Abstract:
:Juvenile dermatomyositis and juvenile scleroderma are rare multisystem autoimmune disorders. Although they share some pathognomonic hallmarks with adult onset myositis or scleroderma, there are significant differences in presentation, characteristics and associated features when the diseases present in childhood. In view of this, and the rarity of the conditions, it is important for care to be led by teams with expertise in pediatric rheumatology conditions. Prognosis has improved significantly in the West; likely due to early diagnosis and aggressive treatment with immunosuppressive medications. However, this trend is not replicated in the developing world. Early recognition of these diseases is crucial to achieve rapid and sustained remission and prevent disease or medication associated complications. This article aims to provide a practical overview for recognition, diagnosis and treatment of these conditions.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
McCann LJ,Pain CEdoi
10.1007/s12098-015-1907-zsubject
Has Abstractpub_date
2016-02-01 00:00:00pages
163-71issue
2eissn
0019-5456issn
0973-7693pii
10.1007/s12098-015-1907-zjournal_volume
83pub_type
杂志文章,评审abstract::Celiac disease may present as a cryptogenic liver disorder being found in 5-10 % of patients with a persistent and cryptogenetic elevation of serum aminotransferase activity. In fact, a wide spectrum of liver injuries in children and adults may be related to CD and in particular: (1) a mild parenchymal damage characte...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02790391
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y. METHODS:This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from Decem...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-019-03032-0
更新日期:2019-12-01 00:00:00
abstract::Bone marrow transplantations have a definite role in treatment of leukemias and lymphomas. In acute myeloid leukemia and CML an allogeneic transplant using an HLA identical donor certainly provides a far superior survival than chemotherapy. Patients with Ph' chromosome need to be transplanted in first remission if a s...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02751432
更新日期:1993-07-01 00:00:00
abstract::Low hemoglobin and low MCHC levels were indicative of high incidence of iron deficiency in preschool children. The extent of iron deficiency as assessed by serum ferritin and free erythrocyte protoporphyrin showed a different trend. While FEP levels were highly suggestive of extensive iron deficiency (in 40-45% of chi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02759985
更新日期:1992-03-01 00:00:00
abstract::It is common for primary care physicians to be faced with children with hematological disorders in everyday practice. The article seeks to provide realistic information for the first-contact physician in handling common hematological diseases in children. Practical step-wise approach to understanding and investigating...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1159-8
更新日期:2014-01-01 00:00:00
abstract::The authors report a case of intra-abdominal migration of a Kirschner wire from the left hip to the right lobe of the liver in a 5-year-old child. The wire was used for stabilization of the left hip after open reduction for neglected unreduced congenital dislocation of the left hip. The migrated wire was removed by la...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02763056
更新日期:2006-12-01 00:00:00
abstract::Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral P...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0190-2
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To investigate correlations between anthropometrics and body composition with bone parameters of the whole-body and lumbar spine in non-obese and obese Thai female adolescents. METHODS:This study was performed in 135 female adolescents aged 15 to 18 y enrolled in secondary schools in southern Thailand. Subje...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2422-1
更新日期:2017-12-01 00:00:00
abstract::Due to changing characteristics of infective endocarditis in the past two decades, we, retrospectively analysed 28 cases of infective endocarditis in children of age less than 15 years at Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar from December, 1983 to November, 1993. The incidence of disease was o...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02845245
更新日期:1996-03-01 00:00:00
abstract::Allan-Herndon-Dudley Syndrome (AHDS) is a rare X-linked disorder caused by mutation in the gene encoding the monocarboxylate transporter-8. Abnormal transport function is reflected by elevated free T3 and decreased free T4 levels along with clinical features characterized by neurological abnormalities including global...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:Screen for Child Anxiety Related Emotional Disorders (SCARED), a measure found useful in different settings and cultures has not been validated in the subcontinent. This study validated this measure for identifying Anxiety Disorder (AD) among adolescents in an Indian community context. METHODS:Five hundred a...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1233-2
更新日期:2013-11-01 00:00:00
abstract::Malaria is essentially a local and focal disease since its transmission depends greatly on local eco-environmental conditions. In India, the incidence of total malaria cases has been contained to around 2-3 million cases per year. However, with the occurrence of outbreaks in different parts of the country since 1994, ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02727167
更新日期:1999-07-01 00:00:00
abstract::Advances in immunosuppressive treatment as well as better monitoring and control of acute rejection have brought intestinal transplantation (ITx) into the realm of standard treatment for permanent intestinal failure. The results from the intestinal Transplant International Registry (www.intestinaltransplant.org) indic...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02724317
更新日期:2003-09-01 00:00:00
abstract::Fainting attack or syncope in children is a common occurrence, with vasovagal syncope being the commonest cause for majority of pediatric syncope. The aim of emergency room evaluation is not to miss the rare serious underlying disorder causing syncope. A complete detailed history of the event followed by physical exam...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0497-7
