Abstract：
:The clinical disappearance of the murmur of rheumatic mitral regurgitation after period of time has been documented by many researchers. However no studies have related the disappearance of the murmur with the functional or anatomical state of the mitral valve. This study was done to elucidate the mitral valve status using doppler and color coded echocardiography among those children who have lost their apical pansystolic murmur on auscultation following a documented attack of rheumatic fever. The study sample consisted of 51 patients including 31 patients in whom the murmur has disappeared (group I), and 20 patients with persistent isolated mitral regurgitation (group II). Patients of group I had significantly lower grades of murmur intensity, lower incidence of cardiomegaly, and had no heart failure in the initial attack. They were more compliant with prophylaxis and had less recurrences than patients of group II. The murmur disappeared in patients of group I from 1/2 to 14 years after the initial attack. Echocardiography revealed that such patients had a normal mitral valve apparatus, and a normal heart size and function. Only 5 patients of this group had a significant regurgitant jet demonstrated by colour doppler. We concluded that recovery of the mitral valve and return of cardiac functions to normal is possible in patients who had mitral regurgitation following rheumatic fever. Some of them may still have an inaudible mild regurgitation. Patients who have lost their murmur may be allowed to exercise freely, yet penicillin prophylaxis should not be discontinued.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Kassem AS,el-Walili TM,Zaher SR,Ayman Mdoi
10.1007/BF02825126keywords:
subject
Has Abstractpub_date
1995-11-01 00:00:00pages
717-23issue
6eissn
0019-5456issn
0973-7693journal_volume
62pub_type
杂志文章abstract：:A two-and-a-half-year-old male child presented with recurrent attacks of intractable vomiting, psychomotor retardation since 14 months of age. He had also lower cranial nerve palsy and corticospinal involvement. Magnetic resonance imaging had shown multiple well circumscribed areas of hypointusity in T1 weighted image...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02730822
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of folic acid supplementation on seizure control in folate deficient children receiving long term antiepileptic therapy. METHODS:In a prospective interventional study, 140 children between age group 6 mo to 180 mo fulfilling the inclusion criteria were enrolled in study group, from Oct...
journal_title：Indian journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/s12098-018-2608-1
更新日期：2018-07-01 00:00:00
abstract：:Effective management of tuberculosis (TB) in children and important data of disease burden continue to rely on a clinical approach to diagnosis, as diagnosis of childhood TB is not confirmed in the majority. Many diagnostic scoring systems have been developed to aid with diagnosis. This article reviews the use and eva...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-010-0307-7
更新日期：2011-03-01 00:00:00
abstract：:Conducting economic evaluation alongside clinical trials is an efficient way of getting valid and reliable information with minimum assumptions made during data collection. However, design of a randomised control trial (RCT) takes away several of the real world situations, the variations in resource utilisation, their...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02820689
更新日期：2000-05-01 00:00:00
abstract：OBJECTIVE:To find out various life stressors of adolescents, coping strategies adopted by them and the impact of stress on adolescent mental health. METHODS:A descriptive, cross sectional study was conducted in the schools in south zone of Delhi, capital city of the country. Data was collected on 360 adolescents betwe...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-015-1710-x
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:To find out whether gDNA methylation can be used as a diagnostic/prognostic method for neonatal sepsis. METHODS:The study was conducted in the neonatal division of a tertiary care referral hospital. Fifty one newborns as cases and thirty seven newborns as controls were enrolled in the study. Using 5-mC DNA E...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-014-1574-5
更新日期：2015-04-01 00:00:00
abstract：:Glanzmann's thrombasthenia (GT) is an uncommon cause of bleeding in children. We diagnosed two siblings as having GT on the basis of flow cytometric studies. Both had cutaneous bleedings and epistaxis since early childhood. Hematological investigations revealed prolonged bleeding time and a normal platelet count. Both...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02723255
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of temporal artery thermometer in febrile and hypothermic neonates in comparison to axillary thermometer. METHODS:It was a cross sectional observational study. Study participants included 210 neonates admitted in neonatal intensive care unit of a tertiary care teaching hospital, divide...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-016-2259-z
更新日期：2017-03-01 00:00:00
abstract：:Major areas in which innovative approaches in medical education have been tried include student selection, learning strategies, and community orientation. It is relatively easier to implement innovations in a new institution. In established medical schools, running two simultaneous curricula tracks, the traditional an...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02751045
更新日期：1993-11-01 00:00:00
abstract：:Kawasaki disease (KD) is a systemic necrotizing vasculitis affecting medium and small sized arteries. The diagnosis is based entirely on recognition of a typical sequence of clinical features. Detection of any one clinical feature does not have any diagnostic significance. We report an uncommon case of Kawasaki diseas...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02722603
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:To determine pulmonary function abnormalities in children with Sickle Cell Disease (SCD) from Western India. METHODS:In this cross sectional study conducted at Surat, Gujarat, India; equal number of age and gender matched children i.e., 99 in the age group of 6-18 y was recruited in case (children with SCD) ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-016-2065-7
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVE:To conduct a community survey to understand the prevalence and type of developmental delay/disability among a representative state wide community sample of children below 3 y. METHODS:A state wide community based cross sectional survey was done with the help of the Integrated Child Development Services (ICDS...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-014-1579-0
更新日期：2014-12-01 00:00:00
abstract：:Medical bioethics has developed as a new field of study in the US in the past quarter decade, focusing upon the moral principles of autonomy, beneficence, nonmaleficence, and justice. These principles may, however, reflect biases in American culture, rather than a truly universal approach to ethical problems in medici...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02845196
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y. METHODS:This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from Decem...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-019-03032-0
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVES:To determine the incidence, pattern, causality, preventability, severity and predictors of adverse drug reactions (ADRs) in pediatric population. METHODS:It was a prospective, observational study that included patients of either sex, of any age treated in the pediatric wards of a tertiary care hospital. Stu...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-015-2002-1
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVES:To determine the incidence, etiology and outcome of Cardiorenal syndrome (CRS) in hospitalized children. METHODS:A prospective cohort study was carried out in 242 children between 6 mo to 18 y of age hospitalized with primary cardiac, renal or any systemic disorder at a tertiary care center in India. The pr...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-017-2307-3
更新日期：2017-06-01 00:00:00
abstract：:Psychosocial and mental health problems are quite prevalent among adolescent worldwide, some data reporting up to 20% of adolescents having such problems. A number of risk factors, familial, individual and societal, have been indentified as contributing to these problems in adolescents. There are also many factors, su...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723793
更新日期：2003-10-01 00:00:00
abstract：: ...
