Ethyl sulfate: a metabolite of ethanol in humans and a potential biomarker of acute alcohol intake.

abstract：:A high performance liquid chromatographic method is described for the simultaneous quantitation of four commonly prescribed antiarrhythmic drugs: lidocaine, mexiletine, disopyramide, and quinidine. An isocratic system using a reverse phase column was used to separate these compounds. Coefficients of variation were les...

journal_title：Journal of analytical toxicology

authors： Dusci LJ,Hackett LP

更新日期：1985-03-01 00:00:00

abstract：:cis(Z)-Clopenthixol and trans(E)-clopenthixol were determined by gas chromatography-mass spectrometry and high-performance liquid chromatography-diode-array detection in necropic samples from a postmortem case. The peripheral blood concentrations of cis(Z)-clopenthixol and trans(E)-clopenthixol were 278 and 177 ng/mL,...

journal_title：Journal of analytical toxicology

authors： Rop PP

更新日期：2001-07-01 00:00:00

abstract：:A method for the detection and quantitation of methamphetamine and its major metabolite in hair, nails, sweat, and saliva from habitual users of methamphetamine by mass fragmentography has been developed. Hair and nail samples were washed with water and methanol to remove the external contamination, processed with 0.6...

journal_title：Journal of analytical toxicology

authors： Suzuki S,Inoue T,Hori H,Inayama S

更新日期：1989-05-01 00:00:00

abstract：:The gelsemium plants are highly poisonous but toxicological evaluation of suspected poisoning cases has been hampered by the chemical complexity of the gelsemium toxins involved. A novel liquid chromatography-tandem mass spectrometry protocol was optimized for the collective detection of gelsemine and related alkaloid...

journal_title：Journal of analytical toxicology

authors： Lai CK,Chan YW

更新日期：2009-01-01 00:00:00

abstract：:Preliminary data regarding the use of vernix caseosa (VC) as an alternative to other biological specimens for the determination of fetal cocaine exposure are presented. Advantages of VC analysis include its presence on all newborn babies, historical record of drug exposure, and ease of collection and storage. Fifteen ...

journal_title：Journal of analytical toxicology

authors： Moore C,Dempsey D,Deitermann D,Lewis D,Leikin J

更新日期：1996-10-01 00:00:00

abstract：:There have been numerous reports of lead poisoning resulting from the ingestion of foreign bodies. A case involving the ingestion of spent air rifle pellets is described. No clinical symptoms were observed, despite the fact that the young child exhibited elevated blood lead levels as high as 2.7 micromol/L (56 microg/...

journal_title：Journal of analytical toxicology

authors： Treble RG,Thompson TS

更新日期：2002-09-01 00:00:00

abstract：:Fentanyl is a potent, short-acting narcotic analgesic widely used as a surgical anesthetic and for the control of pain when administered in the form of a transdermal patch. The success of the patch can be attributed to fentanyl's low molecular weight and its highly lipophilic nature, which enables it to be readily abs...

journal_title：Journal of analytical toxicology

authors： Anderson DT,Muto JJ

更新日期：2000-10-01 00:00:00

abstract：:We present an analytical method for the determination of heroin, free 6-acetylmorphine (6-AM), and free morphine in blood, urine, and vitreous humor. This method is used in postmortem cases where heroin is the suspected cause of death. The analytical protocol includes the following steps: liquid-liquid extraction at p...

journal_title：Journal of analytical toxicology

authors： Guillot JG,Lefebvre M,Weber JP

更新日期：1997-03-01 00:00:00

abstract：:A case report involving a 34-year-old white male who was found dead at home by his roommate is presented. At the time of his death, he was being treated with tramadol/acetaminophen, metaxalone, oxycodone, and amitriptyline. The decedent's mother stated that he had been taking increasing amounts of pain medication in o...

journal_title：Journal of analytical toxicology

authors： Bynum ND,Poklis JL,Gaffney-Kraft M,Garside D,Ropero-Miller JD

更新日期：2005-07-01 00:00:00

abstract：:Oxymorphone, a semi-synthetic opioid analgesic, has been available as Numorphan since the 1950s in the form of injectable solutions and a suppository. Recently, in 2006, oxymorphone was approved by the Federal Drug Administration for use in the form of immediate and extended release tablets under the trade name Opana....

