Executive attention in schizophrenic males and the impact of COMT Val108/158Met genotype on performance on the attention network test.

abstract：:Educating the public that mental illness is a brain disease is a popular strategy for combating mental illness stigma. Evidence suggests that while such an approach reduces blame for mental illness, it may unintentionally exacerbate other components of stigma, particularly the benevolence and dangerousness stigmas. Co...

journal_title：Schizophrenia bulletin

authors： Corrigan PW,Watson AC

更新日期：2004-01-01 00:00:00

abstract：:This article focuses on the schizophrenic disorganization syndrome, which was initially described by Bleuler (who used the term "dissociation") as lying at the heart of schizophrenia. While adopting a neo-Bleulerian approach, we describe schizophrenic disorganization using a pathogenetic hypothesis and a three-part st...

journal_title：Schizophrenia bulletin

authors： Hardy-Baylé MC,Sarfati Y,Passerieux C

更新日期：2003-01-01 00:00:00

abstract：:In this issue we have tried to bring together a series of reviews describing new developments in the pharmacologic management of schizophrenia. Important progress is being made not only in medication development, but also in furthering our ability to use available treatments and treatment combinations in the most effe...

journal_title：Schizophrenia bulletin

authors： Kane JM

更新日期：1991-01-01 00:00:00

abstract：:A workshop on "Antipsychotics: Past and Future" was convened by the National Institute of Mental Health (NIMH), Division of Services and Intervention Research (DSIR), on July 14, 1998, to review the results of recent antipsychotic drug research, discuss current standards of treatment, and identify areas needing furthe...

journal_title：Schizophrenia bulletin

authors： Dawkins K,Lieberman JA,Lebowitz BD,Hsiao JK

更新日期：1999-01-01 00:00:00

abstract：:The search for a treatment of tardive dyskinesia (TD) has focused largely on cholinergic and GABAergic agents that are believed to attenuate striatal imbalances and bring about symptomatic control of dyskinetic movements. While numerous reports of the partial effectiveness of acute treatment with cholinergic or GABAer...

journal_title：Schizophrenia bulletin

authors： Kucharski LT,Unterwald EM

更新日期：1981-01-01 00:00:00

abstract：:This study quantitatively examined reasons for substance use among individuals with psychotic disorders and explored the relationship of these reasons to substance use problems and dependence. Sixty-nine people with psychotic disorders were interviewed using a battery of questionnaires called the Substance Use Scale f...

journal_title：Schizophrenia bulletin

authors： Spencer C,Castle D,Michie PT

更新日期：2002-01-01 00:00:00

abstract：:The Seventh International Congress on Schizophrenia Research was held in Santa Fe, New Mexico, in April 1999. This was the largest Congress meeting to date, with almost 1,000 presentations that covered all aspects of schizophrenia research. This article provides an account of the Congress proceedings. Several research...

journal_title：Schizophrenia bulletin

authors： Buckley PF,Buchanan RW,Tamminga CA,Schulz SC

更新日期：2000-01-01 00:00:00

abstract：:The poverty and lack of social role in the lives of many people with schizophrenia seem similar to those of people in long-term unemployment, raising the possibility that there may be some commonalities in their time use and community functioning. To test this possibility, the social anxiety, time use, and activity pa...

journal_title：Schizophrenia bulletin

authors： Hayes RL,Halford WK

更新日期：1996-01-01 00:00:00

abstract：:Recently published data from the Roscommon Family Study show that a parental diagnosis of schizotypal disorder (SPD) has a significant and specific impact on the risk for schizophrenia in siblings of index probands with schizophrenia spectrum disorders. The distribution patterns of risks for schizophrenia and SPD in p...

journal_title：Schizophrenia bulletin

authors： Battaglia M,Bellodi L

更新日期：1996-01-01 00:00:00

abstract：:Evidence suggests that dissociation is associated with psychotic experiences, particularly hallucinations, but also other symptoms. However, until now, symptom-specific relationships with dissociation have not been comprehensively synthesized. This is the first prospectively registered (CRD42017058214) meta-analysis t...

