Development and Prospect of Intra-Articular Injection in the Treatment of Osteoarthritis: A Review.

abstract：BACKGROUND:Opioids are the most important pharmacological treatment for moderate-to-severe cancer pain, but side effects limit their use. Transdermal fentanyl (TDF) and oral prolonged-release oxycodone-naloxone (OXN-PR) are effective in controlling chronic pain, with less constipation compared to other opioids. However...

journal_title：Journal of pain research

authors： Roberto A,Greco MT,Legramandi L,Galli F,Galli M,Corli O

更新日期：2017-09-04 00:00:00

abstract：:Neuromuscular blockade is a desirable or even essential component of general anesthesia for major surgical operations. As the population continues to age, and more operations are conducted in the elderly, due consideration must be given to neuromuscular blockade in these patients to avoid possible complications. This ...

journal_title：Journal of pain research

authors： Lee LA,Athanassoglou V,Pandit JJ

更新日期：2016-06-17 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the efficacy of percutaneous vertebroplasty (PVP) and interventional tumor removal (ITR), with PVP alone for malignant vertebral compression fractures and/or spinal metastatic tumor with epidural involvement. PATIENTS AND METHODS:A total of 124 patients were selected for ...

journal_title：Journal of pain research

authors： Gu YF,Tian QH,Li YD,Wu CG,Su Y,Song HM,He CJ,Chen D

更新日期：2017-01-20 00:00:00

abstract：BACKGROUND:One form of self-medication is sharing of medications, defined as borrowing or lending medications in situations where the receiver of these drugs is not the individual to whom the medications were allocated. OBJECTIVE:To explore experiences and opinions of patients about sharing prescription analgesics, re...

journal_title：Journal of pain research

authors： Markotic F,Vrdoljak D,Puljiz M,Puljak L

更新日期：2017-02-10 00:00:00

abstract：:Purpose: Thirty percent of patients with postherpetic neuralgia (PHN) receiving conservative treatment report unsatisfactory pain relief. Epidural steroid injections (ESIs) are commonly used as a therapeutic intervention in these patients. In this study, we aimed to determine if there are variables that predict the ef...

journal_title：Journal of pain research

authors： Ghanavatian S,Wie CS,Low RS,Butterfield RJ,Zhang N,Dhaliwal GS,Montoya JM,Swanson DL

更新日期：2019-04-23 00:00:00

abstract：OBJECTIVE:To evaluate the analgesic effectiveness of intra-articular botulinum toxin Type B (BoNT/B) in a murine model of chronic degenerative arthritis pain. METHODS AND MATERIALS:Chronic arthritis was produced in adult C57Bl6 mice by intra-articular injection of Type IV collagenase into the left knee. Following indu...

journal_title：Journal of pain research

authors： Anderson S,Krug H,Dorman C,McGarraugh P,Frizelle S,Mahowald M

更新日期：2010-09-06 00:00:00

abstract：:Duloxetine is a serotonin-norepinephrine reuptake inhibitor approved by the US Food and Drug Administration for the treatment of fibromyalgia and painful diabetic neuropathy at doses of 60 mg daily. Duloxetine has been shown to significantly improve the symptoms of chronic pain associated with these disorders, as meas...

journal_title：Journal of pain research

authors： Wright A,Luedtke KE,Vandenberg C

更新日期：2010-12-16 00:00:00

abstract：BACKGROUND:Detecting the efficacy of novel analgesic agents in neuropathic pain is challenging. There is a critical need for study designs with the desirable characteristics of assay sensitivity, low placebo response, reliable pain recordings, low cost, short duration of exposure to test drug and placebo, and relevant ...

journal_title：Journal of pain research

authors： Jenkins TM,Smart TS,Hackman F,Cooke C,Tan KK

更新日期：2012-01-01 00:00:00

abstract：:The observation of pain in others may enhance or reduce self-pain, yet the boundary conditions and factors that determine the direction of such effects are poorly understood. The current study set out to show that visual stimulus awareness plays a crucial role in determining whether vicarious pain primarily activates ...

journal_title：Journal of pain research

authors： Terrighena EL,Lu G,Yuen WP,Lee TM,Keuper K

更新日期：2017-07-31 00:00:00

abstract：INTRODUCTION:Pain is a common symptom presented in the emergency department (ED) although it is often underestimated, poorly evaluated and treated. The application of a protocol for timely pain management ensured by the nurse can avoid the delays in the analgesic treatment and improve the patient's quality of waiting. ...

