Symptomatic treatment of tardive dyskinesia: a word of caution.

abstract：:Cognitive remediation is a behavioral intervention designed to improve cognition in people who have suffered a decline in neuropsychological functioning. The application of cognitive remediation for people with schizophrenia has become increasingly popular. In this article we attempt to determine what factors moderate...

journal_title：Schizophrenia bulletin

authors： Medalia A,Richardson R

更新日期：2005-10-01 00:00:00

abstract：:Studies indicate a high prevalence of childhood trauma in patient cohorts with established psychotic disorder and in those at risk of developing psychosis. A causal link between childhood trauma and development of psychosis has been proposed. We aimed to examine the association between experience of childhood trauma a...

journal_title：Schizophrenia bulletin

authors： Thompson AD,Nelson B,Yuen HP,Lin A,Amminger GP,McGorry PD,Wood SJ,Yung AR

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Previous studies of nonclinical samples exhibiting schizotypal traits have provided support for the existence of a continuous distribution of psychotic symptoms in the general population. Few studies, however, have examined the neural correlates of psychometric schizotypy using structural and diffusion tenso...

journal_title：Schizophrenia bulletin

authors： DeRosse P,Nitzburg GC,Ikuta T,Peters BD,Malhotra AK,Szeszko PR

更新日期：2015-01-01 00:00:00

abstract：:This study examined the course of illness and factors affecting it in schizophrenias with onset between the ages of 14 and 18. Noteworthy in comparison to findings from other followup studies is the higher proportion of chronic courses of illness, about 50 percent. In addition, the type of course of illness correspond...

journal_title：Schizophrenia bulletin

authors： Krausz M,Müller-Thomsen T

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Genome-wide association studies (GWAS) implicate single nucleotide polymorphisms (SNPs) on chromosome 6p21.3-22.1, the human leukocyte antigen (HLA) region, as common risk factors for schizophrenia (SZ). Other studies implicate viral and protozoan exposure. Our study tests chromosome 6p SNPs for effects on S...

journal_title：Schizophrenia bulletin

authors： Bamne M,Wood J,Chowdari K,Watson AM,Celik C,Mansour H,Klei L,Gur RC,Bradford LD,Calkins ME,Santos AB,Edwards N,Kwentus J,McEvoy JP,Allen TB,Savage RM,Nasrallah HA,Gur RE,Perry RT,Go RC,Devlin B,Yolken R,Nimgao

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Stressful life events have been implicated in the onset of psychotic disorders, but there are few robust studies. We sought to examine the nature and magnitude of associations between adult life events and difficulties and first-episode psychoses, particularly focusing on contextual characteristics, including...

journal_title：Schizophrenia bulletin

authors： Beards S,Fisher HL,Gayer-Anderson C,Hubbard K,Reininghaus U,Craig TJ,Di Forti M,Mondelli V,Pariante C,Dazzan P,Murray R,Morgan C

更新日期：2020-07-08 00:00:00

abstract：:There is some support for the hypothesis that the factor structure of schizophrenia symptoms is similar to the factor structure of schizotypal symptoms in nonschizophrenia populations. However, no studies to date have examined schizotypal symptoms in patients with personality disorders. In this study, confirmatory fac...

journal_title：Schizophrenia bulletin

authors： Bergman AJ,Harvey PD,Mitropoulou V,Aronson A,Marder D,Silverman J,Trestman R,Siever LJ

更新日期：1996-01-01 00:00:00

abstract：:The validity of a Hindi version of the Diagnostic Interview for Genetic Studies (DIGS) was investigated. The original English version was initially translated into Hindi. The Hindi version was then back-translated and compared with the original. Next, a group of psychiatric inpatients and outpatients were interviewed ...

journal_title：Schizophrenia bulletin

authors： Deshpande SN,Mathur MN,Das SK,Bhatia T,Sharma S,Nimgaonkar VL

更新日期：1998-01-01 00:00:00

abstract：:Evidence for the existence of a genetic factor in the etiology of a significant proportion of the people diagnosed as having a schizophrenic disorder is reviewed. It is suggested that whatever is transmitted genetically need not be inherently pathologic and/or pathogenic. It is argued that only people who have certain...

journal_title：Schizophrenia bulletin

authors： Cancro R

更新日期：1979-01-01 00:00:00

abstract：:Gender effects have been reported quite consistently in schizophrenia, with male patients having an earlier age of onset, poorer functional outcome, greater negative symptoms and cognitive impairment, and less severe positive symptoms. Because age of onset, cognitive impairments, and negative symptoms are all correlat...

