Death by arsenic: a comparative evaluation of exhumed body tissues in the presence of external contamination.

abstract：:A colchicine blood concentration 250 microgram/L was determined in a 39-year-old white female 2 hours following the ingestion of an oral overdose of the drug. At death, 40 hours following ingestion, no drug was detected. Colchicine was extracted from buffered blood using dichloromethane. The evaporated extract was red...

journal_title：Journal of analytical toxicology

authors： Caplan YH,Orloff KG,Thompson BC

更新日期：1980-05-01 00:00:00

abstract：:As an approved medicinal product and reportedly an abused substance that have been associated with death and "considered to be a factor...of impaired driving, sexual assault, and other violent crimes", triazolam is controlled at the same level (Level III) as flunitrazepam in Taiwan. Alleged misuses of this substance h...

journal_title：Journal of analytical toxicology

authors： Lin DL,Huang TY,Liu HC,Yin RM

更新日期：2005-03-01 00:00:00

abstract：:Toxicological analyses of medicines and chemicals in formaldehyde-treated specimens are a component of forensic toxicology. This review involves two parts: (i) reactions of formaldehyde with substances in tissues fixed with formalin (aqueous formaldehyde solution) and (ii) the stability of substances in formalin-treat...

journal_title：Journal of analytical toxicology

authors： Takayasu T

更新日期：2013-11-01 00:00:00

abstract：:Six cases involving the antidepressant mirtazapine were analyzed in detail at the San Diego County Medical Examiner's Office from 2004 to 2005. Mirtazapine was initially detected and confirmed in each of these cases by a liquid-liquid gas chromatography (GC)-MS basic drug screen. Following another liquid-liquid basic ...

journal_title：Journal of analytical toxicology

authors： Kirkton C,McIntyre IM

更新日期：2006-11-01 00:00:00

abstract：:The aim of this study is to investigate the distribution of methamphetamine (MA) and its metabolite amphetamine (AP) in rat models of acute and subacute MA-ethanol combination abuse. Rats were fed with 20% ethanol for 4 weeks (chronic active-drinking group), and MA was injected intraperitoneally into chronically drink...

journal_title：Journal of analytical toxicology

authors： Liang M,Liu Y,Zheng N,Ananda S,Liu L

更新日期：2012-01-01 00:00:00

abstract：:Although the legitimate clinical use of amphetamine and amphetamine congeners is declining, the illicit use of these drugs remains high. There is a need for a rapid and conclusive method for detecting these compounds in routine urine drug testing, drug screening in drug rehabilitation centers, and as an aid in the dia...

journal_title：Journal of analytical toxicology

authors： Przekop MA,Manno JE,Kunsman GW,Cockerham KR,Manno BR

更新日期：1991-11-01 00:00:00

abstract：:The aim of the present study was to develop and validate a method for the detection and quantitation of drugs of abuse in oral fluids. Fortified oral fluid samples (made in-house) and samples from donors collected with Quantasil oral fluid collection kits from Immunalysis were screened on an Olympus 5400 using reagent...

journal_title：Journal of analytical toxicology

authors： Kala SV,Harris SE,Freijo TD,Gerlich S

更新日期：2008-10-01 00:00:00

abstract：:The effects of decomposition microclimate on the distribution of dextromethorphan (DXM) and dextrorphan (DXT) in skeletonized remains of rats acutely exposed to DXM were examined. Animals (n = 10) received DXM (75 mg/kg, i.p.), were euthanized 30 min post-dose and immediately allowed to decompose at either Site A (sha...

journal_title：Journal of analytical toxicology

authors： Unger KA,Watterson JH

更新日期：2016-10-01 00:00:00

abstract：:The analysis of biological specimens collected at autopsy for the presence of exogenous insulin(s) is of special interest in select death investigations as they may be suspected in the cause of a death. Technical challenges include the limited stability of insulin, and the forensic requirement of differentiating endog...

journal_title：Journal of analytical toxicology

authors： Legg KM,Labay LM,Aiken SS,Logan BK

更新日期：2019-08-23 00:00:00

abstract：:In mothers who had no prenatal care and in their newborns, the presence of cocaine and benzoylecgonine (BE) was determined in urine, hair, and meconium. Samples of urine and hair were obtained from pregnant women who entered the hospital for delivery. Cocaine usage was assessed by a urinary enzyme-multiplied immunoass...

journal_title：Journal of analytical toxicology

authors： DiGregorio GJ,Ferko AP,Barbieri EJ,Ruch EK,Chawla H,Keohane D,Rosenstock R,Aldano A

