The impact of multisite pain on functional outcomes in older adults: biopsychosocial considerations.

abstract：PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...

journal_title：Journal of pain research

authors： Bernaba M,Johnson KA,Kong JT,Mackey S

更新日期：2014-11-26 00:00:00

abstract：INTRODUCTION:Frequent chronic local pain can develop into chronic widespread pain (CWP). The spread of pain is correlated with pain intensity, anxiety, and depression, conditions that ultimately lead to a poor quality of life. Knowledge is incomplete about CWP's etiology, although it has been suggested that both centra...

journal_title：Journal of pain research

authors： Olausson P,Ghafouri B,Bäckryd E,Gerdle B

更新日期：2017-03-13 00:00:00

abstract：PURPOSE:The treatment of central neuropathic pain remains amongst the biggest challenges for pain specialists. The main objective of this study was to assess gabapentin (GBP), amitriptyline (AMI), and carbamazepine (CARBA) for the treatment of a rodent central neuropathic pain model. METHODS:Male Sprague Dawley rats w...

journal_title：Journal of pain research

authors： Castel A,Vachon P

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:While studies have demonstrated the economic burden of migraines in terms of quality of life, health care resource use (HRU), and costs, there exists a notable paucity of data comparing such outcomes among migraineurs with nausea and vomiting (N/V) and those without. The current study aimed to address this g...

journal_title：Journal of pain research

authors： Gajria K,Lee LK,Flores NM,Aycardi E,Gandhi SK

更新日期：2017-03-24 00:00:00

abstract：Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...

journal_title：Journal of pain research

authors： Gao Y,Zhou S,Pan Y,Gu L,He Y,Sun J

更新日期：2020-05-19 00:00:00

abstract：:Purpose: One of the main factor of cervical foraminal stenosis (CFS) is the hypertrophic change of the cervical facet joint. In order to analyze the connection between CFS and the facet joint hypertrophy, we devised a new morphological parameter, called the cervical facet joint cross-sectional area (CFJA). The CFJA ha...

journal_title：Journal of pain research

authors： An SJ,Hong SJ,Kim YU,Lee YK

更新日期：2019-04-24 00:00:00

abstract：Purpose:Although the use of opioids is increasing in South Korea, there have been no studies on the serious complications caused by the opioids. The aim of this study was to investigate the rare but serious complications through medicolegal analysis. Materials and Methods:From January 1994 to December 2019, we retrosp...

journal_title：Journal of pain research

authors： Kim J,Shin S,Jeong Y,Kim SY,Lee HJ

更新日期：2020-06-25 00:00:00

abstract：Purpose:The study aimed at the evaluation of the impact of intravenous (IV) dexamethasone on efficacy and duration of analgesia of paravertebral block (PVB) in patients undergoing modified radical mastectomy (MRM). Patients and methods:This randomized, double-blind controlled trial included 50 patients with breast can...

journal_title：Journal of pain research

authors： Bakeer AH,Abdallah NM,Kamel MA,Abbas DN,Ragab AS

更新日期：2018-12-19 00:00:00

abstract：PURPOSE:The zona incerta (ZI) is below the ventral tier of the thalamus and has a strong influence selectively in higher-order thalamic relays. Although neuropathic pain has been suggested to result from reduced gamma-aminobutyric acid (GABA) and GABAergic signaling in the ZI, the mechanisms remain unclear. Here, the r...

journal_title：Journal of pain research

authors： Moon HC,Park YS

更新日期：2017-05-11 00:00:00

abstract：:Low back pain in patients with myofascial pain syndrome is characterized by painful active myofascial trigger points (ATPs) in muscles. This article reviews a novel, noninvasive modality that combines simultaneous imaging and treatment, thus taking advantage of the electrodermal information available from imaged ATPs ...

journal_title：Journal of pain research

authors： Gorenberg M,Schwartz K

更新日期：2013-06-25 00:00:00

abstract：Background:Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by a subset of nociceptive neurons that acts as a multimodal receptor. Its activity contributes to modulate nociceptive transmission in acute inflammatory pain. However, the role of this channel in chronic pain has bee...

journal_title：Journal of pain research

authors： Martínez-Rojas VA,García G,Noriega-Navarro R,Guzmán-Priego CG,Torres-López JE,Granados-Soto V,Murbartián J

