A Neuroanatomical Signature for Schizophrenia Across Different Ethnic Groups.

abstract：:Similarities in clinical course, age of onset, geographical distribution, and immunological responses of patients with schizophrenia and multiple sclerosis (MS) suggest that these two common illnesses of young adults may belong to a similar class of disorders. This review examines some of the similarities and differen...

journal_title：Schizophrenia bulletin

authors： Stevens JR

更新日期：1988-01-01 00:00:00

abstract：:Lifetime prevalence of psychotic disorders varies widely across studies. Epidemiological surveys have rarely examined prevalences of specific psychotic disorders other than schizophrenia, and the majority used a single-phase design without employing clinical reappraisal interview for diagnostic verification. The curre...

journal_title：Schizophrenia bulletin

authors： Chang WC,Wong CSM,Chen EYH,Lam LCW,Chan WC,Ng RMK,Hung SF,Cheung EFC,Sham PC,Chiu HFK,Lam M,Lee EHM,Chiang TP,Chan LK,Lau GKW,Lee ATC,Leung GTY,Leung JSY,Lau JTF,van Os J,Lewis G,Bebbington P

更新日期：2017-10-21 00:00:00

abstract：:Although weight gain is a serious but variable adverse effect of antipsychotics that has genetic underpinnings, a comprehensive meta-analysis of pharmacogenetics of antipsychotic-related weight gain is missing. In this review, random effects meta-analyses were conducted for dominant and recessive models on association...

journal_title：Schizophrenia bulletin

authors： Zhang JP,Lencz T,Zhang RX,Nitta M,Maayan L,John M,Robinson DG,Fleischhacker WW,Kahn RS,Ophoff RA,Kane JM,Malhotra AK,Correll CU

更新日期：2016-11-01 00:00:00

abstract：:The study of sexual dimorphism in brain morphology may help delineate subtypes of schizophrenia based, in part, on sex; yield insight into the relationship between brain structure and behavior; and provide a neurodevelopmental context for studying the ontogenesis of schizophrenia. Preliminary findings from an ongoing ...

journal_title：Schizophrenia bulletin

authors： Lewine RR,Gulley LR,Risch SC,Jewart R,Houpt JL

更新日期：1990-01-01 00:00:00

abstract：:We have previously reported on typically paranoid schizophrenic patients who attempted to see the President or other prominent American political figures based on hallucinations or delusional beliefs. By obtaining arrest records on these White House Cases (WHCs), we were able to determine which individuals had murder ...

journal_title：Schizophrenia bulletin

authors： Shore D,Filson CR,Johnson WE

更新日期：1988-01-01 00:00:00

abstract：:Schizophrenia patients have higher scores on neurological soft-signs (NSS) and show greater deficits on a variety of neuropsychological tests than normal control subjects and mixed groups of psychiatric patients. Among chronic schizophrenia patients it is unclear which of these types of deficits most strongly differen...

journal_title：Schizophrenia bulletin

authors： Smith RC,Kadewari RP,Rosenberger JR,Bhattacharyya A

更新日期：1999-01-01 00:00:00

abstract：:A workshop on "Antipsychotics: Past and Future" was convened by the National Institute of Mental Health (NIMH), Division of Services and Intervention Research (DSIR), on July 14, 1998, to review the results of recent antipsychotic drug research, discuss current standards of treatment, and identify areas needing furthe...

journal_title：Schizophrenia bulletin

authors： Dawkins K,Lieberman JA,Lebowitz BD,Hsiao JK

更新日期：1999-01-01 00:00:00

abstract：:There is an increasing emphasis on identifying individuals with schizophrenia earlier and earlier in their disease process, with the assumption that earlier identification translates into earlier treatment, which translates into improved outcome. Unfortunately, one age cohort, children under 13 years of age, have been...

journal_title：Schizophrenia bulletin

authors： Ross RG,Schaeffer J,Compagnon N,Heinlein S,Beresford C,Farley G

更新日期：2003-01-01 00:00:00

abstract：:A frontostriatal hypothesis of schizophrenia is advanced which takes into account evidence from studies of neurochemical pathology, functional imaging, cognitive neuropsychology, and experimental and clinical psychopharmacology, in addition to factor analyses of the symptomatic heterogeneity of this disorder. This evi...

journal_title：Schizophrenia bulletin

authors： Robbins TW

更新日期：1990-01-01 00:00:00

abstract：:Numerous studies have differentiated schizophrenic patients and normal controls in electroencephalography (EEG) spectral patterns recorded at rest. We replicated the resting EEG spectral differences between these groups and observed significant differences in periodic photic stimuli on the EEG spectra. Drug-free schiz...

