, semester-long course on severe ment...

journal_title：Schizophrenia bulletin

authors： Holmes EP,Corrigan PW,Williams P,Canar J,Kubiak MA

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Given the evidence that reasoning biases contribute to delusional persistence and change, several research groups have made systematic efforts to modify them. The current experiment tested the hypothesis that targeting reasoning biases would result in change in delusions. METHODS:One hundred and one partici...

journal_title：Schizophrenia bulletin

authors： Garety P,Waller H,Emsley R,Jolley S,Kuipers E,Bebbington P,Dunn G,Fowler D,Hardy A,Freeman D

更新日期：2015-03-01 00:00:00

abstract：:Recent studies provide considerable evidence that schizophrenia and bipolar disorder may share overlapping etiologic determinants. Identifying disease-related genetic effects is a major focus in schizophrenia and bipolar disorder research, with implications for clarifying diagnosis and developing specific treatments f...

journal_title：Schizophrenia bulletin

authors： Thaker G

更新日期：2008-07-01 00:00:00

abstract：:To better characterize hippocampal pathophysiology in schizophrenia, we conducted a longitudinal study evaluating hippocampal functional connectivity during resting state, using seeds prescribed in its anterior and posterior regions. We enrolled 34 unmedicated patients with schizophrenia or schizoaffective disorder (S...

journal_title：Schizophrenia bulletin

authors： Kraguljac NV,White DM,Hadley N,Hadley JA,Ver Hoef L,Davis E,Lahti AC

更新日期：2016-07-01 00:00:00

abstract：:We reported previously that residents of Greater Helsinki, Finland, whose mothers were exposed to the 1957 influenza epidemic during their second trimester of gestation had a significantly elevated risk of developing adult schizophrenia. The majority of the replication studies to date have not determined whether the m...

journal_title：Schizophrenia bulletin

authors： Mednick SA,Huttunen MO,Machón RA

更新日期：1994-01-01 00:00:00

abstract：:Because negative symptoms, including motivational deficits, are a critical unmet need in schizophrenia, there are many ongoing efforts to develop new pharmacological and psychosocial interventions for these impairments. A common challenge of these studies involves how to evaluate and select optimal endpoints. Currentl...

journal_title：Schizophrenia bulletin

authors： Green MF,Horan WP,Barch DM,Gold JM

更新日期：2015-09-01 00:00:00

abstract：:Comorbid major depressive disorder (MDD) in schizophrenia (SZ; SZ-MDD) has been identified as a major prognostic factor. However, the prevalence and associated factors of SZ-MDD have never been explored in a meta-analysis. All studies assessing the prevalence of SZ-MDD in stabilized outpatients with a standardized sca...

journal_title：Schizophrenia bulletin

authors： Etchecopar-Etchart D,Korchia T,Loundou A,Llorca PM,Auquier P,Lançon C,Boyer L,Fond G

更新日期：2020-11-30 00:00:00

abstract：:This cross-sectional study examined the relationships between neurocognitive and social functioning in a sample of 80 outpatients with DSM-III-R schizophrenia. The neurocognitive battery included measures of verbal ability, verbal memory, visual memory, executive functioning, visual-spatial organization, vigilance, an...

journal_title：Schizophrenia bulletin

authors： Addington J,Addington D

更新日期：1999-01-01 00:00:00

abstract：:Psychiatric research, including the search for predisposing genes, has tended to proceed under the assumptions that schizophrenia and bipolar disorder, as defined in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and International Statistical Classification of Diseases, 10th Revision, are discr...

journal_title：Schizophrenia bulletin

authors： Owen MJ,Craddock N,Jablensky A

更新日期：2007-07-01 00:00:00

abstract：:The prevalence and demographic and clinical correlates of lifetime substance use disorders were examined in a cohort of 325 recently hospitalized psychiatric patients (53% schizophrenia or schizoaffective disorder). Alcohol use was the most common type of substance use disorder, followed by cannabis and cocaine use. U...

journal_title：Schizophrenia bulletin

authors： Mueser KT,Yarnold PR,Rosenberg SD,Swett C Jr,Miles KM,Hill D

更新日期：2000-01-01 00:00:00

abstract：Objective:Evidence suggests that social skills training (SST) is an efficacious intervention for negative symptoms in psychosis, whereas evidence of efficacy in other psychosis symptom domains is limited. The current article reports a comprehensive meta-analytic review of the evidence for SST across relevant outcome me...