journal_title：Journal of pain research

authors： Butti L,Bierti O,Lanfrit R,Bertolini R,Chittaro S,Delli Compagni S,Del Russo D,Mancusi RL,Pertoldi F

更新日期：2017-10-16 00:00:00

abstract：Objective:Chronic pain is a highly prevalent and costly condition with few proven treatment options. Since 2014, Geisinger's Department of Pain Medicine has implemented the Multidisciplinary Pain Program (MPP), which consists of a 3-day educational seminar followed by 12 months of comprehensive care. This study examine...

journal_title：Journal of pain research

authors： Maeng DD,Baylor K,Bulger JB,Han JJ

更新日期：2018-10-18 00:00:00

abstract：:Purpose: Although amiodarone is classified as a Vaughan-Williams class Ⅲ antiarrhythmic drug, it has inhibitory effects on voltage-gated sodium and calcium channels and on β-adrenergic receptors. Given these pharmacological profiles, amiodarone may have analgesic properties. Most patients who are prescribed amiodarone...

journal_title：Journal of pain research

authors： Kotoda M,Ino H,Kumakura Y,Iijima T,Ishiyama T,Matsukawa T

更新日期：2019-06-06 00:00:00

abstract：INTRODUCTION:Heat/capsaicin skin sensitization is a well-characterized human experimental model to induce hyperalgesia and allodynia. Using this model, gabapentin, among other drugs, was shown to significantly reduce cutaneous hyperalgesia compared to placebo. Since the larger thermal probes used in the original studie...

journal_title：Journal of pain research

authors： Cavallone LF,Frey K,Montana MC,Joyal J,Regina KJ,Petersen KL,Gereau RW 4th

更新日期：2013-11-07 00:00:00

abstract：Background and Aims:Plantar fasciitis (PF) is the leading cause of heel pain in adults. This study was designed to evaluate the effect of hyaluronic acid (HA) injection in reducing the symptoms of PF, compared with corticosteroid (CS) injection as a conventional treatment. Methods:In this triple-blind, randomized, cli...

journal_title：Journal of pain research

authors： Raeissadat SA,Nouri F,Darvish M,Esmaily H,Ghazihosseini P

更新日期：2020-01-14 00:00:00

abstract：Purpose:Brachial plexopathy can sometimes cause severe chronic pain. There are many possible treatments for such neuropathic pain, including neuromodulation. However, rigorous scientific evidence on the usefulness of spinal cord stimulation (SCS) is still scarce. Here, we report the use of high-frequency (10 kHz) SCS (...

journal_title：Journal of pain research

authors： Floridia D,Cerra F,Guzzo G,Marino S,Muscarà N,Corallo F,Bramanti A,Chillura A,Naro A

更新日期：2018-11-27 00:00:00

abstract：Aim:Operant conditioning has long been believed to influence the pain experience through a psychological reward pathway. This study was formulated to test the hypothesis that pain sensitivity may be enhanced >3 months if a monetary reward works as a reinforcement. Methods:Forty healthy subjects volunteered to particip...

journal_title：Journal of pain research

authors： Shiro Y,Ikemoto T,Hayashi K,Arai YC,Deie M,Ueno T

更新日期：2018-10-04 00:00:00

abstract：:Low back pain in patients with myofascial pain syndrome is characterized by painful active myofascial trigger points (ATPs) in muscles. This article reviews a novel, noninvasive modality that combines simultaneous imaging and treatment, thus taking advantage of the electrodermal information available from imaged ATPs ...

journal_title：Journal of pain research

authors： Gorenberg M,Schwartz K

更新日期：2013-06-25 00:00:00

abstract：BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...

journal_title：Journal of pain research

authors： Lionberger DR,Joussellin E,Lanzarotti A,Yanchick J,Magelli M

更新日期：2011-03-07 00:00:00

abstract：Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...

journal_title：Journal of pain research

authors： Chakravarthy K,Bink H,Dinsmoor D

更新日期：2020-12-04 00:00:00

abstract：Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...

journal_title：Journal of pain research

authors： Gao Y,Zhou S,Pan Y,Gu L,He Y,Sun J

更新日期：2020-05-19 00:00:00

abstract：PURPOSE:The aim of this study was to examine the health and economic burden associated with fibromyalgia among adults in Japan. MATERIALS AND METHODS:Data from the 2011-2014 Japan National Health and Wellness Survey (n=115,271), a nationally representative survey of adults, were analyzed. The greedy matching algorithm...