更新日期：2017-12-27 00:00:00

abstract：BACKGROUND:Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a serious medical and socioeconomic problem in recent decades. Patients suffering from chronic pain seem to have a higher prevalence of sleep disorders. PURPOSE:To calculate the prevalence of sleep deprivation in patients with CLBP and CNP...

journal_title：Journal of pain research

authors： Artner J,Cakir B,Spiekermann JA,Kurz S,Leucht F,Reichel H,Lattig F

更新日期：2013-01-01 00:00:00

abstract：Background:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis patients often present with psychiatric symptoms, cognitive dysfunction, epilepsy and memory deficits. A previous study has suggested that headache can occurr during the early stages of anti-NMDAR encephalitis. However, the exact association between hea...

journal_title：Journal of pain research

authors： Ma C,Wang C,Zhang Q,Lian Y

更新日期：2019-01-30 00:00:00

abstract：Purpose:Primary dysmenorrhea (PD; menstrual pain without an identified organic cause) has been proposed as a possible risk factor for the development of chronic pelvic pain, but the mechanism through which this process occurs is unknown. One possible mechanism is central sensitization - alterations in the central nervo...

journal_title：Journal of pain research

authors： Seidman LC,Temme CR,Zeltzer LK,Rapkin AJ,Naliboff BD,Payne LA

更新日期：2020-12-22 00:00:00

abstract：Background:Thoracoscopic surgery (TS) has been performed as a minimally invasive procedure since the beginning of the 1990s. This has led to a dramatic change in the postoperative condition of these patients, facilitating early ambulation and easier management of postoperative pain. However, empirical evidence on posto...

journal_title：Journal of pain research

authors： Kuroda H,Mizuno H,Dejima H,Watanabe K,Yoshida T,Naito Y,Sakao Y

更新日期：2017-11-15 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of ketoprofen in Transfersome® gel (IDEA-033) in comparison with a ketoprofen-free vehicle (TDT 064) for the treatment of osteoarthritis (OA) of the knee. METHODS:Patients with knee OA (N = 866) were randomly assigned to receive topical IDEA-033 containing 100, 50, or 25 m...

journal_title：Journal of pain research

authors： Kneer W,Rother M,Mazgareanu S,Seidel EJ,European IDEA-033 study group.

更新日期：2013-10-25 00:00:00

abstract：Background:Postherpetic neuralgia (PHN) refers to pain which remains after the healing of rashes from herpes zoster. Previous literatures have shown that acupuncture has potential benefits for PHN, but evidence remains lacking. Thus, we have performed a systematic review and meta-analysis to identify the effectiveness ...

journal_title：Journal of pain research

authors： Pei W,Zeng J,Lu L,Lin G,Ruan J

更新日期：2019-07-16 00:00:00

abstract：:Osteoarthritis (OA) is a common degenerative disease that affects the vast majority of the elderly and may eventually embark on the road of the total knee arthroplasty (TKA), although controversy still exists in the medical community about the best therapies for osteoarthritis. Compared with physical therapy, oral ana...

journal_title：Journal of pain research

authors： Zhang Y,Chen X,Tong Y,Luo J,Bi Q

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVE:The generic STarT Back 5-item screening tool (STarT-G) is used to manage chronic pain in the lower back and elsewhere. This study evaluated the validity of the Japanese version of this generic screening tool. MATERIALS AND METHODS:Japanese participants between the ages of 20 and 64 years completed online sur...

journal_title：Journal of pain research

authors： Oka H,Matsudaira K,Fujii T,Kikuchi N,Haga Y,Sawada T,Katsuhira J,Yoshimoto T,Kawamata K,Tonosu J,Sumitani M,Kasahara S,Tanaka S

更新日期：2017-02-24 00:00:00

abstract：Purpose:This study aimed to review and pool the current literature on intra-articular ozone injection in knee osteoarthritis (OA) patients. Methods:A systematic review of three big databases was performed to identify all English-language randomized clinical trials (RCTs) that evaluated the efficacy of intra-articular ...

journal_title：Journal of pain research

authors： Raeissadat SA,Tabibian E,Rayegani SM,Rahimi-Dehgolan S,Babaei-Ghazani A

更新日期：2018-10-25 00:00:00

abstract：Introduction:Sickle cell disease (SCD) is an inherited blood disorder characterized by abnormally shaped sickle cells. The hallmark of this disease is intermittent, painful vaso-occlusive episodes (VOE), but a subset of individuals with SCD experience chronic pain. The mechanism of transition to chronic pain is not wel...

