Muscle injections with lidocaine improve resting fatigue and pain in patients with chronic fatigue syndrome.

abstract：:Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as w...

journal_title：Journal of pain research

authors： Knotkova H,Cruciani RA,Tronnier VM,Rasche D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the safety, tolerability, and preliminary efficacy of NGX-4010, a capsaicin 8% patch, following pretreatment with three different topical anesthetics in patients with peripheral neuropathic pain. METHODS:This open-label, multicenter study enrolled 117 patients with ...

journal_title：Journal of pain research

authors： Webster LR,Peppin JF,Murphy FT,Tobias JK,Vanhove GF

更新日期：2012-01-01 00:00:00

abstract：Background:Postherpetic neuralgia (PHN) refers to pain which remains after the healing of rashes from herpes zoster. Previous literatures have shown that acupuncture has potential benefits for PHN, but evidence remains lacking. Thus, we have performed a systematic review and meta-analysis to identify the effectiveness ...

journal_title：Journal of pain research

authors： Pei W,Zeng J,Lu L,Lin G,Ruan J

更新日期：2019-07-16 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is a major player in migraine pathophysiology, and CGRP monoclonal antibodies including fremanezumab may be a safe effective preventive therapy. Phase IIb studies in episodic migraine (EM) and chronic migraine (CM) demonstrated efficacy at both the monthly 225 mg and quarterly 67...

journal_title：Journal of pain research

authors： Robblee J,VanderPluym J

更新日期：2019-08-22 00:00:00

abstract：Background:With the increase in life expectancy seen throughout the world, the prevalence of degenerative spinal pathology and surgery to treat it has increased. Spinal surgery under general anesthesia leads to various problems and complications, especially in patients with numerous medical comorbidities or elderly pat...

journal_title：Journal of pain research

authors： Kang SY,Kashlan ON,Singh R,Rane R,Adsul NM,Jung SC,Yi J,Cho HS,Kim HS,Jang IT,Oh SH

更新日期：2020-01-21 00:00:00

abstract：Aim:Operant conditioning has long been believed to influence the pain experience through a psychological reward pathway. This study was formulated to test the hypothesis that pain sensitivity may be enhanced >3 months if a monetary reward works as a reinforcement. Methods:Forty healthy subjects volunteered to particip...

journal_title：Journal of pain research

authors： Shiro Y,Ikemoto T,Hayashi K,Arai YC,Deie M,Ueno T

更新日期：2018-10-04 00:00:00

abstract：Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...

journal_title：Journal of pain research

authors： Chakravarthy K,Bink H,Dinsmoor D

更新日期：2020-12-04 00:00:00

abstract：:Purpose: We aimed to explore the characteristics, and real-life therapeutic management of patients with breakthrough cancer pain (BTcP) caused by bone metastases in Spain, and to evaluate physicians' opinion of and satisfaction with prescribed BTcP therapy. Participants and methods: For the purposes of this study, an ...

journal_title：Journal of pain research

authors： Ferrer Albiach C,Villegas Estévez F,López Alarcón MD,de Madariaga M,Carregal A,Arranz J,Trinidad Martín-Arroyo JM,Jiménez López AJ,Sanz Yagüe A

更新日期：2019-07-12 00:00:00

abstract：Purpose:Undertreatment of trauma-related pain is common in the pre-hospital and hospital settings owing to barriers to the use of traditional standard of care analgesics. Low-dose methoxyflurane is an inhaled non-opioid analgesic with a rapid onset of pain relief that is approved for emergency relief of moderate-to-sev...

journal_title：Journal of pain research

authors： Fabbri A,Borobia AM,Ricard-Hibon A,Coffey F,Caumont-Prim A,Montestruc F,Soldi A,Traseira Lugilde S,Dickerson S

更新日期：2021-01-20 00:00:00

abstract：Background:Despite the increasing prevalence of opioid use disorder (OUD) in pregnant women, there are limited studies on their anesthesia care and analgesic outcomes after cesarean delivery (CD). Methods:Patients with OUD on either buprenorphine or methadone maintenance therapy who underwent CD at our institution fro...

journal_title：Journal of pain research

authors： Reno JL,Kushelev M,Coffman JH,Prasad MR,Meyer AM,Carpenter KM,Palettas MS,Coffman JC

