Abstract:
:With the increased availability of nitrite-containing commercial products that are used for the adulteration of urine samples in the workplace, it is necessary for laboratories to be able to detect and confirm the presence of nitrite in these samples. We have developed a method to confirm the presence of nitrite in urine samples. The method uses the IonPac AS 14 analytical column with the Dionex series 45001 Bio LC system equipped with an anion self-generating suppressor and conductivity detector. Using a single-point calibration, the method is linear and accurately quantitates nitrite to 12,000 microg/mL. The limit of detection is 30 microg/mL, and the day-to-day precision of the assay has a coefficient of variation (CV) of 4.3% at 1200 microg/mL and 3.8% at 2700 microg/mL of nitrite.
journal_name
J Anal Toxicoljournal_title
Journal of analytical toxicologyauthors
Singh J,Elberling JA,Hemphill DG,Holmstrom Jdoi
10.1093/jat/23.3.137keywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
137-40issue
3eissn
0146-4760issn
1945-2403journal_volume
23pub_type
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