Non-AIDS defining cancer (NADC) among HIV-infected patients at an oncology tertiary-care center in Mexico.

abstract：BACKGROUND:The population of HIV replicating within a host consists of independently evolving and interacting sub-populations that can be genetically distinct within anatomical compartments. HIV replicating within the brain causes neurocognitive disorders in up to 20-30% of infected individuals and is a viral sanctuary...

journal_title：AIDS research and therapy

authors： Holman AG,Mefford ME,O'Connor N,Gabuzda D

更新日期：2010-12-14 00:00:00

abstract：UNLABELLED: BACKGROUND:The high cost of CD4 count estimation in resource-limited countries is a major challenge in initiating patients on highly active antiretroviral therapy (HAART). Therefore, assessment of inexpensive and simple laboratory diagnostic marker is mandatory to diagnose immuno-suppression. OBJECTIVE:To...

journal_title：AIDS research and therapy

authors： Wondimeneh Y,Ferede G,Yismaw G,Muluye D

更新日期：2012-07-15 00:00:00

abstract：BACKGROUND:Most in vitro assays of drug potency may not adequately predict the performance in vivo. Methods to assess the persistence of antiviral activity of deoxynucleoside analogs, which require intracellular activation to the active metabolites that can persist in cells, will be important for designing dosages, com...

journal_title：AIDS research and therapy

authors： Paintsil E,Grill SP,Dutschman GE,Cheng YC

更新日期：2009-04-22 00:00:00

abstract：BACKGROUND:Separately, chronic alcohol ingestion and HIV-1 infection are associated with severe skeletal muscle derangements, including atrophy and wasting, weakness, and fatigue. One prospective cohort study reported that 41% of HIV-infected patients met the criteria for alcoholism, however; few reports exist on the c...

journal_title：AIDS research and therapy

authors： Clary CR,Guidot DM,Bratina MA,Otis JS

更新日期：2011-08-16 00:00:00

abstract：PURPOSE:To evaluate psychometric characteristics and cross-sectional and longitudinal validity of the 7-item PROMIS® Fatigue Short Form and additional fatigue items among people living with HIV (PLWH) in a nationally distributed network of clinics collecting patient reported data at the time of routine clinical care. ...

journal_title：AIDS research and therapy

authors： Gibbons LE,Fredericksen R,Batey DS,Dant L,Edwards TC,Mayer KH,Mathews WC,Morales LS,Mugavero MJ,Yang FM,Paez E,Kitahata MM,Patrick DL,Crane HM,Crane PK,Centers for AIDS Research Network of Integrated Clinical Systems (CNICS

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Varicella-zoster virus (VZV) reactivation is common but difficult to predict in HIV-infected persons. OBJECTIVE:Since qualitative VZV antibodies can determine past VZV disease or vaccination, we evaluated whether quantitative VZV antibody levels over time can predict future zoster. STUDY DESIGN:US Military...

journal_title：AIDS research and therapy

authors： Pomerantz HS,Xu X,White J,Sunil TS,Deiss RG,Ganesan A,Agan BK,Okulicz JF

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:HIV spread continues at high rates from infected persons to their sexual partners. In 2009, an estimated 2.6 million new infections occurred globally. People living with HIV (PLHIV) receiving treatment are in contact with health workers and therefore exposed to prevention messages. By contrast, PLHIV not rec...

journal_title：AIDS research and therapy

authors： Sarna A,Luchters S,Pickett M,Chersich M,Okal J,Geibel S,Kingola N,Temmerman M

更新日期：2012-03-19 00:00:00

abstract：BACKGROUND:Minocycline is a tetracycline antibiotic that has been shown to attenuate central nervous system (CNS) lentivirus infection, immune activation, and brain injury in model systems. To initiate assessment of minocycline as an adjuvant therapy in human CNS HIV infection, we conducted an open-labelled pilot study...

journal_title：AIDS research and therapy

authors： Ho EL,Spudich SS,Lee E,Fuchs D,Sinclair E,Price RW

更新日期：2011-05-12 00:00:00

abstract：:HIV-1 can persist in a latent form in resting memory CD4+ cells and macrophages carrying an integrated copy of the HIV genome. Because of the presence of these stable reservoir cells, eradication by antiretroviral therapy is unlikely and in order to achieve eradication, alternative treatment options are required. Stem...

journal_title：AIDS research and therapy

authors： Hütter G

更新日期：2016-09-13 00:00:00

abstract：OBJECTIVE:Recent studies have shown that the current guidelines suggesting immunologic monitoring to determine response to highly active antiretroviral therapy (HAART) are inadequate. We assessed whether routinely collected clinical markers could improve prediction of concurrent HIV RNA levels. METHODS:We included ind...

