LC-MS-MS Method for Analysis of Opiates in Wastewater During Football Games II.

abstract：:Urine specimens containing 11 common beta blockers were processed using solid-phase extraction technology to extract the drugs from the urine matrix, then converted to their cyclic methaneboronates by treatment with methaneboronic acid in ethyl acetate. The compounds tested included acebutolol, atenolol, alprenolol, b...

journal_title：Journal of analytical toxicology

authors： Branum GD,Sweeney S,Palmeri A,Haines L,Huber C

更新日期：1998-03-01 00:00:00

abstract：:A simple and efficient method, based on the adsorption properties of octadecasilane bonded silica, is described for the rapid extraction of acidic drugs from whole post mortem blood. The blood was diluted, passed through an extraction column containing the bonded silica and the absorbed drugs were eluted with methanol...

journal_title：Journal of analytical toxicology

authors： Ford B,Vine J,Watson TR

更新日期：1983-05-01 00:00:00

abstract：:In cases of death by inert gas asphyxiation, it can be difficult to obtain toxicological evidence supporting assignment of a cause of death. Because of its low mass and high diffusivity, and its common use as a carrier gas, helium presents a particular challenge in this respect. We describe a rapid and simple gas chro...

journal_title：Journal of analytical toxicology

authors： Schaff JE,Karas RP,Marinetti L

更新日期：2012-03-01 00:00:00

abstract：:Gas chromatographic methods have been developed using a Supelco 1240-DA column for the determination of pentachlorophenol (PCP) in plasma and urine samples, and phenol in urine samples. These methods required no derivatization. Electron capture detection has been used for PCP determination, while flame ionization dete...

journal_title：Journal of analytical toxicology

authors： Rick DL,Licht CF,McCarty LP

更新日期：1982-11-01 00:00:00

abstract：:The present study evaluates the suitability of headspace gas chromatography (GC) with a capillary column as a method for determining the ethanol content in different biological fluids. This procedure allows the use of headspace GC not only as a reference method but also in routine diagnostics and monitoring work. The ...

journal_title：Journal of analytical toxicology

authors： Macchia T,Mancinelli R,Gentili S,Lugaresi EC,Raponi A,Taggi F

更新日期：1995-07-01 00:00:00

abstract：:With the increased availability of nitrite-containing commercial products that are used for the adulteration of urine samples in the workplace, it is necessary for laboratories to be able to detect and confirm the presence of nitrite in these samples. We have developed a method to confirm the presence of nitrite in ur...

journal_title：Journal of analytical toxicology

authors： Singh J,Elberling JA,Hemphill DG,Holmstrom J

更新日期：1999-05-01 00:00:00

abstract：:Urine drug testing (UDT) is an emerging standard of care in the evaluation and treatment of chronic non-cancer pain patients with opioid analgesics. UDT may be used both to verify adherence with the opioid analgesic regimen and to monitor abstinence from non-prescribed or illicit controlled substances. In the former s...

journal_title：Journal of analytical toxicology

authors： Bertholf RL,Johannsen LM,Reisfield GM

更新日期：2015-01-01 00:00:00

abstract：:Phenazepam and etizolam were the first uncontrolled benzodiazepines available for sale in the UK. Pyrazolam, flubromazepam and diclazepam are not used medicinally anywhere in the world; they are produced exclusively for the uncontrolled, recreational market. It is important to know whether potentially abused drugs lik...

journal_title：Journal of analytical toxicology

authors： O'Connor LC,Torrance HJ,McKeown DA

更新日期：2016-03-01 00:00:00

abstract：:Prolintane is a sympathomimetic amine with pharmacologic properties similar to d-amphetamine. Side effects include insomnia, nervousness, and irritability. Overdoses of prolintane may cause hallucinations, psychosis, and death. The drug is commonly prescribed in Africa, Australia, and Europe but is not available in th...

journal_title：Journal of analytical toxicology

authors： Kyle PB,Daley WP

更新日期：2007-09-01 00:00:00

abstract：:A sensitive and specific method for the quantitative determination of D,L-methadone (MD) and its metabolites, D,L-2-ethyl-1,5-dimethyl-3, 3-diphenylpyrrolinium (EDDP) and D,L-2-ethyl-5-methyl-3, 3-diphenyl-1-pyrroline (EMDP), in hair has been developed. Deuterated internal standards of MD, EMDP, and EDDP were added to...

