Analysis of methamphetamine in hair, nail, sweat, and saliva by mass fragmentography.

abstract：:A gas chromatographic-chemical ionization mass spectrometric (GC-CIMS) method is described for the determination of cocaine, benzoylecgonine, and norcocaine. The procedure uses stable isotopes as internal standards and a mixture of methane-ammonia as chemical ionization reagent gas. Run-to-run and within-run coefficie...

journal_title：Journal of analytical toxicology

authors： Chinn DM,Crouch DJ,Peat MA,Finkle BS,Jennison TA

更新日期：1980-01-01 00:00:00

abstract：:A method is described for the simultaneous determination of the ratio of l- and d-enantiomers of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxyethylamphetamine (MDEA) in urine. The assay uses liquid-liquid extraction followed by deriv...

journal_title：Journal of analytical toxicology

authors： Hensley D,Cody JT

更新日期：1999-10-01 00:00:00

abstract：:A relatively simple procedure for the determination of carboxyhemoglobin percent saturation in postmortem samples is described. The procedure involves a quick and accurate method for calibration of the gas chromatograph to carbon monoxide. The mixed gases are extracted from blood prior to introduction into the gas chr...

journal_title：Journal of analytical toxicology

authors： Hobbs LD,Jachimczyk JA,Schloegel EL

更新日期：1980-07-01 00:00:00

abstract：:We present data from the analysis of the alcohol content of 391 beers and malt beverages available for sale in the State of Washington. The beverages were tested by gas chromatography for their alcohol content. Considerable variability in the alcoholic strength was found, even within the same class. Overall, the range...

journal_title：Journal of analytical toxicology

authors： Case GA,Distefano S,Logan BK

更新日期：2000-04-01 00:00:00

abstract：:A clinical study was designed to determine if there was a predictable relationship between saliva and plasma codeine concentrations. Drug-free volunteers (n = 17) were administered a 30-mg dose of liquid codeine phosphate. Plasma and saliva specimens were collected at various times for 24 h after administration. Plasm...

journal_title：Journal of analytical toxicology

authors： O'Neal CL,Crouch DJ,Rollins DE,Fatah A,Cheever ML

更新日期：1999-10-01 00:00:00

abstract：:Methoxphenidine (MXP, 2-MeO-diphenidine) is a dissociative anaesthetic drug of the diarylethylamine type, recently introduced for recreational purposes through the online-based sale of new psychoactive substances (NPS). The concentration of MXP in hair has never been reported, either in cases of chemsex use or in fata...

journal_title：Journal of analytical toxicology

authors： Goncalves R,Castaing N,Titier K,Dumestre-Toulet V

更新日期：2021-02-01 00:00:00

abstract：:The guidelines for screening of urinary cannabinoids require that all specimens testing positive should be confirmed by gas chromatography-mass spectrometry at a confirmatory test cutoff value of 15 ng/mL of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCCOOH). To assess the impact of lowering the confirmatory test cuto...

journal_title：Journal of analytical toxicology

authors： Lecompte Y,Perrin M,Salle S,Roussel O

更新日期：2012-10-01 00:00:00

abstract：:Bone was analyzed for ketamine and norketamine to examine whether different patterns of drug exposure could be discriminated. Rats received (intraperitoneally) one 75 mg/kg dose (Acute-1 and Acute-2 groups), three 25-mg/kg doses 1 hour apart (Repeated group), or nine single daily ketamine doses of 75 mg/kg followed by...

journal_title：Journal of analytical toxicology

authors： Watterson JH,Donohue JP,Betit CC

更新日期：2012-07-01 00:00:00

abstract：:Gas chromatographic-mass spectrometric (GC-MS) quantitation of 25 cannabis sed oils determined delta 9-tetrahydrocannabinol (THC) concentrations from 3 to 1500 micrograms/g oil. In a pilot study, the morning urine of six volunteers who had ingested 11 or 22 g of the oil, which contained the highest THC content (1500 m...

journal_title：Journal of analytical toxicology

authors： Lehmann T,Sager F,Brenneisen R

更新日期：1997-09-01 00:00:00

abstract：:Data from previous experimental studies on the detection time of oxazepam and zopiclone in biological matrices are limited. The aim of this study was to examine the detection time in urine and oral fluid after single oral doses of oxazepam and zopiclone. Ten healthy volunteers received 25 mg of oxazepam in the evening...

journal_title：Journal of analytical toxicology

authors： Bruun LD,Kjeldstadli K,Temte V,Birdal M,Bachs L,Langødegård M,Strand DH,Gaare KI,Øiestad E,Høiseth G

