GCD quantitation of opiates as propionyl derivatives in blood.

abstract：:There has been a recent and significant increase in the use and availability of hemp seed oil products. These products are being marketed as a healthy source of essential omega fatty acids when taken orally. Although the health aspects of these oils is open to debate, the probability that oils derived from the hemp se...

journal_title：Journal of analytical toxicology

authors： Bosy TZ,Cole KA

更新日期：2000-10-01 00:00:00

abstract：:A high-performance liquid chromatographic method has been developed for the simultaneous analysis of eight frequently used benzodiazepines and some of their metabolites in postmortem samples. The method includes a liquid-liquid extraction with n-hexane-ethyl acetate (70:30, v/v), gradient elution of a C8 reversed-phas...

journal_title：Journal of analytical toxicology

authors： Lambert WE,Meyer E,Xue-Ping Y,De Leenheer AP

更新日期：1995-01-01 00:00:00

abstract：:In Europe, the compound 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy, Adam), in addition to cannabis, is the most abused illicit drug at all-night "techno" parties. Methods for the determination of MDMA and its metabolites, 4-hydroxy-3-methoxymethamphetamine (HMMA), 3,4-dihydroxy-methamphetamine (HHMA), 3,4-methyl...

journal_title：Journal of analytical toxicology

authors： Helmlin HJ,Bracher K,Bourquin D,Vonlanthen D,Brenneisen R

更新日期：1996-10-01 00:00:00

abstract：:Bleach, nitrite, chromate, and hydrogen peroxide-peroxidase are effective urine adulterants used by the illicit drug users to conceal marijuana-positive results. Methods for detecting nitrite and chromate are available. Effects of other oxidizing agents that could possibly be used as adulterants and are difficult to d...

journal_title：Journal of analytical toxicology

authors： Paul BD,Jacobs A

更新日期：2002-10-01 00:00:00

abstract：:A fast and efficient multiresidue extraction-purification procedure was developed for low levels (ppb range) of phenanthrene and hydroxyphenanthrene in biological matrices, in order to quantify phenanthrene and metabolites in blood, milk, urine, and biological tissues of lactating goats. Detection and identification o...

journal_title：Journal of analytical toxicology

authors： Grova N,Monteau F,Le Bizec B,Feidt C,Andre F,Rychen G

更新日期：2005-04-01 00:00:00

abstract：:A rapid, simple, highly sensitive procedure for the simultaneous analysis of bromazepam, alprazolam, clonazepam, lorazepam, oxazepam, diazepam, midazolam, flurazepam, flunitrazepam, nordiazepam, triazolam, temazepam, nitrazepam, and chlordiazepoxide in oral fluid is described, using liquid chromatography coupled to a ...

journal_title：Journal of analytical toxicology

authors： Moore C,Coulter C,Crompton K,Zumwalt M

更新日期：2007-11-01 00:00:00

abstract：:The Substance Abuse and Mental Health Services Administration (SAMHSA) is currently evaluating hydrocodone (HC) for inclusion in the Mandatory Guidelines for Federal Workplace Drug Testing Programs. This study evaluated the time course of HC, norhydrocodone (NHC), dihydrocodeine (DHC) and hydromorphone (HM) in paired ...

journal_title：Journal of analytical toxicology

authors： Cone EJ,DePriest AZ,Heltsley R,Black DL,Mitchell JM,LoDico C,Flegel R

更新日期：2015-09-01 00:00:00

abstract：:A 5-mg dose of cocaine free base applied to the volar forearm skin surface of a volunteer resulted in a maximal urinary benzoylecgonine concentration of 55 ng/mL at 48 h, using discrete urine specimens. A total of 58 micrograms of benzoylecgonine, representing 1.2% of the dose, was excreted in the 96-h urine. An ident...

journal_title：Journal of analytical toxicology

authors： Baselt RC,Chang JY,Yoshikawa DM

更新日期：1990-11-01 00:00:00

abstract：:The purpose of this study was to develop and validate a gas chromatography-mass spectrometry method to detect drugs of abuse in a single sample of tooth. Pulverized samples of dental materials were subjected to acid hydrolysis to detect opiates, cocaine and their metabolites. The residual dental materials from these a...

journal_title：Journal of analytical toxicology

authors： Ottaviani G,Cameriere R,Cippitelli M,Froldi R,Tassoni G,Zampi M,Cingolani M

更新日期：2017-01-01 00:00:00

abstract：:Due to the lack of certified reference material, a reliable quantification in complex postmortem matrices can only be performed either by the addition of isotope-labelled standards or by the standard addition method. Although standard addition is a basic quantification procedure, its practical implementation is challe...