journal_title：Schizophrenia bulletin

authors： Turner DT,McGlanaghy E,Cuijpers P,van der Gaag M,Karyotaki E,MacBeth A

更新日期：2018-04-06 00:00:00

abstract：:Between 5% and 10% of people with psychosis will die by suicide, a rate which is 20-75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals of psychotic experiences and negative metacognitive beliefs about losing menta...

journal_title：Schizophrenia bulletin

authors： Hutton P,Di Rienzo F,Turkington D,Spencer H,Taylor P

更新日期：2019-01-01 00:00:00

abstract：:In subjects at risk for psychosis, the studies on gray matter volume (GMV) predominantly reported volume loss compared with healthy controls (CON). However, other important morphological measurements such as cortical surface area (CSA) and cortical thickness (CT) were not systematically compared. So far, samples mostl...

journal_title：Schizophrenia bulletin

authors： Buechler R,Wotruba D,Michels L,Theodoridou A,Metzler S,Walitza S,Hänggi J,Kollias S,Rössler W,Heekeren K

更新日期：2020-12-01 00:00:00

abstract：:The European Psychiatric Services: Inputs Linked to Outcomes and Needs (EPSILON) study was a EU BIOMED-2-funded comparative, cross-national, cross-sectional study aimed (1) to produce standardized versions of five key research instruments in five languages, and (2) to compare the characteristics, needs, and life quali...

journal_title：Schizophrenia bulletin

authors： van Wijngaarden B,Schene A,Koeter M,Becker T,Knapp M,Knudsen HC,Tansella M,Thornicroft G,Vázquez-Barquero JL,Lasalvia A,Leese M,EPSILON Study Group.

更新日期：2003-01-01 00:00:00

abstract：:Advances in treatment technologies and development of evidence-based standards of care demand better methods for routine assessment of outcomes for schizophrenia in systems of care. This article describes the development and psychometrics of a new instrument to assess outcomes of routine care for persons with schizoph...

journal_title：Schizophrenia bulletin

authors： Lehman AF,Fischer EP,Postrado L,Delahanty J,Johnstone BM,Russo PA,Crown WH

更新日期：2003-01-01 00:00:00

abstract：:In 1917, Eugen Bleuler published an article (Mendelismus bei Psychosen, speziell bei der Schizophrenie [Mendelism in the Psychoses, especially Schizophrenia]) in response to the recently published first systematic family study of dementia praecox (DP) by Ernst Rüdin, then working under Kraepelin in Munich. Although br...

journal_title：Schizophrenia bulletin

authors： Kendler KS

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:Executive control of attention in schizophrenia has recently been assessed by means of the Attention Network Test (ANT). In the past, for tasks assessing executive attention, findings in schizophrenia have been contradictory, among others suggesting a lack of increased stimulus interference effects. Attentio...

journal_title：Schizophrenia bulletin

authors： Opgen-Rhein C,Neuhaus AH,Urbanek C,Hahn E,Sander T,Dettling M

更新日期：2008-11-01 00:00:00

abstract：:A substantial amount of research has focused on the midbrain dopamine system and its role in emotional and motivational behaviors. In diseases in which dopamine function is compromised, patients exhibit a constellation of symptoms, suggesting that the dopamine system plays an important role in the integration of sever...

journal_title：Schizophrenia bulletin

authors： Haber SN,Fudge JL

更新日期：1997-01-01 00:00:00

abstract：:Development of schizophrenia relates to both genetic and environmental factors. Functional deficits in many cognitive domains, including the ability to communicate in social interactions and impaired recognition of facial expressions, are common for patients with schizophrenia and might also be present in individuals ...

journal_title：Schizophrenia bulletin

authors： Lieslehto J,Kiviniemi VJ,Nordström T,Barnett JH,Murray GK,Jones PB,Paus T,Veijola J

更新日期：2019-06-18 00:00:00

abstract：:Phenomenological research suggests that pure manic and depressive states are less common than mixtures of the two and that the two poles of mood are characterized by opposite ways of experiencing time. In mania, the subjective experience of time is sped up and in depression it is slowed down, perhaps reflecting differ...