更新日期：2020-12-30 00:00:00

abstract：Objectives:The primary aim was to assess the psychometric properties (including internal consistency, construct validity, criterion validity, criterion-group validity and responsiveness) of the Fear of Pain Questionnaire (FOPQ) for adolescents (FOPQ-A) and parents (FOPQ-P) translated to Brazilian Portuguese (BrP). The ...

journal_title：Journal of pain research

authors： Berniger Romariz JA,Nonnemacher C,Abreu M,Dickel Segabinazi J,Bandeira JS,Beltran G,Souza A,Torres IL,Caumo W

更新日期：2019-08-07 00:00:00

abstract：INTRODUCTION:Pain is a common symptom presented in the emergency department (ED) although it is often underestimated, poorly evaluated and treated. The application of a protocol for timely pain management ensured by the nurse can avoid the delays in the analgesic treatment and improve the patient's quality of waiting. ...

journal_title：Journal of pain research

authors： Butti L,Bierti O,Lanfrit R,Bertolini R,Chittaro S,Delli Compagni S,Del Russo D,Mancusi RL,Pertoldi F

更新日期：2017-10-16 00:00:00

abstract：Purpose:Epidural analgesia provides safe and effective labor pain relief. However, labor episodic pain can occur during epidural analgesia, requiring epidural top-ups, and may result in decreased patient satisfaction. The primary aim of our study was to investigate the factors associated with labor episodic pain during...

journal_title：Journal of pain research

authors： Chan JJI,Gan YY,Dabas R,Han NR,Sultana R,Sia ATH,Sng BL

更新日期：2019-02-15 00:00:00

abstract：Background:Acupotomy, which involves the addition of a scalpel function to the conventional acupuncture treatment, has recently been applied as a conservative treatment method for lumbar disc herniation (LDH). This study investigated the effectiveness and safety of acupotomy, compared to manual acupuncture, for the tre...

journal_title：Journal of pain research

authors： Jeong JK,Kim E,Yoon KS,Jeon JH,Kim YI,Lee H,Kwon O,Jung SY,Lee JH,Yang C,Kang JH,Han CH

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:Chronic neuropathic pain and chronic complex regional pain syndrome (CRPS), in particular, are debilitating and difficult-to-treat conditions that have a strong impact on patient's quality of life. The aim of this study was to evaluate the effectiveness of 5% lidocaine-medicated plaster as add-on therapy in ...

journal_title：Journal of pain research

authors： Calderón E,Calderón-Seoane ME,García-Hernández R,Torres LM

更新日期：2016-10-06 00:00:00

abstract：Purpose:Primary dysmenorrhea (PD; menstrual pain without an identified organic cause) has been proposed as a possible risk factor for the development of chronic pelvic pain, but the mechanism through which this process occurs is unknown. One possible mechanism is central sensitization - alterations in the central nervo...

journal_title：Journal of pain research

authors： Seidman LC,Temme CR,Zeltzer LK,Rapkin AJ,Naliboff BD,Payne LA

更新日期：2020-12-22 00:00:00

abstract：Background:To date, there has been no study on the effects of interleukin-10 (IL-10) on complex regional pain syndrome (CRPS) rodent models, despite the anti-allodynic effect of IL-10 in previous studies. Thus, the aim of this study was to investigate the effect of IL-10 in a CRPS mouse model and find whether early inh...

journal_title：Journal of pain research

authors： Kim JH,Park JS,Park D

更新日期：2018-09-04 00:00:00

abstract：BACKGROUND:No proof of efficacy, in the form of a randomized controlled trial (RCT), exists to support pulsed radiofrequency (PRF) treatment of the dorsal root ganglion (DRG) for chronic lumbar radicular (CLR) pain. We determined the feasibility of a larger trial (primary objective), and also explored the efficacy of P...

journal_title：Journal of pain research

authors： Shanthanna H,Chan P,McChesney J,Thabane L,Paul J

更新日期：2014-01-10 00:00:00

abstract：Aim:In chronic pain, habituation is believed to be impaired, and pain hypervigilance can enhance the pain experience. The goal of this study was to determine whether pain hypervigilance further worsens habituation of event-related potentials, measured in a pain-rating protocol of 25 painful somatosensory electrical sti...

journal_title：Journal of pain research

authors： Vossen CJ,Luijcks R,van Os J,Joosten EA,Lousberg R

更新日期：2018-02-19 00:00:00

abstract：Purpose:Post-herpetic neuralgia (PHN) is a common herpes zoster (HZ) complication, where pain persists 90 days after the initial HZ diagnosis. Evaluating PHN risk is essential for determining the burden on patients and health-care systems, but research shows variable estimates. The extent to which these differences are...

