Abstract：
:Objectives: To classify patients suffering from low back pain (LBP) into two different groups - patients with lumbar disc herniation (LDH) and patients without this disease based on simple questions and without magnetic resonance imaging (MRI) procedure - and to diagnose the most effective risk factors of LDH. Methods: Four hundred patients aged over 18 years suffering from LBP for over 6 months were randomized into two groups in this cross-sectional study. The data were gathered at Besat clinic, in Kerman, southeast of Iran. Twelve dichotomous questions from the main LDH risk factors were asked. Three statistical classification methods - K-nearest neighbors (KNN), support vector machine (SVM), and logistic regression (LR) - were performed. LR was used in order to diagnose the most important risk factors of LDH. Results: SVM method was more efficient among the small sample sizes, while KNN method showed the best classification relative to other methods when the sample size increased. LR model had the least efficiency of all. The drug use increased the chance of LDH more than 7 times (OR=7.249), and the chance of having LDH among people who had associated illness was 4.847 times more compared with people who did not have. Using hookah increased the chance of having LDH more than twice (OR=2.401), and the chance of smokers for LDH was near four times higher than nonsmokers (OR=3.877). Conclusion: The statistical classification methods had acceptable precisions for diagnosis of LDH patients. It is suggested that neurologists become more familiar with these methods and use them before MRI prescription to decrease the unnecessary burden on health services. Addiction to drugs, cigarettes, and hookah is the main factor in the creation of a lumbar disc herniation.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
Jafari S,Dehesh T,Iranmanesh Fdoi
10.2147/JPR.S189927subject
Has Abstractpub_date
2019-04-15 00:00:00pages
1179-1187issn
1178-7090pii
189927journal_volume
12pub_type
杂志文章abstract：OBJECTIVES:Effective postoperative pain management is crucial in the care of surgical patients. Opioids, which are commonly used in managing postoperative pain, have a potential for tolerance and addiction, along with sedating side effects. Gabapentin's use as a multimodal analgesic regimen to treat neuropathic pain ha...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S112626
更新日期：2016-09-12 00:00:00
abstract：:The observation of pain in others may enhance or reduce self-pain, yet the boundary conditions and factors that determine the direction of such effects are poorly understood. The current study set out to show that visual stimulus awareness plays a crucial role in determining whether vicarious pain primarily activates ...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S132744
更新日期：2017-07-31 00:00:00
abstract：BACKGROUND:One form of self-medication is sharing of medications, defined as borrowing or lending medications in situations where the receiver of these drugs is not the individual to whom the medications were allocated. OBJECTIVE:To explore experiences and opinions of patients about sharing prescription analgesics, re...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S123554
更新日期：2017-02-10 00:00:00
abstract：Objective:To demonstrate the importance of recognizing and separating nonmedian nerve-related symptoms from those related to median nerve compression at the carpal tunnel. Methods:The records of 80 patients, aged 31-82 years (39 males and 41 females), who had undergone median nerve decompression using open and endosco...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S142153
更新日期：2017-10-24 00:00:00
abstract：Objective:To examine the influence of anxiety and pain-related catastrophizing on the time course of acute interleukin-6 (IL-6) responses to standardized noxious stimulation among patients with chronic pain. Methods:Data were collected from 48 participants in the following demographically matched groups: patients with...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S147735
更新日期：2018-03-28 00:00:00
abstract：PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S65607
更新日期：2014-11-26 00:00:00
abstract：OBJECTIVE:Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH)...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S118105
更新日期：2017-01-13 00:00:00
abstract：:A 41-year-old woman presented with burning and erythema in her extremities triggered by warmth and activity, which was relieved by applying ice. Extensive workup was consistent with adult-onset primary erythromelalgia (EM). Several pharmacological treatments were tried including local anesthetics, capsaicin, ziconotid...
