Stratification of patients with unclassified pain in the FabryScan database.

abstract：Purpose:Gabapentinoids are currently the mainstay of pharmacological treatments for patients with neuropathic pain. Little is known about the effects of this therapy on the integrity of neuronal networks, especially in patients with an already-damaged nervous system. Since gabapentinoids can worsen cognitive functions ...

journal_title：Journal of pain research

authors： Baldewig M,Goldbaum O,Richter-Landsberg C,Weyland A,Bantel C

更新日期：2018-06-20 00:00:00

abstract：:Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery. Recent expe...

journal_title：Journal of pain research

authors： Bottros MM,Christo PJ

更新日期：2014-11-06 00:00:00

abstract：Background:It has been reported that N-cadherin and cAMP response element binding protein (CREB) in the spinal cord are critical for synaptogenesis and regulation of excitatory synapse function, which could underlie chronic pain development. The aim of the present study was to investigate the role of spinal N-cadherin/...

journal_title：Journal of pain research

authors： Ma Y,Zhang X,Li C,Liu S,Xing Y,Tao F

更新日期：2020-08-12 00:00:00

abstract：Background:Acupotomy, which involves the addition of a scalpel function to the conventional acupuncture treatment, has recently been applied as a conservative treatment method for lumbar disc herniation (LDH). This study investigated the effectiveness and safety of acupotomy, compared to manual acupuncture, for the tre...

journal_title：Journal of pain research

authors： Jeong JK,Kim E,Yoon KS,Jeon JH,Kim YI,Lee H,Kwon O,Jung SY,Lee JH,Yang C,Kang JH,Han CH

更新日期：2020-04-01 00:00:00

abstract：:Objectives: To classify patients suffering from low back pain (LBP) into two different groups - patients with lumbar disc herniation (LDH) and patients without this disease based on simple questions and without magnetic resonance imaging (MRI) procedure - and to diagnose the most effective risk factors of LDH. Methods...

journal_title：Journal of pain research

authors： Jafari S,Dehesh T,Iranmanesh F

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Large interindividual differences in clinical responses to opioids and the variable susceptibility to abuse of this class of drugs make their use problematic. We lack a full understanding of the factors responsible for these differences. Dietary factors including methyl donor content have been noted to alter...

journal_title：Journal of pain research

authors： Liang DY,Sun Y,Clark JD

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Low back pain is often called nonspecific pain. In this type of low back pain, various emotions and stress are known to strongly affect pain perception. The purpose of this study is to investigate how the degree of low back pain changes in people with chronic mild low back pain when they are inside and outsi...

journal_title：Journal of pain research

authors： Sakakibara T,Wang Z,Kasai Y

更新日期：2012-01-01 00:00:00

abstract：:Purpose: Thirty percent of patients with postherpetic neuralgia (PHN) receiving conservative treatment report unsatisfactory pain relief. Epidural steroid injections (ESIs) are commonly used as a therapeutic intervention in these patients. In this study, we aimed to determine if there are variables that predict the ef...

journal_title：Journal of pain research

authors： Ghanavatian S,Wie CS,Low RS,Butterfield RJ,Zhang N,Dhaliwal GS,Montoya JM,Swanson DL

更新日期：2019-04-23 00:00:00

abstract：INTRODUCTION:Frequent chronic local pain can develop into chronic widespread pain (CWP). The spread of pain is correlated with pain intensity, anxiety, and depression, conditions that ultimately lead to a poor quality of life. Knowledge is incomplete about CWP's etiology, although it has been suggested that both centra...

journal_title：Journal of pain research

authors： Olausson P,Ghafouri B,Bäckryd E,Gerdle B

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. METHODS:This prospective, observational study evaluated changes from bas...

journal_title：Journal of pain research

authors： Gudin JA,Brennan MJ,Harris ED,Hurwitz PL,Dietze DT,Strader JD

更新日期：2017-10-03 00:00:00

abstract：:The objective of this study was to evaluate the relationship between magnetic resonance imaging (MRI) findings and previous low back pain (LBP) in participants without current LBP. Current LBP was defined as LBP during the past month. Previous LBP was defined as a history of medical consultation for LBP. Ninety-one pa...

