Extraction of benzoylecgonine from urine specimens with Cerex Polycrom Clin II solid-phase extraction columns and the Speedisk Pressure Processor.

abstract：:This study identified ethyl sulfate (EtS) in human urine and compared the excretion characteristics of EtS with that of ethanol and ethyl glucuronide (EtG). Urine samples were collected from healthy subjects after a single ethanol dose, and also selected from routine clinical samples. Simultaneous analysis of EtS and ...

journal_title：Journal of analytical toxicology

authors： Helander A,Beck O

更新日期：2005-07-01 00:00:00

abstract：:We present data from the analysis of the alcohol content of 391 beers and malt beverages available for sale in the State of Washington. The beverages were tested by gas chromatography for their alcohol content. Considerable variability in the alcoholic strength was found, even within the same class. Overall, the range...

journal_title：Journal of analytical toxicology

authors： Case GA,Distefano S,Logan BK

更新日期：2000-04-01 00:00:00

abstract：:A rapid and sensitive solid-phase extraction method for the lysergic acid diethylamide (LSD) metabolite 2-oxo-3-hydroxy-LSD (O-H-LSD) was developed for use in a forensic laboratory. The method uses a positive-pressure manifold anion-exchange polymer-based solid-phase extraction with subsequent analysis by liquid chrom...

journal_title：Journal of analytical toxicology

authors： Horn CK,Klette KL,Stout PR

更新日期：2003-10-01 00:00:00

abstract：:Exemplars of current commercial breath-alcohol simulators were studied to ascertain their suitability for control tests and as calibrators in breath-alcohol analysis. Temperature, effluent volumes and pressures, effluent-alcohol concentration, and alcohol depletion were measured for simulators coupled with various cur...

journal_title：Journal of analytical toxicology

authors： Dubowski KM,Essary NA

更新日期：1991-09-01 00:00:00

abstract：:Exposure to drugs and toxins is a major cause for the rising number of emergency department visits each year. Immunoassays are commonly used in the emergency department to provide rapid turnaround time for acute care. The purpose of this study was to compare two automated immunoassay chemistry analyzers to determine w...

journal_title：Journal of analytical toxicology

authors： Johnson-Davis KL,Thompson CD,Clark CJ,McMillin GA,Lehman CM

更新日期：2012-06-01 00:00:00

abstract：:Pharmacogenomics is the study of the linkage between an individual's genotype and the disposition of drugs in the body. The first association between adverse drug reactions and inherited variations was recognized in the 1950s, and since then, pharmacogenomics has come a long way. The importance of pharmacogenomics is ...

journal_title：Journal of analytical toxicology

authors： Kupiec TC,Raj V,Vu N

更新日期：2006-03-01 00:00:00

abstract：:Drug-facilitated sexual assault (DFSA) cases are pretty common in forensic toxicology. In this case report, a 56-year-old female tourist claimed to have been sexually assaulted by five men after having had a drug-spiked alcoholic drink. Urine samples were collected at 38, 44, and 45 hours after the alleged rape. After...

journal_title：Journal of analytical toxicology

authors： Carfora A,Campobasso CP,Cassandro P,Petrella R,Borriello R

更新日期：2020-11-12 00:00:00

abstract：:There has been a recent and significant increase in the use and availability of hemp seed oil products. These products are being marketed as a healthy source of essential omega fatty acids when taken orally. Although the health aspects of these oils is open to debate, the probability that oils derived from the hemp se...

journal_title：Journal of analytical toxicology

authors： Bosy TZ,Cole KA

更新日期：2000-10-01 00:00:00

abstract：:The aim of this study was to develop, optimize, and validate an analytical procedure to determine a group of eight amphetamines, amphetamine (AMP), ephedrine (EP), methcathinone (MTC), paramethoxyamphetamine (PMA), methamphetamine (MA), methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), and methyle...

journal_title：Journal of analytical toxicology

authors： Stanaszek R,Piekoszewski W

更新日期：2004-03-01 00:00:00

abstract：:Continuing our previous studies analyzing drugs of abuse in municipal wastewater, a method was developed for the analysis of opiates in wastewater samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS). Eight opiate drugs and metabolites were analyzed including codeine, hydrocodone, hydro...

journal_title：Journal of analytical toxicology

authors： Gul W,Stamper B,Godfrey M,Gul SW,ElSohly MA

更新日期：2016-06-01 00:00:00

abstract：:A new method was developed to apply the advantages of automated gas chromatographic headspace analysis to delayed measurement of alcohol in whole breath (W-B). End-expiratory breath and vapor-alcohol samples were collected in sealed, heated 22-mL glass vials, stored for 0-15 days, and thereafter analyzed for alcohol b...