journal_title：Journal of pain research

authors： Bakshi N,Lukombo I,Belfer I,Krishnamurti L

更新日期：2018-02-23 00:00:00

abstract：BACKGROUND:Opioids are the most important pharmacological treatment for moderate-to-severe cancer pain, but side effects limit their use. Transdermal fentanyl (TDF) and oral prolonged-release oxycodone-naloxone (OXN-PR) are effective in controlling chronic pain, with less constipation compared to other opioids. However...

journal_title：Journal of pain research

authors： Roberto A,Greco MT,Legramandi L,Galli F,Galli M,Corli O

更新日期：2017-09-04 00:00:00

abstract：INTRODUCTION:Although the majority of opioids in the US are prescribed by nonpain specialists, these providers often report inadequate training in chronic pain management and opioid prescribing. The extent of health care providers' knowledge of opioid prescribing for chronic pain has not been well established. The purp...

journal_title：Journal of pain research

authors： Pearson AC,Eldrige JS,Moeschler SM,Hooten WM

更新日期：2016-03-10 00:00:00

abstract：Background:Patients living with chronic upper limb and neck (ULN) pain are reliant on often ineffective therapies as they face limited options for effective long-term treatment. Objective:Prospective clinical studies have demonstrated that high-frequency spinal cord stimulation at 10 kHz (10 kHz SCS) is effective in t...

journal_title：Journal of pain research

authors： Sayed D,Salmon J,Khan TW,Sack AM,Braun T,Barnard A,Rotte A

更新日期：2020-06-15 00:00:00

abstract：Background:Many aspects of study conduct impact the observed effect size of treatment. Data were utilized from a recently published meta-analysis of randomized, double-blind, placebo-controlled, clinical trials performed for the United States Food and Drug Administration (FDA) approval of full mu-agonist opioids for th...

journal_title：Journal of pain research

authors： Meske DS,Vaughn BJ,Kopecky EA,Katz N

更新日期：2019-11-20 00:00:00

abstract：Background:Transversus abdominis plane (TAP) block can provide effective analgesia for abdominal surgery. However, many randomized controlled trials (RCTs) have shown controversial results in hysterectomy. We conducted a meta-analysis of RCTs to investigate the effectiveness of TAP block after hysterectomy. Methods:St...

journal_title：Journal of pain research

authors： Zhou H,Ma X,Pan J,Shuai H,Liu S,Luo X,Li R

更新日期：2018-10-18 00:00:00

abstract：:Cervical intervertebral disc has long been considered a common source of neck pain. However, the pain caused by the disc itself has not been clearly defined so far, and its diagnosis and treatment has always been controversial. Degenerative cervical disc has a rich supply of nerve fibers, is prone to inflammatory reac...

journal_title：Journal of pain research

authors： Peng B,DePalma MJ

更新日期：2018-11-14 00:00:00

abstract：Purpose:Brachial plexopathy can sometimes cause severe chronic pain. There are many possible treatments for such neuropathic pain, including neuromodulation. However, rigorous scientific evidence on the usefulness of spinal cord stimulation (SCS) is still scarce. Here, we report the use of high-frequency (10 kHz) SCS (...

journal_title：Journal of pain research

authors： Floridia D,Cerra F,Guzzo G,Marino S,Muscarà N,Corallo F,Bramanti A,Chillura A,Naro A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Low back pain is often called nonspecific pain. In this type of low back pain, various emotions and stress are known to strongly affect pain perception. The purpose of this study is to investigate how the degree of low back pain changes in people with chronic mild low back pain when they are inside and outsi...

journal_title：Journal of pain research

authors： Sakakibara T,Wang Z,Kasai Y

更新日期：2012-01-01 00:00:00

abstract：Purpose:To explore the role of cervical sagittal alignment in the occurrence of adjacent-level ossification development (ALOD) in patients who underwent anterior cervical discectomy fusion with self-locking stand-alone polyetheretherketone cage, and the relationship between cervical sagittal alignment and clinical outc...

journal_title：Journal of pain research

authors： Liu W,Rong Y,Chen J,Luo Y,Tang P,Zhou Z,Fan J,Cai W

更新日期：2018-07-20 00:00:00