A cross-sectional study of factors associated with the number of anatomical pain sites in an actual elderly general population: results from the PainS65+ cohort.

Abstract:

BACKGROUND:Several studies have illustrated that multisite pain is more frequent than single pain site, and it is associated with an array of negative consequences. However, there is limited knowledge available about the potential factors associated with multisite pain in the elderly general population. OBJECTIVE:This cross-sectional study examines whether the number of anatomical pain sites (APSs) is related to sociodemographic and health-related factors in older adults including oldest-old ages using a new method (APSs) to assess the location of pain on the body. MATERIALS AND METHODS:The sample came from the PainS65+ cohort, which included 6,611 older individuals (mean age = 76.0 years; standard deviation [SD] = 7.4) residing in southeastern Sweden. All the participants completed and returned a postal survey that measured sociodemographic data, total annual income, pain intensity and frequency, general well-being, and quality of life. The number of pain sites (NPS) was marked on a body manikin of 45 sections, and a total of 23 APSs were then calculated. Univariable and multivariable models of regression analysis were performed. RESULTS:Approximately 39% of the respondents had at least two painful sites. The results of the regression analysis showed an independent association between the APSs and the age group of 75-79 years, women, married, high pain intensity and frequency, and low well-being and quality of life, after adjustments for consumption of analgesics and comorbidities. The strongest association was observed for the higher frequency of pain. CONCLUSION:Our results suggest that APSs are highly prevalent with strong relationships with various sociodemographic and health-related factors and concur well with the notion that multisite pain is a potential indicator of increased pain severity and impaired quality of life in the elderly. Our comprehensive method of calculating the number of sites could be an essential part of the clinical presentation, assessment, and treatment of multisite pain.

journal_name

J Pain Res

journal_title

Journal of pain research

authors

Dragioti E,Larsson B,Bernfort L,Levin LÅ,Gerdle B

doi

10.2147/JPR.S143060

subject

Has Abstract

pub_date

2017-08-23 00:00:00

pages

2009-2019

issn

1178-7090

pii

jpr-10-2009

journal_volume

10

pub_type

杂志文章
  • To what extent are patients with migraine able to predict attacks?

    abstract:Purpose:Premonitory symptoms (PSs) of migraine are those that precede pain in a migraine attack. Previous studies suggest that treatment during this phase may prevent the onset of pain; however, this approach requires that patients be able to recognize their PSs. Our objectives were to evaluate patients' actual ability...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S175602

    authors: Gago-Veiga AB,Pagán J,Henares K,Heredia P,González-García N,De Orbe MI,Ayala JL,Sobrado M,Vivancos J

    更新日期:2018-09-27 00:00:00

  • Caregivers' knowledge and acceptance of complementary and alternative medicine in a tertiary care pediatric hospital.

    abstract:Background:The use of complementary and alternative medicine (CAM) therapies has increased in children, especially in those with chronic health conditions. However, this increase may not translate into acceptance of CAM in the perioperative setting. We surveyed caregivers of patients undergoing surgery to determine the...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S156585

    authors: Trifa M,Tumin D,Walia H,Lemanek KL,Tobias JD,Bhalla T

    更新日期:2018-03-01 00:00:00

  • Diclofenac epolamine topical patch relieves pain associated with ankle sprain.

    abstract:BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S15380

    authors: Lionberger DR,Joussellin E,Lanzarotti A,Yanchick J,Magelli M

    更新日期:2011-03-07 00:00:00

  • The impact of multisite pain on functional outcomes in older adults: biopsychosocial considerations.

    abstract::Multisite pain, or pain that occurs simultaneously at >1 anatomical site, is more prevalent than single-site pain. While multisite pain affects over half of older adults, it remains an understudied pain entity that may have important functional implications in an aging population. Greater understanding of this complex...

    journal_title:Journal of pain research

    pub_type: 杂志文章,评审

    doi:10.2147/JPR.S192755

    authors: Butera KA,Roff SR,Buford TW,Cruz-Almeida Y

    更新日期:2019-03-29 00:00:00

  • The prevalence of probable neuropathic pain in the US: results from a multimodal general-population health survey.

