Expression of estrogen receptor-alpha and beta mRNA in the developing and adult mouse striatum.

abstract：:A digoxigenin-labeled antisense 42-mer oligonucleotide was used for the localization of the dopamine D2 receptor mRNA in the rat brain. The digoxigenin label was identified with alkaline phosphatase conjugated sheep-anti-digoxigenin. In good analogy with the known terminal fields of the dopaminergic system, various nu...

journal_title：Neuroscience letters

authors： Brouwer N,Van Dijken H,Ruiters MH,Van Willigen JD,Ter Horst GJ

更新日期：1992-08-17 00:00:00

abstract：:Fluorescent tracers (Nuclear Yellow, True Blue, Fast Blue) were injected, in various combinations, into the globus pallidus and substantia nigra in three marmosets. Examination of perikarya in the ipsilateral neostriatum, well removed from pallidal injection sites, revealed that the predominant pattern was of single-l...

journal_title：Neuroscience letters

authors： Féger J,Crossman AR

更新日期：1984-08-24 00:00:00

abstract：:The retrograde transport of receptor-bound opiate was markedly enhanced in the vagus nerves of rats housed for 25 days in an atmosphere of ethanol vapor. This increase disappeared after 8 days of withdrawal as did the animal preference for ethanol. In contrast, the axonal transport of muscarinic receptors in sciatic n...

journal_title：Neuroscience letters

authors： Laduron PM,De Witte PA

更新日期：1987-06-26 00:00:00

abstract：:Peroxisomal activities were examined in liver and brain of lactating neonatal rats of mothers maintained on ciprofibrate, a peroxisomal proliferator. The activities of DHAP-acyltransferase, alkyl-DHAP synthetase and the beta-oxidation of palmitic and lignoceric acids increased in brain by 3.9, 2.2, 4.3 and 3.2 fold an...

journal_title：Neuroscience letters

authors： Singh I,Lazo O

更新日期：1992-04-27 00:00:00

abstract：:Methylated beta-carboline compounds are mammalian indole metabolites that we have proposed to be endogenous neurotoxins due to their structural similarity to MPP+, the active oxidized product of the dopaminergic toxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Several laboratories have demonstrated that MPP...

journal_title：Neuroscience letters

authors： Neafsey EJ,Drucker G,Raikoff K,Collins MA

更新日期：1989-11-06 00:00:00

abstract：:Cognitive impairment in Parkinson's disease is accompanied by a marked decrease of cerebrocortical nicotinic receptors. To study the putative site of impaired receptor synthesis, frontal cortices of Parkinson patients with cognitive dysfunction have been screened for the expression of the nicotinic receptor alpha 4 su...

journal_title：Neuroscience letters

authors： Schröder H,de Vos RA,Jansen EN,Birtsch C,Wevers A,Lobron C,Nowacki S,Schröder R,Maelicke A

更新日期：1995-03-10 00:00:00

abstract：:To examine the effect of apolipoprotein E (ApoE) 4 on the progression of Alzheimer's disease (AD), the clinical course of 33 AD patients (17 cases with ApoE epsilon4 and 16 cases without ApoE epsilon4) was evaluated with the mini-mental state examination (MMSE) and cerebrospinal fluid (CSF) biological markers. The dec...

journal_title：Neuroscience letters

authors： Kanai M,Shizuka M,Urakami K,Matsubara E,Harigaya Y,Okamoto K,Shoji M

更新日期：1999-05-21 00:00:00

abstract：:We compared, for a number of ligands to the two receptors, the displacement of [3H]strychnine binding to the glycine-gated chloride channel of spinal cord and brainstem synaptic membranes to the displacement of [3H]glycine binding to the NMDA receptor complex of hippocampal and cortex synaptic membranes. Glycine and b...

journal_title：Neuroscience letters

authors： Pullan LM,Powel RJ

更新日期：1992-12-14 00:00:00

abstract：:The effects of myelin basic protein (MBP) on the ventral root response in rat spinal cord in situ and on the spontaneous bioelectric activity of cultured rat Purkinje cells were investigated. Injection of 2 or 4 microl MBP (10(-4) M/l) into the motoneurone pool reduced the ventral root response to dorsal root stimulat...

journal_title：Neuroscience letters

authors： Honegger CG,Gähwiler BH,Isler H

更新日期：1977-05-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is expressed in and defines a subset of motor neuron pools in the lumbar spinal cord of the chick embryo. The onset of CGRP expression in individual pools coincides with both the period of the initial innervation of the leg and the beginning of naturally occurring cell death in t...

