Abstract:
OBJECTIVE:To determine pulmonary function abnormalities in children with Sickle Cell Disease (SCD) from Western India. METHODS:In this cross sectional study conducted at Surat, Gujarat, India; equal number of age and gender matched children i.e., 99 in the age group of 6-18 y was recruited in case (children with SCD) and control (non-SCD healthy children) groups respectively. Weight, height, body mass index (BMI) and hemoglobin (Hb) were assessed as baseline characteristics and spirometry was performed to assess the pulmonary function. RESULTS:The two groups of children were comparable in the baseline characteristics such as weight, height and BMI, however mean hemoglobin was significantly low in SCD as compared to healthy controls [9.1 ± 1.52 vs. 11.4 ± 1.04 (p=0.001)]. Mean (% predicted) Forced expiratory volume in 1 s (FEV1) (86.79 ± 11.6 vs. 94.3 ± 16.1) and FVC (84.4 ± 11.5 vs. 91.75 ± 15.2) values were significantly low (p < 0.001) in cases. CONCLUSIONS:The present study revealed that the difference of pulmonary function tests between sickle cell patients and normal age matched controls were statistically significant but this difference was not clinically significant.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Purohit R,Rao SS,Goyal JP,Shah VB,Charan Jdoi
10.1007/s12098-016-2065-7subject
Has Abstractpub_date
2016-08-01 00:00:00pages
783-6issue
8eissn
0019-5456issn
0973-7693pii
10.1007/s12098-016-2065-7journal_volume
83pub_type
杂志文章abstract:OBJECTIVES:To identify risk factors and outcomes associated with early failure of nasal continuous positive airway pressure (CPAP) in premature infants with respiratory distress (RD). METHODS:This is a retrospective observational study of all the preterm infants with RD primarily supported on nasal CPAP and included i...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03399-5
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:To assess performance of WHO 2006 standards on anthropometric measurements of children referred for growth related disorders to a speciality pediatric clinic in Pune, India, from June 2006 through June 2010. METHODS:Data presented in this study were collected retrospectively from case records of all children...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0687-y
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To study the clinical profile, immediate outcome and possible risk factors of SE in pediatric age group admitted to pediatric intensive care unit (PICU) in a tertiary care center. METHODS:A retrospective study of case records of 451 neuroemergency patients admitted in PICU in a tertiary care center between J...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02760691
更新日期:2005-02-01 00:00:00
abstract::A comparison of mortality and morbidity pattern of hospital admissions of children under 14 years during 1966-68 and 1977-81 has been made. Annual admission rate has increased from 1515 to 2515, which is in proportion to the population increase of 3 lacs from 1966 to 1981. Recently more than 70% were discharged within...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726772
更新日期:1990-07-01 00:00:00
abstract::Interpersonal communication between pediatricians and mothers is both complex and interdependent. The mother is dependent on the pediatrician for her child's wellbeing and care along expertise-related dimensions for which she cannot provide. The pediatrician is dependent on the mother's ability to provide accurate inf...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-012-0934-2
更新日期:2013-12-01 00:00:00
abstract::The Polymerase Chain Reaction (PCR) is a revolutionary new means of amplifying, i.e., replicating, selected DNA sequences in vitro. This procedure is highly sensitive and rapid, requiring few hours for detection of amplified target DNA whereas it often takes several weeks for the identification of many fastidious orga...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02737744
更新日期:1997-07-01 00:00:00
abstract::Japanese encephalitis (JE)-epidemics have been reported in many parts of the country. The incidence has been reported to be high among pediatric group with high mortality. The incidence of JE in recent times is showing an increasing trend. It appears that JE may become one of the major public health problems in India,...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02724120
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:To compare the clinical profile and short-term outcome of children with axonal and demyelinating subtypes of childhood Guillain Barré syndrome (GBS). METHODS:This is a prospective observational study conducted in a tertiary care teaching hospital in North India. Consecutive children with Guillain Barré synd...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2835-5
更新日期:2019-04-01 00:00:00
abstract::CMV is a ubiquitous virus. In India, there is high seroendemicity with almost 99% adults showing IgG antibodies. Infection or re-activation becomes important in immunocompromised host (Transplant recipients, Cancer therapy patients and patients with HIV/AIDS). Neonates form a distinctive high risk population for conge...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0255-2
更新日期:2010-01-01 00:00:00
abstract::Immunoglobulin isotypes (IgG, IgA, IgM, IgD, IgE) in serum were investigated in 64 Libyan children with mild to moderately severe asthma (age: 1-12 years; sex: 39 males, 25 females) (Group A) and in 57 healthy Libyan children (age: 1-12 years; sex: 30 males, 27 females (Group B). The patients were classified according...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02845519
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:To understand how decisions are made in Intensive Care Unit (ICU) settings where critically-ill children require life-support decisions and what are the perceptions of health professionals and parents. METHODS:In this qualitative study, in-depth, semi-structured, face to face interviews with 8 doctors, 9 nu...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1431-6
更新日期:2014-12-01 00:00:00
abstract::Nutrition plays a vital role in maintaining and enhancing the health of an individual. As mortality within intensive care units declines because of increased expertise and better equipment, attention is being focused on better methods of feeding the critically ill child. Feeding the child is one aspect that has been r...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02721839
更新日期:2001-04-01 00:00:00
abstract::Tumor lysis syndrome (TLS) refers to the constellation of deranged metabolic state, characterized by hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, and/or azotemia, secondary to rapid breakdown of tumor cells. It is a life threatening emergency that typically follows administration of chemotherapy or ma...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0824-7
更新日期:2013-01-01 00:00:00
abstract::We studied 289 newborn infants from birth till one year of age. Low birth weight babies (less than 2.5 kg) were 52.9%. Boys suffered 9.7 episodes of sickness, and girls 8.6 episodes of sickness. The mean episodes of various sicknesses, and their impact on weight gain, feeding pattern and growth pattern are discussed. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726615
更新日期:1989-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the efficacy and safety of nitazoxanide in intestinal parasitic infections in children. METHODS:Four databases, PubMed, EMBASE, Web of Science and Cochrane Library, have been systematically searched from the inception of each database up to March 1st, 2019. The enrolled studies were limited to r...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,meta分析
doi:10.1007/s12098-019-03098-w
更新日期:2020-01-01 00:00:00
abstract::Advances in diagnosis and treatment along with improved supportive care have contributed to the current survival rates for pediatric malignancies. Recent concept of a truly "cured child" in pediatric oncology envisages not only a biological cure of the disease but a child on par with peers in growth and development ph...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723807
更新日期:2003-10-01 00:00:00
abstract::We studied the auditory brainstem responses of 50 high risk neonates from NICU and compared with those of 25 normal neonates in order to determine the percentage of significant auditory impairment in NICU and correlated it to various risk factors. Infants with the risk factors of low birth weight, hyperbilirubinemia, ...