更新日期：2019-06-01 00:00:00

abstract：:Benzoylecgonine (BZE) extraction from urine was explored using Cerex Polycrom Clin II solid-phase extraction (SPE) columns and the Speedisk 48 Pressure Processor as an alternative to the Prep1 automated sample processor and XTRX Type RP/W columns. Linearity for urine standards extracted using the Cerex-Speedisk method...

journal_title：Journal of analytical toxicology

authors： Kuhnle JA,Churley M,Kawasaki SY,Lyons TP,Bruins MR

更新日期：2001-10-01 00:00:00

abstract：:A rapid and sensitive solid-phase extraction method for the lysergic acid diethylamide (LSD) metabolite 2-oxo-3-hydroxy-LSD (O-H-LSD) was developed for use in a forensic laboratory. The method uses a positive-pressure manifold anion-exchange polymer-based solid-phase extraction with subsequent analysis by liquid chrom...

journal_title：Journal of analytical toxicology

authors： Horn CK,Klette KL,Stout PR

更新日期：2003-10-01 00:00:00

abstract：:Selegiline (SE) is a selective, irreversible monoamine oxidase-B inhibitor, used for reducing symptoms in early-stage Parkinson's disease. The metabolites of SE include l-methamphetamine, l-amphetamine and desmethylselegiline (DSE). The stereoisomers of SE metabolites, d-methamphetamine and d-amphetamine are highly ad...

journal_title：Journal of analytical toxicology

authors： Shin I,Choi H,Kang S,Kim J,Park Y,Yang W

更新日期：2020-05-30 00:00:00

abstract：:The concentrations of amphetamine and methamphetamine in a new lyophilized human urine reference material (RM) were determined at the National Institute of Standards and Technology, in cooperation with the College of American Pathologists. In order to minimize the possibility of undetected bias, two different methods ...

journal_title：Journal of analytical toxicology

authors： Ellerbe P,Long T,Welch MJ

更新日期：1993-05-01 00:00:00

abstract：INTRODUCTION:We encountered unexpected false positive urine results in three patients for amphetamine-type substances by immunoassay, measured as part of community drug prevention programmes. Kavain was identified in all three urine samples by gas chromatography mass spectrometry (GC-MS). No other potential cross-react...

journal_title：Journal of analytical toxicology

authors： Madhavaram H,Patel T,Kyle C

更新日期：2020-12-16 00:00:00

abstract：:Synthetic cannabinoids are a group of compounds that are structurally diverse and are commonly found in various herbal incense and potpourri blends, which are sold in convenience stores, smoke shops and over the Internet. During the past few years, multiple state and federal legislations have been enacted controlling ...

journal_title：Journal of analytical toxicology

authors： Shanks KG,Behonick GS,Dahn T,Terrell A

更新日期：2013-10-01 00:00:00

abstract：:A preliminary investigation was undertaken to determine the feasibility of monitoring saliva levels of drugs for forensic purposes. Single oral doses of the title compounds were administered to healthy volunteers. Plasma and saliva levels were measured and ratios calculated for all drugs except diazepam. Saliva/plasma...

journal_title：Journal of analytical toxicology

authors： Sharp ME,Wallace SM,Hindmarsh KW,Peel HW

更新日期：1983-01-01 00:00:00

abstract：:Intoxications with the antifreeze constituent ethylene glycol (EG) occur infrequently, but may be fatal if not recognized and treated promptly. The aim of the present work was to develop an analytical method for rapid diagnosis of EG poisoning and for monitoring EG removal by hemodialysis. EG was measured by gas chrom...

journal_title：Journal of analytical toxicology

authors： Aarstad K,Dale O,Aakervik O,Ovrebø S,Zahlsen K

更新日期：1993-07-01 00:00:00

abstract：:Comprehensive investigation is necessary for determining the cause of death in cases with positive drug screens. We investigated the case of a male who reportedly expired from an acute asthma attack. He had limited access to both therapeutic drugs and drugs of abuse because he was a state prisoner. His autopsy was rem...

journal_title：Journal of analytical toxicology

authors： Merigian K,Blaho K

更新日期：1995-10-01 00:00:00

abstract：:About 22,000 samples of oral fluid have been collected in five population studies in Norway using either the Intercept or Statsure oral fluid sampling devices. The prevalence of alcohol and drugs was found to be higher in oral fluid samples with small volumes than in those with large volumes for both sampling devices;...