journal_title：Journal of pain research

authors： Tanenbaum HC,Lawless A,Sy LS,Hong V,Ackerson B,Bruxvoort K,Luo Y,Tseng HF

更新日期：2020-07-13 00:00:00

abstract：:Mechanisms of postherpetic neuralgia (PHN) are still not clear. Transcripts such as microRNA (miRNA) and circular RNA (circRNA) in the affected skin may take part in the initiation and development of this neuropathic pain; however, their expression profiles in skins of PHN patients have not been reported. The PHN affe...

journal_title：Journal of pain research

authors： Cao S,Zhang D,Yuan J,Liu C,Zhou W,Zhang L,Yu S,Qin B,Li Y,Deng W

更新日期：2019-10-16 00:00:00

abstract：Background:G protein-gated inwardly rectifying potassium (GIRK) channels are involved in the regulation of neuronal excitability. Four GIRK subunits (GIRK1-4) are expressed in rat dorsal root ganglia (DRGs). Recently, we have characterized the expression of GIRK1 and -2, and both are downregulated in rat DRGs and spina...

journal_title：Journal of pain research

authors： Lyu C,Lyu GW,Mulder J,Martinez A,Shi TS

更新日期：2020-02-17 00:00:00

abstract：Background:It is becoming increasingly important to understand the mechanisms of spinal cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise. Purpose:Additionally, the small anatomic scale of current SCS animal models is a barrier to more translational research. Methods:Using ch...

journal_title：Journal of pain research

authors： Reddy CG,Miller JW,Abode-Iyamah KO,Safayi S,Wilson S,Dalm BD,Fredericks DC,Gillies GT,Howard MA 3rd,Brennan TJ

更新日期：2018-06-15 00:00:00

abstract：UNLABELLED:Postsurgical pain management remains a significant challenge. Liposome bupivacaine, as part of a multimodal analgesic regimen, has been shown to significantly reduce postsurgical opioid consumption, hospital length of stay (LOS), and hospitalization costs in gastrointestinal (GI) surgery, compared with intra...

journal_title：Journal of pain research

authors： Cohen SM,Vogel JD,Marcet JE,Candiotti KA

更新日期：2014-06-24 00:00:00

abstract：Purpose:To identify risk factors for pain after transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Patients and Methods:In this retrospective study, a total of 118 consecutive patients who underwent DEB-TACE between June 2016 and May 2019 with post-TACE pain were inc...

journal_title：Journal of pain research

authors： Wang TC,Zhang ZS,Xiao YD

更新日期：2020-03-27 00:00:00

abstract：:Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 yea...

journal_title：Journal of pain research

authors： Sofat N,Harrison A,Russell MD,Ayis S,Kiely PD,Baker EH,Barrick TR,Howe FA

更新日期：2017-10-10 00:00:00

abstract：Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...

journal_title：Journal of pain research

authors： Qiu Y,Zhang TJ,Hua Z

更新日期：2020-07-01 00:00:00

abstract：Background:Although the Eph receptor plays an important role in the development of neuropathic pain following nerve injury, there has been no evidence of the participation of the ephrin A4 receptor (EphA4) in the development of trigeminal neuropathic pain. The present study investigated the role of EphA4 in central noc...

journal_title：Journal of pain research

authors： Kim MJ,Son JY,Ju JS,Ahn DK

更新日期：2020-05-22 00:00:00

abstract：OBJECTIVE:To characterize the steady-state pharmacokinetic profile of hydromorphone extended-release (ER) in patients with chronic pain taking concomitant medications. METHODS:This open-label repeat-dose study enrolled 22 patients (mean age, 51.4 years; 81.8% female). All patients were receiving at least one concomita...

journal_title：Journal of pain research

authors： Vandenbossche J,Richarz U,Richards HM

更新日期：2012-01-01 00:00:00

abstract：Background:It has been reported that N-cadherin and cAMP response element binding protein (CREB) in the spinal cord are critical for synaptogenesis and regulation of excitatory synapse function, which could underlie chronic pain development. The aim of the present study was to investigate the role of spinal N-cadherin/...

journal_title：Journal of pain research

authors： Ma Y,Zhang X,Li C,Liu S,Xing Y,Tao F

更新日期：2020-08-12 00:00:00