Dietary methyl content regulates opioid responses in mice.

abstract：Background:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis patients often present with psychiatric symptoms, cognitive dysfunction, epilepsy and memory deficits. A previous study has suggested that headache can occurr during the early stages of anti-NMDAR encephalitis. However, the exact association between hea...

journal_title：Journal of pain research

authors： Ma C,Wang C,Zhang Q,Lian Y

更新日期：2019-01-30 00:00:00

abstract：Purpose:The aim of this prospective study was to assess the behavior of emergency department (ED) nurses with regard to pain and their role in pain management in a real-life clinical setting. Methods:A total of 509 consecutive patients were enrolled during a 6-week period. A case-report form was used to collect data o...

journal_title：Journal of pain research

authors： Sardo S,Galletta M,Coni E,Aviles Gonzalez CI,Piras I,Pia G,Evangelista M,Musu M,Finco G

更新日期：2020-09-22 00:00:00

abstract：:Cancer and cancer treatment-related chronic pain affect a significant number of patients. The etiology of this pain is diverse and may include nociceptive and/or neuropathic characteristics. Treatment is often multifactorial and may require advanced interventional techniques, such as spinal cord stimulation (SCS). Thi...

journal_title：Journal of pain research

authors： Hagedorn JM,Pittelkow TP,Hunt CL,D'Souza RS,Lamer TJ

更新日期：2020-12-07 00:00:00

abstract：Background:Neuroplastic changes in nociceptive pathways contribute to severity of symptoms in knee osteoarthritis (KOA). A new look at neuroplastic changes management includes modulation of the primary motor cortex by transcranial direct current stimulation (tDCS). Objectives:We investigated whether tDCS combined with...

journal_title：Journal of pain research

authors： da Graca-Tarragó M,Lech M,Angoleri LDM,Santos DS,Deitos A,Brietzke AP,Torres IL,Fregni F,Caumo W

更新日期：2019-01-03 00:00:00

abstract：Background:Regional variations of opioid use have been reported from many countries. The objective of this study was to examine opioid prescribing patterns in Germany including low- and high-potency opioids (LPO and HPO) focusing on regional differences. Methods:Data source was the "Information system for health care ...

journal_title：Journal of pain research

authors： Jobski K,Dörks M,Bantel C,Hoffmann F

更新日期：2020-10-07 00:00:00

abstract：Objective:To report a rare case of spontaneous fusion (SF) following cervical disc arthroplasty (CDA), to review the related literature, and to propose a new measure to prevent it. Methods:The course of a patient with SF is described here. The potential causes, risk factors, and preventive measure of SF after CDA publ...

journal_title：Journal of pain research

authors： Ge CY,Wang J,Zhang BF,Hui H,Shan LQ,Zhao QP,Hao DJ

更新日期：2020-04-21 00:00:00

abstract：PURPOSE:This paper aimed to investigate motor proficiency in fine and gross motor function, with a focus on reaction time (RT) and movement skill, in patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS) compared to healthy controls (HC). METHODS:A total of 60 individuals (20 CFS, 20 FM, and 20 HC), age 1...

journal_title：Journal of pain research

authors： Rasouli O,Fors EA,Borchgrevink PC,Öhberg F,Stensdotter AK

更新日期：2017-02-07 00:00:00

abstract：BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...

journal_title：Journal of pain research

authors： Lionberger DR,Joussellin E,Lanzarotti A,Yanchick J,Magelli M

更新日期：2011-03-07 00:00:00

abstract：:Rotator-cuff tears (RCTs) are typically associated with chronic pain. The most common treatment for reducing pain is the injection of cortisone into the injury site. An alternative and increasingly used technique is the injection of autologous platelet-rich plasma (PRP). A limitation of cortisone is its pain relief is...

journal_title：Journal of pain research

authors： Kuffler DP

更新日期：2018-10-09 00:00:00

abstract：OBJECTIVE:This systematic review aimed to assess the efficacy, effectiveness, safety, and tolerability of osteopathic manipulative treatment (OMT) in patients with headache. BACKGROUND:Migraine is one of the most common and disabling medical conditions. It affects more than 15% of the general population, causing high ...

