The content and structure of schizotypy: a study using confirmatory factor analysis.

abstract：:Little is known about the neurobiological factors that determine functional outcome in people at high risk for psychosis. We use multimodal neuroimaging to investigate whether cortical responses during a cognitive task and thalamic glutamate levels were associated with subsequent functional outcome. Sixty subjects par...

journal_title：Schizophrenia bulletin

authors： Allen P,Chaddock CA,Egerton A,Howes OD,Barker G,Bonoldi I,Fusar-Poli P,Murray R,McGuire P

更新日期：2015-03-01 00:00:00

abstract：:The two indices that have been proposed for quantifying the accuracy of smooth-following eye movements are shown to be interchangeable. This algebraic fact will permit comparability of values between laboratories only if workers who employ the signal-to-noise ratio (S/N) as their index measure S and N as the total sig...

journal_title：Schizophrenia bulletin

authors： Lykken DT,Iacono WG,Lykken JD

更新日期：1981-01-01 00:00:00

abstract：:Schizophrenia elevates the risk for aggressive behavior and violent crime, and different approaches have been used to manage this problem. The results of such treatments vary. One reason for this variation is that aggressive behavior in schizophrenia is heterogeneous in origin. This heterogeneity has usually not been ...

journal_title：Schizophrenia bulletin

authors： Volavka J,Citrome L

更新日期：2011-09-01 00:00:00

abstract：:In addition to introducing the six articles joined by our thematic outlook, this article addresses the importance of subcortical structures as they may be related to information processing and the life experience of schizophrenic patients. This is a heuristic exercise aimed at bridging the conceptual gaps between clin...

journal_title：Schizophrenia bulletin

authors： Patterson T

更新日期：1987-01-01 00:00:00

abstract：:Social cognitive deficits are associated with psychotic symptoms, but the nature of this association remains unknown. This study uses a genetically sensitive cross-trait cross-sibling design to investigate the nature of the overlap between both phenotypes. A sample of 1032 patients, 1017 of their healthy siblings, and...

journal_title：Schizophrenia bulletin

authors： Fett AK,Maat A,GROUP Investigators.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Schizophrenia is associated with excess physical comorbidity. Yet, to our knowledge, large studies are lacking on the associations with somatic diseases before the onset of schizophrenia. The authors conducted a nationwide study of the full spectrum of treated somatic diseases before the first diagnosis of sc...

journal_title：Schizophrenia bulletin

authors： Sørensen HJ,Nielsen PR,Benros ME,Pedersen CB,Mortensen PB

更新日期：2015-03-01 00:00:00

abstract：:Cognitive-behavioral therapy for psychosis is described. It draws on the cognitive models and therapy approach of Beck and colleagues, combined with an application of stress-vulnerability models of schizophrenia and cognitive models of psychotic symptoms. There is encouraging evidence for the efficacy of this approach...

journal_title：Schizophrenia bulletin

authors： Garety PA,Fowler D,Kuipers E

更新日期：2000-01-01 00:00:00

abstract：:Psychiatric research, including the search for predisposing genes, has tended to proceed under the assumptions that schizophrenia and bipolar disorder, as defined in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and International Statistical Classification of Diseases, 10th Revision, are discr...

journal_title：Schizophrenia bulletin

authors： Owen MJ,Craddock N,Jablensky A

更新日期：2007-07-01 00:00:00

abstract：:To understand the biological significance of a decreased platelet MAO activity in schizophrenia, it is important to answer many questions about the basic molecular properties of the enzyme. The past decade has witnessed a huge expansion of research in this area which has provided some of these answers. A wide variety ...

journal_title：Schizophrenia bulletin

authors： Edwards DJ

更新日期：1980-01-01 00:00:00

abstract：:Despite NIMH efforts to facilitate the study of women and minorities in federally funded schizophrenia research, there is a significant lack of information about race differences in brain morphology and neuropsychological function in schizophrenia. A review of three major psychiatric journals between 1994 and 1996 rev...

journal_title：Schizophrenia bulletin

authors： Lewine RR,Caudle J

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Working memory (WM) deficit is a key feature of schizophrenia that relates to a generalized neural inefficiency of extensive brain areas. To date, it remains unknown how these distributed regions are systemically organized at the connectome level and how the disruption of such organization brings about the W...

