Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy.

Abstract:

:Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral PP who presented with unilateral enlargement of the ovary and a recurrent autonomous ovarian cyst. No skin pigmentation or bone anomaly was noted. The patient was successfully treated with anastrozole, a highly selective aromatase inhibitor. No adverse reaction was noted. Anastrozole is a safe and tolerable drug especially used to suppress estrogen action.

journal_name

Indian J Pediatr

authors

Engiz O,Berberoglu M,Siklar Z,Bilir P,Ocal G

doi

10.1007/s12098-009-0190-2

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

950-1

issue

9

eissn

0019-5456

issn

0973-7693

journal_volume

76

pub_type

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