Abstract:
OBJECTIVE:To assess the efficacy of arginine vasopressin (AVP) as a rescue therapy in children with catecholamine refractory vasodilatory shock and its effect on various hemodynamic, clinical, and laboratory variables. METHODS:This prospective hospital based study was conducted from January 2008 through July 2008 at a tertiary pediatric cardiac critical care unit. Twelve post cardiac surgery patients with advanced vasodilatory shock requiring intravenous vasopressin infusion longer than 60 min were included and continuous vasopressin infusion was given. The primary outcome measures were restoration of Mean arterial blood pressure (MAP) after starting AVP infusion and decrease in other concurrent catecholamines requirement. The secondary outcome measures were survival to hospital discharge, adverse effects, and laboratory variables. RESULTS:Vasopressin was infused in the dose range of 0.0005 to 0.003 units/kg/min for a mean duration of 55.6 h. MAP improved from 41.08 ± 6.15 mmHg at baseline to 48.92 ± 10.05 mmHg after 1 h (P < 0.05), to 57.01 ± 8.30 mmHg after 4 h of AVP infusion (P < 0.001), and to 62.33 ± 8.55 mmHg after 12 h (P < 0.001), which further increased to 71.75 ± 9.55 mmHg after 24 h (P < 0.001). Inotrope score and requirement of other concurrent inotropes declined significantly in all patients after starting AVP infusion (P < 0.001). Lactate levels also declined significantly (P < 0.0001). No significant adverse effect due to end organ ischemia was observed. Only one patient expired while on vasopressin infusion due to refractory hypotension. CONCLUSIONS:Concurrent addition of vasopressin at an appropriate stage help improving MAP significantly with decreased dependence on high dose catecholamines without any significant adverse effects.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Agrawal A,Singh VK,Varma A,Sharma Rdoi
10.1007/s12098-011-0557-zsubject
Has Abstractpub_date
2012-04-01 00:00:00pages
488-93issue
4eissn
0019-5456issn
0973-7693journal_volume
79pub_type
杂志文章abstract:OBJECTIVE:To identify pathogens responsible for acute severe lower respiratory tract infection (ALRTI) in under five children by non-invasive methods. METHOD:95 children hospitalized with acute severe lower respiratory tract infection were investigated for identification of viruses, bacteria, chlamydia or mycoplasma b...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722742
更新日期:2003-01-01 00:00:00
abstract::This study was designed to compare two methods of breast milk expression, namely, the manual and the pumping method using a hand-held cylindric pump. The parameters evaluated were (i) the output of breast milk during milk expression sessions of 15 minutes' duration, and, (ii) the subjective preference of the method by...
journal_title:Indian journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/BF02823873
更新日期:1996-01-01 00:00:00
abstract::Distinction between true and pseudo trail in lumbo-sacral region is important since treatment and prognosis are different. Fewer than 40 cases have been reported in literature. The authors report a case of true tail in a neonate, a rare event. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract::Biotin Thiamine responsive Basal Ganglia Disease (BTBGD) is a rare treatable autosomal recessive metabolic disorder caused by mutations in SLC19A3 gene. It usually presents with encephalopathy and dystonia; if not treated, can progress to quadriparesis and death. Two Indian siblings born to a consanguineous marriage p...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2471-5
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To report our experience before and after implementation of pediatric rapid response team (RRT) in pediatric wards of a tertiary care hospital in Pakistan. METHODS:An audit of RRT activity from December 2007 to August 2008 was conducted and reviewed patient diagnoses at the time of call placement, interventi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0032-2
更新日期:2010-03-01 00:00:00
abstract:: ...
