Differentiating patterns of amygdala-frontal functional connectivity in schizophrenia and bipolar disorder.

abstract：:This study examined the content of subscales within a multidimensional scale of self-reported schizotypy and their subsequent interrelationship by means of confirmatory factor analysis (CFA). Neither single-factor nor four-factor models provided good fits to the data; two-factor and three-factor models showed very goo...

journal_title：Schizophrenia bulletin

authors： Venables PH,Rector NA

更新日期：2000-01-01 00:00:00

abstract：:Schizophrenia is a disabling clinical syndrome found across the world. While the incidence and clinical expression of this illness are strongly influenced by ethnic factors, it is unclear whether patients from different ethnicities show distinct brain deficits. In this multicentre study, we used structural Magnetic Re...

journal_title：Schizophrenia bulletin

authors： Gong Q,Dazzan P,Scarpazza C,Kasai K,Hu X,Marques TR,Iwashiro N,Huang X,Murray RM,Koike S,David AS,Yamasue H,Lui S,Mechelli A

更新日期：2015-11-01 00:00:00

abstract：:The early detection and intervention in psychoses prior to their first episode are presently based on the symptomatic ultra-high-risk and the basic symptom criteria. Current models of symptom development assume that basic symptoms develop first, followed by attenuated and, finally, frank psychotic symptoms, though int...

journal_title：Schizophrenia bulletin

authors： Jimeno N,Gomez-Pilar J,Poza J,Hornero R,Vogeley K,Meisenzahl E,Haidl T,Rosen M,Klosterkötter J,Schultze-Lutter F

更新日期：2020-07-08 00:00:00

abstract：:Patients with schizophrenia display an impaired sense of temporal continuity, and we showed that they judge events as being simultaneous even in case of large onset asynchronies. We check here whether this means a fusion of events in time, or on the contrary, a segregation of events and a deficit in coding time-event ...

journal_title：Schizophrenia bulletin

authors： Lalanne L,van Assche M,Giersch A

更新日期：2012-05-01 00:00:00

abstract：:Disruption of sleep/wake cycles is common in patients with schizophrenia and correlates with cognitive and affective abnormalities. Mice deficient in stable tubule only polypeptide (STOP) show cognitive, behavioral, and neurobiological deficits that resemble those seen in patients with schizophrenia, but little is kno...

journal_title：Schizophrenia bulletin

authors： Profitt MF,Deurveilher S,Robertson GS,Rusak B,Semba K

更新日期：2016-09-01 00:00:00

abstract：:Distinguishing between brain-damaged and schizophrenic patients remains a significant clinical problem. However, substantive and methodological difficulties have led to discouragement and consequent loss of interest in this area of differential diagnosis. Several models for making this distinction were proposed: cogni...

journal_title：Schizophrenia bulletin

authors： Goldstein G

更新日期：1978-01-01 00:00:00

abstract：:Although there is recent evidence that cells from the peripheral immune system can gain access to the central nervous system in certain conditions such as multiple sclerosis, their role has not been assessed in psychosis. Here, we aimed to explore whether blood cell count was associated with brain volume and/or clinic...

journal_title：Schizophrenia bulletin

authors： Núñez C,Stephan-Otto C,Usall J,Bioque M,Lobo A,González-Pinto A,Pina-Camacho L,Vieta E,Castro-Fornieles J,Rodriguez-Jimenez R,Butjosa A,Janssen J,Cabrera B,Parellada M,Bernardo M,PEPs group.

更新日期：2019-06-18 00:00:00

abstract：OBJECTIVE:Both neurocognitive impairments and a history of childhood abuse are highly prevalent in patients with schizophrenia. Childhood trauma has been associated with memory impairment as well as hippocampal volume reduction in adult survivors. The aim of the following study was to examine the contribution of childh...

journal_title：Schizophrenia bulletin

authors： Shannon C,Douse K,McCusker C,Feeney L,Barrett S,Mulholland C

更新日期：2011-05-01 00:00:00

abstract：:The aim of the study was to evaluate the latent structure of DSM-IV schizotypal personality disorder (SPD) diagnostic criteria. The sample consisted of 564 consecutively admitted inpatients and outpatients. Exploratory latent class analysis identified a four-class model as the best fitting model for DSM-IV SPD criteri...

journal_title：Schizophrenia bulletin

authors： Fossati A,Maffei C,Battaglia M,Bagnato M,Donati D,Donini M,Fiorilli M,Novella L

更新日期：2001-01-01 00:00:00

abstract：:The electroencephalogram (EEG) recorded from the human scalp is widely used to study cognitive and brain functions in schizophrenia. Current research efforts are primarily devoted to the assessment of event-related potentials (ERPs) and event-related oscillations (EROs), extracted from the ongoing EEG, in patients wit...

