Variability and the dopamine hypothesis of schizophrenia.

Abstract:

:The dopamine hypothesis of schizophrenia is usually presented in a static, rather than dynamic fashion. We propose that increased dopaminergic activity may represent a stage of a dynamic schizophrenic process rather than its cause. Dopamine, as well as other neurotransmitters, responds in an adaptive fashion to stimuli that perturb the homeostasis of the brain. One such stimulus could be an epileptic focus in the temporal lobe. Other such stimuli undoubtedly also exist.

journal_name

Schizophr Bull

journal_title

Schizophrenia bulletin

authors

Csernansky JG,Holman CA,Hollister LE

doi

10.1093/schbul/9.3.325

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

325-8

issue

3

eissn

0586-7614

issn

1745-1701

journal_volume

9

pub_type

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