journal_title：Schizophrenia bulletin

authors： Jin Y,Potkin SG,Rice D,Sramek J,Costa J,Isenhart R,Heh C,Sandman CA

更新日期：1990-01-01 00:00:00

abstract：:As part of a long-term study in schizophrenia, a model of family intervention has been developed which attempts to diminish relapse rates of schizophrenic patients. This model reflects theoretical and research findings which suggest that certain patients have a "core psychological deficit" that might increase vulnerab...

journal_title：Schizophrenia bulletin

authors： Anderson CM,Hogarty GE,Reiss DJ

更新日期：1980-01-01 00:00:00

abstract：:Evidence for the existence of a genetic factor in the etiology of a significant proportion of the people diagnosed as having a schizophrenic disorder is reviewed. It is suggested that whatever is transmitted genetically need not be inherently pathologic and/or pathogenic. It is argued that only people who have certain...

journal_title：Schizophrenia bulletin

authors： Cancro R

更新日期：1979-01-01 00:00:00

abstract：:Identifying predictors and elucidating the fundamental mechanisms underlying onset of psychosis are critical for the development of targeted preemptive interventions. This article presents a selective review of findings on risk prediction algorithms and potential mechanisms of onset in youth at clinical high-risk for ...

journal_title：Schizophrenia bulletin

authors： Cannon TD

更新日期：2016-07-01 00:00:00

abstract：:The multilevel control of eye movements for the researcher in the schizophrenic disease process includes the saccadic trajectory, the dual mode tracking system, and schematically directed eye movements in fixation, in scanpaths, and other looking strategies, and in reading. Coordination of eye movements with head move...

journal_title：Schizophrenia bulletin

authors： Stark L

更新日期：1983-01-01 00:00:00

abstract：:A series of human and animal investigations has suggested that altered expression and function of the alpha7-nicotinic cholinergic receptor may be responsible for the auditory sensory gating deficit characterized in schizophrenia patients and their relatives as diminished suppression of an auditory-evoked response (P5...

journal_title：Schizophrenia bulletin

authors： Adler LE,Olincy A,Waldo M,Harris JG,Griffith J,Stevens K,Flach K,Nagamoto H,Bickford P,Leonard S,Freedman R

更新日期：1998-01-01 00:00:00

abstract：:Thalamus abnormalities are common in neurological and psychiatric illnesses. Therefore, it is essential to understand the properties of the thalamus-related networks. The thalamic reticular nucleus (TRN) is a thin GABAergic layer interface strategically located between the thalamus and the neocortex. It is, at the ver...

journal_title：Schizophrenia bulletin

authors： Pinault D

更新日期：2011-03-01 00:00:00

abstract：:Studies on the long-term development and early predictors of treatment-resistant schizophrenia (TRS) and clozapine-resistant TRS (CR-TRS) in patients with first-episode schizophrenia-spectrum disorders (FES) are limited and have not considered the impact of early intervention services (EIS). This study aimed to explor...

journal_title：Schizophrenia bulletin

authors： Chan SKW,Chan HYV,Honer WG,Bastiampillai T,Suen YN,Yeung WS,Lam M,Lee WK,Ng RMK,Hui CLM,Chang WC,Lee EHM,Chen EYH

更新日期：2020-10-12 00:00:00

abstract：:Genetic factors are known to influence both risk for schizophrenia (SZ) and variation in brain structure. A pressing question is whether the genetic underpinnings of brain phenotype and the disorder overlap. Using multivariate analytic methods and focusing on 1,402 common single-nucleotide polymorphisms (SNPs) mapped ...

journal_title：Schizophrenia bulletin

authors： Chen J,Calhoun VD,Lin D,Perrone-Bizzozero NI,Bustillo JR,Pearlson GD,Potkin SG,van Erp TGM,Macciardi F,Ehrlich S,Ho BC,Sponheim SR,Wang L,Stephen JM,Mayer AR,Hanlon FM,Jung RE,Clementz BA,Keshavan MS,Gershon ES,Sw

更新日期：2019-01-01 00:00:00

abstract：:The original CHoice of Outcome In Cbt for psychosEs (CHOICE) measure was designed in collaboration with experts by experience as a patient-reported "Psychological Recovery" outcome measure for cognitive-behavioral therapy for psychosis (CBTp). A short version (CHOICE-SF) was developed to use as a brief outcome measure...

journal_title：Schizophrenia bulletin

authors： Webb R,Bartl G,James B,Skan R,Peters E,Jones AM,Garety P,Kuipers E,Hayward M,Greenwood K