journal_title：Journal of pain research

authors： Cerritelli F,Lacorte E,Ruffini N,Vanacore N

更新日期：2017-03-14 00:00:00

abstract：OBJECTIVE:Patients with chronic fatigue syndrome (CFS) complain of long-lasting fatigue and pain which are not relieved by rest and worsened by physical exertion. Previous research has implicated metaboreceptors of muscles to play an important role for chronic fatigue and pain. Therefore, we hypothesized that blocking ...

journal_title：Journal of pain research

authors： Staud R,Kizer T,Robinson ME

更新日期：2017-06-26 00:00:00

abstract：OBJECTIVE:Patient controlled analgesia (PCA) is commonly used to provide analgesia following surgical procedures in the pediatric population. Morphine and hydromorphone remain the most commonly used opioids for PCA. Although both are effective, adverse effects may occur. When these adverse effects are unremitting or se...

journal_title：Journal of pain research

authors： DiGiusto M,Bhalla T,Martin D,Foerschler D,Jones MJ,Tobias JD

更新日期：2014-08-13 00:00:00

abstract：BACKGROUND:Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, t...

journal_title：Journal of pain research

authors： Fanelli G,De Carolis G,Leonardi C,Longobardi A,Sarli E,Allegri M,Schatman ME

更新日期：2017-05-22 00:00:00

abstract：Background:Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by a subset of nociceptive neurons that acts as a multimodal receptor. Its activity contributes to modulate nociceptive transmission in acute inflammatory pain. However, the role of this channel in chronic pain has bee...

journal_title：Journal of pain research

authors： Martínez-Rojas VA,García G,Noriega-Navarro R,Guzmán-Priego CG,Torres-López JE,Granados-Soto V,Murbartián J

更新日期：2017-12-27 00:00:00

abstract：Purpose:Gabapentinoids are currently the mainstay of pharmacological treatments for patients with neuropathic pain. Little is known about the effects of this therapy on the integrity of neuronal networks, especially in patients with an already-damaged nervous system. Since gabapentinoids can worsen cognitive functions ...

journal_title：Journal of pain research

authors： Baldewig M,Goldbaum O,Richter-Landsberg C,Weyland A,Bantel C

更新日期：2018-06-20 00:00:00

abstract：BACKGROUND:Diagnosis of fibromyalgia (FM), a chronic musculoskeletal condition characterized by widespread pain and a constellation of symptoms, remains challenging and is often delayed. METHODS:Random forest modeling of electronic medical records was used to identify variables that may facilitate earlier FM identific...

journal_title：Journal of pain research

authors： Emir B,Masters ET,Mardekian J,Clair A,Kuhn M,Silverman SL

更新日期：2015-06-10 00:00:00

abstract：Purpose:The study aimed at the evaluation of the impact of intravenous (IV) dexamethasone on efficacy and duration of analgesia of paravertebral block (PVB) in patients undergoing modified radical mastectomy (MRM). Patients and methods:This randomized, double-blind controlled trial included 50 patients with breast can...

journal_title：Journal of pain research

authors： Bakeer AH,Abdallah NM,Kamel MA,Abbas DN,Ragab AS

更新日期：2018-12-19 00:00:00

abstract：PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...

journal_title：Journal of pain research

authors： Bernaba M,Johnson KA,Kong JT,Mackey S

更新日期：2014-11-26 00:00:00

abstract：Purpose:This study aimed to review and pool the current literature on intra-articular ozone injection in knee osteoarthritis (OA) patients. Methods:A systematic review of three big databases was performed to identify all English-language randomized clinical trials (RCTs) that evaluated the efficacy of intra-articular ...

journal_title：Journal of pain research

authors： Raeissadat SA,Tabibian E,Rayegani SM,Rahimi-Dehgolan S,Babaei-Ghazani A

更新日期：2018-10-25 00:00:00

abstract：:Ultrasound-guided cervical nerve root block is the technique of injecting local anesthetic or steroid into the intertubercular groove outside of the cervical foramen under real-time ultrasound guidance. It has established diagnostic and therapeutic employment for patients suffering symptoms caused by cervical disc dis...

journal_title：Journal of pain research

authors： Zhang S,Fan L,Mei W

更新日期：2020-10-14 00:00:00

abstract：Purpose:No final conclusion has yet been reached on characteristics of postoperative pain and pain-related factors after video-assisted thoracoscopic surgery (VATS). This study was designed to explore features of acute severe pain and chronic post-surgical pain (CPSP), and the pain-related factors of VATS. Patients an...