journal_title：Neuroscience letters

authors： Mason IJ,Mudge AW

更新日期：1992-04-13 00:00:00

abstract：:The gamma-aminobutyric acid (GABA) antagonist (+/-)-bicuculline inhibits specific [3H]strychnine binding to postsynaptic glycine receptor sites in rat spinal cord synaptosomal membranes with an inhibition constant of about 5 microM, which is fairly similar to its inhibition constant reported for the GABA receptor. Thi...

journal_title：Neuroscience letters

authors： Goldinger A,Müller WE

更新日期：1980-01-01 00:00:00

abstract：:Cocaine's enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process. A large body of data indicates that opioids and dopamine together mediate emoti...

journal_title：Neuroscience letters

authors： Ambrose LM,Gallagher SM,Unterwald EM,Van Bockstaele EJ

更新日期：2006-05-22 00:00:00

abstract：:Current-voltage (I-V) relationships of glutamate receptors activated by the non-NMDA receptor agonist, kainate (KA), were determined in Xenopus laevis oocytes injected with either calf or chick brain mRNA. In most injected oocytes (n = 44; 84%), I-V plots to 80 microM KA exhibited inward rectification; however, in som...

journal_title：Neuroscience letters

authors： Bowie D,Smart TG

更新日期：1993-03-05 00:00:00

abstract：:Previous observations suggest a contribution of two APOE promoter polymorphisms (-219 G/T and -491 A/T) in dementia. From two independent populations of elderly (mean age of 84 and 85 years old, respectively), we observed that subjects bearing the -219T allele were at increased risk of dementia (OR = 1.9 (95% CI, 1.3-...

journal_title：Neuroscience letters

authors： Lambert JC,Berr C,Cottel D,Amouyel P,Helbecque N

更新日期：2004-07-22 00:00:00

abstract：:Human low back pain sometimes originates from lumbar facet joints. In human lumbar facet joint inflammation or degeneration, the referred pain is not only expanded into the low back area but also into the leg or foot. The rat L5-L6 facet joint is innervated by the L1-L5 dorsal root ganglia. The presence of brain-deriv...

journal_title：Neuroscience letters

authors： Ohtori S,Takahashi K,Moriya H

更新日期：2002-04-26 00:00:00

abstract：:The effect of 4-aminopyridine (4-AP) on long-term potentiation (LTP) was studied in the hippocampal slice preparation of the rat. Field excitatory postsynaptic potentials (EPSPs) were recorded and evoked in the stratum radiatum of the CA1. Both the low frequency EPSP and LTP of the EPSP were significantly increased by...

journal_title：Neuroscience letters

authors： Lee WL,Anwyl R,Rowan M

更新日期：1986-09-25 00:00:00

abstract：:We analyzed the participation of N-methyl-d-aspartate (NMDA) receptors in the neuronal damage caused by adult-onset hypothyroidism. Wistar rats were randomly assigned into four groups. The euthyroid group received tap water. The hypothyroid group received methimazole (60 mg/kg) in their drinking water to induce hypoth...

journal_title：Neuroscience letters

authors： Alva-Sánchez C,Becerril A,Anguiano B,Aceves C,Pacheco-Rosado J

更新日期：2009-04-10 00:00:00

abstract：:Although minocycline has been generally thought to have neuroprotective properties, the neuroprotective role of minocycline has not been investigated in the animal model of epilepsy. In this study, we investigated whether minocycline is neuroprotective against kainic acid (KA)-induced cell death through the caspase-de...

journal_title：Neuroscience letters

authors： Heo K,Cho YJ,Cho KJ,Kim HW,Kim HJ,Shin HY,Lee BI,Kim GW

更新日期：2006-05-08 00:00:00

abstract：:Nicotine is known to stimulate energy expenditure, although the precise mechanism is unclear. To clarify the involvement of corticotropin-releasing factor (CRF) in the mechanism by which nicotine increases energy expenditure, the effect of intraperitoneal injection of nicotine (0.1 or 0.5mg/kg) on the release of norad...

journal_title：Neuroscience letters

authors： Mano-Otagiri A,Iwasaki-Sekino A,Ohata H,Arai K,Shibasaki T

更新日期：2009-05-08 00:00:00

abstract：:Mild cognitive impairment (MCI) is a nosological entity proposed as an intermediate state between normal aging and dementia. MCI seems to represent an early stage of Alzheimer's disease (AD) and there is a great interest in the relationship between MCI and the progression to AD. Some studies have demonstrated an accum...

