Evaluation of the DrugCheck 9 on-site immunoassay test cup according to a standard method validation protocol.

abstract：:A study of the urinary concentration of fentanyl (F) and its major metabolite norfentanyl (NF) in chronic pain patients treated with the Duragesic continuous release transdermal patches is presented. These patches are available in 10, 20, 30, and 40 cm(2) sizes releasing 25, 50, 75, and 100 microg/h F, respectively. F...

journal_title：Journal of analytical toxicology

authors： Poklis A,Backer R

更新日期：2004-09-01 00:00:00

abstract：:Synthetic cathinones have recently emerged as a substitute for common drugs of abuse. Synthetic cathinones can elicit powerful adverse effects such as delusions, hallucinations and potentially dangerous behavior. To develop a method to analyze 10 synthetic cathinones in oral fluid, we implemented a combined approach o...

journal_title：Journal of analytical toxicology

authors： Amaratunga P,Lorenz Lemberg B,Lemberg D

更新日期：2013-11-01 00:00:00

abstract：:Urine drug testing is common for workplace drug testing, prescription management, emergency medicine and the criminal justice system. Unsurprisingly, with the significant consequences based upon the results of urine drug testing, a donor in need of concealing the contents of their sample is highly motivated to cheat t...

journal_title：Journal of analytical toxicology

authors： Goggin MM,Tann CM,Miller A,Nguyen A,Janis GC

更新日期：2017-03-01 00:00:00

abstract：:Benzoylecgonine (BZE) extraction from urine was explored using Cerex Polycrom Clin II solid-phase extraction (SPE) columns and the Speedisk 48 Pressure Processor as an alternative to the Prep1 automated sample processor and XTRX Type RP/W columns. Linearity for urine standards extracted using the Cerex-Speedisk method...

journal_title：Journal of analytical toxicology

authors： Kuhnle JA,Churley M,Kawasaki SY,Lyons TP,Bruins MR

更新日期：2001-10-01 00:00:00

abstract：:Since the introduction in 1990, the solid-phase microextraction (SPME) technology has brought significant progress in many fields of forensic sciences due to the versatility of this fast and solventless alternative to conventional extraction techniques. A systematic review about SPME applications in forensic context f...

journal_title：Journal of analytical toxicology

authors： De Giovanni N,Marchetti D

更新日期：2020-04-30 00:00:00

abstract：:At the end of 2010, the U.S. Drug Enforcement Administration (DEA) used its emergency scheduling authority to temporarily control five chemicals, JWH-018, JWH-073, JWH-200, CP-47497, and cannabicyclohexanol (CP-47497 C8), often referred to as "Spice", K2, or "synthetic cannabinoids" because of their reported cannabis-...

journal_title：Journal of analytical toxicology

authors： Coulter C,Garnier M,Moore C

更新日期：2011-09-01 00:00:00

abstract：:The metabolism of N-benzylpiperazine (BZP), a recently scheduled designer drug, in the rat has been studied by analyzing its urinary metabolites. p-Hydroxy-BZP (p-OH-BZP) was unequivocally identified as the main metabolite along with a minor metabolite m-hydroxy-BZP (m-OH-BZP), using gas chromatography-mass spectromet...

journal_title：Journal of analytical toxicology

authors： Tsutsumi H,Katagi M,Miki A,Shima N,Kamata T,Nakajima K,Inoue H,Kishi T,Tsuchihashi H

更新日期：2006-01-01 00:00:00

abstract：:Feces are a possible medium to be used for horse doping control. Efficient methods for detecting drugs in feces collected from various animals are routinely applied in institutes of food safety in Belgium. We have already tested whether they are applicable to horse feces. In this report, accelerated solvent extraction...

journal_title：Journal of analytical toxicology

authors： Popot MA,Donval A,Bonnaire Y,Huau J

更新日期：2006-06-01 00:00:00

abstract：:The abuse of the designer amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA) is increasing throughout the world. They have become popular drugs at all night techno dance parties, and their detection is an important issue. The objective of the presented study was to identify an unknown compound detected by t...

journal_title：Journal of analytical toxicology

authors： Maresova V,Hampl J,Chundela Z,Zrcek F,Polasek M,Chadt J

更新日期：2005-07-01 00:00:00

abstract：:This manuscript details a validated liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry (LC-APCI-MS-MS) method for the quantification of methadone and its metabolites 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) and 2-ethyl-5-methyl-3,3-diphenylpyroline (EMDP) in 0.5 mL ...

