Abstract：
:Susac's Syndrome (SS) is an autoimmune endotheliopathy of cerebral, retinal and cochlear arterioles. We report of an HIV-infected woman who developed a first SS episode following a spontaneous reduction of plasma viral load and several relapses six years later, following initiation of combined antiretroviral therapy (cART). Corticosteroids and intravenous immunoglobulins alone did not control the disease, which improved after combined treatment with acyclovir and ganciclovir. SS onset in HIV infection and relapses during cART-induced immune reconstitution are consistent with the dysimmune nature of the disease. The response to anti-herpes drugs suggests a viral contribute in this case of SS.
journal_name
AIDS Res Therjournal_title
AIDS research and therapyauthors
Ferretti F,Gerevini S,Colombo B,Testa M,Guffanti M,Franciotta D,Bernardi G,Lazzarin A,Cinque Pdoi
10.1186/1742-6405-10-22subject
Has Abstractpub_date
2013-09-03 00:00:00pages
22issue
1issn
1742-6405pii
1742-6405-10-22journal_volume
10pub_type
杂志文章abstract：:BACKGROUND: RNA interference (RNAi) mediated by small interfering RNAs (siRNAs) has proved to be a highly effective gene silencing mechanism with great potential for HIV/AIDS gene therapy. Previous work with siRNAs against cellular coreceptors CXCR4 and CCR5 had shown that down regulation of these surface molecules co...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-2-1
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-3-29
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-9-14
更新日期：2012-05-14 00:00:00
abstract：BACKGROUND:The population of HIV replicating within a host consists of independently evolving and interacting sub-populations that can be genetically distinct within anatomical compartments. HIV replicating within the brain causes neurocognitive disorders in up to 20-30% of infected individuals and is a viral sanctuary...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-7-43
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abstract：BACKGROUND:Drug resistance testing before initiation of, or during, antiretroviral therapy (ART) is not routinely performed in resource-limited settings. High levels of viral resistance circulating within the population will have impact on treatment programs by increasing the chances of transmission of resistant strain...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-8-38
更新日期：2011-10-13 00:00:00
abstract：BACKGROUND:About 13 years since the introduction of antiretroviral therapy (ART) for children living with HIV (CLHIV) in Zambia, HIV/AIDS testing and treatment guidelines for children have evolved over the years with limited documentation of long-term trends in the numbers testing HIV positive and initiating ART. We ex...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-020-00277-0
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abstract：BACKGROUND:To describe the development and the psychometric properties of the Istituto Superiore di Sanità-HIV symptoms scale (lSS-HIV symptoms scale). METHODS:The ISS-HIV symptom scale was developed by an Italian working team including researchers, physicians and people living with HIV. The development process went t...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-016-0102-2
更新日期：2016-04-09 00:00:00
abstract：: In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred during a phase of uncontrolled viral replication combined with a severe immunodeficiency and resolved by an effect...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-8-9
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVES:To compare outcomes with single tablet regimens (STR) versus multi-tablet regimens (MTR) for human immunodeficiency virus (HIV) treatment using published data. DESIGN:Systematic review and random-effects meta-analysis of literature on approved and investigational HIV regimens. METHODS:The research followed...
journal_title：AIDS research and therapy
pub_type： 杂志文章,meta分析
doi：10.1186/s12981-018-0204-0
更新日期：2018-10-30 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-015-0076-5
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-017-0140-4
更新日期：2017-03-14 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章,评审
doi：10.1186/s12981-017-0162-y
更新日期：2017-07-26 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-7-40
更新日期：2010-11-23 00:00:00
abstract：BACKGROUND:HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission. METHODS:We modeled two scenarios to measure the impact of adult ART use on the incidence of orphanhood ...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-8-13
更新日期：2011-03-07 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-3-16
更新日期：2006-05-26 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章,评审
doi：10.1186/s12981-016-0114-y
更新日期：2016-09-13 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-8-30
更新日期：2011-08-16 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-9-7
更新日期：2012-03-12 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-016-0108-9
更新日期：2016-07-25 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-11-6
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journal_title：AIDS research and therapy
pub_type： 临床试验,杂志文章
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-7-25
更新日期：2010-07-23 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-018-0202-2
更新日期：2018-10-27 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-020-00275-2
更新日期：2020-05-13 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-7-11
更新日期：2010-05-24 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-018-0214-y
更新日期：2019-01-21 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-017-0186-3
更新日期：2017-11-13 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-015-0058-7
更新日期：2015-05-10 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-2-3
更新日期：2005-04-28 00:00:00
abstract：BACKGROUND:Tubular dysfunction is common in HIV-infected people and detection of proteinuria is essential to identify this problem. In low-income countries, resources for detection of proteinuria using the Kidney Disease Improve Global Outcomes (KDIGO) gold standard urinary protein/creatinine ratio (uPCR) is rarely pos...
journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-015-0047-x
更新日期：2015-03-21 00:00:00