journal_title：Schizophrenia bulletin

authors： van der Stelt O,Belger A

更新日期：2007-07-01 00:00:00

abstract：:Abnormalities in both time processing and dopamine (DA) neurotransmission have been observed in schizophrenia. Time processing seems to be linked to DA neurotransmission. The cognitive dysmetria hypothesis postulates that psychosis might be a manifestation of the loss of coordination of mental processes due to impaire...

journal_title：Schizophrenia bulletin

authors： Lošák J,Hüttlová J,Lipová P,Marecek R,Bareš M,Filip P,Žubor J,Ustohal L,Vanícek J,Kašpárek T

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Stressful life events have been implicated in the onset of psychotic disorders, but there are few robust studies. We sought to examine the nature and magnitude of associations between adult life events and difficulties and first-episode psychoses, particularly focusing on contextual characteristics, including...

journal_title：Schizophrenia bulletin

authors： Beards S,Fisher HL,Gayer-Anderson C,Hubbard K,Reininghaus U,Craig TJ,Di Forti M,Mondelli V,Pariante C,Dazzan P,Murray R,Morgan C

更新日期：2020-07-08 00:00:00

abstract：:Phenomenological research suggests that pure manic and depressive states are less common than mixtures of the two and that the two poles of mood are characterized by opposite ways of experiencing time. In mania, the subjective experience of time is sped up and in depression it is slowed down, perhaps reflecting differ...

journal_title：Schizophrenia bulletin

authors： Ghaemi SN

更新日期：2007-01-01 00:00:00

abstract：:Clinical descriptions of perceptual and attentional anomalies in schizophrenia emphasize phenomena such as flooding, or inundation, by sensory stimuli. A failure of sensory "gating" mechanisms in the brain is hypothesized to account for these symptoms, and this hypothesis has led to a marked interest in their putative...

journal_title：Schizophrenia bulletin

authors： Bunney WE Jr,Hetrick WP,Bunney BG,Patterson JV,Jin Y,Potkin SG,Sandman CA

更新日期：1999-01-01 00:00:00

abstract：INTRODUCTION:ABT-288 is a highly potent histamine-3 receptor antagonist that has demonstrated pro-cognitive effects in preclinical models relevant to schizophrenia. This study evaluated the efficacy and safety of two doses of ABT-288 in the treatment of cognitive impairment associated with schizophrenia. METHODS:A ran...

journal_title：Schizophrenia bulletin

authors： Haig GM,Bain E,Robieson W,Othman AA,Baker J,Lenz RA

更新日期：2014-11-01 00:00:00

abstract：:Every year numerous reports on antipsychotic drug trials are being published in neuropsychiatric journals, adding new information to our knowledge in the field. The information however is often hard for the reader to interpret, sometimes contradictory to comparable available studies and leaves more questions open than...

journal_title：Schizophrenia bulletin

authors： Leucht S,Heres S,Hamann J,Kane JM

更新日期：2008-03-01 00:00:00

abstract：:Secondary prevention in schizophrenia is still not good enough, and the authors of the articles in this issue of Schizophrenia Bulletin present important new knowledge that may increase earlier detection and treatment. This final article discusses some of their main findings in relation to clinical consequences and ne...

journal_title：Schizophrenia bulletin

authors： Vaglum P

更新日期：1996-01-01 00:00:00

abstract：:The dopamine hypothesis of schizophrenia implies that alterations in the dopamine system cause functional abnormalities in the brain that may converge to aberrant salience attribution and eventually lead to psychosis. Indeed, widespread brain disconnectivity across the psychotic spectrum has been revealed by resting-s...

journal_title：Schizophrenia bulletin

authors： Rössler J,Unterassner L,Wyss T,Haker H,Brugger P,Rössler W,Wotruba D

更新日期：2019-04-25 00:00:00

abstract：:Schizophrenia elevates the risk for aggressive behavior and violent crime, and different approaches have been used to manage this problem. The results of such treatments vary. One reason for this variation is that aggressive behavior in schizophrenia is heterogeneous in origin. This heterogeneity has usually not been ...

journal_title：Schizophrenia bulletin

authors： Volavka J,Citrome L

更新日期：2011-09-01 00:00:00

abstract：:A critique is offered of Samuels' article suggesting that reported sex differences in concordance rates for schizophrenia are either methodological artifacts or a function of sociological processes. Evidence of sex differences in age of onset, clinical expression, concordance rates among primary relatives, and premorb...

