Abstract:
:Although seasonal trends in incidence and diagnosis of pediatric cancers have been widely investigated, the results have been inconclusive. A consistent seasonal trend may possibly provide etiological insights into pediatric cancers. This study aims to determine if there is a seasonal variation in cancer diagnoses in the pediatric population at the IWK Health Centre, a tertiary care center serving three Canadian provinces: Nova Scotia, New Brunswick, and Prince Edward Island. All pediatric cancer patients aged 0-20 y diagnosed from 1995 to 2015 at the center were included in this study. The annual data was divided into four seasonal periods (December to February, March to May, June to August, and September to November). The cancer diagnoses were categorized as leukemia, lymphoma, sarcoma, brain tumors, and miscellaneous. Seasonal variation was assessed by a harmonic function in a Poisson regression model. The amplitude of multiplicative change in the incidence rate caused by the seasonal variation is expressed as the incidence rate ratio (IRR). For all cancer diagnoses for the entire cohort of 1200 patients, the IRR was 1.03 [95% confidence interval (CI) 0.96-1.13]. None of the IRRs for the cancer groups indicated a statistically significant seasonality of cancer diagnosis: Leukemia 1.11 (95% CI 0.96-1.28); Lymphoma 1.17 (95% CI 0.93-1.47); Sarcoma 1.29 (95% CI 0.99-1.69); Brain tumors 1.16 (95% CI 0.97-1.38); Miscellaneous 1.09 (95% CI 0.93-1.27). The present study did not show a seasonal variation in the various cancer types in the pediatric population at the IWK.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Nurullah R,Kuhle S,Maguire B,Kulkarni Kdoi
10.1007/s12098-017-2561-4subject
Has Abstractpub_date
2018-09-01 00:00:00pages
785-787issue
9eissn
0019-5456issn
0973-7693pii
10.1007/s12098-017-2561-4journal_volume
85pub_type
杂志文章abstract:OBJECTIVE:Autopsy findings play an important role in prevention of perinatal and neonatal deaths. Therefore, we attempted to reveal demographic and forensic features of these deaths in Turkey. METHODS:We retrospectively reviewed autopsy reports for 184 cases of perinatal deaths released from Istanbul Forensic Medicine...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-008-0213-4
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To report our experience before and after implementation of pediatric rapid response team (RRT) in pediatric wards of a tertiary care hospital in Pakistan. METHODS:An audit of RRT activity from December 2007 to August 2008 was conducted and reviewed patient diagnoses at the time of call placement, interventi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0032-2
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To describe the clinical profile of Hand Foot and Mouth Disease (HFMD) like illness in a cluster of cases. METHODS:Children presenting with papulovesicular skin lesions with or without oral lesions were clinically examined, treated and followed up. RESULTS:Out of 21 cases, 18 (85.7%) were less than 3y and 1...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-016-2271-3
更新日期:2017-03-01 00:00:00
abstract::A 4 year-old girl had coxa vara, tibial bowing and hyperpigmented macules. The x-ray showed polyostotic fibrous dysplasia and evidence of rickets. Biochemical investigations confirmed hyperphosphaturic hypophosphatemic rickets. The literature has been reviewed. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02727183
更新日期:1999-07-01 00:00:00
abstract::Patients infected with the human immunodeficiency virus (HIV) commonly experience diarrhea at some time during their illness. A variety of enteric pathogens are identified in 50-80% of these patients, depending on the intensity of the diagnostic work-up that is done. In addition to the common enteric pathogens, severa...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02752359
更新日期:1999-01-01 00:00:00
abstract::The primary goal in the management of a child with urinary tract infection (UTI) is to prevent recurrence of UTI and acquired renal damage. Approximately 15% of children develop renal scarring after a first episode of febrile UTI. Vesico-ureteric reflux (VUR) is diagnosed in 30-40% of children imaged after first febri...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-017-2359-4
更新日期:2017-07-01 00:00:00
abstract::Cerebral Palsy (CP) is the most common chronic disability of childhood. The problems involved are complex; not only do these children have problems of mobility, but a plethora of associated problems [1]. A recent definition of CP includes secondary musculoskeletal problems [2]. The inclusion of this in the definition ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-015-1999-5
更新日期:2016-11-01 00:00:00
abstract::An 11-mo-old infant received 12.5 times the maximum therapeutic dose of amlodipine as a result of a medication error in lieu of amoxicillin. He presented with vomiting, lethargy, breathlessness, muffled heart sounds and progressed to hypotensive shock within three hours of admission. He received mechanical ventilation...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0861-2
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of peripheral neuropathy in HIV infected children (>5 y) receiving stavudine-based combination anti-retroviral treatment (ART) for more than 3 mo in a cross-sectional study. METHODS:History, detailed neurological examination and nerve conduction studies were performed. RESULTS:Forty...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1477-5
更新日期:2015-02-01 00:00:00
abstract::Malaria is essentially a local and focal disease since its transmission depends greatly on local eco-environmental conditions. In India, the incidence of total malaria cases has been contained to around 2-3 million cases per year. However, with the occurrence of outbreaks in different parts of the country since 1994, ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02727167
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y. METHODS:This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from Decem...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-019-03032-0
更新日期:2019-12-01 00:00:00
abstract::India currently has an infant mortality rate (IMR) of 73 and aims to reach 60 per 1000 live births by 2000 A.D. The "at risk" approach which has been traditionally used for Maternal and Child Health services could help to reduce costs. The main objective of the study was to identity socio-demographic "risk factors" at...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02859456
更新日期:2000-06-01 00:00:00
abstract:: ...