journal_title：Schizophrenia bulletin

authors： Longden E,Branitsky A,Moskowitz A,Berry K,Bucci S,Varese F

更新日期：2020-03-18 00:00:00

abstract：:People with serious mental illness (SMI) have mortality rates 2 to 3 times higher than the overall US population, largely due to cardiovascular disease. The prevalence of cardiovascular risk factors such as obesity and diabetes mellitus and other conditions, such as HIV/AIDS, is heightened in this group. Based on the ...

journal_title：Schizophrenia bulletin

authors： McGinty EE,Baller J,Azrin ST,Juliano-Bult D,Daumit GL

更新日期：2016-01-01 00:00:00

abstract：:North American outcome studies of schizophrenia conducted within the past quarter century are reviewed if their minimum average followup is 10 years and they meet at least some modern design criteria. Ten such investigations are described and summarized. Taken as a whole, they demonstrate that schizophrenia can be a c...

journal_title：Schizophrenia bulletin

authors： McGlashan TH

更新日期：1988-01-01 00:00:00

abstract：:A substantial amount of research has focused on the midbrain dopamine system and its role in emotional and motivational behaviors. In diseases in which dopamine function is compromised, patients exhibit a constellation of symptoms, suggesting that the dopamine system plays an important role in the integration of sever...

journal_title：Schizophrenia bulletin

authors： Haber SN,Fudge JL

更新日期：1997-01-01 00:00:00

abstract：:Given the variety of "organic" or "toxic" conditions that may produce, precipitate, or exacerbate psychotic disorders, it is important to attempt to clarify existing nosologies and to highlight the need for research strategies that may help to validate relevant distinctions. This review provides a brief discussion of ...

journal_title：Schizophrenia bulletin

authors： Kane JM,Selzer J

更新日期：1991-01-01 00:00:00

abstract：:The study of sexual dimorphism in brain morphology may help delineate subtypes of schizophrenia based, in part, on sex; yield insight into the relationship between brain structure and behavior; and provide a neurodevelopmental context for studying the ontogenesis of schizophrenia. Preliminary findings from an ongoing ...

journal_title：Schizophrenia bulletin

authors： Lewine RR,Gulley LR,Risch SC,Jewart R,Houpt JL

更新日期：1990-01-01 00:00:00

abstract：:Data provided by case managers in community support programs are used to analyze the problems of families providing shelter to mentally ill relatives. Factors affecting complaints in 345 family households are contrasted with factors leading to complaints in a subsample of 622 other residential alternatives. Behavioral...

journal_title：Schizophrenia bulletin

authors： Gubman GD,Tessler RC,Willis G

更新日期：1987-01-01 00:00:00

abstract：:Negative symptoms of schizophrenia remain an area of substantial unmet clinical need. By convening a consensus conference in January 2005, the NIMH has taken a leading role in stimulating a resurgence of interest in methodological considerations related to development of new medications for treating negative symptoms....

journal_title：Schizophrenia bulletin

authors： Alphs L

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear what the best method is to allow people with schizophrenia to alter their cannabis intake. OBJECTIVES:To assess the effects of specific psychological...

journal_title：Schizophrenia bulletin

authors： Pushpa-Rajah JA,McLoughlin BC,Gillies D,Rathbone J,Variend H,Kalakouti E,Kyprianou K

更新日期：2015-03-01 00:00:00

abstract：:The dopamine hypothesis of schizophrenia is usually presented in a static, rather than dynamic fashion. We propose that increased dopaminergic activity may represent a stage of a dynamic schizophrenic process rather than its cause. Dopamine, as well as other neurotransmitters, responds in an adaptive fashion to stimul...

journal_title：Schizophrenia bulletin

authors： Csernansky JG,Holman CA,Hollister LE

更新日期：1983-01-01 00:00:00

abstract：:The causal mechanism underlying the well-established relation between advancing paternal age and schizophrenia is hypothesized to involve mutational errors during spermatogenesis that occur with increasing frequency as males age. Point mutations are well known to increase with advancing paternal age while other errors...

journal_title：Schizophrenia bulletin

authors： Perrin MC,Brown AS,Malaspina D

更新日期：2007-11-01 00:00:00

abstract：:Schizophrenia (SZ) is a devastating mental disease caused by complex genetic and environmental factors. The pathological process and clinical manifestation of SZ are heterogeneous among patients, which hampers precise diagnosis and treatment of the disease. Since no objective marker for SZ has been established today, ...