journal_title：Schizophrenia bulletin

authors： Moriarty PJ,Lieber D,Bennett A,White L,Parrella M,Harvey PD,Davis KL

更新日期：2001-01-01 00:00:00

abstract：:Kraepelin said severe mental illness was due to 2 diseases subsequently characterized as disorders of thought vs disorders of mood, ie, the Kraepelinian dichotomy. Schizophrenia, traditionally considered the disorder of thought, has been defined by the presence of hallucinations, delusions, catatonia, and disorganizat...

journal_title：Schizophrenia bulletin

authors： Raymond Lake C

更新日期：2008-01-01 00:00:00

abstract：:While previous studies have found an increased incidence of schizophrenia in some immigrant groups, differences in age of onset in these groups has not been examined. The purpose of this study was to compare age of first hospitalization of (1) native-born people versus immigrants, (2) immigrants from different countri...

journal_title：Schizophrenia bulletin

authors： Rabinowitz J,Fennig S

更新日期：2002-01-01 00:00:00

abstract：:The role of gender in schizophrenia is explored, and literature on gender and schizophrenia is critically reviewed. The importance of investigating gender differences in schizophrenia is underscored by the lack of sufficient research in this area to date and the comparative neglect of sociocultural issues during the "...

journal_title：Schizophrenia bulletin

authors： Nasser EH,Walders N,Jenkins JH

更新日期：2002-01-01 00:00:00

abstract：:Schizophrenia (SZ) is a devastating mental disease caused by complex genetic and environmental factors. The pathological process and clinical manifestation of SZ are heterogeneous among patients, which hampers precise diagnosis and treatment of the disease. Since no objective marker for SZ has been established today, ...

journal_title：Schizophrenia bulletin

authors： Sun L,Yang X,Jiang J,Hu X,Qing Y,Wang D,Yang T,Yang C,Zhang J,Yang P,Wang P,Cai C,Wang J,He L,Wan C

更新日期：2018-06-06 00:00:00

abstract：:The dopamine hypothesis of schizophrenia implies that alterations in the dopamine system cause functional abnormalities in the brain that may converge to aberrant salience attribution and eventually lead to psychosis. Indeed, widespread brain disconnectivity across the psychotic spectrum has been revealed by resting-s...

journal_title：Schizophrenia bulletin

authors： Rössler J,Unterassner L,Wyss T,Haker H,Brugger P,Rössler W,Wotruba D

更新日期：2019-04-25 00:00:00

abstract：:This study examined the relation between maternal prepregnant body mass index (BMI) and development of schizophrenia and schizophrenia spectrum disorders in adult offspring from the Prenatal Determinants of Schizophrenia Study. The study drew on a previously studied cohort of births occurring between 1959 and 1967 to ...

journal_title：Schizophrenia bulletin

authors： Schaefer CA,Brown AS,Wyatt RJ,Kline J,Begg MD,Bresnahan MA,Susser ES

更新日期：2000-01-01 00:00:00

abstract：:There is an increasing emphasis on identifying individuals with schizophrenia earlier and earlier in their disease process, with the assumption that earlier identification translates into earlier treatment, which translates into improved outcome. Unfortunately, one age cohort, children under 13 years of age, have been...

journal_title：Schizophrenia bulletin

authors： Ross RG,Schaeffer J,Compagnon N,Heinlein S,Beresford C,Farley G

更新日期：2003-01-01 00:00:00

abstract：:The normal developmental series of brains in the Yakovlev Collection has been examined to explore the possibility that various brain regions implicated in schizophrenia may show changes in myelination during late adolescence, a period coinciding with the appearance of early symptoms of this disorder. The prefrontal, c...

journal_title：Schizophrenia bulletin

authors： Benes FM

更新日期：1989-01-01 00:00:00

abstract：:Social cognitive deficits are associated with psychotic symptoms, but the nature of this association remains unknown. This study uses a genetically sensitive cross-trait cross-sibling design to investigate the nature of the overlap between both phenotypes. A sample of 1032 patients, 1017 of their healthy siblings, and...

journal_title：Schizophrenia bulletin

authors： Fett AK,Maat A,GROUP Investigators.