    abstract:Background:The prevalence of neuropathic pain (NeP) has been estimated within specific health conditions; however, there are no published data on its broad prevalence in the US. The current exploratory study addresses this gap using the validated PainDetect questionnaire as a screener for probable NeP in a general-popu...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S127014

    authors: DiBonaventura MD,Sadosky A,Concialdi K,Hopps M,Kudel I,Parsons B,Cappelleri JC,Hlavacek P,Alexander AH,Stacey BR,Markman JD,Farrar JT

    更新日期:2017-11-01 00:00:00

  • Effects of transversus abdominis plane blocks after hysterectomy: a meta-analysis of randomized controlled trials.

    abstract:Background:Transversus abdominis plane (TAP) block can provide effective analgesia for abdominal surgery. However, many randomized controlled trials (RCTs) have shown controversial results in hysterectomy. We conducted a meta-analysis of RCTs to investigate the effectiveness of TAP block after hysterectomy. Methods:St...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S172828

    authors: Zhou H,Ma X,Pan J,Shuai H,Liu S,Luo X,Li R

    更新日期:2018-10-18 00:00:00

  • Effects of tapentadol on pain, motor symptoms and cognitive functions in Parkinson's disease.

    abstract:Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S164939

    authors: Freo U,Furnari M,Ori C

    更新日期:2018-09-13 00:00:00

  • What is adolescent low back pain? Current definitions used to define the adolescent with low back pain.

    abstract::Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/jpr.s10025

    authors: Milanese S,Grimmer-Somers K

    更新日期:2010-05-17 00:00:00

  • Association between lymphocyte expression of the apoptotic receptor Fas and pain in critically ill patients.

    abstract:OBJECTIVE:Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH)...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S118105

    authors: Papathanassoglou E,Mpouzika MD,Giannakopoulou M,Bozas E,Middleton N,Tsiaousis G,Karabinis A

    更新日期:2017-01-13 00:00:00

  • Cannabis and intractable chronic pain: an explorative retrospective analysis of Italian cohort of 614 patients.

    abstract:BACKGROUND:Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, t...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S132814

    authors: Fanelli G,De Carolis G,Leonardi C,Longobardi A,Sarli E,Allegri M,Schatman ME

    更新日期:2017-05-22 00:00:00

  • Regional Differences in Opioid Prescribing in Germany - Results of an Analysis of Health Insurance Data of 57 Million Adult People.

    abstract:Background:Regional variations of opioid use have been reported from many countries. The objective of this study was to examine opioid prescribing patterns in Germany including low- and high-potency opioids (LPO and HPO) focusing on regional differences. Methods:Data source was the "Information system for health care ...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S259009

    authors: Jobski K,Dörks M,Bantel C,Hoffmann F

    更新日期:2020-10-07 00:00:00

  • New topical treatment of vulvodynia based on the pathogenetic role of cross talk between nociceptors, immunocompetent cells, and epithelial cells.

    abstract::Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, some...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S115407

    authors: Keppel Hesselink JM,Kopsky DJ,Sajben N

    更新日期:2016-10-03 00:00:00

  • Sensing Evoked Compound Action Potentials from the Spinal Cord: Novel Preclinical and Clinical Considerations for the Pain Management Researcher and Clinician.

    abstract:Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S289098

    authors: Chakravarthy K,Bink H,Dinsmoor D

    更新日期:2020-12-04 00:00:00

  • Short-term incubation of gabapentin or pregabalin does not affect chemically induced injury in neuronal cell models in vitro.

    abstract:Purpose:Gabapentinoids are currently the mainstay of pharmacological treatments for patients with neuropathic pain. Little is known about the effects of this therapy on the integrity of neuronal networks, especially in patients with an already-damaged nervous system. Since gabapentinoids can worsen cognitive functions ...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S162322

    authors: Baldewig M,Goldbaum O,Richter-Landsberg C,Weyland A,Bantel C

    更新日期:2018-06-20 00:00:00

  • The impact of anxiety and catastrophizing on interleukin-6 responses to acute painful stress.

