Steroid sensitive nephrotic syndrome.

Abstract:

:Nephrotic syndrome in children is a common recurrent disease. Most of the cases are due to minimal change disease with a favourable outcome. More than 90% of children with minimal change disease respond to corticosteroid therapy (steroid sensitive nephrotic syndrome). 40-60% experience frequent relapses or have steroid dependence. These children require frequent corticosteroid therapy and/or immunomodulators or treatment with immunosuppressants, and are at high risk of cumulative steroid toxicity and side effects of cytotoxic therapy. Children with frequent relapses or steroid dependence should be managed in consultation with a pediatric nephrologist. Despite relapsing course, progression of minimal change nephrotic syndrome to end stage renal disease is extremely rare.

journal_name

Indian J Pediatr

authors

Nanjundaswamy HM,Phadke KD

doi

10.1007/BF02724388

keywords:

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

1059-63

issue

12

eissn

0019-5456

issn

0973-7693

journal_volume

69

pub_type

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