journal_title：Schizophrenia bulletin

authors： Sun L,Yang X,Jiang J,Hu X,Qing Y,Wang D,Yang T,Yang C,Zhang J,Yang P,Wang P,Cai C,Wang J,He L,Wan C

更新日期：2018-06-06 00:00:00

abstract：:The variability in the response to antipsychotic medication in schizophrenia may reflect between-patient differences in neurobiology. Recent cross-sectional neuroimaging studies suggest that a poorer therapeutic response is associated with relatively normal striatal dopamine synthesis capacity but elevated anterior ci...

journal_title：Schizophrenia bulletin

authors： Egerton A,Murphy A,Donocik J,Anton A,Barker GJ,Collier T,Deakin B,Drake R,Eliasson E,Emsley R,Gregory CJ,Griffiths K,Kapur S,Kassoumeri L,Knight L,Lambe EJB,Lawrie SM,Lees J,Lewis S,Lythgoe DJ,Matthews J,McGuire

更新日期：2020-09-10 00:00:00

abstract：:Negative and positive symptoms were investigated in a sample of 72 young schizophrenic and depressed patients at followup approximately 1 1/2 years after hospital discharge. Flat affect, poverty of speech, and psychomotor retardation were included as negative symptoms, and delusions, hallucinations, and florid thought...

journal_title：Schizophrenia bulletin

authors： Pogue-Geile MF,Harrow M

更新日期：1984-01-01 00:00:00

abstract：:As part of an open clinical trial currently underway at the Max Planck Institute of Psychiatry in Munich, the feasibility of behavioral family management (Falloon et al. 1984) for schizophrenia in combination with two different neuroleptic medication strategies was investigated. The treatment approaches were psychoedu...

journal_title：Schizophrenia bulletin

authors： Wiedemann G,Hahlweg K,Hank G,Feinstein E,Müller U,Dose M

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To investigate patterns of mental health service and antipsychotic use following a first-episode schizophrenia (FES) and to examine the role of the treatment setting in which individuals are first diagnosed. METHOD:Analysis of de-identified administrative claims data from the OptumLabs Data Warehouse was use...

journal_title：Schizophrenia bulletin

authors： Gilmer TP,van der Ven E,Susser E,Dixon LB,Olfson M

更新日期：2020-01-04 00:00:00

abstract：:Persistent negative symptoms represent an alternative approach for assessing negative symptoms in the context of clinical trials. Persistent negative symptoms are designed to capture those symptoms that lead to functional impairment but are currently understudied and for which there are no currently available effectiv...

journal_title：Schizophrenia bulletin

authors： Buchanan RW

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Cannabis use has been identified as a potent predictor of the earlier onset of psychosis, but meta-analysis has not indicated that it has a clear effect in established psychosis. AIM:To assess the association between cannabis and outcomes, including whether change in cannabis use affects symptoms and functi...

journal_title：Schizophrenia bulletin

authors： Barrowclough C,Emsley R,Eisner E,Beardmore R,Wykes T

更新日期：2013-03-01 00:00:00

abstract：:Child maltreatment is a widespread public health problem associated with a range of mental health disorders later in life. In order to effectively address these disorders, there is a need to understand more about the mental health consequences of different types of child maltreatment. This study examines the associati...

journal_title：Schizophrenia bulletin

authors： Abajobir AA,Kisely S,Scott JG,Williams G,Clavarino A,Strathearn L,Najman JM

更新日期：2017-09-01 00:00:00

abstract：:A selective review of the negative symptoms of schizophrenia is an appropriate article to result from the festschrift honoring William T. Carpenter Jr, as he has made substantial contributions in this area. This review assesses progress in 3 areas in which he has been an important investigator: the distinction between...

journal_title：Schizophrenia bulletin

authors： Kirkpatrick B

更新日期：2014-03-01 00:00:00

abstract：:The article that follows is part of the Schizophrenia Bulletin's ongoing First Person Account series. We hope that mental health professionals--the Bulletin's primary audience--will take this opportunity to learn about the issues and difficulties confronted by consumers of mental health care. In addition, we hope that...

journal_title：Schizophrenia bulletin

authors： Ribar AV

更新日期：2004-01-01 00:00:00