journal_title：Journal of analytical toxicology

authors： Reiter B,Stimpfl T

更新日期：2015-11-01 00:00:00

abstract：:A study of the urinary concentration of fentanyl (F) and its major metabolite norfentanyl (NF) in chronic pain patients treated with the Duragesic continuous release transdermal patches is presented. These patches are available in 10, 20, 30, and 40 cm(2) sizes releasing 25, 50, 75, and 100 microg/h F, respectively. F...

journal_title：Journal of analytical toxicology

authors： Poklis A,Backer R

更新日期：2004-09-01 00:00:00

abstract：:The guidelines for screening of urinary cannabinoids require that all specimens testing positive should be confirmed by gas chromatography-mass spectrometry at a confirmatory test cutoff value of 15 ng/mL of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCCOOH). To assess the impact of lowering the confirmatory test cuto...

journal_title：Journal of analytical toxicology

authors： Lecompte Y,Perrin M,Salle S,Roussel O

更新日期：2012-10-01 00:00:00

abstract：:A clinical study was designed to determine if there was a predictable relationship between saliva and plasma codeine concentrations. Drug-free volunteers (n = 17) were administered a 30-mg dose of liquid codeine phosphate. Plasma and saliva specimens were collected at various times for 24 h after administration. Plasm...

journal_title：Journal of analytical toxicology

authors： O'Neal CL,Crouch DJ,Rollins DE,Fatah A,Cheever ML

更新日期：1999-10-01 00:00:00

abstract：:A method is presented for the positive identification of quinine and quinidine. The method requires extraction of the compounds from an alkaline solution into an organic solvent and concentration of the sample by evaporation of the solvent. The sample is chromatographed without derivatization and may be detected by th...

journal_title：Journal of analytical toxicology

authors： Furner RL,Brown GB,Scott JW

更新日期：1981-11-01 00:00:00

abstract：:We developed a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS-MS) method to measure metabolites of atrazine, phenylurea, and sulfonylurea herbicides in human urine. The metabolites measured in the method include atrazine mercapturate, desethyl atrazine, and desisopropyl atrazine as markers of...

journal_title：Journal of analytical toxicology

authors： Nguyen JV,Olsson AO,Bravo R,Needham LL,Barr DB

更新日期：2007-05-01 00:00:00

abstract：:Synthetic cannabinoids emerged on the designer drug market in recent years due to their ability to produce cannabis-like effects without the risk of detection by traditional drug testing techniques such as immunoassay and gas chromatography-mass spectrometry. As government agencies work to schedule existing synthetic ...

journal_title：Journal of analytical toxicology

authors： Knittel JL,Holler JM,Chmiel JD,Vorce SP,Magluilo J Jr,Levine B,Ramos G,Bosy TZ

更新日期：2016-04-01 00:00:00

abstract：:The metabolism of N-benzylpiperazine (BZP), a recently scheduled designer drug, in the rat has been studied by analyzing its urinary metabolites. p-Hydroxy-BZP (p-OH-BZP) was unequivocally identified as the main metabolite along with a minor metabolite m-hydroxy-BZP (m-OH-BZP), using gas chromatography-mass spectromet...

journal_title：Journal of analytical toxicology

authors： Tsutsumi H,Katagi M,Miki A,Shima N,Kamata T,Nakajima K,Inoue H,Kishi T,Tsuchihashi H

更新日期：2006-01-01 00:00:00

abstract：:A sensitive and specific method was developed for the quantitative analysis of l-alpha-acetylmethadol (LAAM), l-alpha-acetyl-N-normethadol (norLAAM), and l-alpha-acetyl-N,N-dinormethadol (dinorLAAM) in hair. In the development of this method, it was determined that sample pretreatment methods performed by the laborato...

journal_title：Journal of analytical toxicology

authors： Wilkins DG,Valdez AS,Krueger GG,Rollins DE

更新日期：1997-10-01 00:00:00

abstract：:Hop-derived iso-α-acid (IAA) ingredient congeners are specific to beer. Concentrations of IAAs were determined in blood of five volunteers over 6 h following the consumption of small volumes of beer containing relatively high (Pale Ale beer) or low (wheat beer) concentrations of IAAs. IAAs were quickly absorbed with p...

journal_title：Journal of analytical toxicology

authors： Rodda LN,Gerostamoulos D,Drummer OH

更新日期：2014-07-01 00:00:00

abstract：:British anti-Lewisite (BAL) (2,3-dimercapto-1-propanol) is a potential therapeutic compound when used against the effects of cutaneous sulfur mustard, and a method for its determination in plasma has been developed. BAL and the internal standard (IS) ethane dithiol were isolated from plasma samples through solid-phase...