journal_title：Journal of analytical toxicology

authors： Choo RE,Jansson LM,Scheidweiler K,Huestis MA

更新日期：2007-06-01 00:00:00

abstract：:The Substance Abuse and Mental Health Services Administration (SAMHSA) is currently evaluating hydrocodone (HC) for inclusion in the Mandatory Guidelines for Federal Workplace Drug Testing Programs. This study evaluated the time course of HC, norhydrocodone (NHC), dihydrocodeine (DHC) and hydromorphone (HM) in paired ...

journal_title：Journal of analytical toxicology

authors： Cone EJ,DePriest AZ,Heltsley R,Black DL,Mitchell JM,LoDico C,Flegel R

更新日期：2015-09-01 00:00:00

abstract：:A high-performance liquid chromatographic method was used for the detection of etodolac in equine serum and urine. The method consisted of a one-step liquid-liquid extraction, separation on a reversed-phase (RP-18) column and detection using an ultraviolet detector. Additional confirmation methods included a HPLC coup...

journal_title：Journal of analytical toxicology

authors： Koupai-Abyazani MR,Esaw B,Laviolette B

更新日期：1999-05-01 00:00:00

abstract：:Carfentanil is a mu (μ) opioid receptor agonist and is estimated to be ~10,000 times more potent than morphine in animal (non-human) models. It is not approved for human use and is only used to immobilize large exotic animals in veterinary medicine. In mid-2016, carfentanil emerged as a contaminant in street heroin in...

journal_title：Journal of analytical toxicology

authors： Shanks KG,Behonick GS

更新日期：2017-07-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI), a still-emerging, non-invasive neuroimaging tool, has been applied to a wide range of questions in sensory, motor control, and cognitive psychology. Only more recently has it been applied to understand the sites and mechanisms of action of pharmacological agents within the...

journal_title：Journal of analytical toxicology

authors： Stein EA

更新日期：2001-07-01 00:00:00

abstract：:An isotope dilution gas chromatography-tandem mass spectrometric (GC-MS-MS) method was developed for quantitating the urinary metabolites of the organophosphorus nerve agents sarin, soman, tabun (GA), VX, and GF. Urine samples were concentrated by codistillation with acetonitrile, derivatized by methylation with diazo...

journal_title：Journal of analytical toxicology

authors： Driskell WJ,Shih M,Needham LL,Barr DB

更新日期：2002-01-01 00:00:00

abstract：:This study compares fluoride concentrations ([F]) in surface and whole bone for up to 27 days following an acute oral dose of F. Four groups of rats received single oral F dose (50 mg/kg body weight), and the control group received deionized water (n = 10/group). Groups were euthanized at 1, 3, 9, or 27 days after F a...

journal_title：Journal of analytical toxicology

authors： Buzalaf MA,Caroselli EE,de Carvalho JG,de Oliveira RC,da Silva Cardoso VE,Whitford GM

更新日期：2005-11-01 00:00:00

abstract：:Exemplars of current commercial breath-alcohol simulators were studied to ascertain their suitability for control tests and as calibrators in breath-alcohol analysis. Temperature, effluent volumes and pressures, effluent-alcohol concentration, and alcohol depletion were measured for simulators coupled with various cur...

journal_title：Journal of analytical toxicology

authors： Dubowski KM,Essary NA

更新日期：1991-09-01 00:00:00

abstract：:We described a simple procedure for the flash heater methylation of valproic acid and cyclohexylacetic acid (internal standard) by gas-liquid chromatography (GLC). A small volume (100 microL) of sample is acidified with 10% perchloric acid and extracted into hexane. An aliquot is back extracted into 5% tetramethylammo...

journal_title：Journal of analytical toxicology

authors： Calendrillo BA,Reynoso G

更新日期：1980-11-01 00:00:00

abstract：:A woman was alleged to have committed suicide by consuming a gasoline additive shortly before jumping from a second floor balcony within her home. She was found dead by police with a multitude of injuries, lying nude in a partially evaporated unknown residue that was later determined to be methanol. Samples collected ...

journal_title：Journal of analytical toxicology

authors： Avella J,Briglia E,Harleman G,Lehrer M

更新日期：2005-10-01 00:00:00

abstract：:Drug-facilitated sexual assault (DFSA) cases are pretty common in forensic toxicology. In this case report, a 56-year-old female tourist claimed to have been sexually assaulted by five men after having had a drug-spiked alcoholic drink. Urine samples were collected at 38, 44, and 45 hours after the alleged rape. After...

