The effect of pregabalin or duloxetine on arthritis pain: a clinical and mechanistic study in people with hand osteoarthritis.

abstract：Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...

journal_title：Journal of pain research

authors： Qiu Y,Zhang TJ,Hua Z

更新日期：2020-07-01 00:00:00

abstract：:Mechanisms of postherpetic neuralgia (PHN) are still not clear. Transcripts such as microRNA (miRNA) and circular RNA (circRNA) in the affected skin may take part in the initiation and development of this neuropathic pain; however, their expression profiles in skins of PHN patients have not been reported. The PHN affe...

journal_title：Journal of pain research

authors： Cao S,Zhang D,Yuan J,Liu C,Zhou W,Zhang L,Yu S,Qin B,Li Y,Deng W

更新日期：2019-10-16 00:00:00

abstract：Aim:Operant conditioning has long been believed to influence the pain experience through a psychological reward pathway. This study was formulated to test the hypothesis that pain sensitivity may be enhanced >3 months if a monetary reward works as a reinforcement. Methods:Forty healthy subjects volunteered to particip...

journal_title：Journal of pain research

authors： Shiro Y,Ikemoto T,Hayashi K,Arai YC,Deie M,Ueno T

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:Cutaneous allodynia (CA) is a common feature of migraine, which has a complex underlying pathophysiology that is not well understood. In addition to pain, photophobia, phonophobia, osmophobia, nausea, and vomiting, CA can contribute to the overall disability caused by migraine. The presence of CA can be esta...

journal_title：Journal of pain research

authors： Mathew PG,Cutrer FM,Garza I

更新日期：2016-02-24 00:00:00

abstract：:Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, some...

journal_title：Journal of pain research

authors： Keppel Hesselink JM,Kopsky DJ,Sajben N

更新日期：2016-10-03 00:00:00

abstract：Background:The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF). Materials and methods:The records ...

journal_title：Journal of pain research

authors： Zhou J,Li L,Li T,Xue Y

更新日期：2018-10-26 00:00:00

abstract：BACKGROUND:Detecting the efficacy of novel analgesic agents in neuropathic pain is challenging. There is a critical need for study designs with the desirable characteristics of assay sensitivity, low placebo response, reliable pain recordings, low cost, short duration of exposure to test drug and placebo, and relevant ...

journal_title：Journal of pain research

authors： Jenkins TM,Smart TS,Hackman F,Cooke C,Tan KK

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:The zona incerta (ZI) is below the ventral tier of the thalamus and has a strong influence selectively in higher-order thalamic relays. Although neuropathic pain has been suggested to result from reduced gamma-aminobutyric acid (GABA) and GABAergic signaling in the ZI, the mechanisms remain unclear. Here, the r...

journal_title：Journal of pain research

authors： Moon HC,Park YS

更新日期：2017-05-11 00:00:00

abstract：Background:Low back pain is a prevalent symptom that occurs in all age of people, whereas the pathogenesis is unknown. Iliopsoas tendinopathy is an increasingly recognized hip disorder that may contribute to low back pain. Our purpose is to evaluate the effect of ultrasound-guided local injection of anesthetic and ster...

journal_title：Journal of pain research

authors： Zhu Z,Zhang J,Sheng J,Zhang C,Xie Z

更新日期：2020-11-20 00:00:00

abstract：PURPOSE:The treatment of central neuropathic pain remains amongst the biggest challenges for pain specialists. The main objective of this study was to assess gabapentin (GBP), amitriptyline (AMI), and carbamazepine (CARBA) for the treatment of a rodent central neuropathic pain model. METHODS:Male Sprague Dawley rats w...

journal_title：Journal of pain research

authors： Castel A,Vachon P

更新日期：2013-12-17 00:00:00

abstract：:A 41-year-old woman presented with burning and erythema in her extremities triggered by warmth and activity, which was relieved by applying ice. Extensive workup was consistent with adult-onset primary erythromelalgia (EM). Several pharmacological treatments were tried including local anesthetics, capsaicin, ziconotid...