journal_title：Journal of pain research

authors： Tonosu J,Oka H,Matsudaira K,Higashikawa A,Okazaki H,Tanaka S

更新日期：2016-12-29 00:00:00

abstract：Background:Thoracoscopic surgery (TS) has been performed as a minimally invasive procedure since the beginning of the 1990s. This has led to a dramatic change in the postoperative condition of these patients, facilitating early ambulation and easier management of postoperative pain. However, empirical evidence on posto...

journal_title：Journal of pain research

authors： Kuroda H,Mizuno H,Dejima H,Watanabe K,Yoshida T,Naito Y,Sakao Y

更新日期：2017-11-15 00:00:00

abstract：Objectives:Pain is reported as one of the most common and burdensome symptoms for children with cancer. Pain catastrophizing is clearly related to pain intensity and disability. Catastrophizing in parents is associated with both child functioning and parent distress. The Pain Catastrophizing Scale for Parents (PCS-P) r...

journal_title：Journal of pain research

authors： Cederberg JT,Weineland S,Dahl J,Ljungman G

更新日期：2019-03-18 00:00:00

abstract：:Diabetic peripheral neuropathy (DPN) represents significant burdens to many patients and the public health-care system. Patients with diabetes in rural areas have higher risk of developing complications and having less access to proper treatment. We studied a rural population of patients with diabetes who attended a p...

journal_title：Journal of pain research

authors： Pruitt J 3rd,Moracho-Vilrriales C,Threatt T,Wagner S,Wu J,Romero-Sandoval EA

更新日期：2017-04-07 00:00:00

abstract：:Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 yea...

journal_title：Journal of pain research

authors： Sofat N,Harrison A,Russell MD,Ayis S,Kiely PD,Baker EH,Barrick TR,Howe FA

更新日期：2017-10-10 00:00:00

abstract：:Duloxetine is a serotonin-norepinephrine reuptake inhibitor approved by the US Food and Drug Administration for the treatment of fibromyalgia and painful diabetic neuropathy at doses of 60 mg daily. Duloxetine has been shown to significantly improve the symptoms of chronic pain associated with these disorders, as meas...

journal_title：Journal of pain research

authors： Wright A,Luedtke KE,Vandenberg C

更新日期：2010-12-16 00:00:00

abstract：:Paced breathing has shown efficacy in fibromyalgia (FM), but the mechanisms associated with symptom change are largely unknown. We investigated whether changes in respiratory rate (RR) alone resulted in autonomic changes during normal, paced, and mechanically assisted breathing in untrained FM patients and controls. P...

journal_title：Journal of pain research

authors： Schmidt JE,O'Brien TG,Hooten WM,Joyner MJ,Johnson BD

更新日期：2017-12-08 00:00:00

abstract：Background:The objective of this study was to compare the efficacy of calcitonin with diclofenac sodium in the treatment of patients with nonspecific low back pain (LBP) and type I Modic changes (MC1). Patients and methods:The study was a retrospective observational study with 109 patients who had nonspecific LBP and ...

journal_title：Journal of pain research

authors： Zhou J,Li T,Li L,Xue Y

更新日期：2018-07-17 00:00:00

abstract：:Purpose: Although amiodarone is classified as a Vaughan-Williams class Ⅲ antiarrhythmic drug, it has inhibitory effects on voltage-gated sodium and calcium channels and on β-adrenergic receptors. Given these pharmacological profiles, amiodarone may have analgesic properties. Most patients who are prescribed amiodarone...

journal_title：Journal of pain research

authors： Kotoda M,Ino H,Kumakura Y,Iijima T,Ishiyama T,Matsukawa T

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:Even though pain is a subjective phenomenon, its objective evaluation in humans is important because subjects requiring pain evaluation may be unable to describe their pain intensity because of decreased awareness or impaired cognitive function. Previous reports indicate that the perfusion index (PI), which ...