journal_title：Journal of pain research
pub_type：
doi：10.2147/JPR.S129661
更新日期：2017-04-27 00:00:00
abstract：BACKGROUND:While studies have demonstrated the economic burden of migraines in terms of quality of life, health care resource use (HRU), and costs, there exists a notable paucity of data comparing such outcomes among migraineurs with nausea and vomiting (N/V) and those without. The current study aimed to address this g...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S124683
更新日期：2017-03-24 00:00:00
abstract：Purpose:Pregabalin is indicated for postherpetic neuralgia (PHN) in multiple countries, including China. This analysis compared pregabalin efficacy and safety in Chinese and international patients with PHN. Patients and methods:Data from Chinese and international randomized, double-blind, placebo-controlled trials wer...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S157856
更新日期：2018-09-03 00:00:00
abstract：BACKGROUND:It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing of nociceptors. The p...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S41614
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a serious medical and socioeconomic problem in recent decades. Patients suffering from chronic pain seem to have a higher prevalence of sleep disorders. PURPOSE:To calculate the prevalence of sleep deprivation in patients with CLBP and CNP...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S36386
更新日期：2013-01-01 00:00:00
abstract：Background:This study evaluates the reporting quality of randomized controlled trials (RCTs) on acupuncture use for the treatment of postherpetic neuralgia and explores related factors. Methods:The following six databases PubMed, Embase, Cochrane Library, VIP, CNKI, and SinoMed, were systematically searched from their...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S210471
更新日期：2019-07-29 00:00:00
abstract：OBJECTIVE:Chronic pelvic pain (CPP) is widely acknowledged as a common problem with significant consequences for those diagnosed with this condition. There is a lack of studies with good sample size that provide a comprehensive psychological profile of women presenting to specialist chronic pain clinics. Therefore, the...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S115065
更新日期：2016-11-16 00:00:00
abstract：Background:The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF). Materials and methods:The records ...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S172953
更新日期：2018-10-26 00:00:00
abstract：Objectives:Estimate the prevalence of neuropathic pain (NeP) among chronic pain patients attending Brazilian hospitals and pain clinics in São Paulo, Ceara, and Bahia and explore clinical characteristics by subtypes: painful diabetic peripheral neuropathy (pDPN), central neuropathic pain (CNP), chronic low back pain wi...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S160504
更新日期：2019-01-07 00:00:00
abstract：UNLABELLED:Postsurgical pain management remains a significant challenge. Liposome bupivacaine, as part of a multimodal analgesic regimen, has been shown to significantly reduce postsurgical opioid consumption, hospital length of stay (LOS), and hospitalization costs in gastrointestinal (GI) surgery, compared with intra...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S63764
更新日期：2014-06-24 00:00:00
abstract：:This paper reviews the current clinical data for the role of transdermal buprenorphine (BUP TDS) in the treatment of diverse acute and chronic pain syndromes. Literature searches were carried out using PubMed (1988 to June 2009). The published findings seem to support hypotheses regarding the rather unique analgesic m...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/jpr.s6503
更新日期：2009-09-15 00:00:00
abstract：:Patients with chronic non-malignant pain report impairments of physical, social, and psychological well-being. The goal of pain management should include reducing pain and improving quality of life. Patients with chronic pain require medications that are able to provide adequate pain relief, have minimum dosing interv...
journal_title：Journal of pain research
pub_type： 杂志文章,评审
doi：10.2147/JPR.S49502
更新日期：2014-03-24 00:00:00
abstract：Background:The objective of this study was to compare the efficacy of calcitonin with diclofenac sodium in the treatment of patients with nonspecific low back pain (LBP) and type I Modic changes (MC1). Patients and methods:The study was a retrospective observational study with 109 patients who had nonspecific LBP and ...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S158718
更新日期：2018-07-17 00:00:00
abstract：BACKGROUND:Large interindividual differences in clinical responses to opioids and the variable susceptibility to abuse of this class of drugs make their use problematic. We lack a full understanding of the factors responsible for these differences. Dietary factors including methyl donor content have been noted to alter...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S42561
更新日期：2013-01-01 00:00:00
abstract：INTRODUCTION:Frequent chronic local pain can develop into chronic widespread pain (CWP). The spread of pain is correlated with pain intensity, anxiety, and depression, conditions that ultimately lead to a poor quality of life. Knowledge is incomplete about CWP's etiology, although it has been suggested that both centra...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S125667
更新日期：2017-03-13 00:00:00
abstract：BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S15380
更新日期：2011-03-07 00:00:00
abstract：Background:G protein-gated inwardly rectifying potassium (GIRK) channels are involved in the regulation of neuronal excitability. Four GIRK subunits (GIRK1-4) are expressed in rat dorsal root ganglia (DRGs). Recently, we have characterized the expression of GIRK1 and -2, and both are downregulated in rat DRGs and spina...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S233744
更新日期：2020-02-17 00:00:00
abstract：Objectives:Pain is reported as one of the most common and burdensome symptoms for children with cancer. Pain catastrophizing is clearly related to pain intensity and disability. Catastrophizing in parents is associated with both child functioning and parent distress. The Pain Catastrophizing Scale for Parents (PCS-P) r...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S193164
更新日期：2019-03-18 00:00:00
abstract：Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S164939
更新日期：2018-09-13 00:00:00
abstract：Purpose:The aim of this study was to evaluate postoperative discomfort in patients undergoing ambulatory strabismus under general anesthesia, and to identify risk factors associated with the discomfort. Patients and Methods:A cross-sectional study was conducted among 210 consecutive patients undergoing ambulatory stra...
journal_title：Journal of pain research
pub_type：
doi：10.2147/JPR.S249493
更新日期：2020-05-05 00:00:00
abstract：:Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/jpr.s10025
更新日期：2010-05-17 00:00:00
abstract：OBJECTIVE:Patient controlled analgesia (PCA) is commonly used to provide analgesia following surgical procedures in the pediatric population. Morphine and hydromorphone remain the most commonly used opioids for PCA. Although both are effective, adverse effects may occur. When these adverse effects are unremitting or se...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S64497
更新日期：2014-08-13 00:00:00
abstract：Objective:Chronic pain is a highly prevalent and costly condition with few proven treatment options. Since 2014, Geisinger's Department of Pain Medicine has implemented the Multidisciplinary Pain Program (MPP), which consists of a 3-day educational seminar followed by 12 months of comprehensive care. This study examine...
journal_title：Journal of pain research
pub_type： 杂志文章
doi：10.2147/JPR.S177231
更新日期：2018-10-18 00:00:00