    abstract:Objective:To examine the influence of anxiety and pain-related catastrophizing on the time course of acute interleukin-6 (IL-6) responses to standardized noxious stimulation among patients with chronic pain. Methods:Data were collected from 48 participants in the following demographically matched groups: patients with...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S147735

    authors: Lazaridou A,Martel MO,Cahalan CM,Cornelius MC,Franceschelli O,Campbell CM,Haythornthwaite JA,Smith M,Riley J,Edwards RR

    更新日期:2018-03-28 00:00:00

  • Age-related and sex-related changes in perfusion index in response to noxious electrical stimulation in healthy subjects.

    abstract:BACKGROUND:Even though pain is a subjective phenomenon, its objective evaluation in humans is important because subjects requiring pain evaluation may be unable to describe their pain intensity because of decreased awareness or impaired cognitive function. Previous reports indicate that the perfusion index (PI), which ...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S57140

    authors: Nishimura T,Nakae A,Shibata M,Mashimo T,Fujino Y

    更新日期:2014-02-10 00:00:00

  • The challenge of developing pain medications for children: therapeutic needs and future perspectives.

    abstract::It is broadly accepted that children of all age groups including (preterm) neonates and young infants can perceive pain and that there is an absolute need to treat their pain safely and effectively. The approved treatment options for children, particularly (preterm) neonates and young infants, are very limited with on...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S195788

    authors: Eerdekens M,Beuter C,Lefeber C,van den Anker J

    更新日期:2019-05-23 00:00:00

  • Fear of pain potentiates nocebo hyperalgesia.

    abstract::Nocebo hyperalgesia has received sparse experimental attention compared to placebo analgesia. The aim of the present study was to investigate if personality traits and fear of pain could predict experimental nocebo hyperalgesia. One hundred and eleven healthy volunteers (76 females) participated in an experimental stu...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S91923

    authors: Aslaksen PM,Lyby PS

    更新日期:2015-10-12 00:00:00

  • Review of extended-release formulations of Tramadol for the management of chronic non-cancer pain: focus on marketed formulations.

    abstract::Patients with chronic non-malignant pain report impairments of physical, social, and psychological well-being. The goal of pain management should include reducing pain and improving quality of life. Patients with chronic pain require medications that are able to provide adequate pain relief, have minimum dosing interv...

    journal_title:Journal of pain research

    pub_type: 杂志文章,评审

    doi:10.2147/JPR.S49502

    authors: Kizilbash A,Ngô-Minh CT

    更新日期:2014-03-24 00:00:00

  • Problems and barriers of pain management in the emergency department: Are we ever going to get better?

    abstract::Pain is the most common reason people visit emergency rooms. Pain does not discriminate on the basis of gender, race or age. The state of pain management in the emergency department (ED) is disturbing. ED physicians often do not provide adequate analgesia to their patients, do not meet patients' expectations in treati...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:

    authors: Motov SM,Khan AN

    更新日期:2008-12-09 00:00:00

  • Differences in Estimates of Post-Herpetic Neuralgia Between Medical Chart Review and Self-Report.

    abstract:Purpose:Post-herpetic neuralgia (PHN) is a common herpes zoster (HZ) complication, where pain persists 90 days after the initial HZ diagnosis. Evaluating PHN risk is essential for determining the burden on patients and health-care systems, but research shows variable estimates. The extent to which these differences are...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S255238

    authors: Tanenbaum HC,Lawless A,Sy LS,Hong V,Ackerson B,Bruxvoort K,Luo Y,Tseng HF

    更新日期:2020-07-13 00:00:00

  • Comparison of the transport of QX-314 through TRPA1, TRPM8, and TRPV1 channels.

    abstract:BACKGROUND:It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing of nociceptors. The p...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S41614

    authors: Nakagawa H,Hiura A

    更新日期:2013-01-01 00:00:00

  • Patient-controlled analgesia in the pediatric population: morphine versus hydromorphone.