journal_title：Journal of pain research

authors： Low SA,Robbins W,Tawfik VL

更新日期：2017-04-27 00:00:00

abstract：Background and Aims:Plantar fasciitis (PF) is the leading cause of heel pain in adults. This study was designed to evaluate the effect of hyaluronic acid (HA) injection in reducing the symptoms of PF, compared with corticosteroid (CS) injection as a conventional treatment. Methods:In this triple-blind, randomized, cli...

journal_title：Journal of pain research

authors： Raeissadat SA,Nouri F,Darvish M,Esmaily H,Ghazihosseini P

更新日期：2020-01-14 00:00:00

abstract：Background:Many aspects of study conduct impact the observed effect size of treatment. Data were utilized from a recently published meta-analysis of randomized, double-blind, placebo-controlled, clinical trials performed for the United States Food and Drug Administration (FDA) approval of full mu-agonist opioids for th...

journal_title：Journal of pain research

authors： Meske DS,Vaughn BJ,Kopecky EA,Katz N

更新日期：2019-11-20 00:00:00

abstract：Background:Although the Eph receptor plays an important role in the development of neuropathic pain following nerve injury, there has been no evidence of the participation of the ephrin A4 receptor (EphA4) in the development of trigeminal neuropathic pain. The present study investigated the role of EphA4 in central noc...

journal_title：Journal of pain research

authors： Kim MJ,Son JY,Ju JS,Ahn DK

更新日期：2020-05-22 00:00:00

abstract：BACKGROUND:Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, t...

journal_title：Journal of pain research

authors： Fanelli G,De Carolis G,Leonardi C,Longobardi A,Sarli E,Allegri M,Schatman ME

更新日期：2017-05-22 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Major abdominal cancer surgeries are associated with significant perioperative mortality and morbidity due to myocardial ischemia and infarction. This study examined the effect of perioperative patient controlled epidural analgesia (PCEA) on occurrence of ischemic cardiac injury in ischemic pa...

journal_title：Journal of pain research

authors： Mohamad MF,Mohammad MA,Hetta DF,Ahmed EH,Obiedallah AA,Elzohry AAM

更新日期：2017-04-12 00:00:00

abstract：:The observation of pain in others may enhance or reduce self-pain, yet the boundary conditions and factors that determine the direction of such effects are poorly understood. The current study set out to show that visual stimulus awareness plays a crucial role in determining whether vicarious pain primarily activates ...

journal_title：Journal of pain research

authors： Terrighena EL,Lu G,Yuen WP,Lee TM,Keuper K

更新日期：2017-07-31 00:00:00

abstract：Background:Patients living with chronic upper limb and neck (ULN) pain are reliant on often ineffective therapies as they face limited options for effective long-term treatment. Objective:Prospective clinical studies have demonstrated that high-frequency spinal cord stimulation at 10 kHz (10 kHz SCS) is effective in t...

journal_title：Journal of pain research

authors： Sayed D,Salmon J,Khan TW,Sack AM,Braun T,Barnard A,Rotte A

更新日期：2020-06-15 00:00:00

abstract：:Diabetic peripheral neuropathy (DPN) represents significant burdens to many patients and the public health-care system. Patients with diabetes in rural areas have higher risk of developing complications and having less access to proper treatment. We studied a rural population of patients with diabetes who attended a p...

journal_title：Journal of pain research

authors： Pruitt J 3rd,Moracho-Vilrriales C,Threatt T,Wagner S,Wu J,Romero-Sandoval EA

更新日期：2017-04-07 00:00:00

abstract：BACKGROUND:Several studies have illustrated that multisite pain is more frequent than single pain site, and it is associated with an array of negative consequences. However, there is limited knowledge available about the potential factors associated with multisite pain in the elderly general population. OBJECTIVE:This...

journal_title：Journal of pain research

authors： Dragioti E,Larsson B,Bernfort L,Levin LÅ,Gerdle B

更新日期：2017-08-23 00:00:00

abstract：BACKGROUND:While studies have demonstrated the economic burden of migraines in terms of quality of life, health care resource use (HRU), and costs, there exists a notable paucity of data comparing such outcomes among migraineurs with nausea and vomiting (N/V) and those without. The current study aimed to address this g...