journal_title：Journal of analytical toxicology

authors： Gjerde H,Normann PT,Christophersen AS

更新日期：2010-09-01 00:00:00

abstract：:Amoxicillin has been causally linked in the lay and medical literature to false-positive urine drug screens for cocaine metabolites. An exhaustive search of the peer-reviewed medical literature revealed no data to support this link. We hypothesized that amoxicillin does not cause false-positive urine drug screens for ...

journal_title：Journal of analytical toxicology

authors： Reisfield GM,Haddad J,Wilson GR,Johannsen LM,Voorhees KL,Chronister CW,Goldberger BA,Peele JD,Bertholf RL

更新日期：2008-05-01 00:00:00

abstract：:Separating drugs which are both polar and basic has long been difficult because of the limited operating pH range of conventional HPLC columns. This paper describes a liquid chromatographic method capable of being used with either diode-array or mass spectrometric detection for the identification and quantitation of 1...

journal_title：Journal of analytical toxicology

authors： Goeringer KE,McIntyre lM,Drummer OH

更新日期：2003-01-01 00:00:00

abstract：:Gas chromatographic methods have been developed using a Supelco 1240-DA column for the determination of pentachlorophenol (PCP) in plasma and urine samples, and phenol in urine samples. These methods required no derivatization. Electron capture detection has been used for PCP determination, while flame ionization dete...

journal_title：Journal of analytical toxicology

authors： Rick DL,Licht CF,McCarty LP

更新日期：1982-11-01 00:00:00

abstract：:In this study, the relationships between the concentrations of R/S-methamphetamine (MA) and its metabolite R/S-amphetamine (AP), the AP/MA ratio in hair samples, and MA dependence were investigated by performing segmental hair analysis in MA users. Authentic hair samples collected from 10 chronic MA abusers were cut i...

journal_title：Journal of analytical toxicology

authors： Wang T,Shen B,Wu H,Gu J,Shen M,Xiang P

更新日期：2020-07-31 00:00:00

abstract：:Previous studies have shown that drug concentrations in blood can change during storage, especially at room temperature, but even labile drugs such as cocaine may be stable in dried blood spots (DBS). A new method has been developed for the analysis of hydrolytically labile drugs in blood spots on filter paper in orde...

journal_title：Journal of analytical toxicology

authors： Alfazil AA,Anderson RA

更新日期：2008-09-01 00:00:00

abstract：:In an effort to determine a practical, efficient, and economical alternative for the use of a radioimmunoassay (RIA) for the detection of lysergic acid diethylamide (LSD) in human urine, the performance of two photometric immunoassays (Dade Behring EMIT II and Microgenics CEDIA) and the Diagnostics Products Corp. (DPC...

journal_title：Journal of analytical toxicology

authors： Wiegand RF,Klette KL,Stout PR,Gehlhausen JM

更新日期：2002-10-01 00:00:00

abstract：:Urine drug testing is common for workplace drug testing, prescription management, emergency medicine and the criminal justice system. Unsurprisingly, with the significant consequences based upon the results of urine drug testing, a donor in need of concealing the contents of their sample is highly motivated to cheat t...

journal_title：Journal of analytical toxicology

authors： Goggin MM,Tann CM,Miller A,Nguyen A,Janis GC

更新日期：2017-03-01 00:00:00

abstract：:This paper describes two relatively simple methods for the microdetermination of urinary cadmium (U-Cd) and urinary nickel (U-Ni) using electrothermal atomic absorption spectrometry. Reduction of nonspecific absorption interferences was achieved by temperature programming and background correction using a deuterium ar...

journal_title：Journal of analytical toxicology

authors： Ong CN,Chua LH,Lee BL,Ong HY,Chia KS

更新日期：1990-01-01 00:00:00

abstract：:Postmortem findings are presented for fourteen cases of Verapamil induced or related deaths. Liver, blood, and stomach concentrations of Verapamil alone or in combination with alcohol or other drugs are given with the age and sex of each victim and with the coroner's findings. The significance of these levels is discu...

journal_title：Journal of analytical toxicology

authors： Chan LF,Chhuy LH,Crowley RJ

更新日期：1987-07-01 00:00:00

abstract：:The aim of this study was to investigate the early-phase postmortem redistribution of the enantiomers of citalopram (CIT) and its metabolites demethylcitalopram (DCIT) and didemethylcitalopram (DDCIT) in a rat model. Furthermore, we wanted to examine the role of the lungs as a reservoir of postmortem drug release and ...

journal_title：Journal of analytical toxicology

authors： Kugelberg FC,Kingbäck M,Carlsson B,Druid H

更新日期：2005-05-01 00:00:00