journal_title：AIDS research and therapy

authors： Lau B,Chander G,Gange SJ,Moore RD

更新日期：2010-07-23 00:00:00

abstract：BACKGROUND:Although the introduction of combined therapy with reverse transcriptase and protease inhibitors has resulted in considerable decrease in HIV related mortality; it has also induced the development of multiple drug-resistant HIV-1 variants. The few studies on HIV-1 mutagenesis in HIV infected children have no...

journal_title：AIDS research and therapy

authors： Malhotra A,Gaur S,Whitley-Williams P,Loomis C,Petrova A

更新日期：2007-07-09 00:00:00

abstract：:Bone health status is largely absent in South Africa, the main reasons being the absence and cost-effectiveness of specific screening equipment for assessing bone mineral density (BMD). Various risk factors seem to play a role, some of which can be modified to change bone health status. Urbanisation is also a public h...

journal_title：AIDS research and therapy

authors： Kruger MJ,Nell TA

更新日期：2017-07-26 00:00:00

abstract：: In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred during a phase of uncontrolled viral replication combined with a severe immunodeficiency and resolved by an effect...

journal_title：AIDS research and therapy

authors： Esposito A,Conti V,Cagliuso M,Pastori D,Fantauzzi A,Mezzaroma I

更新日期：2011-03-01 00:00:00

abstract：UNLABELLED: OBJECTIVE:To investigate anti-infective treatments in HIV-infected surgical patients during the perioperative period. METHODS:A retrospective study of sepsis and surgical site infections (SSIs) was conducted in 266 HIV-infected patients. The patients were divided into 3 groups based on CD4+ T cells counts...

journal_title：AIDS research and therapy

authors： Liu B,Zhang L,Guo R,Su J,Li L,Si Y

更新日期：2012-11-27 00:00:00

abstract：BACKGROUND:Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African populations, but data on their influence on plasma nevirapine concentration and clinical response in African women are limited. We investigated the impact o...

journal_title：AIDS research and therapy

authors： Oluka MN,Okalebo FA,Guantai AN,McClelland RS,Graham SM

更新日期：2015-04-15 00:00:00

abstract：BACKGROUND:Reports on the sexual behavior of people on antiretroviral therapy (ART) are inconsistent. We selected 14 articles that compared the sexual behavior of people with and without ART for this analysis. METHODS:We included both cross-sectional studies that compared different ART-naïve and ART-experienced partic...

journal_title：AIDS research and therapy

authors： Berhan A,Berhan Y

更新日期：2012-05-14 00:00:00

abstract：: After the introduction of highly active antiretroviral therapies (HAART), an increased incidence of insulin resistance, diabetes mellitus (DM), and cardiovascular diseases has been described. The impact of such conditions on mortality in the post-HAART era has been also assessed in various modes in the literature. In...

journal_title：AIDS research and therapy

authors： Serraino D,Bruzzone S,Zucchetto A,Suligoi B,De Paoli A,Pennazza S,Camoni L,Dal Maso L,De Paoli P,Rezza G

更新日期：2010-05-24 00:00:00

abstract：BACKGROUND:Antiretroviral therapy (ART) has modified the natural history of HIV-infection: the incidence of opportunistic infections (OIs) has decreased and mortality associated to HIV has improved dramatically. The reasons for hospitalization have changed; OIs are no longer the most common reason for admission. This s...

journal_title：AIDS research and therapy

authors： Álvarez Barreneche MF,Restrepo Castro CA,Hidrón Botero A,Villa Franco JP,Trompa Romero IM,Restrepo Carvajal L,Eusse García A,Ocampo Mesa A,Echeverri Toro LM,Porras Fernández de Castro GP,Ramírez Rivera JM,Agudelo Restrepo CA

更新日期：2017-11-13 00:00:00

abstract：:Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary. ...

journal_title：AIDS research and therapy

authors： Slobod KS,Coleclough C,Brown SA,Stambas J,Zhan X,Surman S,Jones BG,Zirkel A,Freiden PJ,Brown B,Sealy R,Bonsignori M,Hurwitz JL

更新日期：2005-04-28 00:00:00

abstract：BACKGROUND:Practical screening strategies are necessary to detect neurocognitive impairment of all severities in HIV populations, which remains prevalent despite highly active antiretroviral therapy and requires full neuropsychological testing for diagnosis. We aimed to develop a brief and clinically feasible battery t...

journal_title：AIDS research and therapy

authors： Chan LG,Ho MJ,Lin YC,Ong Y,Wong CS

更新日期：2019-04-15 00:00:00

abstract：INTRODUCTION:We report a case of an adult patient with human immunodeficiency virus (HIV), acute respiratory distress syndrome (ARDS) and ventilator associated pneumonia (VAP) caused by multidrug resistant (MDR) bacteria that was successfully managed with veno-venous extracorporeal membrane oxygenation (ECMO). CASE RE...