journal_title：Journal of pain research

authors： Tong Y,Wei P,Wang S,Sun Q,Cui Y,Ning N,Chen S,He X

更新日期：2020-07-21 00:00:00

abstract：Background:Chronic shoulder pain (CSP) is a common disease causing pain and functional limitation, which is highly prevalent and has substantial negative effects on the quality of life. Acupuncture has gained popularity and has been accepted gradually by many countries because it can successfully treat patients with ch...

journal_title：Journal of pain research

authors： Zhang S,Wang X,Yan CQ,Hu SQ,Huo JW,Wang ZY,Zhou P,Liu CH,Liu CZ

更新日期：2018-03-07 00:00:00

abstract：PURPOSE:Medical clowning has proven effective for reducing pain, anxiety, and stress, however, its differential effects on children from different cultures have not yet been researched. This study evaluated the effects of medical-clowning intervention on anxiety and pain among Jewish and Bedouin children, and anxiety a...

journal_title：Journal of pain research

authors： Gilboa-Negari Z,Abu-Kaf S,Huss E,Hain G,Moser A

更新日期：2017-07-05 00:00:00

abstract：Background:With the increase in life expectancy seen throughout the world, the prevalence of degenerative spinal pathology and surgery to treat it has increased. Spinal surgery under general anesthesia leads to various problems and complications, especially in patients with numerous medical comorbidities or elderly pat...

journal_title：Journal of pain research

authors： Kang SY,Kashlan ON,Singh R,Rane R,Adsul NM,Jung SC,Yi J,Cho HS,Kim HS,Jang IT,Oh SH

更新日期：2020-01-21 00:00:00

abstract：Purpose:Undertreatment of trauma-related pain is common in the pre-hospital and hospital settings owing to barriers to the use of traditional standard of care analgesics. Low-dose methoxyflurane is an inhaled non-opioid analgesic with a rapid onset of pain relief that is approved for emergency relief of moderate-to-sev...

journal_title：Journal of pain research

authors： Fabbri A,Borobia AM,Ricard-Hibon A,Coffey F,Caumont-Prim A,Montestruc F,Soldi A,Traseira Lugilde S,Dickerson S

更新日期：2021-01-20 00:00:00

abstract：Background:It is becoming increasingly important to understand the mechanisms of spinal cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise. Purpose:Additionally, the small anatomic scale of current SCS animal models is a barrier to more translational research. Methods:Using ch...

journal_title：Journal of pain research

authors： Reddy CG,Miller JW,Abode-Iyamah KO,Safayi S,Wilson S,Dalm BD,Fredericks DC,Gillies GT,Howard MA 3rd,Brennan TJ

更新日期：2018-06-15 00:00:00

abstract：:Mechanisms of postherpetic neuralgia (PHN) are still not clear. Transcripts such as microRNA (miRNA) and circular RNA (circRNA) in the affected skin may take part in the initiation and development of this neuropathic pain; however, their expression profiles in skins of PHN patients have not been reported. The PHN affe...

journal_title：Journal of pain research

authors： Cao S,Zhang D,Yuan J,Liu C,Zhou W,Zhang L,Yu S,Qin B,Li Y,Deng W

更新日期：2019-10-16 00:00:00

abstract：:Generalized joint hypermobility (GJH) is highly prevalent among patients diagnosed with chronic pain. When GJH is accompanied by pain in ≥4 joints over a period ≥3 months in the absence of other conditions that cause chronic pain, the hypermobility syndrome (HMS) may be diagnosed. In addition, GJH is also a clinical s...

journal_title：Journal of pain research

authors： Scheper MC,de Vries JE,Verbunt J,Engelbert RH

更新日期：2015-08-20 00:00:00

abstract：BACKGROUND:Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. METHODS:This prospective, observational study evaluated changes from bas...

journal_title：Journal of pain research

authors： Gudin JA,Brennan MJ,Harris ED,Hurwitz PL,Dietze DT,Strader JD

更新日期：2017-10-03 00:00:00

abstract：Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...

journal_title：Journal of pain research

authors： Freo U,Furnari M,Ori C

更新日期：2018-09-13 00:00:00