更新日期：1994-09-01 00:00:00

abstract：:Uncertainty is an inherent property of all measurements. The magnitude of this uncertainty will determine the number of meaningful digits that should be reported in a measurement result. Several statistical arguments are considered providing evidence that three digit truncated results are more appropriate than two sin...

journal_title：Journal of analytical toxicology

authors： Gullberg RG

更新日期：2015-06-01 00:00:00

abstract：:An original high-performance liquid chromatographic-mass spectrometric (HPLC-MS) procedure was developed for the determination of cyanide (CN) in whole blood. After the addition of K13C15N as internal standard, blood was placed in a microdiffusion device, the inner well of which was filled with a mixture of taurine (5...

journal_title：Journal of analytical toxicology

authors： Tracqui A,Raul JS,Géraut A,Berthelon L,Ludes B

更新日期：2002-04-01 00:00:00

abstract：:Ethiofencarb is one of the carbamate compounds, which are, in general, less toxic than organophosphorus insecticides. This is due to their reversible acetylcholinesterase inhibition and relative inability to cross the blood-brain barrier. Generally, ethiofencarb is regarded to be of low toxicity (LD(50) > 200 mg/kg); ...

journal_title：Journal of analytical toxicology

authors： Al-Samarraie MS,Karinen R,Rognum T,Hasvold I,Opdal Stokke M,Christophersen AS

更新日期：2009-09-01 00:00:00

abstract：:N,N-Diethyl-m-toluamide (DEET) is an effective component of several insect repellent products. A 19-year-old woman was admitted to the emergency department following ingestion of 15-25 mL 95% diethyltoluamide (Muscol). Serum and urine toxicology screening tests were negative except for detection of DEET. DEET was qual...

journal_title：Journal of analytical toxicology

authors： Fraser AD,MacNeil A,Theriault M,Morzycki W

更新日期：1995-05-01 00:00:00

abstract：:A sensitive and reproducible gas chromatographic procedure for the quantitative determination of urinary o-cresol is described. The first step involves acid hydrolysis (2N HCl, 100 degrees C, 10 min), which yields unconjugated o-cresol. After extraction (methylene chloride, pH 2), the organic layer is concentrated by ...

journal_title：Journal of analytical toxicology

authors： Truchon G,Tardif R,Brodeur J

更新日期：1996-09-01 00:00:00

abstract：:Since the introduction in 1990, the solid-phase microextraction (SPME) technology has brought significant progress in many fields of forensic sciences due to the versatility of this fast and solventless alternative to conventional extraction techniques. A systematic review about SPME applications in forensic context f...

journal_title：Journal of analytical toxicology

authors： De Giovanni N,Marchetti D

更新日期：2020-04-30 00:00:00

abstract：:A new point-of-care colloidal metal immunoassay urine drugs-of-abuse testing device, the BIOSITE TRIAGE Plus Propoxyphene (TPP), was evaluated for the rapid detection of dextropropoxyphene (PPY) and/or its primary metabolite, norpropoxyphene (NP), in urine at a total PPY/NP concentration of 300 ng/mL or greater. This ...

journal_title：Journal of analytical toxicology

authors： Poklis A,Poklis JL,Tarnai LD,Backer RC

更新日期：2004-09-01 00:00:00

abstract：:Methoxphenidine (MXP, 2-MeO-diphenidine) is a dissociative anaesthetic drug of the diarylethylamine type, recently introduced for recreational purposes through the online-based sale of new psychoactive substances (NPS). The concentration of MXP in hair has never been reported, either in cases of chemsex use or in fata...

journal_title：Journal of analytical toxicology

authors： Goncalves R,Castaing N,Titier K,Dumestre-Toulet V

更新日期：2021-02-01 00:00:00

abstract：:Methyl methacrylate polymer (PolyMMA) is widely used as the composite resin for the dental plate. During the fabrication process of PolyMMA for the polymerization reaction, benzoylperoxide (BPO) and N,N-dimethyl p-toluidine (DMPT) are added as the initiator and the stimulator, respectively. Because these compounds exh...

journal_title：Journal of analytical toxicology

authors： Shintani H,Tsuchiya T,Hata Y,Nakamura A

更新日期：1993-03-01 00:00:00

abstract：:The popularity of designer drugs has increased over the past few years as users seek new, cheap and sometimes "legal" ways to get high. This case report focuses on a case that happened in the City of Henderson, Nevada, which involved the designer drug methoxetamine. Methoxetamine is a psychoactive compound that is str...

journal_title：Journal of analytical toxicology

authors： Fassette T,Martinez A

更新日期：2016-10-01 00:00:00

abstract：:This study evaluated the validity of measuring fentanyl concentrations in equine plasma using radioimmunoassay (RIA) by comparing it to the established technique of liquid chromatography-mass spectrometry (LC-MS). Equine plasma samples were analyzed using a solid-phase Coat-A-Count fentanyl RIA and a validated LC-MS m...