journal_title：Journal of analytical toxicology

authors： Garside D,Hargrove RL,Winecker RE

更新日期：2009-04-01 00:00:00

abstract：:Urine drug testing (UDT) is an emerging standard of care in the evaluation and treatment of chronic non-cancer pain patients with opioid analgesics. UDT may be used both to verify adherence with the opioid analgesic regimen and to monitor abstinence from non-prescribed or illicit controlled substances. In the former s...

journal_title：Journal of analytical toxicology

authors： Bertholf RL,Johannsen LM,Reisfield GM

更新日期：2015-01-01 00:00:00

abstract：:At the end of 2010, the U.S. Drug Enforcement Administration (DEA) used its emergency scheduling authority to temporarily control five chemicals, JWH-018, JWH-073, JWH-200, CP-47497, and cannabicyclohexanol (CP-47497 C8), often referred to as "Spice", K2, or "synthetic cannabinoids" because of their reported cannabis-...

journal_title：Journal of analytical toxicology

authors： Coulter C,Garnier M,Moore C

更新日期：2011-09-01 00:00:00

abstract：:The Rapid Stat assay, a point-of-collection drug-testing device for detection of amphetamines, cannabinoids, cocaine, opiates, methadone, and benzodiazepines in oral fluid, was evaluated for cannabis and amphetamine-type stimulants. The Rapid Stat tests (n = 134) were applied by police officers in routine traffic chec...

journal_title：Journal of analytical toxicology

authors： Röhrich J,Zörntlein S,Becker J,Urban R

更新日期：2010-04-01 00:00:00

abstract：:We describe herewith the case of a patient presenting to the emergency department for worsening ear-nose-throat symptoms. As chemsex was evocated by the family, patient's serum was submitted to a new psychoactive substances screening. After a simple liquid liquid extraction, serum was injected on a high-resolution mas...

journal_title：Journal of analytical toxicology

authors： Deville M,Dubois N,Charlier C

更新日期：2020-11-04 00:00:00

abstract：:Gas chromatographic methods have been developed using a Supelco 1240-DA column for the determination of pentachlorophenol (PCP) in plasma and urine samples, and phenol in urine samples. These methods required no derivatization. Electron capture detection has been used for PCP determination, while flame ionization dete...

journal_title：Journal of analytical toxicology

authors： Rick DL,Licht CF,McCarty LP

更新日期：1982-11-01 00:00:00

abstract：:Since the introduction in 1990, the solid-phase microextraction (SPME) technology has brought significant progress in many fields of forensic sciences due to the versatility of this fast and solventless alternative to conventional extraction techniques. A systematic review about SPME applications in forensic context f...

journal_title：Journal of analytical toxicology

authors： De Giovanni N,Marchetti D

更新日期：2020-04-30 00:00:00

abstract：:The efficiency of ethanolamine and potassium hydroxide (KOH) as trapping agents for CO2 was determined using a flow of 500 mL/min through CO2 absorption towers containing trapping solutions. Radiolabeled 14CO2 was produced by acidification of suspensions containing Ba14CO3. Both 100% ethanolamine and 5M ethanolamine i...

journal_title：Journal of analytical toxicology

authors： Medinsky MA

更新日期：1986-01-01 00:00:00

abstract：:A rapid and simple method is described for the separation of quinidine (Q), its metabolites 3-hydroxyquinidine (30HQ) and 2'oxoquinidinone (QD) as well as the quinidine salt contaminant, dihydroquinidine (DHQ) in plasma by high pressure liquid chromatography (HPLC). A silica column was used with methanol: 1 N ammonium...

journal_title：Journal of analytical toxicology

authors： Pershing LK,Peat MA,Finkle BS

更新日期：1982-05-01 00:00:00

abstract：:The analysis of biological specimens collected at autopsy for the presence of exogenous insulin(s) is of special interest in select death investigations as they may be suspected in the cause of a death. Technical challenges include the limited stability of insulin, and the forensic requirement of differentiating endog...

journal_title：Journal of analytical toxicology

authors： Legg KM,Labay LM,Aiken SS,Logan BK

更新日期：2019-08-23 00:00:00

abstract：:An ultra-performance liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of 25 common pharmaceuticals in whole blood. The selected pharmaceuticals represent the most frequently detected drugs in our forensic laboratory with basic properties such as analgesics, antid...

journal_title：Journal of analytical toxicology

authors： Nielsen MK,Johansen SS

更新日期：2012-09-01 00:00:00

abstract：:Previous measurements of elemental concentrations in liver mitochondria have generally required homogenization and fractionation of liver tissue, a procedure in which it is difficult to rule out ion movement between subcellular units. New techniques involving cryoultramicrotomy of rapidly frozen tissue, high resolutio...