journal_title：Neuroscience letters

authors： Padurariu M,Ciobica A,Hritcu L,Stoica B,Bild W,Stefanescu C

更新日期：2010-01-18 00:00:00

abstract：:The extracellular signal-regulated kinase (ERK) is enriched in the central nervous system, including the dopamine responsive regions such as the striatum and medial prefrontal cortex (mPFC). The kinase is sensitive to changing cellular and synaptic input and is implicated in the regulation of synaptic transmission and...

journal_title：Neuroscience letters

authors： Mao LM,Wang JQ

更新日期：2019-04-23 00:00:00

abstract：:Retinal progenitor cells (RPCs) are an excellent resource for retinal replacement therapy, because they show enormous potential to differentiate into retinal-specific cell types. While the differentiating influence of serum has long been appreciated, the effects of serum concentration on RPC differentiation into speci...

journal_title：Neuroscience letters

authors： Hu Y,Ji J,Xia J,Zhao P,Fan X,Wang Z,Zhou X,Luo M,Gu P

更新日期：2013-02-08 00:00:00

abstract：:FasL has been shown to induce angiogenesis in vivo, however, the mechanism remains to be determined. We have previously shown that Fas ligation induces expression of chemokines such as interleukin-8 by human astrogliomas, which may partially explain the in vivo angiogenic property of FasL. Intercellular adhesion molec...

journal_title：Neuroscience letters

authors： Choi K,Benveniste EN,Choi C

更新日期：2003-11-27 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) and insulin promote the survival of 6-7 day old post-natal rat cerebellar granule cells. Previous studies using the PI3 kinase inhibitor, wortmannin and the over-expression of protein kinase B (PKB) have indicated that both PI3 kinase and PKB activation are central for insulin-...

journal_title：Neuroscience letters

authors： Foulstone EJ,Tavaré JM,Gunn-Moore FJ

更新日期：1999-04-02 00:00:00

abstract：:We examined the suggestion that some of the processes subserving learning through action-observation and motor-execution are different because sensory motor reafference is not available while the limb is at rest in the former condition. We confirmed the action-observation and motor-execution groups learned equally the...

journal_title：Neuroscience letters

authors： Hayes SJ,Andrew M,Elliott D,Roberts JW,Bennett SJ

更新日期：2012-01-11 00:00:00

abstract：:We have previously shown that mu-selective opioid agonists activate both an inward rectifying and a voltage-gated potassium conductance in acutely dissociated non-pyramidal neurons from rat hippocampus. We now report that the opioid-activated voltage-gated potassium conductance was blocked by the membrane permeable cA...

journal_title：Neuroscience letters

authors： Wimpey TL,Chavkin C

更新日期：1992-03-16 00:00:00

abstract：:The distributions of central amygdaloid nucleus (Ce) neurons projecting to different medullary regions were investigated using the retrograde transport of iontophoretically applied Fast Blue or bisbenzimide. Neurons projecting to the nucleus of the solitary tract were located throughout the medial, lateral and ventral...

journal_title：Neuroscience letters

authors： Thompson RL,Cassell MD

更新日期：1989-02-27 00:00:00

abstract：:To elucidate the early histopathological changes after transient focal cerebral ischemia, we made 1 h intraluminal occlusion of the middle cerebral artery on rats. After different reperfusion time, from minutes to 3 days, argyrophil III method was used for the demonstration of 'collapsed' (argyrophilic, dark) neurons....

journal_title：Neuroscience letters

authors： Czurkó A,Nishino H

更新日期：1993-11-12 00:00:00

abstract：:Electrical stimulation delivered to the rostral pons induced well coordinated activity of the intralaryngeal muscles and the ventilatory muscles for vocalization in unanesthetized, decerebrate cats. The stimulation reset the normal respiratory rhythm and induced vocalization with a newly developed rhythm. Continuous o...

journal_title：Neuroscience letters

authors： Sakamoto T,Yamanaka Y,Wada K,Nakajima Y

更新日期：1993-08-06 00:00:00

abstract：:Enterovirus infections of the central nervous system (CNS) are common and important causes of morbidity in immunocompromised children and adults. In this study we identify and characterize coxsackievirus B4-induced neuronal death. To investigate the CNS pathophysiology resulting from this viral infection, cultured rat...

journal_title：Neuroscience letters

authors： Joo CH,Kim YK,Lee H,Hong H,Yoon SY,Kim D

更新日期：2002-07-05 00:00:00