journal_title：Journal of analytical toxicology

authors： Byers CE,Holloway ER,Korte WD,Smith JR,Clarkson ED,Platoff GE,Capacio BR

更新日期：2004-07-01 00:00:00

abstract：:This manuscript reviews data available in the scientific literature relative to drug testing for the five mandated drug classes and circumstances other than abuse of the drug itself that could result in a positive test. For marijuana, passive inhalation, unknowing oral ingestion, and the use of Marinol are discussed. ...

journal_title：Journal of analytical toxicology

authors： elSohly MA,Jones AB

更新日期：1995-10-01 00:00:00

abstract：:In previous experimental studies on heroin metabolites excretion in urine, the first sample was often collected a few hours after intake. In forensic cases, it is sometimes questioned if a positive urine result is expected e.g., 30 min after intake. The aim of this study was to investigate urinary excretion of heroin ...

journal_title：Journal of analytical toxicology

authors： Høiseth G,Gottås A,Berg T,Arnestad M,Halvorsen PS,Bachs LC

更新日期：2017-06-01 00:00:00

abstract：:A simple, rapid, and reliable gas-liquid chromatographic (GLC) confirmation procedure was developed for urine samples found positive by the EMIT-dau benzodiazepine metabolite assay. The procedure involves acid hydrolysis, organic extraction, and identification using GLC-nitrogen-phosphorus detection (NPD). The method ...

journal_title：Journal of analytical toxicology

authors： Verebey K,Jukofsky D,Mulé SJ

更新日期：1982-11-01 00:00:00

abstract：:New psychoactive substances (NPS) are a major public health problem, primarily due to the increased number of acute poisoning cases. Detection of these substances is a challenge. The aim of this research was to develop and validate a sensitive screening method for 104 drugs of abuse, including synthetic cannabinoids, ...

journal_title：Journal of analytical toxicology

authors： da Cunha KF,Oliveira KD,Huestis MA,Costa JL

更新日期：2020-10-12 00:00:00

abstract：:The objective of this project was to validate a new high-throughput homogeneous enzyme immunoassay (HEIA) for the rapid detection of carisoprodol in human urine. Carisoprodol (Soma(®)) and meprobamate are widely prescribed as musculoskeletal pain relief drugs and are listed as one of the 10 most frequently identified ...

journal_title：Journal of analytical toxicology

authors： Wang G,Huynh K,Barhate R,Rodrigues W,Moore C,Coulter C,Vincent M,Soares J

更新日期：2011-03-01 00:00:00

abstract：:This work was aimed at developing and validating a hydrophilic interaction chromatography (HILIC)-electrospray ionization (ESI)-ion trap-tandem mass spectrometric method for identification and quantification of ethyl glucuronide (ETG) and ethyl sulfate (ETS) as ethanol biomarkers and at employing this method for analy...

journal_title：Journal of analytical toxicology

authors： Al-Asmari AI,Anderson RA,Appelblad P

更新日期：2010-06-01 00:00:00

abstract：:A suicide caused by oral ingestion of colchicine is reported. Postmortem examination revealed circulating Pelger-Huet polymorphonuclear leukocytes and numerous mitotic and chromatin bodies in tissues with rapid cell turnover. Colchicine was identified by gas chromatography/mass spectrometry (GC/MS) of an organic extra...

journal_title：Journal of analytical toxicology

authors： Clevenger CV,August TF,Shaw LM

更新日期：1991-05-01 00:00:00

abstract：:A method for the determination of the antidepressant drug trazodone is presented. 8-Hydroxyloxapine is used as the internal standard. A simple solid-phase extraction procedure utilizing disposable reversed-phase C18 columns is described. Samples are analyzed by gas chromatography with nitrogen-selective detection usin...

journal_title：Journal of analytical toxicology

authors： Rifai N,Levtzow CB,Howlett CM,Phillips JC,Parker NC,Cross RE

更新日期：1988-05-01 00:00:00

abstract：:External contamination of hair or nails by inorganic arsenic compounds cannot effectively be removed with H2O or dilute HCl. The use of a modified Gutzeit apparatus allowed to establish or rule out external contamination. It was found that contaminated samples will generate large amounts of arsine gas when treated wit...

journal_title：Journal of analytical toxicology

authors： Pirl JN,Townsend GF,Valaitis AK,Grohlich D,Spikes JJ

更新日期：1983-09-01 00:00:00

abstract：:A rapid capillary gas-liquid chromatographic method for the determination of barbiturates in plasma at concentrations of clinical importance is presented. This method employs a rapid and simple extraction procedure and direct flame ionization detection with no derivatization. ...

journal_title：Journal of analytical toxicology

authors： Wallace JE,Hall LR,Harris SC

更新日期：1983-07-01 00:00:00