journal_title：Schizophrenia bulletin

authors： Yang J,Pu W,Wu G,Chen E,Lee E,Liu Z,Palaniyappan L

更新日期：2020-07-08 00:00:00

abstract：:Educating the public that mental illness is a brain disease is a popular strategy for combating mental illness stigma. Evidence suggests that while such an approach reduces blame for mental illness, it may unintentionally exacerbate other components of stigma, particularly the benevolence and dangerousness stigmas. Co...

journal_title：Schizophrenia bulletin

authors： Corrigan PW,Watson AC

更新日期：2004-01-01 00:00:00

abstract：:Neuroleptic drugs block brain dopamine receptors and are effective in treating psychoses of diverse origins. This finding has become a cornerstone of the dopamine theory of schizophrenia, but clinical studies relating schizophrenia, per se, to brain dopamine metabolism have ranged from controversial to negative. This ...

journal_title：Schizophrenia bulletin

authors： Maas JW,Bowden CL,Miller AL,Javors MA,Funderburg LG,Berman N,Weintraub ST

更新日期：1997-01-01 00:00:00

abstract：:Changed synapse density has been suggested to be involved in the altered brain connectivity underlying schizophrenia (SCZ) pathology. However, postmortem studies addressing this topic are heterogeneous and it is not known whether changes are restricted to specific brain regions. Using meta-analysis, we systematically ...

journal_title：Schizophrenia bulletin

authors： Berdenis van Berlekom A,Muflihah CH,Snijders GJLJ,MacGillavry HD,Middeldorp J,Hol EM,Kahn RS,de Witte LD

更新日期：2020-02-26 00:00:00

abstract：:Recent studies provide considerable evidence that schizophrenia and bipolar disorder may share overlapping etiologic determinants. Identifying disease-related genetic effects is a major focus in schizophrenia and bipolar disorder research, with implications for clarifying diagnosis and developing specific treatments f...

journal_title：Schizophrenia bulletin

authors： Thaker G

更新日期：2008-07-01 00:00:00

abstract：:Given the rising costs of health care and the decrease in public expenditures on mental health care, policy-makers and program managers must identify cost-effective approaches for treating severely mentally ill patients. During the last year, there have been two major cost-effectiveness studies implemented in Californ...

journal_title：Schizophrenia bulletin

authors： Hu TW,Jerrell J

更新日期：1991-01-01 00:00:00

abstract：UNLABELLED:We aimed to discover whether metabolic complications of schizophrenia (SZ) are present in first episode (FE) and unmedicated (UM) patients, in comparison with patients established on antipsychotic medication (AP). METHOD:A systematic search, critical appraisal, and meta-analysis were conducted of studies to...

journal_title：Schizophrenia bulletin

authors： Mitchell AJ,Vancampfort D,De Herdt A,Yu W,De Hert M

更新日期：2013-03-01 00:00:00

abstract：:With on exception, previous studies examining the familial relationship between schizotypal personality disorder (SPD) and schizophrenia have compared rates of SPD in relatives of probands with schizophrenia versus control probands. In the Roscommon Family Study, an epidemiologically based family study of major psychi...

journal_title：Schizophrenia bulletin

authors： Kendler KS,Walsh D

更新日期：1995-01-01 00:00:00

abstract：:We report a 25-year followup of a group of 50 children at genetic risk for schizophrenia (by virtue of having a parent with the disorder) and 50 matched controls. The children who eventually developed schizophrenia spectrum disorders, including schizophrenia, were identifiable by cognitive-psychophysiological, neuroin...

journal_title：Schizophrenia bulletin

authors： Mirsky AF,Kugelmass S,Ingraham LJ,Frenkel E,Nathan M

更新日期：1995-01-01 00:00:00

abstract：:While many who hear auditory hallucinations (AHs) experience them as unpleasant, some do not. Little is known about the correlates of AHs that are not unpleasant, or of the characteristics of those who hear them. To better understand this symptom, we used a comprehensive structured interview schedule to study 199 subj...