journal_title：AIDS research and therapy

authors： Samalavicius R,Serpytis M,Ringaitiene D,Grazulyte D,Bertasiute R,Rimkus B,Matulionyte R,Ambrazaitiene R,Sipylaite J,Kacergius T,Griskevicius L

更新日期：2014-11-21 00:00:00

abstract：BACKGROUND:About 13 years since the introduction of antiretroviral therapy (ART) for children living with HIV (CLHIV) in Zambia, HIV/AIDS testing and treatment guidelines for children have evolved over the years with limited documentation of long-term trends in the numbers testing HIV positive and initiating ART. We ex...

journal_title：AIDS research and therapy

authors： Munthali T,Michelo C,Mee P,Moyo C,Kashoka A,Liswaniso L,Chiboma I,Todd J

更新日期：2020-05-14 00:00:00

abstract：BACKGROUND:Hypogonadism is common among HIV-infected men, even among men receiving antiretroviral therapy (ART). Our objective in this study was to determine the prevalence of biochemical hypogonadism among HIV-infected men compared with HIV-uninfected controls. We also examined the use of free testosterone (FT) and to...

journal_title：AIDS research and therapy

authors： Monroe AK,Dobs AS,Palella FJ,Kingsley LA,Witt MD,Brown TT

更新日期：2014-01-22 00:00:00

abstract：:Intracellular levels of glutathione are depleted in patients with acquired immunodeficiency syndrome in whom the risk of tuberculosis, particularly disseminated disease is many times that of healthy individuals. In this study, we examined the role of glutathione in immunity against tuberculosis infection in samples de...

journal_title：AIDS research and therapy

authors： Venketaraman V,Rodgers T,Linares R,Reilly N,Swaminathan S,Hom D,Millman AC,Wallis R,Connell ND

更新日期：2006-02-20 00:00:00

abstract：BACKGROUND:Antiretroviral therapy (ART) use by people living with HIV reduces HIV transmission, morbidity, mortality, and improves quality of life. Good ART adherence is required to achieve these benefits. We investigated how the environmental, social, economic and behavioural experiences of people living with HIV with...

journal_title：AIDS research and therapy

authors： Bukenya D,Mayanja BN,Nakamanya S,Muhumuza R,Seeley J

更新日期：2019-01-21 00:00:00

abstract：BACKGROUND:Tubular dysfunction is common in HIV-infected people and detection of proteinuria is essential to identify this problem. In low-income countries, resources for detection of proteinuria using the Kidney Disease Improve Global Outcomes (KDIGO) gold standard urinary protein/creatinine ratio (uPCR) is rarely pos...

journal_title：AIDS research and therapy

authors： López De León JI,Mata-Marín JA,Andrade-Fuentes K,Huerta-Garcia G,Domínguez-Hemosillo JC,Gaytán-Martínez J

更新日期：2015-03-21 00:00:00

abstract：BACKGROUND:In many countries in Asia, the HIV epidemic is in a concentrated phase, with high prevalence in certain risk groups, such as men who inject drugs. There is also a rapid increase of HIV among women. The latter might be due to high levels of sero-discordant couples and increasing transmission from male to fema...

journal_title：AIDS research and therapy

authors： Van Tam V,Cuong DD,Alfven T,Phuc HD,Chuc NT,Hoa NP,Diwan V,Larsson M

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Identifying those at increased risk of death during TB treatment is a priority in resource-constrained settings. We performed this study to determine predictors of mortality during TB treatment. METHODS:We performed a retrospective analysis of a TB surveillance population in a high HIV prevalence area that ...

journal_title：AIDS research and therapy

authors： Pepper DJ,Schomaker M,Wilkinson RJ,de Azevedo V,Maartens G

更新日期：2015-10-06 00:00:00

abstract：:A segment of the HIV infected population develops abnormal and excessive accumulation of adipose tissue in the trunk, including accumulation of visceral (deep abdominal) adipose tissue. This condition, known as HIV-related adipose redistribution syndrome (HARS), may also be accompanied by fat accumulation in the upper...

journal_title：AIDS research and therapy

authors： Lichtenstein K,Balasubramanyam A,Sekhar R,Freedland E

更新日期：2007-07-16 00:00:00

abstract：:HIV-1 infects gut associated lymphoid tissues (GALT) very early after transmission by multiple routes. The infected GALT consequently serves as the major reservoir for HIV-1 infection and could constantly shed HIV-1 and CD4+ T cells into the intestinal lumen. To examine this hypothesis, we monitored HIV-1 RNA/DNA and ...

journal_title：AIDS research and therapy

authors： Chakrabarti AK,Caruso L,Ding M,Shen C,Buchanan W,Gupta P,Rinaldo CR,Chen Y

更新日期：2009-10-02 00:00:00