更新日期：2020-11-20 00:00:00

abstract：:Pharmacologic agents currently used or being studied for the treatment of schizophrenia are reviewed. Neuroleptic medications are still the mainstay of treatment, but recent studies suggest new approaches to dosage and to the treatment of acute psychosis. Lithium is beneficial in psychotic illnesses with acute onset a...

journal_title：Schizophrenia bulletin

authors： Donaldson SR,Gelenberg AJ,Baldessarini RJ

更新日期：1983-01-01 00:00:00

abstract：:The article that follows is part of the Schizophrenia Bulletin's ongoing First Person Accounts series. We hope that mental health professionals--the Bulletin's primary audience--will take this opportunity to learn about the issues and difficulties confronted by consumers of mental health care. In addition, we hope tha...

journal_title：Schizophrenia bulletin

authors： Bowden WD

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The homicide of strangers by people with psychosis, referred to here as "stranger homicides," are rare and tragic events that generate adverse publicity for mental health services and have resulted in significant changes in mental health policy and law. AIM:To estimate the incidence of stranger homicides, u...

journal_title：Schizophrenia bulletin

authors： Nielssen O,Bourget D,Laajasalo T,Liem M,Labelle A,Häkkänen-Nyholm H,Koenraadt F,Large MM

更新日期：2011-05-01 00:00:00

abstract：:The psychometric high-risk strategy represents a useful methodologic adjunct to the traditional genetic high-risk research approach in the study of the etiology and development of schizophrenia. During the past 15 years, considerable research activity has focused on psychometrically identified individuals hypothesized...

journal_title：Schizophrenia bulletin

authors： Lenzenweger MF

更新日期：1994-01-01 00:00:00

abstract：:The rate of substance-use disorders in patients with mental illnesses within the psychotic spectrum, such as schizophrenia, schizoaffective disorder, and bipolar disorder, is higher than the rate observed in the general population and is associated with significant morbidity and mortality. Although there are currently...

journal_title：Schizophrenia bulletin

authors： Petrakis IL,Nich C,Ralevski E

更新日期：2006-10-01 00:00:00

abstract：:Does the McFarlane et al study provide a model for practical trials? Unfortunately, not. The methodological problems are here reviewed and used as a springboard to set out methodological criteria that might define such a model. ...

journal_title：Schizophrenia bulletin

authors： Kraemer HC

更新日期：2015-01-01 00:00:00

abstract：:When fixed doses of haloperidol or perphenazine were used in two separate studies, we found that psychotic males with a prior history of psychotogenic drug use had a poorer early neuroleptic response even in the early stages of their psychotic disorder than psychotic males who had not previously used significant amoun...

journal_title：Schizophrenia bulletin

authors： Bowers MB Jr,Mazure CM,Nelson JC,Jatlow PI

更新日期：1990-01-01 00:00:00

abstract：Objective:A proinflammatory imbalance in the tumor necrosis factor (TNF) system may contribute to the pathogenesis of schizophrenia (SCZ) and bipolar disorders (BDs) and related comorbidities. We investigated the relative distribution of TNF-related molecules in blood and dorsolateral prefrontal cortex (DLPFC) in these...

journal_title：Schizophrenia bulletin

authors： Hoseth EZ,Ueland T,Dieset I,Birnbaum R,Shin JH,Kleinman JE,Hyde TM,Mørch RH,Hope S,Lekva T,Abraityte AJ,Michelsen AE,Melle I,Westlye LT,Ueland T,Djurovic S,Aukrust P,Weinberger DR,Andreassen OA

更新日期：2017-07-01 00:00:00

abstract：:The apparent neglect of neuropsychologic deficits in schizophrenia as the basis for therapeutic intervention, together with only isolated attempts at remediating them, probably reflect the nature of impairments, the functional significance of which is uncertain. A critique of the limitations inherent in the appealing ...

journal_title：Schizophrenia bulletin

authors： Hogarty GE,Flesher S

更新日期：1992-01-01 00:00:00

abstract：:Traditional psychiatric treatment approaches have not been very successful with the "revolving door patient." A variety of findings suggest that the social network, as opposed to the individual patient, may be a more viable locus for intervention. A conceptual review and analysis of the literature reveals two construc...

journal_title：Schizophrenia bulletin

authors： Morin RC,Seidman E

更新日期：1986-01-01 00:00:00

abstract：:The author reviews a number of studies which have shown that the overall mortality among patients with schizophrenia is about twice that in the general population. The highest excess mortality is found in suicide and violent death, but there seems to be an increased mortality also in cardiovascular disorders. Whether ...

journal_title：Schizophrenia bulletin

authors： Allebeck P

更新日期：1989-01-01 00:00:00