journal_title：Journal of analytical toxicology

authors： Dubowski KM,Essary NA

更新日期：1982-09-01 00:00:00

abstract：:This study compares fluoride concentrations ([F]) in surface and whole bone for up to 27 days following an acute oral dose of F. Four groups of rats received single oral F dose (50 mg/kg body weight), and the control group received deionized water (n = 10/group). Groups were euthanized at 1, 3, 9, or 27 days after F a...

journal_title：Journal of analytical toxicology

authors： Buzalaf MA,Caroselli EE,de Carvalho JG,de Oliveira RC,da Silva Cardoso VE,Whitford GM

更新日期：2005-11-01 00:00:00

abstract：:Improvements have been made in recent years in on-site or point-of-care (POC) immunoassay testing devices. We evaluated the DrugCheck 9 cup, a new qualitative visually read, competitive binding, immunoassay cup that measures nine analytes. The study was performed according to the recent National Laboratory Certificati...

journal_title：Journal of analytical toxicology

authors： Taylor EH,Pizzo P

更新日期：2004-04-01 00:00:00

abstract：:A high-performance liquid chromatographic method has been developed for the simultaneous analysis of eight frequently used benzodiazepines and some of their metabolites in postmortem samples. The method includes a liquid-liquid extraction with n-hexane-ethyl acetate (70:30, v/v), gradient elution of a C8 reversed-phas...

journal_title：Journal of analytical toxicology

authors： Lambert WE,Meyer E,Xue-Ping Y,De Leenheer AP

更新日期：1995-01-01 00:00:00

abstract：:Data from previous experimental studies on the detection time of oxazepam and zopiclone in biological matrices are limited. The aim of this study was to examine the detection time in urine and oral fluid after single oral doses of oxazepam and zopiclone. Ten healthy volunteers received 25 mg of oxazepam in the evening...

journal_title：Journal of analytical toxicology

authors： Bruun LD,Kjeldstadli K,Temte V,Birdal M,Bachs L,Langødegård M,Strand DH,Gaare KI,Øiestad E,Høiseth G

更新日期：2019-06-01 00:00:00

abstract：:Results of urine drug analyses for three racing greyhounds that tested positive for caffeine in this laboratory were contested by the animal trainer, who asserted that positives were achieved from deliberate chocolate feeding by a rival kennel. The metabolism and excretion of methylxanthines was examined by high-perfo...

journal_title：Journal of analytical toxicology

authors： Wells DJ,Hanks BM,Yarbrough CS,Davis MA

更新日期：1988-01-01 00:00:00

abstract：:The misuse of the commonly used chemical diethylene glycol (DEG) has lead to many poisonings worldwide. Methods were developed for analysis of DEG and its potential metabolites; ethylene glycol, glycolic acid, oxalic acid, diglycolic acid and hydroxyethoxy acetic acid in human urine, serum and cerebrospinal fluid samp...

journal_title：Journal of analytical toxicology

authors： Perala AW,Filary MJ,Bartels MJ,McMartin KE

更新日期：2014-05-01 00:00:00

abstract：:From a public health point of view, cocaine (COC) presents serious clinical problems and deaths from overdose and lifelong addiction patterns, not to mention its involvement in crime, in the United States. This study subjected rhesus monkeys to one intravenous administration of COC (1 mg/kg), which closely imitates th...

journal_title：Journal of analytical toxicology

authors： Saady JJ,Bowman ER,Aceto MD

更新日期：1995-11-01 00:00:00

abstract：:Draft guidelines for the use of oral fluid for workplace drug testing are under development by the Substance Abuse and Mental Health Services Administration (SAMHSA) in cooperation with industry and researchers. Comparison studies of the effectiveness of oral fluid testing versus urine testing are needed to establish ...

journal_title：Journal of analytical toxicology

authors： Cone EJ,Presley L,Lehrer M,Seiter W,Smith M,Kardos KW,Fritch D,Salamone S,Niedbala RS

更新日期：2002-11-01 00:00:00

abstract：:Analysis of drugs in hair differs from their analysis in other tissues due to the extended detection window, as well as the opportunity that segmental hair analysis offers for the detection of changes in drug intake over time. The antipsychotic drug chlorprothixene is widely used, but few reports exist on chlorprothix...

journal_title：Journal of analytical toxicology

authors： Günther KN,Johansen SS,Wicktor P,Banner J,Linnet K

更新日期：2018-11-01 00:00:00

abstract：:Sixteen apparently intact procainamide tablets, in varied stages of drug depletion, were found distributed throughout the gastrointestinal tract of a man who died of arteriosclerotic heart disease with pulmonary complications. The tablets were found to contain procainamide by a thin layer chromatography system with ca...