journal_title：Journal of analytical toxicology

authors： Carfora A,Campobasso CP,Cassandro P,Petrella R,Borriello R

更新日期：2020-11-12 00:00:00

abstract：:Phenazepam and etizolam were the first uncontrolled benzodiazepines available for sale in the UK. Pyrazolam, flubromazepam and diclazepam are not used medicinally anywhere in the world; they are produced exclusively for the uncontrolled, recreational market. It is important to know whether potentially abused drugs lik...

journal_title：Journal of analytical toxicology

authors： O'Connor LC,Torrance HJ,McKeown DA

更新日期：2016-03-01 00:00:00

abstract：:A rapid, specific and quantitative high-performance liquid chromatography assay procedure is described for the determination of ICI 125, 211, (I), a guanidino-thiazole H2-receptor antagonist, in small samples of animal plasma. A 0.2 mL aliquot of plasma is extracted at pH 9 with ethyl acetate. After reconstitution in ...

journal_title：Journal of analytical toxicology

authors： Monson K,Simon RK,Malbica JO

更新日期：1980-09-01 00:00:00

abstract：:Oxymorphone, a semi-synthetic opioid analgesic, has been available as Numorphan since the 1950s in the form of injectable solutions and a suppository. Recently, in 2006, oxymorphone was approved by the Federal Drug Administration for use in the form of immediate and extended release tablets under the trade name Opana....

journal_title：Journal of analytical toxicology

authors： Garside D,Hargrove RL,Winecker RE

更新日期：2009-04-01 00:00:00

abstract：:A microextraction by packed sorbent (MEPS) procedure for rapid concentration of methadone and its primary metabolite (EDDP) in hair samples was developed. The miniaturized approach coupled to gas chromatography with tandem mass spectrometry (GC-MS-MS) was successfully validated. Hair samples (50 mg) were incubated wit...

journal_title：Journal of analytical toxicology

authors： Rosado T,Gallardo E,Vieira DN,Barroso M

更新日期：2020-12-12 00:00:00

abstract：:Human exposure to organophosphate pesticides can be estimated from the presence of urinary metabolites. An isotope-dilution gas chromatography-tandem mass spectrometry (GC-MS-MS) method was developed for quantitating the six dialkyl phosphate urinary metabolites of at least 29 organophosphate pesticides. Urine samples...

journal_title：Journal of analytical toxicology

authors： Bravo R,Driskell WJ,Whitehead RD Jr,Needham LL,Barr DB

更新日期：2002-07-01 00:00:00

abstract：:In an effort to determine a practical, efficient, and economical alternative for the use of a radioimmunoassay (RIA) for the detection of lysergic acid diethylamide (LSD) in human urine, the performance of two photometric immunoassays (Dade Behring EMIT II and Microgenics CEDIA) and the Diagnostics Products Corp. (DPC...

journal_title：Journal of analytical toxicology

authors： Wiegand RF,Klette KL,Stout PR,Gehlhausen JM

更新日期：2002-10-01 00:00:00

abstract：:We devised a highly sensitive method for simultaneously determining methamphetamine (MA) and amphetamine (AP) enantiomers, desmethylselegiline (DMSG) and selegiline (SG), in human hair using a derivatization technique and high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS). M...

journal_title：Journal of analytical toxicology

authors： Nishida K,Itoh S,Inoue N,Kudo K,Ikeda N

更新日期：2006-05-01 00:00:00

abstract：:A forensic standard procedure is described that combines enzyme-linked immunoassay for screening and gas chromatography-mass spectrometry (GC-MS) for confirmation to detect drugs of abuse in a sample before used to detect opioids and cocaine. We used two equal aliquots of the same previously selected cannabinoid posit...

journal_title：Journal of analytical toxicology

authors： Tassoni G,Cippitelli M,Ottaviani G,Froldi R,Cingolani M

更新日期：2016-07-01 00:00:00

abstract：:The U.S. Drug Enforcement Administration has several different systems for collecting information on drugs of abuse. One is an early warning system, which collects information to provide scientific data and interpretation on drug abuse. Another is the collection of data from evidence submitted to DEA laboratories. Thi...

journal_title：Journal of analytical toxicology

authors： Frank RS

更新日期：1987-11-01 00:00:00

abstract：:A fatality due to the ingestion of isoniazid, a tuberculostatic agent, is presented. Isoniazid was extracted by a single step extraction procedure, derivatized with trifluoroacetic anhydride, and identified and quantified by gas chromatography/mass spectrometry (GC/MS). The distribution of isoniazid was as follows: he...

journal_title：Journal of analytical toxicology

authors： LoDico CP,Levine BS,Goldberger BA,Caplan YH

更新日期：1992-01-01 00:00:00