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:The present study was conducted to evaluate physical growth and nutritional status of 214 school-going girls ranging in age from 5 to 12 years of rural area in Pauri Garhwal district of Uttaranchal. METHODS:Physical growth was evaluated using eleven standard anthropometric measurements viz., height, body wei...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02724181
更新日期:2005-07-01 00:00:00
abstract::Cryptosporidium is an intestinal protozoa known to cause diarrhea in animals and more recently has been recognised as a cause of diarrhea in humans. The present study was designed to determine the prevalence of cryptosporidium as a cause of diarrhea in children. Faecal samples of 180 children admitted to the hospital ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02749728
更新日期:1989-01-01 00:00:00
abstract::We report here a 3 month old child with empyema thoracis, who developed complications of diaphragmatic palsy and Horner's syndrome. These complications of empyema thoracis have not been reported earlier. We discuss the possible mechanisms for these complications. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02859293
更新日期:2006-10-01 00:00:00
abstract::Although seasonal trends in incidence and diagnosis of pediatric cancers have been widely investigated, the results have been inconclusive. A consistent seasonal trend may possibly provide etiological insights into pediatric cancers. This study aims to determine if there is a seasonal variation in cancer diagnoses in ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2561-4
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of R501X mutation of Filaggrin gene in children with allergic diseases. METHODS:Ninety patients recruited from Allergy and Asthma clinic of Advanced Pediatric Centre, PGIMER, Chandigarh and 81 healthy controls from local schools matched for age, gender and BMI were enroled in the ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03231-0
更新日期:2020-08-01 00:00:00
abstract::Hitherto poor outcomes, paucity of data and heterogeneity in International approach to Pediatric NHL (Non-Hodgkin Lymphoma) prompted the need for guidelines for Indian population with vast variability in access, affordability and infrastructure across the country. These guidelines are based on consensus among the expe...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-017-2318-0
更新日期:2017-05-01 00:00:00
abstract::Respiratory disease in childhood is common but not all children presenting to the paediatrician have an underlying organic cause for their symptoms. This article reviews the spectrum of non-organic somatization disorders that might be encountered and advises about the diagnosis and treatment of habit cough, laryngeal ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726188
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVES:To compare early child care practices at home as possible risk factors among children between 2 and 6 y of age with autism and a control group of normal children without any symptom of autism, presenting at the well-baby/immunization clinic. METHODS:This case control study was undertaken at the autism clini...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1602-5
更新日期:2014-12-01 00:00:00
abstract::To study pulmonary function tests (PFT) in multiple transfusion recipient thalassemics, PFTs were done for 30 thalassemics and 20 matched controls. Confirmed cases of thalassemia on regular transfusion therapy were the subject of study. Apart from history and physical examination of the thalassemics, serum ferritin es...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723198
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVES:To analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective indigenous diet for management of this disorder. METHODS:This is a single-centre retrospective study. Fifteen patients from 14 kindreds with severe hypertriglyceridemia (more...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03305-z
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:To determine the possible risk factors for severe acute malnutrition (SAM) in children below 5 y admitted in a hospital in north India. METHODS:This case-control study was conducted in a medical college hospital in children below 5 y of age. All cases of SAM (diagnosed as per WHO definition) between 6 and 59...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1127-3
更新日期:2014-08-01 00:00:00
abstract::Intolerance to foods which contain lactose can cause a range of intestinal and systemic symptoms. These symptoms are caused by Lactase deficiency which is encoded by a single gene (LCT) of ≈ 50 kb located on chromosome 2q21. In some food items, lactose has been missed because of "hidden" lactose due to inadequately la...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-014-1346-2
更新日期:2014-09-01 00:00:00
abstract::The magnitude of work and existence of multiple agencies makes the task of providing school health services to all pupils of the State of Delhi with uniform standards, a very complex job. The present article looks at the matter from the provider's end, illustrates the structural and organizational features of various ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723659
更新日期:2000-03-01 00:00:00
abstract::Vaccination is one of the most cost effective methods of prevention of diseases without even raising the socioeconomic status of the community. Small pox eradication from the world is the perfect example of the role of mass vaccination of the entire community of the universe. India is feeling proud to be polio free fo...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0957-8
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of culture-confirmed cholera in patients with acute dehydrating diarrhea, at a tertiary care center in north India, during a 6-month period from March to August, 2006. METHODS:We studied 145 children, who presented to the pediatric emergency services of a tertiary care teaching hos...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0009-1
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To quantitatively summarize the evidence from observational studies on the relation between pediatric asthma and food allergy. METHODS:A literature search was conducted in Medline and EMBASE (August 2016). Two independent reviewers appraised the studies and extracted the estimates of interest. Methodological...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,meta分析
doi:10.1007/s12098-017-2326-0
更新日期:2017-08-01 00:00:00