journal_title：Journal of analytical toxicology

authors： Wilkins DG,Nagasawa PR,Gygi SP,Foltz RL,Rollins DE

更新日期：1996-10-01 00:00:00

abstract：:Results of urine drug analyses for three racing greyhounds that tested positive for caffeine in this laboratory were contested by the animal trainer, who asserted that positives were achieved from deliberate chocolate feeding by a rival kennel. The metabolism and excretion of methylxanthines was examined by high-perfo...

journal_title：Journal of analytical toxicology

authors： Wells DJ,Hanks BM,Yarbrough CS,Davis MA

更新日期：1988-01-01 00:00:00

abstract：:A 59-year-old white male accidentally ingested a mouthful of a plant growth chemical, Cycocel, containing 11.8% of the active ingredient (2-chloroethyl)trimethylammonium chloride (chlormequat). He was seen by a family physician and then transferred to a hospital where he died as a result of ventricular fibrillation, w...

journal_title：Journal of analytical toxicology

authors： Winek CL,Wahba WW,Edelstein JM

更新日期：1990-07-01 00:00:00

abstract：:The post mortem findings of pentazocine and tripelennamine ("T's and Blues") in abusers dying in the City of St. Louis between July 1, 1979 and July 30, 1981 are presented. Thirty-three deaths were homicides; 30 black males, ages 21-38; one white male, age 26, died from gunshot wounds; and two black females, age 18 an...

journal_title：Journal of analytical toxicology

authors： Poklis A,Mackell MA

更新日期：1982-05-01 00:00:00

abstract：:An automated column-switching liquid chromatographic-atmospheric pressure chemical ionization-mass spectrometric (LC-APCI-MS) method for the simultaneous determination of frequently encountered benzodiazepine hypnotics and their relevant metabolites in urine has been established. A column-switching online solid-phase ...

journal_title：Journal of analytical toxicology

authors： Miki A,Tatsuno M,Katagi M,Nishikawa M,Tsuchihashi H

更新日期：2002-03-01 00:00:00

abstract：:The relationship between blood cocaine concentrations and pharmacological effects is of both theoretical and practical interest. This study utilized a computer-assisted smoking device for the delivery of three active doses (10, 20, and 40 mg) of cocaine base to seven human volunteers. Doses were administered in an asc...

journal_title：Journal of analytical toxicology

authors： Jenkins AJ,Keenan RM,Henningfield JE,Cone EJ

更新日期：2002-10-01 00:00:00

abstract：:This study of 20,089 urine specimens from chronic pain patients provided a unique opportunity to evaluate the prevalence of prescription opiates and metabolites, assess the usefulness of inclusion of normetabolites in the test panel, and compare opiate and oxycodone screening results to liquid chromatography with tand...

journal_title：Journal of analytical toxicology

authors： Heltsley R,Zichterman A,Black DL,Cawthon B,Robert T,Moser F,Caplan YH,Cone EJ

更新日期：2010-01-01 00:00:00

abstract：:There have been numerous reports of lead poisoning resulting from the ingestion of foreign bodies. A case involving the ingestion of spent air rifle pellets is described. No clinical symptoms were observed, despite the fact that the young child exhibited elevated blood lead levels as high as 2.7 micromol/L (56 microg/...

journal_title：Journal of analytical toxicology

authors： Treble RG,Thompson TS

更新日期：2002-09-01 00:00:00

abstract：:A case report involving a 34-year-old white male who was found dead at home by his roommate is presented. At the time of his death, he was being treated with tramadol/acetaminophen, metaxalone, oxycodone, and amitriptyline. The decedent's mother stated that he had been taking increasing amounts of pain medication in o...

journal_title：Journal of analytical toxicology

authors： Bynum ND,Poklis JL,Gaffney-Kraft M,Garside D,Ropero-Miller JD

更新日期：2005-07-01 00:00:00

abstract：:The Connecticut Department of Public Safety laboratory recently addressed a legal challenge to a hospital alcohol dehydrogenase (ADH)-based serum ethanol determination based on the suggestion of interference by lactate dehydrogenase (LDH)-catalyzed oxidation of lactate. Both ADH- and LDH-oxidations require NAD(+) (pre...

journal_title：Journal of analytical toxicology

authors： Powers RH,Dean DE

更新日期：2009-10-01 00:00:00

abstract：:A method utilizing microwave dissolution in a closed Teflon bomb followed by hydride generation atomic absorption spectrometry has been used for the routine analysis of arsenic in fish species from the coast of the province of Granada, Spain. The technique was evaluated for decomposing biological standard reference ma...