journal_title：Journal of pain research

authors： Gajria K,Lee LK,Flores NM,Aycardi E,Gandhi SK

更新日期：2017-03-24 00:00:00

abstract：Background:Millions of people worldwide are suffering from pain. Non-pharmacological therapy has an important role in the treatment of pain and is recognized as a valuable, simple help to lower the dosage of analgesic drugs needed, decreasing the side effects, reducing drug dependency and reducing health care costs; ho...

journal_title：Journal of pain research

authors： Jira L,Weyessa N,Mulatu S,Alemayehu A

更新日期：2020-11-16 00:00:00

abstract：:Purpose: The objective for this clinical pilot study was to evaluate changes to chronic pain, vascular health, and inflammatory markers when consuming a dietary supplement blend (DSB, CytoQuel®), containing curcumin, resveratrol, tocotrienols, N-Acetylcysteine, and epigallocatechin gallate. Materials and methods: An o...

journal_title：Journal of pain research

authors： Hamilton DE,Jensen GS

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:One form of self-medication is sharing of medications, defined as borrowing or lending medications in situations where the receiver of these drugs is not the individual to whom the medications were allocated. OBJECTIVE:To explore experiences and opinions of patients about sharing prescription analgesics, re...

journal_title：Journal of pain research

authors： Markotic F,Vrdoljak D,Puljiz M,Puljak L

更新日期：2017-02-10 00:00:00

abstract：Background:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis patients often present with psychiatric symptoms, cognitive dysfunction, epilepsy and memory deficits. A previous study has suggested that headache can occurr during the early stages of anti-NMDAR encephalitis. However, the exact association between hea...

journal_title：Journal of pain research

authors： Ma C,Wang C,Zhang Q,Lian Y

更新日期：2019-01-30 00:00:00

abstract：OBJECTIVES:Chronic neuropathic pain and chronic complex regional pain syndrome (CRPS), in particular, are debilitating and difficult-to-treat conditions that have a strong impact on patient's quality of life. The aim of this study was to evaluate the effectiveness of 5% lidocaine-medicated plaster as add-on therapy in ...

journal_title：Journal of pain research

authors： Calderón E,Calderón-Seoane ME,García-Hernández R,Torres LM

更新日期：2016-10-06 00:00:00

abstract：Background:Cast immobilization is the primary treatment for children with forearm fractures. After emergency department (ED) discharge, some patients develop cast-related pain (CstRP) around the distal part of the upper extremity. We examined variables associated with ED revisits due to CstRP in children with forearm f...

journal_title：Journal of pain research

authors： Kvatinsky N,Carmiel R,Leiba R,Shavit I

更新日期：2020-01-08 00:00:00

abstract：Purpose:Post-herpetic neuralgia (PHN) is a common herpes zoster (HZ) complication, where pain persists 90 days after the initial HZ diagnosis. Evaluating PHN risk is essential for determining the burden on patients and health-care systems, but research shows variable estimates. The extent to which these differences are...

journal_title：Journal of pain research

authors： Tanenbaum HC,Lawless A,Sy LS,Hong V,Ackerson B,Bruxvoort K,Luo Y,Tseng HF

更新日期：2020-07-13 00:00:00

abstract：OBJECTIVE:Patients with chronic fatigue syndrome (CFS) complain of long-lasting fatigue and pain which are not relieved by rest and worsened by physical exertion. Previous research has implicated metaboreceptors of muscles to play an important role for chronic fatigue and pain. Therefore, we hypothesized that blocking ...

journal_title：Journal of pain research

authors： Staud R,Kizer T,Robinson ME

更新日期：2017-06-26 00:00:00

abstract：Purpose:Complex regional pain syndrome (CRPS) is a rare but refractory pain disorder. Recent advanced information retrieval studies using text-mining and network analysis have suggested nuclear factor kappa B (NFκB) as a possible central mediator of CRPS. The brain is also known to play important roles in CRPS. The aim...

journal_title：Journal of pain research

authors： Nahm FS,Nahm SS,Han WK,Gil HY,Choi E,Lee PB

更新日期：2019-03-06 00:00:00