journal_title：Journal of analytical toxicology

authors： Thomasy SM,Mama KR,Stanley SD

更新日期：2008-11-01 00:00:00

abstract：:A method is presented for the analysis of trace amounts of dinitroaniline herbicides in tissue and excreta. The method employs extraction of the tissue or excreta with organic solvent, clean up by liquid/liquid partitioning or silica gel chromatography, and ultimate analysis by gas chromatography using electron captur...

journal_title：Journal of analytical toxicology

authors： Edgerton TR,Scott W,Linder RE

更新日期：1985-01-01 00:00:00

abstract：:3,4-Methylenedioxypyrovalerone (MDPV) is a psychoactive, synthetic analog of the central nervous system stimulant cathinone. Its recent popularity as a recreational drug in the United States has led to numerous reports to poison control centers across the country. As with other synthetic cathinones, the recreational u...

journal_title：Journal of analytical toxicology

authors： Wyman JF,Lavins ES,Engelhart D,Armstrong EJ,Snell KD,Boggs PD,Taylor SM,Norris RN,Miller FP

更新日期：2013-04-01 00:00:00

abstract：:A high-performance liquid chromatographic system based on gradient elution of an alumina packing material coated with polybutadiene is presented. The chromatographic eluent is a mixture of methanol and water, both containing 0.0125M NaOH. The effluent is monitored by photodiode array detection. The system allows detec...

journal_title：Journal of analytical toxicology

authors： Lambert WE,Meyer E,De Leenheer AP

更新日期：1995-03-01 00:00:00

abstract：:Metabolism experiments were conducted with rats dosed with nine azo dyes based on dimethyl-, dimethoxy-, or dichlorobenzidine to determine whether the free amine congeners, their monoacetyl or diacetyl metabolites, or alkaline hydrolyzable conjugates were excreted in the urine. After preliminary tests of the dyes, 2-m...

journal_title：Journal of analytical toxicology

authors： Bowman MC,Nony CR,Billedeau SM,Martin JL,Thompson HC Jr,Lowry LK

更新日期：1983-01-01 00:00:00

abstract：:A rapid, simple, highly sensitive procedure for the simultaneous analysis of bromazepam, alprazolam, clonazepam, lorazepam, oxazepam, diazepam, midazolam, flurazepam, flunitrazepam, nordiazepam, triazolam, temazepam, nitrazepam, and chlordiazepoxide in oral fluid is described, using liquid chromatography coupled to a ...

journal_title：Journal of analytical toxicology

authors： Moore C,Coulter C,Crompton K,Zumwalt M

更新日期：2007-11-01 00:00:00

abstract：:Confirmation of drugs of abuse by gas chromatography-mass spectrometry (GC-MS) is the most time-consuming process used by drug-testing laboratories. Cost effectiveness and competitive turnaround times for testing results demand fast, efficient, and reliable extraction methods. We applied the Cerex Polycrom-THC solid-p...

journal_title：Journal of analytical toxicology

authors： Crockett DK,Nelson G,Dimson P,Urry FM

更新日期：2000-05-01 00:00:00

abstract：:Because mycotoxins occur worldwide in grain and grain products, evaluating their effects on the health of the population has become important. The development of a high performance liquid chromatographic (HPLC) procedure was investigated for the analysis of aflatoxin B1, citrinin, and ochratoxin A, from hydrolyzed hum...

journal_title：Journal of analytical toxicology

authors： Orti DL,Hill RH Jr,Liddle JA,Needham LL,Vickers L

更新日期：1986-03-01 00:00:00

abstract：:Oral fluid (OF) is increasingly used for clinical, forensic and workplace drug testing as an alternative to urine. Uncertainties surrounding OF collection device performance, drug stability and testing reproducibility may be partially responsible for delays in the implementation of OF testing in regulated drug testing...

journal_title：Journal of analytical toxicology

authors： Samano KL,Anne L,Johnson T,Tang K,Sample RH

更新日期：2015-10-01 00:00:00

abstract：:Sampling and drug stability in oral fluid (OF) are crucial factors when interpreting forensic toxicological analysis, mainly because samples may not be analyzed immediately after collection, potentially altering drug concentrations. Therefore, the stability of some common drugs of abuse (morphine, codeine, 6-monoacety...

journal_title：Journal of analytical toxicology

authors： Marchei E,Malaca S,Graziano S,Gottardi M,Pichini S,Busardò FP

更新日期：2020-07-31 00:00:00