journal_title：Journal of analytical toxicology

authors： Griesemer EC

更新日期：1984-09-01 00:00:00

abstract：:As a part of ongoing testing of personnel preparing training aids for drug detection dogs at the Naval Criminal Investigative Service Regional Forensic Laboratory, personnel handling methamphetamine (MTH) were subject to voluntary urine drug testing. This provided a model of potential unwitting or environmental exposu...

journal_title：Journal of analytical toxicology

authors： Stout PR,Horn CK,Klette KL,Given J

更新日期：2006-10-01 00:00:00

abstract：:Because mycotoxins occur worldwide in grain and grain products, evaluating their effects on the health of the population has become important. The development of a high performance liquid chromatographic (HPLC) procedure was investigated for the analysis of aflatoxin B1, citrinin, and ochratoxin A, from hydrolyzed hum...

journal_title：Journal of analytical toxicology

authors： Orti DL,Hill RH Jr,Liddle JA,Needham LL,Vickers L

更新日期：1986-03-01 00:00:00

abstract：:An original high-performance liquid chromatographic-mass spectrometric (HPLC-MS) procedure was developed for the determination of cyanide (CN) in whole blood. After the addition of K13C15N as internal standard, blood was placed in a microdiffusion device, the inner well of which was filled with a mixture of taurine (5...

journal_title：Journal of analytical toxicology

authors： Tracqui A,Raul JS,Géraut A,Berthelon L,Ludes B

更新日期：2002-04-01 00:00:00

abstract：:In cases of death by inert gas asphyxiation, it can be difficult to obtain toxicological evidence supporting assignment of a cause of death. Because of its low mass and high diffusivity, and its common use as a carrier gas, helium presents a particular challenge in this respect. We describe a rapid and simple gas chro...

journal_title：Journal of analytical toxicology

authors： Schaff JE,Karas RP,Marinetti L

更新日期：2012-03-01 00:00:00

abstract：:3,4-Methylenedioxypyrovalerone (MDPV) is a psychoactive, synthetic analog of the central nervous system stimulant cathinone. Its recent popularity as a recreational drug in the United States has led to numerous reports to poison control centers across the country. As with other synthetic cathinones, the recreational u...

journal_title：Journal of analytical toxicology

authors： Wyman JF,Lavins ES,Engelhart D,Armstrong EJ,Snell KD,Boggs PD,Taylor SM,Norris RN,Miller FP

更新日期：2013-04-01 00:00:00

abstract：:Pigmented (C57BI) and nonpigmented (balb/c) mice, 25 days of age, were treated intraperitoneally with [3H]-nicotine (4 mg/kg, 555 dpm/ng) or [3H]-flunitrazepam (1 mg/kg, 2200 dpm/ng) daily for three days. After 21 days, shaved back hair was digested at 37 degrees C for 24 h with either 1 M sodium hydroxide or 1 M sodi...

journal_title：Journal of analytical toxicology

authors： Claffey DJ,Stout PR,Ruth JA

更新日期：2000-01-01 00:00:00

abstract：:An analytical method for determining exposure to 2,2'-dichlorodiethyl sulfide (sulfur mustard, HD) has been enhanced. The method is based on the cleavage of adducted HD (protein-hydroxyethylthioethyl esters) to produce thiodiglycol. Following cleavage, a deuterated internal standard is added, and the analytes are extr...

journal_title：Journal of analytical toxicology

authors： Lawrence RJ,Smith JR,Boyd BL,Capacio BR

更新日期：2008-01-01 00:00:00

abstract：:To determine the degree of ethanol absorption and the resultant formation and urinary excretion of its conjugated metabolites following intensive use of high ethanol content mouthwash, 10 subjects gargled with Listerine(®) antiseptic 4 times daily for 3¼ days. First morning void urine specimens were collected on each ...

journal_title：Journal of analytical toxicology

authors： Reisfield GM,Goldberger BA,Pesce AJ,Crews BO,Wilson GR,Teitelbaum SA,Bertholf RL

更新日期：2011-06-01 00:00:00

abstract：:Analysis and interpretation of the findings for the drug of abuse gamma hydroxybutyric acid (GHB) in fatalities has become very problematic. This is primarily because of variable data in postmortem biological fluids resulting from the endogenous nature of the compound, possible postmortem production, and varying metho...

journal_title：Journal of analytical toxicology

authors： Elliott SP

更新日期：2004-01-01 00:00:00