journal_title：Journal of pain research

authors： Lee LK,Ebata N,Hlavacek P,DiBonaventura M,Cappelleri JC,Sadosky A

更新日期：2016-11-04 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is a major player in migraine pathophysiology, and CGRP monoclonal antibodies including fremanezumab may be a safe effective preventive therapy. Phase IIb studies in episodic migraine (EM) and chronic migraine (CM) demonstrated efficacy at both the monthly 225 mg and quarterly 67...

journal_title：Journal of pain research

authors： Robblee J,VanderPluym J

更新日期：2019-08-22 00:00:00

abstract：:Background: Chronic neuropathic pain (NP) is a complex disease that results from damage or presumed damage to the somatosensory nervous system. Current treatment regimens are often ineffective. The major impediment in developing effective treatments is our limited understanding of the underlying mechanisms. Preclinica...

journal_title：Journal of pain research

authors： Alshelh Z,Mills EP,Kosanovic D,Di Pietro F,Macey PM,Vickers ER,Henderson LA

更新日期：2019-08-02 00:00:00

abstract：Purpose:Erector spinae plane block (ESPB) is a newly reported interfascial plane block in pain management, and it can block the nerves exactly in line with the area of the posterior lumbar surgery. The objective of this research was to determine the effectiveness of pre-operative ESPB in enhancing recovery of posterior...

journal_title：Journal of pain research

authors： Zhang TJ,Zhang JJ,Qu ZY,Zhang HY,Qiu Y,Hua Z

更新日期：2020-04-05 00:00:00

abstract：:Ultrasound-guided cervical nerve root block is the technique of injecting local anesthetic or steroid into the intertubercular groove outside of the cervical foramen under real-time ultrasound guidance. It has established diagnostic and therapeutic employment for patients suffering symptoms caused by cervical disc dis...

journal_title：Journal of pain research

authors： Zhang S,Fan L,Mei W

更新日期：2020-10-14 00:00:00

abstract：Background:To date, there has been no study on the effects of interleukin-10 (IL-10) on complex regional pain syndrome (CRPS) rodent models, despite the anti-allodynic effect of IL-10 in previous studies. Thus, the aim of this study was to investigate the effect of IL-10 in a CRPS mouse model and find whether early inh...

journal_title：Journal of pain research

authors： Kim JH,Park JS,Park D

更新日期：2018-09-04 00:00:00

abstract：Background:Pancreatic cancer is a malignant disease with a high mortality rate and severe pain that is challenging to manage. To reduce the excruciating abdominal pain, opioids and adjuvant agents are conventionally used. Objectives:PRNCPB is a treatment of neural therapy. The number of studies assessing the effect on...

journal_title：Journal of pain research

authors： Molnár I,Hegyi G,Zsom L,Saahs C,Vagedes J,Kapócs G,Kovács Z,Sterner MG,Szőke H

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:Waiting list management at chronic pain clinics has become a serious problem throughout Canada. We analyzed the waiting list at the Centre hospitalier de l'Université de Montréal (CHUM) Pain Centre. METHODS:The present study is an observational, prospective study. We used a specifically designed survey ques...

journal_title：Journal of pain research

authors： Vargas-Schaffer G,Rusnov A,Boulanger A

更新日期：2013-07-08 00:00:00

abstract：Purpose:To investigate the ameliorative effects of Vitellaria paradoxa (VP) nut extract for an anterior cruciate ligament transection with medial meniscectomy (ACLT+MMx)-induced osteoarthritis (OA) in high-fat diet (HFD)-induced obese rats. Methods:The rats were fed by HFD for 5 weeks before surgery-induced OA. Rats w...

journal_title：Journal of pain research

authors： Sudirman S,Chen CK,Long BT,Chang HW,Tsou D,Kong ZL

更新日期：2020-01-30 00:00:00

abstract：Purpose:Complex regional pain syndrome (CRPS) is a rare but refractory pain disorder. Recent advanced information retrieval studies using text-mining and network analysis have suggested nuclear factor kappa B (NFκB) as a possible central mediator of CRPS. The brain is also known to play important roles in CRPS. The aim...

journal_title：Journal of pain research

authors： Nahm FS,Nahm SS,Han WK,Gil HY,Choi E,Lee PB

更新日期：2019-03-06 00:00:00