journal_title：Journal of analytical toxicology

authors： Millette JR,Allenspach AL,Clark PJ,McCauley PT,Washington IS

更新日期：1985-07-01 00:00:00

abstract：:Prolintane is a sympathomimetic amine with pharmacologic properties similar to d-amphetamine. Side effects include insomnia, nervousness, and irritability. Overdoses of prolintane may cause hallucinations, psychosis, and death. The drug is commonly prescribed in Africa, Australia, and Europe but is not available in th...

journal_title：Journal of analytical toxicology

authors： Kyle PB,Daley WP

更新日期：2007-09-01 00:00:00

abstract：:A method for determining the chemical warfare agent soman (GD) in rat plasma has been validated and applied to low-level inhalation exposure studies currently being conducted. This method utilizes a fluoride ion-based regeneration assay with isotope dilution followed by large volume injection gas chromatography with a...

journal_title：Journal of analytical toxicology

authors： Renner JA,Dabisch PA,Evans RA,McGuire JM,Totura AL,Jakubowski EM,Thomson SA

更新日期：2008-01-01 00:00:00

abstract：:Cyclopropylfentanyl is a fentanyl analog implicated in 78 deaths in Europe and over 100 deaths in the United States, but toxicological information including metabolism data about this drug is scarce. The aim of this study was to provide the exact structure of abundant and unique metabolites of cyclopropylfentanyl alon...

journal_title：Journal of analytical toxicology

authors： Vikingsson S,Rautio T,Wallgren J,Åstrand A,Watanabe S,Dahlén J,Wohlfarth A,Konradsson P,Wu X,Kronstrand R,Gréen H

更新日期：2019-09-10 00:00:00

abstract：:A 59-year-old white male accidentally ingested a mouthful of a plant growth chemical, Cycocel, containing 11.8% of the active ingredient (2-chloroethyl)trimethylammonium chloride (chlormequat). He was seen by a family physician and then transferred to a hospital where he died as a result of ventricular fibrillation, w...

journal_title：Journal of analytical toxicology

authors： Winek CL,Wahba WW,Edelstein JM

更新日期：1990-07-01 00:00:00

abstract：:Urine drug testing is common for workplace drug testing, prescription management, emergency medicine and the criminal justice system. Unsurprisingly, with the significant consequences based upon the results of urine drug testing, a donor in need of concealing the contents of their sample is highly motivated to cheat t...

journal_title：Journal of analytical toxicology

authors： Goggin MM,Tann CM,Miller A,Nguyen A,Janis GC

更新日期：2017-03-01 00:00:00

abstract：:The present study evaluates the suitability of headspace gas chromatography (GC) with a capillary column as a method for determining the ethanol content in different biological fluids. This procedure allows the use of headspace GC not only as a reference method but also in routine diagnostics and monitoring work. The ...

journal_title：Journal of analytical toxicology

authors： Macchia T,Mancinelli R,Gentili S,Lugaresi EC,Raponi A,Taggi F

更新日期：1995-07-01 00:00:00

abstract：:Continuing our previous studies analyzing drugs of abuse in municipal wastewater, a method was developed for the analysis of opiates in wastewater samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS). Eight opiate drugs and metabolites were analyzed including codeine, hydrocodone, hydro...

journal_title：Journal of analytical toxicology

authors： Gul W,Stamper B,Godfrey M,Gul SW,ElSohly MA

更新日期：2016-06-01 00:00:00

abstract：:This article reports the impact of diuresis on urinary excretion of ethanol in seven healthy volunteers who drank 1000 mL of export beer (44 g ethanol) in 30 min and, 120 min later, ingested 500 or 1000 mL of water within 5 min. Urine was voided before drinking started and every 30-60 min for 360 min after the start o...

journal_title：Journal of analytical toxicology

authors： Bendtsen P,Jones AW

更新日期：1999-11-01 00:00:00

abstract：:An original high-performance liquid chromatographic-mass spectrometric (HPLC-MS) procedure was developed for the determination of cyanide (CN) in whole blood. After the addition of K13C15N as internal standard, blood was placed in a microdiffusion device, the inner well of which was filled with a mixture of taurine (5...

journal_title：Journal of analytical toxicology

authors： Tracqui A,Raul JS,Géraut A,Berthelon L,Ludes B

更新日期：2002-04-01 00:00:00