    abstract:OBJECTIVE:Patient controlled analgesia (PCA) is commonly used to provide analgesia following surgical procedures in the pediatric population. Morphine and hydromorphone remain the most commonly used opioids for PCA. Although both are effective, adverse effects may occur. When these adverse effects are unremitting or se...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S64497

    authors: DiGiusto M,Bhalla T,Martin D,Foerschler D,Jones MJ,Tobias JD

    更新日期:2014-08-13 00:00:00

  • Analysis of the clinical effects of transforaminal endoscopic discectomy on lumbar disk herniation combined with common peroneal nerve paralysis: a 2-year follow-up retrospective study on 32 patients.

    abstract:BACKGROUND:Very few studies have discussed transforaminal endoscopic discectomy (TED) in the treatment of common peroneal nerve paralysis induced by lumbar disk herniation (LDH). This study aimed to evaluate the efficacy of TED in the treatment of LDH combined with common peroneal nerve paralysis. MATERIALS AND METHOD...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S120463

    authors: Wang YP,Zhang W,Zhang J,Sun YP,An JL,Ding WY

    更新日期:2017-01-05 00:00:00

  • CBD Effects on TRPV1 Signaling Pathways in Cultured DRG Neurons.

    abstract:Introduction:Cannabidiol (CBD) is reported to produce pain relief, but the clinically relevant cellular and molecular mechanisms remain uncertain. The TRPV1 receptor integrates noxious stimuli and plays a key role in pain signaling. Hence, we conducted in vitro studies, to elucidate the efficacy and mechanisms of CBD f...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S258433

    authors: Anand U,Jones B,Korchev Y,Bloom SR,Pacchetti B,Anand P,Sodergren MH

    更新日期:2020-09-11 00:00:00

  • Stability of behavioral estimates of activity-dependent modulation of pain.

    abstract::Temporal sensory summation of pain (TSSP) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. Aftersensations (ASs) are pain sensations that remain after TSSP has been induced. We examined the within-session and across-session variabil...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S18105

    authors: Alappattu MJ,Bishop MD,Bialosky JE,George SZ,Robinson ME

    更新日期:2011-01-01 00:00:00

  • Erratum: Effect of Ultrasound-Guided Peripheral Nerve Blocks of the Abdominal Wall on Pain Relief After Laparoscopic Cholecystectomy [Corrigendum].

    abstract::[This corrects the article DOI: 10.2147/JPR.S203721.]. ...

    journal_title:Journal of pain research

    pub_type: 已发布勘误

    doi:10.2147/JPR.S278204

    authors:

    更新日期:2020-08-26 00:00:00

  • The relationship between findings on magnetic resonance imaging and previous history of low back pain.

    abstract::The objective of this study was to evaluate the relationship between magnetic resonance imaging (MRI) findings and previous low back pain (LBP) in participants without current LBP. Current LBP was defined as LBP during the past month. Previous LBP was defined as a history of medical consultation for LBP. Ninety-one pa...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S122380

    authors: Tonosu J,Oka H,Matsudaira K,Higashikawa A,Okazaki H,Tanaka S

    更新日期:2016-12-29 00:00:00

  • Conditioned pain modulation is minimally influenced by cognitive evaluation or imagery of the conditioning stimulus.

    abstract:PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S65607

    authors: Bernaba M,Johnson KA,Kong JT,Mackey S

    更新日期:2014-11-26 00:00:00

  • Peripheral and spinal TRPA1 channels contribute to formalin-induced long-lasting mechanical hypersensitivity.

    abstract:Background:Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by a subset of nociceptive neurons that acts as a multimodal receptor. Its activity contributes to modulate nociceptive transmission in acute inflammatory pain. However, the role of this channel in chronic pain has bee...

    journal_title:Journal of pain research

    pub_type: 杂志文章

    doi:10.2147/JPR.S153671

    authors: Martínez-Rojas VA,García G,Noriega-Navarro R,Guzmán-Priego CG,Torres-López JE,Granados-Soto V,Murbartián J

    更新日期:2017-12-27 00:00:00