journal_title：Indian journal of pediatrics
pub_type： 信件
doi：10.1007/s12098-018-2702-4
更新日期：2019-01-01 00:00:00
abstract：:During the four years period from 1988 to 1991, 50 pediatric patients were diagnosed to have bacterial meningitis, out of a total number of 9057 pediatric admissions at Qatif Central Hospital, Qatif, Saudi Arabia, and 82% were less than two years of age. The causative organisms were isolated in 27 (54%) patients. The ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02859407
更新日期：1992-11-01 00:00:00
abstract：:There is increased interest in the surgical management of epilepsy in children in the last decade or two. The plasticity of the developing brain and realization of the deleterious effects of uncontrolled seizures on the brain have prompted earlier surgery where indicated. All patients with uncontrolled partial seizure...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:Antiperistaltic appendiceal conduit based on its vascular pedicle was used as hepaticoporto-appendico-jejunostomy (HAJ) in 9 infants with advanced stage of biliary atresia. Operative procedure was simple and less time consuming. The postoperative cholangitis was conspicuously absent, possibly due to the role played by...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02722419
更新日期：1989-07-01 00:00:00
abstract：:Necrotizing enterocolitis (NEC), an inflammatory bowel necrosis of preterm infants, is the most common gastrointestinal emergency and a major cause of morbidity and mortality in these infants. In this article, the authors review the pathophysiology and clinical presentation of NEC and provide a critical appraisal of t...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-014-1388-5
更新日期：2014-05-01 00:00:00
abstract：:The present analytic study was planned to study the impact of overweight and obesity on glucose tolerance in adolescents. Thirty overweight (BMI analogue ≥ 25-29.9 kg/m(2)) and 30 obese (BMI analogue ≥ 30 kg/m(2)) adolescents were included as cases and 30 healthy age and sex matched adolescents comprised the contro...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-011-0456-3
更新日期：2011-11-01 00:00:00
abstract：:Non-Specific Aorto-arteritis or Takayasu's arteritis (TA) is a chronic inflammatory disease of the aorta and its major branches which either presents with constitutional symptoms in its active phase or with steno-occlusive symptoms in the healing phase. In children, it is an aggressive disease and often lethal. Conges...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02722657
更新日期：2002-06-01 00:00:00
abstract：:Gastro-esophageal reflux (GER) is a common occurrence in newborns and a cause of anxiety to most parents. This physiological process needs to be closely differentiated from pathological reflux. The clinical signs in infants are generally non-specific which makes the distinction difficult. The diagnostic options in inf...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-014-1535-z
更新日期：2015-01-01 00:00:00
abstract：:Nephrotic syndrome in children is a common recurrent disease. Most of the cases are due to minimal change disease with a favourable outcome. More than 90% of children with minimal change disease respond to corticosteroid therapy (steroid sensitive nephrotic syndrome). 40-60% experience frequent relapses or have steroi...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02724388
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVE:To assess the prevalence of peripheral neuropathy in HIV infected children (>5 y) receiving stavudine-based combination anti-retroviral treatment (ART) for more than 3 mo in a cross-sectional study. METHODS:History, detailed neurological examination and nerve conduction studies were performed. RESULTS:Forty...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-014-1477-5
更新日期：2015-02-01 00:00:00
abstract：:The magnitude of work and existence of multiple agencies makes the task of providing school health services to all pupils of the State of Delhi with uniform standards, a very complex job. The present article looks at the matter from the provider's end, illustrates the structural and organizational features of various ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02723659
更新日期：2000-03-01 00:00:00
abstract：:We studied the auditory brainstem responses of 50 high risk neonates from NICU and compared with those of 25 normal neonates in order to determine the percentage of significant auditory impairment in NICU and correlated it to various risk factors. Infants with the risk factors of low birth weight, hyperbilirubinemia, ...
journal_title：Indian journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/BF02725499
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:To find out correlation between serum anti-tissue transglutaminase immunoglobulin-A (tTGA) levels and Marsh grading on duodenal histopathology in Celiac disease (CD). METHODS:In a prospective cohort study, a total of 52 symptomatic patients between age group of 2-18 y were enroled. All enroled patients were ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-017-2323-3
更新日期：2017-07-01 00:00:00