更新日期：2013-01-01 00:00:00

abstract：:The sex chromosomes are strong candidates for a genetic locus for schizophrenia and the affective psychoses. Gender differences in the clinical expression of illness and familial risks, concordance for gender and illness in relatives, and an association of X chromosome anomalies with psychosis suggest an X chromosome ...

journal_title：Schizophrenia bulletin

authors： DeLisi LE,Crow TJ

更新日期：1989-01-01 00:00:00

abstract：:In addition to introducing the six articles joined by our thematic outlook, this article addresses the importance of subcortical structures as they may be related to information processing and the life experience of schizophrenic patients. This is a heuristic exercise aimed at bridging the conceptual gaps between clin...

journal_title：Schizophrenia bulletin

authors： Patterson T

更新日期：1987-01-01 00:00:00

abstract：:Methodological issues involved in assessing the prevalence of substance abuse in schizophrenia are discussed, and previous research in this area is comprehensively reviewed. Many studies suffer from methodological shortcomings, including the lack of diagnostic rigor, adequate sample sizes, and simultaneous assessment ...

journal_title：Schizophrenia bulletin

authors： Mueser KT,Yarnold PR,Levinson DF,Singh H,Bellack AS,Kee K,Morrison RL,Yadalam KG

更新日期：1990-01-01 00:00:00

abstract：:The purpose of this study was to investigate the construct validity and the test-retest reliability of the willingness to pay (WTP) method for estimating health state preferences associated with side effects of antipsychotic medication. Ninety-six schizophrenia patients on antipsychotics were asked (1) how much they w...

journal_title：Schizophrenia bulletin

authors： Sevy S,Nathanson K,Schechter C,Fulop G

更新日期：2001-01-01 00:00:00

abstract：INTRODUCTION:ABT-288 is a highly potent histamine-3 receptor antagonist that has demonstrated pro-cognitive effects in preclinical models relevant to schizophrenia. This study evaluated the efficacy and safety of two doses of ABT-288 in the treatment of cognitive impairment associated with schizophrenia. METHODS:A ran...

journal_title：Schizophrenia bulletin

authors： Haig GM,Bain E,Robieson W,Othman AA,Baker J,Lenz RA

更新日期：2014-11-01 00:00:00

abstract：:Schizophrenia affects people of all age groups. Treatment plans for older adults with schizophrenia must consider the effects of age on the course of the illness as well as on the response to antipsychotics and to psychosocial interventions. Positive symptoms of schizophrenia tend to become less severe, substance abus...

journal_title：Schizophrenia bulletin

authors： Jeste DV,Maglione JE

更新日期：2013-09-01 00:00:00

abstract：:Self-experience anomalies are elementary features of schizophrenic pathology. Such deficits can have a profound impact on self-other relationship, but how they are related through aberrant brain function remains poorly understood. In this functional magnetic resonance imaging (fMRI) study, we provide new evidence for ...

journal_title：Schizophrenia bulletin

authors： Ebisch SJ,Mantini D,Northoff G,Salone A,De Berardis D,Ferri F,Ferro FM,Di Giannantonio M,Romani GL,Gallese V

更新日期：2014-09-01 00:00:00

abstract：:Individuals with psychoses have brain alterations, particularly in frontal and temporal cortices, that may be particularly prominent, already at illness onset, in those more likely to have poorer symptom remission following treatment with the first antipsychotic. The identification of strong neuroanatomical markers of...

journal_title：Schizophrenia bulletin

authors： Dazzan P,Lawrence AJ,Reinders AATS,Egerton A,van Haren NEM,Merritt K,Barker GJ,Perez-Iglesias R,Sendt KV,Demjaha A,Nam KW,Sommer IE,Pantelis C,Wolfgang Fleischhacker W,van Rossum IW,Galderisi S,Mucci A,Drake R,Lewis S

更新日期：2020-10-15 00:00:00

abstract：:The diagnosis of schizophrenia is thought to embrace several distinct subgroups. The manifold entities in a single clinical patient group increase the variance of biological measures, deflate the group-level estimates of causal factors, and mask the presence of treatment effects. However, reliable neurobiological boun...

journal_title：Schizophrenia bulletin

authors： Pan Y,Pu W,Chen X,Huang X,Cai Y,Tao H,Xue Z,Mackinley M,Limongi R,Liu Z,Palaniyappan L

更新日期：2020-04-10 00:00:00

abstract：:Advances in treatment technologies and development of evidence-based standards of care demand better methods for routine assessment of outcomes for schizophrenia in systems of care. This article describes the development and psychometrics of a new instrument to assess outcomes of routine care for persons with schizoph...

journal_title：Schizophrenia bulletin

authors： Lehman AF,Fischer EP,Postrado L,Delahanty J,Johnstone BM,Russo PA,Crown WH

更新日期：2003-01-01 00:00:00

abstract：:At the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) New Approaches Conference, a discussion group focused on directions for future research that are critical to enhancing our understanding of the distinctions among key cognitive domains that have relevance for the development of c...

journal_title：Schizophrenia bulletin

authors： Nuechterlein KH,Robbins TW,Einat H

更新日期：2005-10-01 00:00:00