journal_title:Indian journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/BF02725499
更新日期:1997-11-01 00:00:00
abstract::Surgical treatment for congenital heart disease has become available over the last five decades. Palliative procedures have been designed to improve physiologic abnormalities, for example systemic artery (or venous) to pulmonary artery shunts of various types to increase the pulmonary blood flow, pulmonary artery cons...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02820180
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:To review contemporary guidelines and therapies for pediatric cardiac arrest and discuss potential novel therapies. METHODS:Key articles and guidelines in the field were reviewed along with recent publications in the fields of neurointensive care and neuroscience germane to cerebral resuscitation. RESULTS:A...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-008-0117-3
更新日期:2008-06-01 00:00:00
abstract::Developmental disabilities (DD) are defined as a diverse group of severe chronic conditions due to mental and/or physical impairments. Individuals with developmental disabilities have difficulty with major life activities including language, mobility, and learning. Developmental disabilities can begin anytime during d...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02731671
更新日期:2005-11-01 00:00:00
abstract::Malignant tumours of the chest wall are rare in the pediatric age group. Askin tumour, a primitive neuroectodermal tumour with aggressive nature, is extremely rare. Clinico-pathological features make it quite distinct from Ewing's sarcoma. Aggressive nature of the tumour results in short clinical presentation of the p...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726235
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of an MRI-specific play therapy intervention on the need for sedation in young children. METHODS:All children in the age group of 4-10 y, who were advised an MRI scan over a period of one year were randomized. Exclusion criteria included children with neurodevelopmental disorder...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12098-015-1917-x
更新日期:2016-03-01 00:00:00
abstract::Neonates are among those patients generating the highest hospital costs in recent years. There are no published data on the costs of neonatal intensive care in our country. The aim of our study was to analyse the cost of neonatal intensive care in a tertiary care unit. The average hospital charges per day were higher ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02752301
更新日期:1998-03-01 00:00:00
abstract::Nutritional support to patients in neonatal and pediatric intensive care units is critical not only to minimize negative nitrogen balance but also to promote growth and development. Continuous technological and logistical advances in the Western countries have improved the efficacy and reduced the complications of par...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract::Two cases of Wilson's disease with unusual features are reported. In one case neurological abnormality was the presenting feature without any clinical involvement of the liver. In the other case, neurologic manifestations were associated with rickets and cholelithiasis, a result of chronic hemolytic state. Apart from ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02830841
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:To compare parent reported sleep behaviors of children with Autism Spectrum Disorders (ASD) and normal healthy controls and to examine the association of sleep disturbances with daytime behavioral difficulties in children with ASD. METHODS:Sixty ASD children (85% boys) (Mean age=6.1 y, SD=2.4) were recruite...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2731-z
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The present study aimed to estimate the prevalence of acute diarrhea and its correlates in remote rural villages of south Pakistan. METHODS:The authors selected 1878 children less than 3 years of age through stratified random sampling from 64 villages having the number of children enrolled proportionate to t...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02725583
更新日期:2003-03-01 00:00:00
abstract::Nosocomial infections in Pediatric Intensive Care Units (PICUs) caused by multidrug-resistant bacterial organisms are increasing. This review attempts to report on significant findings in the current literature related to nosocomial infections in PICU settings with an international perspective. The types of nosocomial...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-010-0253-4
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of early onset Group B Streptococcal (GBS) infection in infants born over a two year period and to determine the outcome of sepsis evaluation in infants born to mothers with GBS colonization. METHODS:The charts of infants born to mothers with GBS colonization were reviewed for deta...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02759920
更新日期:2006-07-01 00:00:00
abstract::Adrenal hemorrhage has many etiologies including bleeding diathesis. A 10-day-old female baby was admitted to our clinic with the complaint of abdominal distention. Hemorrhage was determined on the right adrenal gland with abdominal ultrasonography and computerized tomography. Laboratory investigations showed PT 44 se...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723786
更新日期:2002-01-01 00:00:00