journal_title：Journal of pain research

authors： Nishimura T,Nakae A,Shibata M,Mashimo T,Fujino Y

更新日期：2014-02-10 00:00:00

abstract：:Rotator-cuff tears (RCTs) are typically associated with chronic pain. The most common treatment for reducing pain is the injection of cortisone into the injury site. An alternative and increasingly used technique is the injection of autologous platelet-rich plasma (PRP). A limitation of cortisone is its pain relief is...

journal_title：Journal of pain research

authors： Kuffler DP

更新日期：2018-10-09 00:00:00

abstract：BACKGROUND:It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing of nociceptors. The p...

journal_title：Journal of pain research

authors： Nakagawa H,Hiura A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Previous studies have already reported an independent effect of light-load eccentric exercise (10% eccentric exercise contraction [EEC]) and low-level laser therapy (LLLT) as a protective measure against more strenuous eccentric exercise. However, the difference between these two interventions is l...

journal_title：Journal of pain research

authors： Nausheen S,Moiz JA,Raza S,Shareef MY,Anwer S,Alghadir AH

更新日期：2017-09-11 00:00:00

abstract：:Temporal sensory summation of pain (TSSP) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. Aftersensations (ASs) are pain sensations that remain after TSSP has been induced. We examined the within-session and across-session variabil...

journal_title：Journal of pain research

authors： Alappattu MJ,Bishop MD,Bialosky JE,George SZ,Robinson ME

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:This paper aimed to investigate motor proficiency in fine and gross motor function, with a focus on reaction time (RT) and movement skill, in patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS) compared to healthy controls (HC). METHODS:A total of 60 individuals (20 CFS, 20 FM, and 20 HC), age 1...

journal_title：Journal of pain research

authors： Rasouli O,Fors EA,Borchgrevink PC,Öhberg F,Stensdotter AK

更新日期：2017-02-07 00:00:00

abstract：BACKGROUND:Detecting the efficacy of novel analgesic agents in neuropathic pain is challenging. There is a critical need for study designs with the desirable characteristics of assay sensitivity, low placebo response, reliable pain recordings, low cost, short duration of exposure to test drug and placebo, and relevant ...

journal_title：Journal of pain research

authors： Jenkins TM,Smart TS,Hackman F,Cooke C,Tan KK

更新日期：2012-01-01 00:00:00

abstract：Background:It is becoming increasingly important to understand the mechanisms of spinal cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise. Purpose:Additionally, the small anatomic scale of current SCS animal models is a barrier to more translational research. Methods:Using ch...

journal_title：Journal of pain research

authors： Reddy CG,Miller JW,Abode-Iyamah KO,Safayi S,Wilson S,Dalm BD,Fredericks DC,Gillies GT,Howard MA 3rd,Brennan TJ

更新日期：2018-06-15 00:00:00

abstract：:Pain is highly prevalent, but frequently untreated or under-treated, and health care professionals are faced with a range of treatment challenges. Multimodal therapy is recommended and can be achieved using open combinations (ie, concomitant administration) of individual agents, fixed-dose combinations (FDCs), or mult...

journal_title：Journal of pain research

authors： Almansa C,Frampton CS,Vela JM,Whitelock S,Plata-Salamán CR

更新日期：2019-09-04 00:00:00

abstract：:Generalized joint hypermobility (GJH) is highly prevalent among patients diagnosed with chronic pain. When GJH is accompanied by pain in ≥4 joints over a period ≥3 months in the absence of other conditions that cause chronic pain, the hypermobility syndrome (HMS) may be diagnosed. In addition, GJH is also a clinical s...

journal_title：Journal of pain research

authors： Scheper MC,de Vries JE,Verbunt J,Engelbert RH

更新日期：2015-08-20 00:00:00

abstract：Background:This study evaluates the reporting quality of randomized controlled trials (RCTs) on acupuncture use for the treatment of postherpetic neuralgia and explores related factors. Methods:The following six databases PubMed, Embase, Cochrane Library, VIP, CNKI, and SinoMed, were systematically searched from their...

journal_title：Journal of pain research

authors： Liu K,Zeng J,Pei W,Chen S,Luo Z,Lu L,Lin G

更新日期：2019-07-29 00:00:00