Abstract:
:About 22,000 samples of oral fluid have been collected in five population studies in Norway using either the Intercept or Statsure oral fluid sampling devices. The prevalence of alcohol and drugs was found to be higher in oral fluid samples with small volumes than in those with large volumes for both sampling devices; the largest differences were observed for tetrahydrocannabinol, alcohol, amphetamines, and cocaine/benzoylecgonine when using the Statsure device. Our recommendation is that samples of oral fluid with smaller volume than required by the analytical methods should not be discarded, but instead be analyzed using a smaller sample volume, if necessary, after dilution. If not analyzed, positive drug cases will be missed, and the total prevalence of alcohol and drugs in the population being studied will be underestimated.
journal_name
J Anal Toxicoljournal_title
Journal of analytical toxicologyauthors
Gjerde H,Normann PT,Christophersen ASdoi
10.1093/jat/34.7.416subject
Has Abstractpub_date
2010-09-01 00:00:00pages
416-9issue
7eissn
0146-4760issn
1945-2403journal_volume
34pub_type
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