Abstract:
:It is proposed that there is biological regulation of the low molecular weight antioxidant (LMWA) status of the body, and that these different antioxidants work in concert and in homeostasis as a system analogous to the regulation of acid-base status (pH). The theoretical design characteristics for such a system include regulation, inducibility, interactivity and balance with the beneficial properties of reactive oxygen species. Testing the hypothesis requires developing suitable methodologies (such as measurement of the redox state) for assessing the total ratio of antioxidant to oxidant activity of both tissues and biological fluids, since it is not clear whether plasma antioxidant status reflects that of the tissues as well. This concept, if accepted, may help explain the contradictions relating to antioxidant therapy and lead to more rational recommendations for dietary intake. It may also help explain the effects of manipulating (increasing/decreasing) specific antioxidants on the overall antioxidant status in health and disease.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Berry EM,Kohen Rdoi
10.1054/mehy.1998.0786keywords:
subject
Has Abstractpub_date
1999-11-01 00:00:00pages
397-401issue
5eissn
0306-9877issn
1532-2777pii
S0306-9877(98)90786-1journal_volume
53pub_type
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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journal_title:Medical hypotheses
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abstract::The recent global pandemic created by the Coronavirus SARS-CoV-2, started in Wuhan, China in December 2019, has generated panic, both in term of human death (4-5% of infected patients identified through testing) and the global economy. Human sufferings seem to be continuing, and it is not clear how long this will cont...
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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更新日期:1983-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-06-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2008.04.020
更新日期:2008-09-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2000.1163
更新日期:2001-05-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2020.109790
更新日期:2020-04-24 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(85)90029-5
更新日期:1985-11-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2012.05.007
更新日期:2012-08-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2020.110178
更新日期:2020-11-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(89)90194-1
更新日期:1989-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2012.12.041
更新日期:2013-04-01 00:00:00
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pub_type: 历史文章,杂志文章
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更新日期:2018-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2009.03.007
更新日期:2009-08-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2011-09-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2006.04.070
更新日期:2006-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 社论,历史文章,评审
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更新日期:2010-05-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2010.09.028
更新日期:2011-02-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2019.109464
更新日期:2020-02-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(88)90112-0
更新日期:1988-05-01 00:00:00
abstract:AIMS:To investigate the role of urinary BK polyoma virus (BKPyV) in the pathophysiology and prognosis of patients with painful bladder syndrome/interstitial cystitis (PBS/IC). METHODS:Urine samples were collected from 15 patients with PBS/IC and 8 control patients (with urolithiasis, overactive bladder and benign pros...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2014.06.004
更新日期:2014-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0306-9877(93)90247-n
更新日期:1993-09-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2015.07.008
更新日期:2015-11-01 00:00:00