journal_title:Indian journal of pediatrics
pub_type: 信件
doi:10.1007/s12098-018-2702-4
更新日期:2019-01-01 00:00:00
abstract::This article reviews the various aspect of the experimental phase preceding the establishment of an umbilical cord blood (UCB) bank within a regular blood bank, a situation totally different from that of de novo establishing a cord blood bank having human and financial resources. An ethically approved two-year study h...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02723589
更新日期:2003-04-01 00:00:00
abstract::Epilepsy is a common childhood neurological morbidity needs careful evaluation, relevant investigations and precise therapy with appropriate antiepileptic drugs for optimal duration. Majority of childhood epilepsy remits with antiepileptic drugs and should be managed in the community. Practising pediatricians must cou...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723743
更新日期:2003-02-01 00:00:00
abstract::The importance of taurine in diet is poorly understood. The present evidence suggests that it is a conditionally essential aminoacid in man wherein deficiency states may result in adverse changes which will be improved with supplementation. It has a role in fat absorption in preterm infants and children with cystic fi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02754955
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVE:To determine the safety and efficacy of off label usage of Recombinant activated factor VII (rFVIIa) in children with severe bleeding in non-hemophiliac children with diverse etiologies like leukemia, post hematopoietic stem cell transplantation, dengue shock syndrome and Glanzmann thrombasthenia. METHOD:Med...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0364-6
更新日期:2011-08-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1579-0
更新日期:2014-12-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02905736
更新日期:1996-07-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2695-z
更新日期:2018-11-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0943-1
更新日期:2013-06-01 00:00:00
abstract::A case of neonatal Bartter syndrome is reported. The baby born pre-term following a pregnancy complicated by polyhydramnios, presented at 7 months of age with failure to thrive, gastroenteritis and facial dysmorphisms. An unusual feature was the absence of the classical biochemical abnormality of hypochloremic alkalos...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723788
更新日期:2002-01-01 00:00:00
abstract::Due to changing characteristics of infective endocarditis in the past two decades, we, retrospectively analysed 28 cases of infective endocarditis in children of age less than 15 years at Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar from December, 1983 to November, 1993. The incidence of disease was o...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02845245
更新日期:1996-03-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02752301
更新日期:1998-03-01 00:00:00
abstract::Advances in immunosuppressive treatment as well as better monitoring and control of acute rejection have brought intestinal transplantation (ITx) into the realm of standard treatment for permanent intestinal failure. The results from the intestinal Transplant International Registry (www.intestinaltransplant.org) indic...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02724317
更新日期:2003-09-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2323-3
更新日期:2017-07-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0653-0
更新日期:2012-09-01 00:00:00
abstract:: ...
journal_title:Indian journal of pediatrics
pub_type: 信件
doi:10.1007/s12098-018-2700-6
更新日期:2018-11-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
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更新日期:2000-02-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726134
更新日期:1997-09-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02737744
更新日期:1997-07-01 00:00:00
abstract::Locked-in syndrome is characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral horizontal gaze palsy and anarthria, with preserved consciousness. It is due to a ventral pontine lesion following a basilar artery occlusion. We report the first Indian case report of locked-in syndrom...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0200-4
更新日期:2009-10-01 00:00:00
abstract::A detailed information on a total of 448 consecutive Nepali births which occurred between January 1, 1985 and December 31, 1994 was collected from the birth registers of the Khasi-Jaintia Presbetyrian Synod Hospital of Shillong, Meghalaya. After the exclusion of still and twin births, and the cases of missing informat...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02760471
更新日期:2000-07-01 00:00:00
abstract::Auditory evoked responses using BERA were studied in 30 newborn babies with plasma bilirubin > or = 15 mgm/dl and repeated after treatment of neonatal jaundice with bilirubin levels of < or = 10 mgm/dl. A few jaundiced babies (16.5%) showed absent BERA response at the initial/subsequent examination. After treatment, 3...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751203
更新日期:1993-05-01 00:00:00
abstract::A pair of female thoraco-omphalopagus twins, with two pairs of lungs, common diaphragm and separate pleural cavities was separated at the age of 5(1/2) months after a parasitic relationship had developed between them. Before separation both the babies developed recurrent respiratory tract infection and frequent diarrh...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02730669
更新日期:2004-08-01 00:00:00
abstract::To study pulmonary function tests (PFT) in multiple transfusion recipient thalassemics, PFTs were done for 30 thalassemics and 20 matched controls. Confirmed cases of thalassemia on regular transfusion therapy were the subject of study. Apart from history and physical examination of the thalassemics, serum ferritin es...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723198
更新日期:2001-03-01 00:00:00