Abstract:
:A case of lethal overdose by prilocaine, a local anaesthetic, is presented. The patient died in the dental office during treatment, and the time course of events was documented. The drug concentration in blood, urine, and liver was measured.
journal_name
J Anal Toxicoljournal_title
Journal of analytical toxicologyauthors
Kaliciak HA,Chan SCdoi
10.1093/jat/10.2.75subject
Has Abstractpub_date
1986-03-01 00:00:00pages
75-6issue
2eissn
0146-4760issn
1945-2403journal_volume
10pub_type
杂志文章abstract::N,N-Diethyl-m-toluamide (DEET) is an effective component of several insect repellent products. A 19-year-old woman was admitted to the emergency department following ingestion of 15-25 mL 95% diethyltoluamide (Muscol). Serum and urine toxicology screening tests were negative except for detection of DEET. DEET was qual...
journal_title:Journal of analytical toxicology
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journal_title:Journal of analytical toxicology
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journal_title:Journal of analytical toxicology
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更新日期:2006-01-01 00:00:00
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journal_title:Journal of analytical toxicology
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更新日期:2017-06-01 00:00:00
abstract::The method presented describes a sensitive and specific quantitative assay for the determination of flumazenil in human plasma. Flumazenil and an internal standard, midazolam, are isolated by a basic extraction. The final extract is separated on a 25-m BP-1 capillary column and drugs are detected by selected ion monit...
journal_title:Journal of analytical toxicology
pub_type: 杂志文章
doi:10.1093/jat/15.4.202
更新日期:1991-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/jat/14.5.325
更新日期:1990-09-01 00:00:00
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journal_title:Journal of analytical toxicology
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journal_title:Journal of analytical toxicology
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abstract::Ethylene glycol (EG), a relatively infrequent cause of fatal intoxication, presents an analytical challenge for forensic confirmation in postmortem toxicology. We report EG and glycolic acid (GA) quantification in postmortem blood by gas chromatography coupled with ion trap mass spectrometry (GC-MS) analysis using a m...
journal_title:Journal of analytical toxicology
pub_type: 杂志文章
doi:10.1093/jat/33.8.508
更新日期:2009-10-01 00:00:00
abstract::Pigmented (C57BI) and nonpigmented (balb/c) mice, 25 days of age, were treated intraperitoneally with [3H]-nicotine (4 mg/kg, 555 dpm/ng) or [3H]-flunitrazepam (1 mg/kg, 2200 dpm/ng) daily for three days. After 21 days, shaved back hair was digested at 37 degrees C for 24 h with either 1 M sodium hydroxide or 1 M sodi...
journal_title:Journal of analytical toxicology
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更新日期:2000-01-01 00:00:00
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journal_title:Journal of analytical toxicology
pub_type: 杂志文章
doi:10.1093/jat/13.1.8
更新日期:1989-01-01 00:00:00
abstract::We devised a highly sensitive method for simultaneously determining methamphetamine (MA) and amphetamine (AP) enantiomers, desmethylselegiline (DMSG) and selegiline (SG), in human hair using a derivatization technique and high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS). M...
journal_title:Journal of analytical toxicology
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journal_title:Journal of analytical toxicology
pub_type: 杂志文章
doi:10.1093/jat/11.5.210
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journal_title:Journal of analytical toxicology
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pub_type: 杂志文章
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abstract::A selective, sensitive, and reliable method was devised to determine concentrations of amitriptyline and its major metabolite, nortriptyline, in human plasma using high-performance liquid chromatography (HPLC) combined with UV and particle beam mass spectrometry (PBMS). Amitriptyline and nortriptyline were effectively...
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journal_title:Journal of analytical toxicology
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更新日期:2009-10-01 00:00:00
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journal_title:Journal of analytical toxicology
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journal_title:Journal of analytical toxicology
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journal_title:Journal of analytical toxicology
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
abstract::With the increased availability of nitrite-containing commercial products that are used for the adulteration of urine samples in the workplace, it is necessary for laboratories to be able to detect and confirm the presence of nitrite in these samples. We have developed a method to confirm the presence of nitrite in ur...
journal_title:Journal of analytical toxicology
pub_type: 杂志文章
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更新日期:1999-05-01 00:00:00
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journal_title:Journal of analytical toxicology
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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journal_title:Journal of analytical toxicology
pub_type: 杂志文章
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更新日期:1987-03-01 00:00:00
abstract::Methoxyacetylfentanyl and cyclopropylfentanyl are two of the newest illicit opioids that are infiltrating the heroin market. Methoxyacetylfentanyl and cyclopropylfentanyl were reported by the Drug Enforcement Administration (DEA) in their third quarter report of 2017 to have been chemically identified seven and five t...
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更新日期:2018-11-01 00:00:00
abstract::Publications reporting concentrations of caffeine in postmortem blood were reviewed if the cause of death was attributed to overdosing (poisoning) with drugs. Age and gender of the deceased, the manner of death (accident, suicide or undetermined) and types of co-ingested drugs were evaluated in relation to the concent...
journal_title:Journal of analytical toxicology
pub_type: 杂志文章,评审
doi:10.1093/jat/bkx011
更新日期:2017-04-01 00:00:00
abstract::Ethiofencarb is one of the carbamate compounds, which are, in general, less toxic than organophosphorus insecticides. This is due to their reversible acetylcholinesterase inhibition and relative inability to cross the blood-brain barrier. Generally, ethiofencarb is regarded to be of low toxicity (LD(50) > 200 mg/kg); ...
journal_title:Journal of analytical toxicology
pub_type: 杂志文章
doi:10.1093/jat/33.7.389
更新日期:2009-09-01 00:00:00