journal_title：Schizophrenia bulletin

authors： Ghaemi SN

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Emotion dysregulation is crucial to both poor social functioning and psychotic symptom formation in patients with schizophrenia. The efficient use of emotion regulation strategies, such as cognitive reappraisal, has been less frequently observed in the early phases of psychotic disorder. It is unknown whethe...

journal_title：Schizophrenia bulletin

authors： Kim M,Hwang WJ,Park J,Kim T,Oh S,Kwon JS

更新日期：2021-01-23 00:00:00

abstract：:There is some evidence that schizotypal traits are related to a genetic or familial liability to develop schizophrenia. However, it is unclear whether the number of schizotypal traits is elevated in parents of schizophrenia patients compared with controls. This study used the Schizotypal Personality Questionnaire to i...

journal_title：Schizophrenia bulletin

authors： Appels MC,Sitskoorn MM,Vollema MG,Kahn RS

更新日期：2004-01-01 00:00:00

abstract：:Psychotic-like experiences (PLEs) increase the risk of schizophrenia and other psychotic disorders yet are common in the community. Some PLEs, such as those associated with depression, distress, and poor functioning, may confer increased risk. The aim of this study is to determine the prevalence of PLEs in a nonpsycho...

journal_title：Schizophrenia bulletin

authors： Yung AR,Buckby JA,Cotton SM,Cosgrave EM,Killackey EJ,Stanford C,Godfrey K,McGorry PD

更新日期：2006-04-01 00:00:00

abstract：:The prodrome of psychosis has become a target for early identification and for treatments that address both symptoms and risk for future psychosis. Interest and activity in this realm is now worldwide. Clinical trials with rigorous methodology have only just begun, making treatment guidelines premature. Despite the sp...

journal_title：Schizophrenia bulletin

authors： McGlashan TH,Addington J,Cannon T,Heinimaa M,McGorry P,O'Brien M,Penn D,Perkins D,Salokangas RK,Walsh B,Woods SW,Yung A

更新日期：2007-05-01 00:00:00

abstract：:Designs of clinical trials that will permit evaluation of independent, additive, and interactive effects of drugs and psychosocial treatments are described. The central feature of such designs is that they incorporate control conditions for both classes of treatment. Data from the articles in this issue are drawn upon...

journal_title：Schizophrenia bulletin

authors： Schooler NR

更新日期：1980-01-01 00:00:00

abstract：:Neurological soft signs (NSS) are well documented in individuals with schizophrenia (SZ), yet so far, the relationship between NSS and specific symptom expression is unclear. We studied 76 SZ patients using magnetic resonance imaging (MRI) to determine associations between NSS, positive symptoms, gray matter volume (G...

journal_title：Schizophrenia bulletin

authors： Wolf RC,Rashidi M,Schmitgen MM,Fritze S,Sambataro F,Kubera KM,Hirjak D

更新日期：2020-10-24 00:00:00

abstract：:Cognitive-behavioral therapy for psychosis is described. It draws on the cognitive models and therapy approach of Beck and colleagues, combined with an application of stress-vulnerability models of schizophrenia and cognitive models of psychotic symptoms. There is encouraging evidence for the efficacy of this approach...

journal_title：Schizophrenia bulletin

authors： Garety PA,Fowler D,Kuipers E

更新日期：2000-01-01 00:00:00

abstract：:Psychotic experiences may be understood as altered information processing due to aberrant neural computations. A prominent example of such neural computations is the computation of prediction errors (PEs), which signal the difference between expected and experienced events. Among other areas showing PE coding, hippoca...

journal_title：Schizophrenia bulletin

authors： Heinz A,Murray GK,Schlagenhauf F,Sterzer P,Grace AA,Waltz JA

更新日期：2019-09-11 00:00:00

abstract：:Studies indicate a high prevalence of childhood trauma in patient cohorts with established psychotic disorder and in those at risk of developing psychosis. A causal link between childhood trauma and development of psychosis has been proposed. We aimed to examine the association between experience of childhood trauma a...

journal_title：Schizophrenia bulletin

authors： Thompson AD,Nelson B,Yuen HP,Lin A,Amminger GP,McGorry PD,Wood SJ,Yung AR

更新日期：2014-05-01 00:00:00