journal_title：Schizophrenia bulletin

authors： Lewine RR

更新日期：1979-01-01 00:00:00

abstract：:In this issue we have tried to bring together a series of reviews describing new developments in the pharmacologic management of schizophrenia. Important progress is being made not only in medication development, but also in furthering our ability to use available treatments and treatment combinations in the most effe...

journal_title：Schizophrenia bulletin

authors： Kane JM

更新日期：1991-01-01 00:00:00

abstract：:In subjects at risk for psychosis, the studies on gray matter volume (GMV) predominantly reported volume loss compared with healthy controls (CON). However, other important morphological measurements such as cortical surface area (CSA) and cortical thickness (CT) were not systematically compared. So far, samples mostl...

journal_title：Schizophrenia bulletin

authors： Buechler R,Wotruba D,Michels L,Theodoridou A,Metzler S,Walitza S,Hänggi J,Kollias S,Rössler W,Heekeren K

更新日期：2020-12-01 00:00:00

abstract：:Persons with schizophrenia have a reduced life expectancy largely due to death from natural causes. Factors that have been previously associated with excess mortality include cigarette smoking and antipsychotic medication. The role of other environmental factors such as exposure to infectious agents has been the subje...

journal_title：Schizophrenia bulletin

authors： Dickerson F,Stallings C,Origoni A,Schroeder J,Khushalani S,Yolken R

更新日期：2014-07-01 00:00:00

abstract：:The present article reports findings on intelligence and personality functioning during the school period and at adolescence in a sample of kibbutz and urban Israeli children at risk for schizophrenia, as measured by a standard psychological test battery. On the first round of testing it was found that the index subje...

journal_title：Schizophrenia bulletin

authors： Sohlberg SC

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:Early nonresponse to antipsychotics appears to predict subsequent nonresponse to treatment when assessed in randomized controlled trials of predominately acute inpatients treated for schizophrenia. This study assessed the predictive accuracy of early nonresponse to treatment and its clinical, functional, and ...

journal_title：Schizophrenia bulletin

authors： Ascher-Svanum H,Nyhuis AW,Faries DE,Kinon BJ,Baker RW,Shekhar A

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Abnormalities in the neurophysiological measures P300 amplitude and latency constitute endophenotypes for psychosis. Disrupted-in-Schizophrenia-1 (DISC1) has been proposed as a promising susceptibility gene for schizophrenia, and a previous study has suggested that it is associated with P300 deficits in sc...

journal_title：Schizophrenia bulletin

authors： Shaikh M,Hall MH,Schulze K,Dutt A,Li K,Williams I,Walshe M,Constante M,Broome M,Picchioni M,Toulopoulou T,Collier D,Stahl D,Rijsdijk F,Powell J,Murray RM,Arranz M,Bramon E

更新日期：2013-01-01 00:00:00

abstract：:Pharmacologic agents currently used or being studied for the treatment of schizophrenia are reviewed. Neuroleptic medications are still the mainstay of treatment, but recent studies suggest new approaches to dosage and to the treatment of acute psychosis. Lithium is beneficial in psychotic illnesses with acute onset a...

journal_title：Schizophrenia bulletin

authors： Donaldson SR,Gelenberg AJ,Baldessarini RJ

更新日期：1983-01-01 00:00:00

abstract：:Cognitive disruption in schizophrenia is associated with altered patterns of spatiotemporal interaction associated with multiple electroencephalogram (EEG) frequency bands in cortex. In particular, changes in the generation of gamma (30-80 Hz) and beta2 (20-29 Hz) rhythms correlate with observed deficits in communicat...

journal_title：Schizophrenia bulletin

authors： Roopun AK,Cunningham MO,Racca C,Alter K,Traub RD,Whittington MA

更新日期：2008-09-01 00:00:00

abstract：:Many brain regions and circuits have been implicated in the neuropathology of schizophrenia. Drs. Bogerts and Jones have reviewed the evidence that links the disorder to temporal limbic structures and to frontal-thalamic circuits, respectively. Each article is an important update on what we know about the relevance of...

journal_title：Schizophrenia bulletin

authors： Weinberger DR

更新日期：1997-01-01 00:00:00

abstract：:We found diurnal weight gain to be abnormal among 93 chronically psychotic patients, most of whom had schizophrenia. They were weighed at 7 a.m. and 4 p.m. weekly for 3 weeks. We normalized the diurnal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the differenc...

journal_title：Schizophrenia bulletin

authors： Vieweg WV,Godleski LS,Graham P,Kellogg EJ,Goldman F,Barber J,Bayliss EV,Glick JL,Hundley PL,Yank GR

更新日期：1989-01-01 00:00:00