journal_title：Schizophrenia bulletin

authors： Copolov DL,Mackinnon A,Trauer T

更新日期：2004-01-01 00:00:00

abstract：:The author reviews a number of studies which have shown that the overall mortality among patients with schizophrenia is about twice that in the general population. The highest excess mortality is found in suicide and violent death, but there seems to be an increased mortality also in cardiovascular disorders. Whether ...

journal_title：Schizophrenia bulletin

authors： Allebeck P

更新日期：1989-01-01 00:00:00

abstract：:The traditional view of life events is that the crucial factor is the number which occur within a defined time period. This was examined as part of a 2-year, prospective, longitudinal study of prospective, longitudinal study of 518 people, each of whom was interviewed every 6 months with Holmes and Rahe's Recent LIfe ...

journal_title：Schizophrenia bulletin

authors： Streiner DL,Norman GR,McFarlane AH,Roy RG

更新日期：1981-01-01 00:00:00

abstract：:Delusions, the fixed false beliefs characteristic of psychotic illness, have long defied understanding despite their response to pharmacological treatments (e.g., D2 receptor antagonists). However, it can be challenging to discern what makes beliefs delusional compared with other unusual or erroneous beliefs. We sugge...

journal_title：Schizophrenia bulletin

authors： Feeney EJ,Groman SM,Taylor JR,Corlett PR

更新日期：2017-03-01 00:00:00

abstract：:As part of an open clinical trial currently underway at the Max Planck Institute of Psychiatry in Munich, the feasibility of behavioral family management (Falloon et al. 1984) for schizophrenia in combination with two different neuroleptic medication strategies was investigated. The treatment approaches were psychoedu...

journal_title：Schizophrenia bulletin

authors： Wiedemann G,Hahlweg K,Hank G,Feinstein E,Müller U,Dose M

更新日期：1994-01-01 00:00:00

abstract：:Secondary sources continue to cite a one-page preliminary note about the Michigan State Psychotherapy Project, ignoring fuller reports in print. Relevant experience and training are critical to quality control of psychotherapy in schizophrenia research. This investigation is unique in that "experienced" meant that the...

journal_title：Schizophrenia bulletin

authors： Karon BP

更新日期：1978-01-01 00:00:00

abstract：:Similarities in clinical course, age of onset, geographical distribution, and immunological responses of patients with schizophrenia and multiple sclerosis (MS) suggest that these two common illnesses of young adults may belong to a similar class of disorders. This review examines some of the similarities and differen...

journal_title：Schizophrenia bulletin

authors： Stevens JR

更新日期：1988-01-01 00:00:00

abstract：:Distinguishing between brain-damaged and schizophrenic patients remains a significant clinical problem. However, substantive and methodological difficulties have led to discouragement and consequent loss of interest in this area of differential diagnosis. Several models for making this distinction were proposed: cogni...

journal_title：Schizophrenia bulletin

authors： Goldstein G

更新日期：1978-01-01 00:00:00

abstract：:Designs of clinical trials that will permit evaluation of independent, additive, and interactive effects of drugs and psychosocial treatments are described. The central feature of such designs is that they incorporate control conditions for both classes of treatment. Data from the articles in this issue are drawn upon...

journal_title：Schizophrenia bulletin

authors： Schooler NR

更新日期：1980-01-01 00:00:00

abstract：:Phenomenological research suggests that pure manic and depressive states are less common than mixtures of the two and that the two poles of mood are characterized by opposite ways of experiencing time. In mania, the subjective experience of time is sped up and in depression it is slowed down, perhaps reflecting differ...

journal_title：Schizophrenia bulletin

authors： Ghaemi SN

更新日期：2007-01-01 00:00:00

abstract：:There is an increasing emphasis on identifying individuals with schizophrenia earlier and earlier in their disease process, with the assumption that earlier identification translates into earlier treatment, which translates into improved outcome. Unfortunately, one age cohort, children under 13 years of age, have been...

journal_title：Schizophrenia bulletin

authors： Ross RG,Schaeffer J,Compagnon N,Heinlein S,Beresford C,Farley G

更新日期：2003-01-01 00:00:00