journal_title：Journal of analytical toxicology

authors： Navarro M,López H,López MC,Sánchez M

更新日期：1992-05-01 00:00:00

abstract：:The aim of this study is to investigate the concentrations of ethyl glucuronide (EtG) in oral fluid and both EtG and ethyl sulfate (EtS) in blood and urine following intense use of mouthwash and ingestion of nonalcoholic wine, which are proven to contain 3 mg/L EtG, 1.5 mg/L EtS, and 0.2 g/L ethanol. Twelve subjects p...

journal_title：Journal of analytical toxicology

authors： Høiseth G,Yttredal B,Karinen R,Gjerde H,Christophersen A

更新日期：2010-03-01 00:00:00

abstract：:Bleach, nitrite, chromate, and hydrogen peroxide-peroxidase are effective urine adulterants used by the illicit drug users to conceal marijuana-positive results. Methods for detecting nitrite and chromate are available. Effects of other oxidizing agents that could possibly be used as adulterants and are difficult to d...

journal_title：Journal of analytical toxicology

authors： Paul BD,Jacobs A

更新日期：2002-10-01 00:00:00

abstract：:A sensitive method for identifying and quantifying brucine by means of liquid chromatography-tandem mass spectrometry is presented in this article. Based on a solid-phase extraction for human serum, the validation indicated limits of detection and quantification of 0.12 and 0.23 ng/mL, respectively. In one case of let...

journal_title：Journal of analytical toxicology

authors： Teske J,Weller JP,Albrecht UV,Fieguth A

更新日期：2011-05-01 00:00:00

abstract：:A sensitive and reproducible gas chromatographic procedure for the quantitative determination of urinary o-cresol is described. The first step involves acid hydrolysis (2N HCl, 100 degrees C, 10 min), which yields unconjugated o-cresol. After extraction (methylene chloride, pH 2), the organic layer is concentrated by ...

journal_title：Journal of analytical toxicology

authors： Truchon G,Tardif R,Brodeur J

更新日期：1996-09-01 00:00:00

abstract：:An original high-performance liquid chromatographic-mass spectrometric (HPLC-MS) procedure was developed for the determination of cyanide (CN) in whole blood. After the addition of K13C15N as internal standard, blood was placed in a microdiffusion device, the inner well of which was filled with a mixture of taurine (5...

journal_title：Journal of analytical toxicology

authors： Tracqui A,Raul JS,Géraut A,Berthelon L,Ludes B

更新日期：2002-04-01 00:00:00

abstract：:Carfentanil is a mu (μ) opioid receptor agonist and is estimated to be ~10,000 times more potent than morphine in animal (non-human) models. It is not approved for human use and is only used to immobilize large exotic animals in veterinary medicine. In mid-2016, carfentanil emerged as a contaminant in street heroin in...

journal_title：Journal of analytical toxicology

authors： Shanks KG,Behonick GS

更新日期：2017-07-01 00:00:00

abstract：:A 5-mg dose of cocaine free base applied to the volar forearm skin surface of a volunteer resulted in a maximal urinary benzoylecgonine concentration of 55 ng/mL at 48 h, using discrete urine specimens. A total of 58 micrograms of benzoylecgonine, representing 1.2% of the dose, was excreted in the 96-h urine. An ident...

journal_title：Journal of analytical toxicology

authors： Baselt RC,Chang JY,Yoshikawa DM

更新日期：1990-11-01 00:00:00

abstract：:A fatal case attributed to flecainide intoxication is presented. Quantitation was by capillary gas chromatography with nitrogen-phosphorus detection. The flecainide concentration in the blood was 13 mg/L as compared to a therapeutic range in serum of 0.2-1.0 mg/L. Flecainide concentrations in other specimens were as f...

journal_title：Journal of analytical toxicology

authors： Levine B,Chute D,Caplan YH

更新日期：1990-09-01 00:00:00

abstract：:Despite the efforts to prevent the spread of new psychoactive substances (NPS) such as synthetic amphetamine derivatives, it is apparent that newer types of NPS are still emerging on the market in recent years. Due to high potential for their abuse, reliable analytical methods are required to determine these substance...

journal_title：Journal of analytical toxicology

authors： Kim JY,Suh S,Park J,In MK

更新日期：2018-11-01 00:00:00

abstract：:A variety of chemical agents were evaluated to determine their effects on fluorescence polarization immunoassays for drugs of abuse. Sixteen different agents, at concentrations up to 10%, were tested against urine assays for cannabinoids, cocaine (metabolite), amphetamines, opiates, phencyclidine (PCP), and barbiturat...

journal_title：Journal of analytical toxicology

authors： Schwarzhoff R,Cody JT

更新日期：1993-01-01 00:00:00