journal_title:Indian journal of pediatrics
pub_type: 社论
doi:10.1007/s12098-017-2544-5
更新日期:2018-11-01 00:00:00
abstract::Hypertransfusion and regular chelation therapy have allowed improved survival in patients with thalassemia major (TM). Despite medical advances, growth failure and hypogonadism remain significant clinical problems in these patients in adolescence. Disproportionate truncal shortening which is common especially among ad...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02760702
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:Nasopharyngeal colonization of Haemophilus influenzae (H. influenzae) in young children may be important in developing countries. METHOD:In this study, we screened school going children for carriage of H. influenzae. A total of 44 H. influenzae isolates out of a collection of 162 were characterized for bioty...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723690
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:This study was carried out to evaluate the adequacy of seroconversion when Hepatitis B vaccine is given along with other vaccines at 0, 6 weeks (along with DPT and OPV) and at 9 months (along with measles). METHODS:725 infants born to apparently healthy mothers were enrolled to receive the hepatitis B vaccin...
journal_title:Indian journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/BF02724073
更新日期:2005-08-01 00:00:00
abstract::Iron overload is a serious and potentially fatal condition that results from multiple blood transfusions required over a long period of time to treat certain types of anemias such as, that caused by beta-thalassemia, sickle cell disease and myelodysplastic syndrome. Deferoxamine, which has been used since four decades...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-010-0030-4
更新日期:2010-02-01 00:00:00
abstract::A 36-hour-old term neonate presented with refractory cardiogenic shock and multi-organ dysfunction. On suspecting coarctation of aorta, intravenous prostaglandin was started but without any benefit. Echocardiography revealed isolated anomalous origin of right pulmonary artery from ascending aorta causing massive aorti...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1416-5
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The authors attempt to determine whether typical clinical and laboratory manifestations of acute rheumatic fever (ARF) are in accordance to what has been traditionally described and how useful the Jones criteria are for diagnosis. METHODS:Data from 81 cases of ARF were retrospectively collected. INCLUSION C...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-007-0001-6
更新日期:2007-02-01 00:00:00
abstract::This article aims to describe the National Family Health Survey (NFHS) being carried out in India with its first round during 1992-93 (NFHS-I) and second round during 1998-99 (NFHS-II), with special reference to information available in relation to children. The survey was on lines of the existing systems of Demograph...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722355
更新日期:2001-11-01 00:00:00
abstract::Computed tomography (CT) is an indispensable tool for imaging of the thorax and there is virtually no alternative without associated radiation burden. The authors demonstrate ultra-low-dose CT of the thorax in three interesting cases. In an 18-y-old girl with rheumatoid arthritis, CT of the thorax identified alveoliti...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-016-2175-2
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To study the prevalence of depression among caregivers of children with cystic fibrosis and its impact on the health and well being of these children. METHODS:This cross-sectional study was conducted in a tertiary care hospital from September 2015 through August 2016. Forty one parents of children receiving ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2695-z
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To measure the economic output/input ratios for the various options of prevention of rheumatic fever/rheumatic heart disease (RF/RHD) and check the viability of primary prevention vis-à-vis secondary and tertiary preventions. METHODS:Cost accounting of the various prevention options was calculated for each v...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-007-0094-y
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:To conduct a community survey to understand the prevalence and type of developmental delay/disability among a representative state wide community sample of children below 3 y. METHODS:A state wide community based cross sectional survey was done with the help of the Integrated Child Development Services (ICDS...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1579-0
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To document the immunization rates, factors associated with incomplete immunization, and missed opportunities for immunizations in children affected by HIV presenting for routine outpatient follow-up. METHODS:A cross-sectional study of immunization status of children affected by HIV presenting for routine ou...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1049-0
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To present evaluation of a quality improvement program for Accredited Social Health Activists (ASHAs). METHODS:This community intervention trial was conducted in Ballabgarh, India during 2012-2014 with two Primary Health Center (PHC) areas being the intervention areas and two PHC areas being non-intervention...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-019-03012-4
更新日期:2019-11-01 00:00:00
abstract::In this review, the clinical features and management of most commonly encountered acyanotic, left-to-right shunt lesions are discussed. Patients with small defects, especially in childhood, are usually asymptomatic while moderate to large defects in infancy may present with symptoms. Hyperdynamic precordium, widely sp...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02724429
更新日期:2005-06-01 00:00:00
abstract::Essential fatty acids cannot be synthesized in the body but they are required for maintenance of optimal health. There are two classes of polyunsaturated fatty acids (PUFAs)--omega-6 and omega-3. The parent omega-6 fatty acid, linoleic acid (LA) is desaturated in the body to form arachidonic acid while parent omega-3 ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract::Cryptosporidium is an intestinal protozoa known to cause diarrhea in animals and more recently has been recognised as a cause of diarrhea in humans. The present study was designed to determine the prevalence of cryptosporidium as a cause of diarrhea in children. Faecal samples of 180 children admitted to the hospital ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02749728
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the antenatal profile of the mother and the immediate neonatal morbidity and mortality till discharge. METHODS:The study was a retrospective analysis of 92 patients of preterm labour who delivered babies weighing RESULTS:A total of 92 mothers in preterm labour at 26 to 34 weeks were admitted and...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02898441
更新日期:2006-08-01 00:00:00